Techniques for detecting glucose are developing at a breathtaking speed because diabetes mellitus can cause many serious complications, such as blindness, high blood pressure heart disease and kidney failure. Herein, ...Techniques for detecting glucose are developing at a breathtaking speed because diabetes mellitus can cause many serious complications, such as blindness, high blood pressure heart disease and kidney failure. Herein, water sol- uble NaYF4:Eu^3+@Ag core-shell nanocrystals for glucose de- tection with lower detection limit have been successfully de- veloped, using NaYF4:Eu^3+ cores as the energy donors and Ag shells as the efficient quenchers through energy transfer. After immobilization of glucose oxidase (GOx) on the sur- face of NaYF4:Eu^3+@Ag core-shell nanocrystals, the Ag shells can be decomposed in the presence of glucose, accompanied by down-shifting luminescence recovery. The limit of detec- tion of NaYF4:Eu^3+@Ag was 0.12 μmol L^-1. Therefore, the NaYF4:Eu^3+@Ag can be easily extended to the detection of a variety of H2O2-involved analytes.展开更多
基金supported by the National Natural Science Foundation of China(21471050 and 21501052)the China Postdoctoral Science Foundation(2015M570304)+2 种基金the Postdoctoral Science Foundation of Heilongjiang Province(LBH-TZ06019)the Natural Science Foundation of Heilongjiang Province(ZD201301d)the Science Foundation for Excellent Youth of Harbin City of China (2016RQQXJ099)
文摘Techniques for detecting glucose are developing at a breathtaking speed because diabetes mellitus can cause many serious complications, such as blindness, high blood pressure heart disease and kidney failure. Herein, water sol- uble NaYF4:Eu^3+@Ag core-shell nanocrystals for glucose de- tection with lower detection limit have been successfully de- veloped, using NaYF4:Eu^3+ cores as the energy donors and Ag shells as the efficient quenchers through energy transfer. After immobilization of glucose oxidase (GOx) on the sur- face of NaYF4:Eu^3+@Ag core-shell nanocrystals, the Ag shells can be decomposed in the presence of glucose, accompanied by down-shifting luminescence recovery. The limit of detec- tion of NaYF4:Eu^3+@Ag was 0.12 μmol L^-1. Therefore, the NaYF4:Eu^3+@Ag can be easily extended to the detection of a variety of H2O2-involved analytes.