Objective： This paper was designed to confirm the efficacy of chewing carboxymethyl chitosan（CMCTS）-containing gum in suppressing the growth of oral bacteria when compared to a CMCTS-containing mouth rinse. Methods...Objective： This paper was designed to confirm the efficacy of chewing carboxymethyl chitosan（CMCTS）-containing gum in suppressing the growth of oral bacteria when compared to a CMCTS-containing mouth rinse. Methods：Fourteen healthy subjects were recruited from among the staff and students of Qingdao University Dentistry Department. Before the experiments saliva was collected from all subjects and bacteria counts determined. For the gum study, the subjects chewed CMCTS-containing gum for 5 min and then rested for 5 min. When testing the CMCTS mouth rinse, the subjects gargled with 10 mL of solution for 30 s, followed by resting for 9rain 30 s. These protocols were repeated five times over a 50 min period on the same day. Post-experiment saliva samples were then collected at the following times： 0, 30 and 60 min. Results： Chewing gum containing CMCTS or rinsing with a CMCTS-containing rinse significantly decreased oral bacteria counts. The total bacteria counts, total Streptococci counts, and mutans streptococci counts of saliva from subjects who chewed CMCTS-containing gum were significantly lower than saliva from subjects in the rinse group in all three sampling periods, except in the case of the total bacteria count in the 60 min samples. Conclusion：CMCTS-containing gum chewing has a greater antibac- terial effect than using a CMCTS-containing mouth rinse. The present findings strongly indicate that the application of natural materials such as chitosan and its derivatives is useful for better oral health.展开更多
目的探讨康复新液联合西帕依固龈液治疗固定正畸早期牙龈炎的临床疗效。方法选取2012年1月—2017年5月南阳南石医院口腔科收治的固定正畸早期牙龈炎患者120例进行研究,按随机数字表法将所有患者分为对照组和治疗组,每组各60例。对照组...目的探讨康复新液联合西帕依固龈液治疗固定正畸早期牙龈炎的临床疗效。方法选取2012年1月—2017年5月南阳南石医院口腔科收治的固定正畸早期牙龈炎患者120例进行研究,按随机数字表法将所有患者分为对照组和治疗组,每组各60例。对照组在固定正畸治疗后,分别于晨起后、晚睡前、3餐后含漱西帕依固龈液,5~10 m L/次,含漱3 min。治疗组于含漱西帕依固龈液15 min后含漱康复新液,5~10 m L/次,含漱3 min。以4周为1个疗程,两组患者均治疗6个疗程。观察两组的临床疗效,比较两组的简化口腔卫生指数(OHI-S)、牙龈指数(GI)、牙龈探诊出血(BOP)、菌斑指数(PLI)和并发症情况。结果治疗后,对照组和治疗组的总有效率分别为80.00%、91.67%,两组比较差异具有统计学意义(P<0.05)。治疗3、6个月后,两组OHI-S、GI、PLI和BOP均升高,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标均高于对照组,两组比较差异具有统计学意义(P<0.05)。对照组和治疗组的并发症分别为21.67%、8.33%,两组比较差异有统计学意义(P<0.05)。结论康复新液联合西帕依固龈液治疗固定正畸早期牙龈炎具有较好的临床疗效,可改善牙龈出血、口腔卫生等牙周指标,减少并发症,具有一定的临床推广应用价值。展开更多
文摘Objective： This paper was designed to confirm the efficacy of chewing carboxymethyl chitosan（CMCTS）-containing gum in suppressing the growth of oral bacteria when compared to a CMCTS-containing mouth rinse. Methods：Fourteen healthy subjects were recruited from among the staff and students of Qingdao University Dentistry Department. Before the experiments saliva was collected from all subjects and bacteria counts determined. For the gum study, the subjects chewed CMCTS-containing gum for 5 min and then rested for 5 min. When testing the CMCTS mouth rinse, the subjects gargled with 10 mL of solution for 30 s, followed by resting for 9rain 30 s. These protocols were repeated five times over a 50 min period on the same day. Post-experiment saliva samples were then collected at the following times： 0, 30 and 60 min. Results： Chewing gum containing CMCTS or rinsing with a CMCTS-containing rinse significantly decreased oral bacteria counts. The total bacteria counts, total Streptococci counts, and mutans streptococci counts of saliva from subjects who chewed CMCTS-containing gum were significantly lower than saliva from subjects in the rinse group in all three sampling periods, except in the case of the total bacteria count in the 60 min samples. Conclusion：CMCTS-containing gum chewing has a greater antibac- terial effect than using a CMCTS-containing mouth rinse. The present findings strongly indicate that the application of natural materials such as chitosan and its derivatives is useful for better oral health.
文摘目的探讨康复新液联合西帕依固龈液治疗固定正畸早期牙龈炎的临床疗效。方法选取2012年1月—2017年5月南阳南石医院口腔科收治的固定正畸早期牙龈炎患者120例进行研究,按随机数字表法将所有患者分为对照组和治疗组,每组各60例。对照组在固定正畸治疗后,分别于晨起后、晚睡前、3餐后含漱西帕依固龈液,5~10 m L/次,含漱3 min。治疗组于含漱西帕依固龈液15 min后含漱康复新液,5~10 m L/次,含漱3 min。以4周为1个疗程,两组患者均治疗6个疗程。观察两组的临床疗效,比较两组的简化口腔卫生指数(OHI-S)、牙龈指数(GI)、牙龈探诊出血(BOP)、菌斑指数(PLI)和并发症情况。结果治疗后,对照组和治疗组的总有效率分别为80.00%、91.67%,两组比较差异具有统计学意义(P<0.05)。治疗3、6个月后,两组OHI-S、GI、PLI和BOP均升高,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标均高于对照组,两组比较差异具有统计学意义(P<0.05)。对照组和治疗组的并发症分别为21.67%、8.33%,两组比较差异有统计学意义(P<0.05)。结论康复新液联合西帕依固龈液治疗固定正畸早期牙龈炎具有较好的临床疗效,可改善牙龈出血、口腔卫生等牙周指标,减少并发症,具有一定的临床推广应用价值。
