Objective:To describe the long-term outcomes of cases of neovascular glaucoma drained by Molteno implants.Methods:A prospective study of 145 eyes(130 patients)followed up for a mean of 3.3 years(range,0.02 year 5 days...Objective:To describe the long-term outcomes of cases of neovascular glaucoma drained by Molteno implants.Methods:A prospective study of 145 eyes(130 patients)followed up for a mean of 3.3 years(range,0.02 year 5 days to 18.1 years)in the province of Otago,New Zealand,from 1979 to 2002.Results:Insertion of a Molteno implant controlled the intraocular pressure at 21 mmHg or less with a probability(95% confidence interval)of 0.72(0.64-0.80),0.60(0.51-0.69),and 0.40(0.29-0.50)at 1,2,and 5 years,respectively.Failure to control intraocular pressure at 1,2,and 5 years was significantly correlated with persistent iris neovascularization(P<.001,P<.001,and P=.01,respectively).Visual acuity at final follow-up in non-enucleated eyes was maintained or improved in 56 eyes(39%)and deteriorated to light perception or better in 25(17%)or no light perception in 47(32%).Seventeen eyes(12%)were enucleated.Conclusions:The insertion of Molteno implants for neovascular glaucoma maintained or improved vision in 39% of eyes,whereas 12% were eventually enucleated(all of which initially had visual acuity < 20/1200).The outcome depended mainly on progression of the underlying vascular disease.展开更多
文摘Objective:To describe the long-term outcomes of cases of neovascular glaucoma drained by Molteno implants.Methods:A prospective study of 145 eyes(130 patients)followed up for a mean of 3.3 years(range,0.02 year 5 days to 18.1 years)in the province of Otago,New Zealand,from 1979 to 2002.Results:Insertion of a Molteno implant controlled the intraocular pressure at 21 mmHg or less with a probability(95% confidence interval)of 0.72(0.64-0.80),0.60(0.51-0.69),and 0.40(0.29-0.50)at 1,2,and 5 years,respectively.Failure to control intraocular pressure at 1,2,and 5 years was significantly correlated with persistent iris neovascularization(P<.001,P<.001,and P=.01,respectively).Visual acuity at final follow-up in non-enucleated eyes was maintained or improved in 56 eyes(39%)and deteriorated to light perception or better in 25(17%)or no light perception in 47(32%).Seventeen eyes(12%)were enucleated.Conclusions:The insertion of Molteno implants for neovascular glaucoma maintained or improved vision in 39% of eyes,whereas 12% were eventually enucleated(all of which initially had visual acuity < 20/1200).The outcome depended mainly on progression of the underlying vascular disease.
