Model organisms have long been important in biology and medicine due to their specific characteristics. Amphibians, especially Xenopus, play key roles in answering fundamental questions on developmental biology, regen...Model organisms have long been important in biology and medicine due to their specific characteristics. Amphibians, especially Xenopus, play key roles in answering fundamental questions on developmental biology, regeneration, genetics, and toxicology due to their large and abundant eggs, as well as their versatile embryos, which can be readily manipulated and developed in vivo. Furthermore, amphibians have also proven to be of considerable benefit in human disease research due to their conserved cellular developmental and genomic organization. This review gives a brief introduction on the progress and limitations of these animal models in biology and human disease research, and discusses the potential and challenge of Microhyla fissipes as a new model organism.展开更多
We described a new species, Microhyla beilunensis sp. nov., from Zhejiang Province of China. Phylogenetic analyses based on the mitochondrial 12 S, 16 S and CO1 gene sequences suggested that the new taxon was distinct...We described a new species, Microhyla beilunensis sp. nov., from Zhejiang Province of China. Phylogenetic analyses based on the mitochondrial 12 S, 16 S and CO1 gene sequences suggested that the new taxon was distinctly separated from its congeners and closed to M. mixtura and M. okinavensis. Morphologically, the new species could be identified from its congeners except M. mixtura by several characters：（1） rudimentary webs on toe base;（2） absence of disks and dorsal median longitudinal grooves on finger tips;（3） presence of disks and dorsal median longitudinal grooves on toe tips. As well, the new species could be identified from topotype M. mixtura by the combination of characters：（1） apart from the stripes, bar-shaped and oval-shaped patterns, the rounded spots present on the dorsum of body and legs;（2） the outer metacarpal tubercles prominently larger than the inner one;（3） of males, the ratios of HW, IND, UEW and LAW to SVL of the new species were significantly larger than those of M. mixtura（P 〈 0.01）, and the ratios of SL, IOD, LAHL, HLL, TL, TFL and FL to SVL of the new species were significantly less than those of M. mixtura（P 〈 0.05）.展开更多
We describe a new species,Microh yla hongiaoensis sp.nov.,from Lam Dong Province,southern Vietnam based on morphological data and molecular evidences.The new species is sister to M.pulchella by molecular phylogenetics...We describe a new species,Microh yla hongiaoensis sp.nov.,from Lam Dong Province,southern Vietnam based on morphological data and molecular evidences.The new species is sister to M.pulchella by molecular phylogenetics and also most closely resembles M.pulchella in morphological characteristics,albeit differs from its congeners by a combination of the following morphological features:(1)size medium(SVL 13.6-14.7 mm in males and 18.3-18.6 mm in females);(2)fingers Ⅱ-Ⅳ with small disks,dorsal surface of disks,without median longitudinal groove;(3)webbing formula Ⅰ11/2 Ⅱ1-2 Ⅲ1-21/2Ⅳ21/4-1 Ⅴ;(4)toe disks with dorsal median longitudinal groove;(5)dorsal back without two small black spots;(6)one small black spot adjacent behind the eyes;(7)few small black scapular spots in the flanks-belly and inguinal region;(8)palm with two small metatarsal tubercles;(9)tibiotarsal reaching beyond snout.M.hongiaoensis sp.nov.occurs in evergreen montane tropical forests at an elevation of 1500 m a.s.l.展开更多
The 3 species of Hubei’s new records on amphibians and reptile are collected in Jiugong mountain natural reserve from July 14th,1999 to July 21th,1999.They are Microhyla heymonsi Vogt,whose specimens are kept in Jiug...The 3 species of Hubei’s new records on amphibians and reptile are collected in Jiugong mountain natural reserve from July 14th,1999 to July 21th,1999.They are Microhyla heymonsi Vogt,whose specimens are kept in Jiugong mountain natural reserve; Odorrana livida Blyth, whose specimens are kept in Jiugong mountain natura reserve; Opisthotropis latouchii Boulenger, whose specimen is kept in the College of Life Science, Central China Normal University.展开更多
基金supported by a grant from the Key Programs of the Chinese Academy of Sciences(KJZD-EW-L13)2015 Western Light Talent Culture Project of the Chinese Academy of Sciences(Y6C3021)the National Natural Science Foundation of China(31471964)
文摘Model organisms have long been important in biology and medicine due to their specific characteristics. Amphibians, especially Xenopus, play key roles in answering fundamental questions on developmental biology, regeneration, genetics, and toxicology due to their large and abundant eggs, as well as their versatile embryos, which can be readily manipulated and developed in vivo. Furthermore, amphibians have also proven to be of considerable benefit in human disease research due to their conserved cellular developmental and genomic organization. This review gives a brief introduction on the progress and limitations of these animal models in biology and human disease research, and discusses the potential and challenge of Microhyla fissipes as a new model organism.
基金supported by National Key Programme of Research and Development, Ministry of Science and Technology (2017YFC0505202)National Natural Sciences Foundation of China (NSFC31471964 and 31201702)+1 种基金Important Research Project of Chinese Academy of Sciences (KJZG-EW-L13)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA19050201)
文摘We described a new species, Microhyla beilunensis sp. nov., from Zhejiang Province of China. Phylogenetic analyses based on the mitochondrial 12 S, 16 S and CO1 gene sequences suggested that the new taxon was distinctly separated from its congeners and closed to M. mixtura and M. okinavensis. Morphologically, the new species could be identified from its congeners except M. mixtura by several characters：（1） rudimentary webs on toe base;（2） absence of disks and dorsal median longitudinal grooves on finger tips;（3） presence of disks and dorsal median longitudinal grooves on toe tips. As well, the new species could be identified from topotype M. mixtura by the combination of characters：（1） apart from the stripes, bar-shaped and oval-shaped patterns, the rounded spots present on the dorsum of body and legs;（2） the outer metacarpal tubercles prominently larger than the inner one;（3） of males, the ratios of HW, IND, UEW and LAW to SVL of the new species were significantly larger than those of M. mixtura（P 〈 0.01）, and the ratios of SL, IOD, LAHL, HLL, TL, TFL and FL to SVL of the new species were significantly less than those of M. mixtura（P 〈 0.05）.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA23080101)NSFC(31471964)+2 种基金The World Academy of Sciences(TWAS)CAS-TWAS president fellowship programRFBR 19-54-54003 Vietnam,and Ideal Wild。
文摘We describe a new species,Microh yla hongiaoensis sp.nov.,from Lam Dong Province,southern Vietnam based on morphological data and molecular evidences.The new species is sister to M.pulchella by molecular phylogenetics and also most closely resembles M.pulchella in morphological characteristics,albeit differs from its congeners by a combination of the following morphological features:(1)size medium(SVL 13.6-14.7 mm in males and 18.3-18.6 mm in females);(2)fingers Ⅱ-Ⅳ with small disks,dorsal surface of disks,without median longitudinal groove;(3)webbing formula Ⅰ11/2 Ⅱ1-2 Ⅲ1-21/2Ⅳ21/4-1 Ⅴ;(4)toe disks with dorsal median longitudinal groove;(5)dorsal back without two small black spots;(6)one small black spot adjacent behind the eyes;(7)few small black scapular spots in the flanks-belly and inguinal region;(8)palm with two small metatarsal tubercles;(9)tibiotarsal reaching beyond snout.M.hongiaoensis sp.nov.occurs in evergreen montane tropical forests at an elevation of 1500 m a.s.l.
文摘The 3 species of Hubei’s new records on amphibians and reptile are collected in Jiugong mountain natural reserve from July 14th,1999 to July 21th,1999.They are Microhyla heymonsi Vogt,whose specimens are kept in Jiugong mountain natural reserve; Odorrana livida Blyth, whose specimens are kept in Jiugong mountain natura reserve; Opisthotropis latouchii Boulenger, whose specimen is kept in the College of Life Science, Central China Normal University.
