目的:观察掀针联合胃复安穴位注射治疗食管癌患者顺铂联合5-氟尿嘧啶(PF)方案化疗引起的恶心、呕吐的疗效。方法:64例接受PF方案化疗期间出现恶心呕吐的食管癌患者依据随机数字表法随机平均分为研究组和对照组。对照组给予胃复安穴位注...目的:观察掀针联合胃复安穴位注射治疗食管癌患者顺铂联合5-氟尿嘧啶(PF)方案化疗引起的恶心、呕吐的疗效。方法:64例接受PF方案化疗期间出现恶心呕吐的食管癌患者依据随机数字表法随机平均分为研究组和对照组。对照组给予胃复安穴位注射,研究组在对照组治疗基础上给予掀针。两组均连续治疗3 d。治疗后,比较两组患者治疗前后恶心、呕吐中医证候积分,恶心呕吐消失率;比较两组患者治疗前、化疗结束时生存质量[采用癌症患者生存质量测定量表体系(quality of life instruments for cancer patients,QLICP)评估]。结果:治疗后,研究组恶心、呕吐中医证候积分及消失率低于对照组(P<0.05);化疗结束时,研究组QLICP中各维度评分高于对照组(P<0.05)。结论:掀针联合胃复安穴位注射可有效减轻患者化疗相关恶心呕吐消化道症状,改善患者生存质量。展开更多
Simple and sensitive normal and reverse flow injection methods for spectrophotometric determination of thiamine hydrochloride (THC) at the microgram level were proposed and optimized. Both methods are based on the r...Simple and sensitive normal and reverse flow injection methods for spectrophotometric determination of thiamine hydrochloride (THC) at the microgram level were proposed and optimized. Both methods are based on the reaction between THC and diazotized metoclopramide in alkaline medium. Beer's law was obeyed over the range of 10 300 and 2-90 ug/mL, the limits of detection were 2.118 and 0.839 ug/mL and the sampling rates were 80 and 95 injections per hour for normal and reverse flow injection methods respectively. The application of both methods to commercially available pharmaceuticals produced acceptable results. The flow system is suitable for application in quality control processes.展开更多
目的评价食管心房调搏前肌内注射甲氧氯普胺注射液对电极安放耗时和安全性的影响。方法选择2012年2月至2013年5于泸州市中医医院心血管内科门诊行食管心房调搏检查的患者80例,依据计算机软件编制随机分配表将患者分为试验组(42例)和对照...目的评价食管心房调搏前肌内注射甲氧氯普胺注射液对电极安放耗时和安全性的影响。方法选择2012年2月至2013年5于泸州市中医医院心血管内科门诊行食管心房调搏检查的患者80例,依据计算机软件编制随机分配表将患者分为试验组(42例)和对照组(38例)。两组均于食管心房调搏前肌内注射药物1 m L(试验组为甲氧氯普胺注射液1 m L/10 mg,对照组为0.9%氯化钠注射液1 m L,两组均为无色透明液体),观察经鼻食管电极安放平均耗时及安全性(误吸及恶心呕吐)。结果试验组电极安放平均耗时较对照组显著缩短,差异有统计学意义(P<0.05);试验组患者0例出现误吸,对照组患者1例,差异无统计学意义(P>0.05);恶心呕吐评级比较,试验组安全性优于对照组(P<0.05)。结论在食管心房调搏前肌注甲氧氯普胺注射液能明显缩短电极安放时间,提高电极安放的安全性,减轻患者痛苦。展开更多
文摘目的:观察掀针联合胃复安穴位注射治疗食管癌患者顺铂联合5-氟尿嘧啶(PF)方案化疗引起的恶心、呕吐的疗效。方法:64例接受PF方案化疗期间出现恶心呕吐的食管癌患者依据随机数字表法随机平均分为研究组和对照组。对照组给予胃复安穴位注射,研究组在对照组治疗基础上给予掀针。两组均连续治疗3 d。治疗后,比较两组患者治疗前后恶心、呕吐中医证候积分,恶心呕吐消失率;比较两组患者治疗前、化疗结束时生存质量[采用癌症患者生存质量测定量表体系(quality of life instruments for cancer patients,QLICP)评估]。结果:治疗后,研究组恶心、呕吐中医证候积分及消失率低于对照组(P<0.05);化疗结束时,研究组QLICP中各维度评分高于对照组(P<0.05)。结论:掀针联合胃复安穴位注射可有效减轻患者化疗相关恶心呕吐消化道症状,改善患者生存质量。
文摘Simple and sensitive normal and reverse flow injection methods for spectrophotometric determination of thiamine hydrochloride (THC) at the microgram level were proposed and optimized. Both methods are based on the reaction between THC and diazotized metoclopramide in alkaline medium. Beer's law was obeyed over the range of 10 300 and 2-90 ug/mL, the limits of detection were 2.118 and 0.839 ug/mL and the sampling rates were 80 and 95 injections per hour for normal and reverse flow injection methods respectively. The application of both methods to commercially available pharmaceuticals produced acceptable results. The flow system is suitable for application in quality control processes.
文摘目的评价食管心房调搏前肌内注射甲氧氯普胺注射液对电极安放耗时和安全性的影响。方法选择2012年2月至2013年5于泸州市中医医院心血管内科门诊行食管心房调搏检查的患者80例,依据计算机软件编制随机分配表将患者分为试验组(42例)和对照组(38例)。两组均于食管心房调搏前肌内注射药物1 m L(试验组为甲氧氯普胺注射液1 m L/10 mg,对照组为0.9%氯化钠注射液1 m L,两组均为无色透明液体),观察经鼻食管电极安放平均耗时及安全性(误吸及恶心呕吐)。结果试验组电极安放平均耗时较对照组显著缩短,差异有统计学意义(P<0.05);试验组患者0例出现误吸,对照组患者1例,差异无统计学意义(P>0.05);恶心呕吐评级比较,试验组安全性优于对照组(P<0.05)。结论在食管心房调搏前肌注甲氧氯普胺注射液能明显缩短电极安放时间,提高电极安放的安全性,减轻患者痛苦。