Virtual reality is a new technology that simulates a three-dimensional virtual world on a com- puter and enables the generation of visual, audio, and haptic feedback for the full immersion of users. Users can interact...Virtual reality is a new technology that simulates a three-dimensional virtual world on a com- puter and enables the generation of visual, audio, and haptic feedback for the full immersion of users. Users can interact with and observe objects in three-dimensional visual space without limitation. At present, virtual reality training has been widely used in rehabilitation therapy for balance dysfunction. This paper summarizes related articles and other articles suggesting that virtual reality training can improve balance dysfunction in patients after neurological diseases. When patients perform virtual reality training, the prefrontal, parietal cortical areas and other motor cortical networks are activated. These activations may be involved in the reconstruction of neurons in the cerebral cortex. Growing evidence from clinical studies reveals that virtual reality training improves the neurological function of patients with spinal cord injury, cerebral palsy and other neurological impairments. These findings suggest that virtual reality training can acti- vate the cerebral cortex and improve the spatial orientation capacity of patients, thus facilitating the cortex to control balance and increase motion function.展开更多
运用胜率标准差、赫芬达尔HHI指数、TOP K ranking等统计指标,对中美男子篮球职业联赛2008/2009—2003/2014赛季常规赛俱乐部之间竞争平衡进行对比分析。研究结果表明:在2008/2009—2003/2014常规赛赛季中,NBA职业联赛具有良好的平衡机...运用胜率标准差、赫芬达尔HHI指数、TOP K ranking等统计指标,对中美男子篮球职业联赛2008/2009—2003/2014赛季常规赛俱乐部之间竞争平衡进行对比分析。研究结果表明:在2008/2009—2003/2014常规赛赛季中,NBA职业联赛具有良好的平衡机制,平衡机制相对于CBA职业联赛较为完善。各测度指标进一步证明了NBA球队之间竞争实力更加平衡,比赛更具悬念和观赏性。我国CBA联赛与NBA联赛相比,球队之间竞争平衡机制不完善,导致球队之间竞赛水平差异较大,比赛缺乏观赏性。CBA联赛应借鉴NBA制衡机制的成功经验,细化选秀制度和转会制度,逐步完善后备人才的培养体系,使CBA职业篮球运动水平有显著的提高。展开更多
随着电网结构的日益复杂,变电站关键设备的运行状态对电网安全稳定运行的影响逐渐增强。针对变电站复杂背景下多目标识别以及相似目标识别困难的问题,该文提出了一种基于注意力机制与特征平衡的YOLO-AFB(you only look once-attention a...随着电网结构的日益复杂,变电站关键设备的运行状态对电网安全稳定运行的影响逐渐增强。针对变电站复杂背景下多目标识别以及相似目标识别困难的问题,该文提出了一种基于注意力机制与特征平衡的YOLO-AFB(you only look once-attention and feature balance)网络。通过在Darknet-53网络中引入混合注意力加强对变电站相关目标的特征提取能力,在特征融合模块中加入反卷积来实现特征图的自适应上采样,提出特征平衡策略来缓解特征图语义信息差别,提高特征融合的质量。在含有9类目标的变电站数据集上进行测试,所提模型整体识别精度达到了83.02%,与经典目标检测网络对比,各类目标的检测精度均有大幅提升。同时互感器等相似目标的识别也得到明显改善,验证了特征平衡的策略可以很好地解决变电站中相似目标识别难的问题。展开更多
The AMP-activated protein kinase(AMPK)is a sensor of cellular energy status that is almost universally expressed in eukaryotic cells.While it appears to have evolved in single-celled eukaryotes to regulate energy bala...The AMP-activated protein kinase(AMPK)is a sensor of cellular energy status that is almost universally expressed in eukaryotic cells.While it appears to have evolved in single-celled eukaryotes to regulate energy balance in a cell-autonomous manner,during the evolution of multicellular animals its role has become adapted so that it also regulates energy balance at the whole body level,by responding to hormones that act primarily on the hypothalamus.AMPK monitors energy balance at the cellular level by sensing the ratios of AMP/ATP and ADP/ATP,and recent structural analyses of the AMPK heterotrimer that have provided insight into the complex mechanisms for these effects will be discussed.Given the central importance of energy balance in diseases that are major causes of morbidity or death in humans,such as type 2 diabetes,cancer and inflammatory disorders,there has been a major drive to develop pharmacological activators of AMPK.Many such activators have been described,and the various mechanisms by which these activate AMPK will be discussed.A particularly large class of AMPK activators are natural products of plants derived from traditional herbal medicines.While the mechanism by which most of these activate AMPK has not yet been addressed,I will argue that many of them may be defensive compounds produced by plants to deter infection by pathogens or grazing by insects or herbivores,and that many of them will turn out to be inhibitors of mitochondrial function.展开更多
基金supported by the National Natural Science Foundation of China,No.30973165 and 81372108Guangdong Province College Students Innovative Research Projects in 2013
文摘Virtual reality is a new technology that simulates a three-dimensional virtual world on a com- puter and enables the generation of visual, audio, and haptic feedback for the full immersion of users. Users can interact with and observe objects in three-dimensional visual space without limitation. At present, virtual reality training has been widely used in rehabilitation therapy for balance dysfunction. This paper summarizes related articles and other articles suggesting that virtual reality training can improve balance dysfunction in patients after neurological diseases. When patients perform virtual reality training, the prefrontal, parietal cortical areas and other motor cortical networks are activated. These activations may be involved in the reconstruction of neurons in the cerebral cortex. Growing evidence from clinical studies reveals that virtual reality training improves the neurological function of patients with spinal cord injury, cerebral palsy and other neurological impairments. These findings suggest that virtual reality training can acti- vate the cerebral cortex and improve the spatial orientation capacity of patients, thus facilitating the cortex to control balance and increase motion function.
文摘运用胜率标准差、赫芬达尔HHI指数、TOP K ranking等统计指标,对中美男子篮球职业联赛2008/2009—2003/2014赛季常规赛俱乐部之间竞争平衡进行对比分析。研究结果表明:在2008/2009—2003/2014常规赛赛季中,NBA职业联赛具有良好的平衡机制,平衡机制相对于CBA职业联赛较为完善。各测度指标进一步证明了NBA球队之间竞争实力更加平衡,比赛更具悬念和观赏性。我国CBA联赛与NBA联赛相比,球队之间竞争平衡机制不完善,导致球队之间竞赛水平差异较大,比赛缺乏观赏性。CBA联赛应借鉴NBA制衡机制的成功经验,细化选秀制度和转会制度,逐步完善后备人才的培养体系,使CBA职业篮球运动水平有显著的提高。
文摘随着电网结构的日益复杂,变电站关键设备的运行状态对电网安全稳定运行的影响逐渐增强。针对变电站复杂背景下多目标识别以及相似目标识别困难的问题,该文提出了一种基于注意力机制与特征平衡的YOLO-AFB(you only look once-attention and feature balance)网络。通过在Darknet-53网络中引入混合注意力加强对变电站相关目标的特征提取能力,在特征融合模块中加入反卷积来实现特征图的自适应上采样,提出特征平衡策略来缓解特征图语义信息差别,提高特征融合的质量。在含有9类目标的变电站数据集上进行测试,所提模型整体识别精度达到了83.02%,与经典目标检测网络对比,各类目标的检测精度均有大幅提升。同时互感器等相似目标的识别也得到明显改善,验证了特征平衡的策略可以很好地解决变电站中相似目标识别难的问题。
基金funded by a Senior Investigator Award(No.097726)from the Wellcome Trusta programme grant(No.C37030/A15101)from Cancer Research UK
文摘The AMP-activated protein kinase(AMPK)is a sensor of cellular energy status that is almost universally expressed in eukaryotic cells.While it appears to have evolved in single-celled eukaryotes to regulate energy balance in a cell-autonomous manner,during the evolution of multicellular animals its role has become adapted so that it also regulates energy balance at the whole body level,by responding to hormones that act primarily on the hypothalamus.AMPK monitors energy balance at the cellular level by sensing the ratios of AMP/ATP and ADP/ATP,and recent structural analyses of the AMPK heterotrimer that have provided insight into the complex mechanisms for these effects will be discussed.Given the central importance of energy balance in diseases that are major causes of morbidity or death in humans,such as type 2 diabetes,cancer and inflammatory disorders,there has been a major drive to develop pharmacological activators of AMPK.Many such activators have been described,and the various mechanisms by which these activate AMPK will be discussed.A particularly large class of AMPK activators are natural products of plants derived from traditional herbal medicines.While the mechanism by which most of these activate AMPK has not yet been addressed,I will argue that many of them may be defensive compounds produced by plants to deter infection by pathogens or grazing by insects or herbivores,and that many of them will turn out to be inhibitors of mitochondrial function.
