The National Strong Motion Observation Network System （NSMONS） of China is briefly introduced in this paper. The NSMONS consists of permanent free-field stations, special observation arrays, mobile observatories and...The National Strong Motion Observation Network System （NSMONS） of China is briefly introduced in this paper. The NSMONS consists of permanent free-field stations, special observation arrays, mobile observatories and a network management system. During the Wenchuan Earthquake, over 1,400 components of acceleration records were obtained from 460 permanent free-field stations and three arrays for topographical effect and structural response observation in the network system from the main shock, and over 20,000 components of acceleration records from strong aftershocks occurred before August 1, 2008 were also obtained by permanent free-field stations of the NSMONS and 59 mobile instruments quickly deployed after the main shock. The strong motion recordings from the main shock and strong aftershocks are summarized in this paper. In the ground motion recordings, there are over 560 components with peak ground acceleration （PGA） over 10 Gal, the largest being 957.7 Gal. The largest PGA recorded during the aftershock exceeds 300 Gal.展开更多
A high-density single nucleotide polymorphism （SNP） array is critically important for geneticists and molecu- lar breeders. With the accumulation of huge amounts of genomic re-sequencing data and available technolog...A high-density single nucleotide polymorphism （SNP） array is critically important for geneticists and molecu- lar breeders. With the accumulation of huge amounts of genomic re-sequencing data and available technologies for accurate SNP detection, it is possible to design high-density and high-quality rice SNP arrays. Here we report the devel- opment of a high-density rice SNP array and its utility. SNP probes were designed by screening more than 10 000 000 SNP loci extracted from the re-sequencing data of 801 rice varieties and an array named RiceSNP50 was produced on the Illumina Infinium platform. The array contained 51 478 evenly distributed markers, 68% of which were within genic regions. Several hundred rice plants with parent/F1 relationships were used to generate a high-quality cluster file for accurate SNP calling. Application tests showed that this array had high genotyping accuracy, and could be used for dif- ferent objectives. For example, a core collection of elite rice varieties was clustered with fine resolution. Genome-wide association studies （GWAS） analysis correctly identified a characterized QTL. Further, this array was successfully used for variety verification and trait introgression. As an accurate high-throughput genotyping tool, RiceSNP50 will play an important role in both functional genomics studies and molecular breeding.展开更多
针对气吸式棉花精密排种器输气管路结构复杂、能耗大以及排种单体只能实现单行播种等问题,采用阵列吸孔吸种、侧向气吹清种等方式,设计了一种气吸滚筒阵列式棉花精密排种器,确定了该排种器关键零部件的结构参数,建立了充种过程的力学模...针对气吸式棉花精密排种器输气管路结构复杂、能耗大以及排种单体只能实现单行播种等问题,采用阵列吸孔吸种、侧向气吹清种等方式,设计了一种气吸滚筒阵列式棉花精密排种器,确定了该排种器关键零部件的结构参数,建立了充种过程的力学模型。以棉花种子为播种对象,以滚筒转速、吸孔直径、气室负压为影响因子,以合格指数、漏播指数和重播指数为排种性能指标,进行二次旋转正交组合试验,建立各影响因子与排种性能指标之间的回归模型,分析了各因子对排种性能的影响规律。采用多目标优化方法,确定最佳参数组合:滚筒转速为15.5 r/min,吸孔直径为3.5 mm,气室负压为4.2 k Pa,此时排种器的合格指数为93.5%、漏播指数为2.0%、重播指数为4.5%。经试验验证,试验结果与优化结果基本一致,满足棉花精密播种的要求。在此基础上进行了排种适应性试验,试验对象为几何特性存在一定差异的新陆早48号、新陆早52号、新陆早60号3种棉花种子,结果表明:合格指数均大于92%,漏播指数均小于3%,重播指数均小于5%,说明该排种器对不同品种的棉花种子具有一定的排种适应性。展开更多
Gamma ray source detection above 30 TeV is an encouraging approach for finding galactic cosmic ray sources. All sky survey for gamma ray sources using wide field of view detector is essential for population accumulati...Gamma ray source detection above 30 TeV is an encouraging approach for finding galactic cosmic ray sources. All sky survey for gamma ray sources using wide field of view detector is essential for population accumulation for various types of sources above 100 GeV. In order to target those goals, a large air shower particle detector array of 1 km^2 （the LHAASO project） at 4300 m a.s.l, is proposed, By adding two MagicⅡ- type telescopes in the array as proposed, LHAASO will be enhanced in source morphologic investigation power. The proposed array will be utilized also for energy spectrum measurement for individual cosmic ray species above 30 TeV. By re-configuring the wide field of view telescopes into fluorescence light detector array, the aperture of the detector array can be enlarged to cover an energy region above 100 PeV where the second knee is located. Cosmic ray spectrum and composition will be measured in order to transfer an energy scale to ultra high energy cosmic ray experiments.展开更多
Laryngeal carcinoma is the most common malignancy among head and neck tu-mors. The purpose of this study is to find biomarkers for laryngeal carcinoma in patient blood serum using the Surface Enhanced Laser Desorption...Laryngeal carcinoma is the most common malignancy among head and neck tu-mors. The purpose of this study is to find biomarkers for laryngeal carcinoma in patient blood serum using the Surface Enhanced Laser Desorption/Ionization (SELDI) technique. Serum samples from 33 laryngeal carcinoma (12 cases of glottis, 18 of supraglottis and 3 of subglottis) patients and 31 age- and sex-matched healthy people were analyzed by SELDI-TOF on a Pro-teinChip reader, PBSII-C. Protein profiles were generated using WCX2 protein chips. Protein peak clustering and classification analyses were performed utilizing the Biomarker Wizard and Biomarker Pattern software packages, respectively. The results showed that sixteen peaks had significant difference between laryngeal cancer patients and healthy group, eight of which were up-regulated in the patient samples, and the others were down-regulated. Two protein peaks 8153 Da and 2035 Da were automatically chosen for the system training and development of a classification tree. The analysis yielded a correct percentage of 96.9% for patients and 96.7% for control. The results suggest that serum is a useful resource for the detection of specific bio-markers for laryngeal carcinoma. Proteinchip Array System was a useful tool for a high throughput screening of large-sized serum samples to discover potential biomarkers for carci-noma.展开更多
基金NSFC Under Grant No. 90715038MOST of China Under Grant No. 2006BAC13B02
文摘The National Strong Motion Observation Network System （NSMONS） of China is briefly introduced in this paper. The NSMONS consists of permanent free-field stations, special observation arrays, mobile observatories and a network management system. During the Wenchuan Earthquake, over 1,400 components of acceleration records were obtained from 460 permanent free-field stations and three arrays for topographical effect and structural response observation in the network system from the main shock, and over 20,000 components of acceleration records from strong aftershocks occurred before August 1, 2008 were also obtained by permanent free-field stations of the NSMONS and 59 mobile instruments quickly deployed after the main shock. The strong motion recordings from the main shock and strong aftershocks are summarized in this paper. In the ground motion recordings, there are over 560 components with peak ground acceleration （PGA） over 10 Gal, the largest being 957.7 Gal. The largest PGA recorded during the aftershock exceeds 300 Gal.
基金grants from the National High Technology Research and Development Program of China，the National Program on Key Basic Research Project of China，the National Natural Science Foundation of China，Guangdong Innovative Research Team Program，the Ministry of Agriculture of China
文摘A high-density single nucleotide polymorphism （SNP） array is critically important for geneticists and molecu- lar breeders. With the accumulation of huge amounts of genomic re-sequencing data and available technologies for accurate SNP detection, it is possible to design high-density and high-quality rice SNP arrays. Here we report the devel- opment of a high-density rice SNP array and its utility. SNP probes were designed by screening more than 10 000 000 SNP loci extracted from the re-sequencing data of 801 rice varieties and an array named RiceSNP50 was produced on the Illumina Infinium platform. The array contained 51 478 evenly distributed markers, 68% of which were within genic regions. Several hundred rice plants with parent/F1 relationships were used to generate a high-quality cluster file for accurate SNP calling. Application tests showed that this array had high genotyping accuracy, and could be used for dif- ferent objectives. For example, a core collection of elite rice varieties was clustered with fine resolution. Genome-wide association studies （GWAS） analysis correctly identified a characterized QTL. Further, this array was successfully used for variety verification and trait introgression. As an accurate high-throughput genotyping tool, RiceSNP50 will play an important role in both functional genomics studies and molecular breeding.
文摘针对气吸式棉花精密排种器输气管路结构复杂、能耗大以及排种单体只能实现单行播种等问题,采用阵列吸孔吸种、侧向气吹清种等方式,设计了一种气吸滚筒阵列式棉花精密排种器,确定了该排种器关键零部件的结构参数,建立了充种过程的力学模型。以棉花种子为播种对象,以滚筒转速、吸孔直径、气室负压为影响因子,以合格指数、漏播指数和重播指数为排种性能指标,进行二次旋转正交组合试验,建立各影响因子与排种性能指标之间的回归模型,分析了各因子对排种性能的影响规律。采用多目标优化方法,确定最佳参数组合:滚筒转速为15.5 r/min,吸孔直径为3.5 mm,气室负压为4.2 k Pa,此时排种器的合格指数为93.5%、漏播指数为2.0%、重播指数为4.5%。经试验验证,试验结果与优化结果基本一致,满足棉花精密播种的要求。在此基础上进行了排种适应性试验,试验对象为几何特性存在一定差异的新陆早48号、新陆早52号、新陆早60号3种棉花种子,结果表明:合格指数均大于92%,漏播指数均小于3%,重播指数均小于5%,说明该排种器对不同品种的棉花种子具有一定的排种适应性。
基金Supported by Knowledge Innovation Fund (U-526) of IHEP,China
文摘Gamma ray source detection above 30 TeV is an encouraging approach for finding galactic cosmic ray sources. All sky survey for gamma ray sources using wide field of view detector is essential for population accumulation for various types of sources above 100 GeV. In order to target those goals, a large air shower particle detector array of 1 km^2 （the LHAASO project） at 4300 m a.s.l, is proposed, By adding two MagicⅡ- type telescopes in the array as proposed, LHAASO will be enhanced in source morphologic investigation power. The proposed array will be utilized also for energy spectrum measurement for individual cosmic ray species above 30 TeV. By re-configuring the wide field of view telescopes into fluorescence light detector array, the aperture of the detector array can be enlarged to cover an energy region above 100 PeV where the second knee is located. Cosmic ray spectrum and composition will be measured in order to transfer an energy scale to ultra high energy cosmic ray experiments.
文摘Laryngeal carcinoma is the most common malignancy among head and neck tu-mors. The purpose of this study is to find biomarkers for laryngeal carcinoma in patient blood serum using the Surface Enhanced Laser Desorption/Ionization (SELDI) technique. Serum samples from 33 laryngeal carcinoma (12 cases of glottis, 18 of supraglottis and 3 of subglottis) patients and 31 age- and sex-matched healthy people were analyzed by SELDI-TOF on a Pro-teinChip reader, PBSII-C. Protein profiles were generated using WCX2 protein chips. Protein peak clustering and classification analyses were performed utilizing the Biomarker Wizard and Biomarker Pattern software packages, respectively. The results showed that sixteen peaks had significant difference between laryngeal cancer patients and healthy group, eight of which were up-regulated in the patient samples, and the others were down-regulated. Two protein peaks 8153 Da and 2035 Da were automatically chosen for the system training and development of a classification tree. The analysis yielded a correct percentage of 96.9% for patients and 96.7% for control. The results suggest that serum is a useful resource for the detection of specific bio-markers for laryngeal carcinoma. Proteinchip Array System was a useful tool for a high throughput screening of large-sized serum samples to discover potential biomarkers for carci-noma.
