AIM:To find out if by combining 2 ultrasound based elastographic methods:acoustic radiation force impulse(ARFI)elastography and transient elastography(TE),we can improve the prediction of fibrosis in patients with chr...AIM:To find out if by combining 2 ultrasound based elastographic methods:acoustic radiation force impulse(ARFI)elastography and transient elastography(TE),we can improve the prediction of fibrosis in patients with chronic hepatitis C.METHODS:Our study included 197 patients with chronic hepatitis C.In each patient,we performed,in the same session,liver stiffness(LS)measurements by means of TE and ARFI,respectively,and liver biopsy(LB),assessed according to the Metavir score.10 LS measurements were performed both by TE and ARFI;median values were calculated and expressed in kilopascals(kPa)and meters/second(m/s),respectively.Only TE and ARFI measurements with IQR<30%andSR≥60%were considered reliable.RESULTS:On LB 13(6.6%)patients had F0,32(16.2%) had F1,52(26.4%)had F2,47(23.9%)had F3,and 53(26.9%)had F4.A direct,strong correlation was found between TE measurements and fibrosis(r=0.741),between ARFI and fibrosis(r=0.730)and also between TE and ARFI(r=0.675).For predicting significant fibrosis(F≥2),for a cutoff of 6.7 kPa,TE had 77.5% sensitivity(Se)and 86.5%specificity(Sp)[area under the receiver operating characteristic curve(AUROC)0.87] and for a cutoff of 1.2 m/s,ARFI had 76.9%Se and 86.7%Sp(AUROC 0.84).For predicting cirrhosis(F=4),for a cutoff of 12.2 kPa,TE had 96.2%Se and 89.6% Sp(AUROC 0.97)and for a cutoff of 1.8 m/s,ARFI had 90.4%Se and 85.6%Sp(AUROC 0.91).When both elastographic methods were taken into consideration,for predicting significant fibrosis(F≥2),(TE≥6.7 kPa and ARFI≥1.2 m/s)we obtained 60.5%Se,93.3% Sp,96.8%positive predictive value(PPV),41.4%negative predictive value(NPV)and 68%accuracy,while for predicting cirrhosis(TE≥12.2 kPa and ARFI≥1.8 m/s) we obtained 84.9%Se,94.4%Sp,84.9%PPV,94.4% NPV and 91.8%accuracy.CONCLUSION:TE used in combination with ARFI is highly specific for predicting significant fibrosis;therefore when the two methods are concordant,liver biopsy can be avoided.展开更多
When measuring the surface subsidence of unstable areas such as railroad beds and large construction fields, it is not practical to always find stable positions to install measurement instruments. Yet installing those...When measuring the surface subsidence of unstable areas such as railroad beds and large construction fields, it is not practical to always find stable positions to install measurement instruments. Yet installing those instruments in unstable positions will cause measurement errors or even the complete failure of long-term subsidence surveillance. In this paper, the innovative concept and its method of "displacement-relay videometrics" are proposed. With the method, a double-headed camera is designed, and two constraints, the "fixation constraint" and the "homologous constraint", are established to construct the displacement-relay measurement equations, which can concurrently give the subsidence of the points to be measured and the positions where the cameras are fixed. The method and its measurement system are thus capable of automatically measuring the surface subsidence under the condition that the cameras are mounted on unstable locations over long durations. Therefore, the method has the broad prospect of undertaking automatic, long-term and continuous measurement for surface subsidence in engineering projects such as railroad beds, bridges and the ground beds of tall buildings. The proposed method opens a new area that cameras can be mounted on unstable platform to make high accuracy measurements, which is of great significance for applications.展开更多
Geologic surface approximation is profoundly affected by the presence, density and location of scattered geologic input data. Many studies have recognized the importance of utilizing varied sources of information when...Geologic surface approximation is profoundly affected by the presence, density and location of scattered geologic input data. Many studies have recognized the importance of utilizing varied sources of information when reconstructing a surface. This paper presents an improved geologic surface approximation method using a multiquadric function and borehole data. Additional information, i.e., inequality elevation and dip-strikes data extracted from outcrops or mining faces, is introduced in the form of physical constraints that control local changes in the estimated surface. Commonly accepted hypothesis states that geologic surfaces can be approximated to any desired degree of exactness by the summation of regular, mathematically defined, surfaces: in particular displaced quadric forms. The coefficients of the multiquadric functions are traditionally found by a least squares method. The addition of physical constraints in this work makes such an approach into a non-deterministic polynomial time problem. Hence we propose an objective function that represents the quality of the estimated surface and that includes the additional constraints by incorporation of a penalty function. Maximizing the smoothness of the estimated surface and its fitness to the additional constraints then allows the coefficients of the multiquadric function to be obtained by iterative methods. This method was implemented and demonstrated using data collected from the 81'st coal mining area of the Huaibei Coal Group.展开更多
Painleve integrability has been tested for （2＋1）D Boussinesq equation with disturbance term using the standard WTC approach after introducing the Kruskai＇s simplification. New breather solitary solutions depending...Painleve integrability has been tested for （2＋1）D Boussinesq equation with disturbance term using the standard WTC approach after introducing the Kruskai＇s simplification. New breather solitary solutions depending on constant equilibrium solution are obtained by using Extended Homoclinic Test Method. Moreover, the spatiotemporal feature of breather solitary wave is exhibited.展开更多
The C-C method was adopted to analyze the nonlinear characteristics of masseter electromyography （EMG） signals and the chaotic degree by the largest Lyapunov exponent （LLE） of different genders and sides. First, t...The C-C method was adopted to analyze the nonlinear characteristics of masseter electromyography （EMG） signals and the chaotic degree by the largest Lyapunov exponent （LLE） of different genders and sides. First, the embedding dimension and the delay time were obtained through this method, then the phase space was reconstructed to resume the chaotie attractor and determine the LLE. The result shows that the trajectory of attractor is denser than Chen＇s attractor, and the LLE is positive, which means that not only the signal has the character of chaos, but also the chaotic degree of masseter EMG is relatively high. According to the value of the LLE, the chaotic degree of men＇s masseter EMG is higher than that of women＇s; when the dentition is normal, the chaotic degree of two sides is almost the same. Then, a conclusion can be deduced that if the LLE of both sides are in great difference, the unilateral mastication is likely to exist, which means that the nonlinear characteristics of masseter EMG can be applied to predict the unilateral mastication.展开更多
考虑颗粒分布的不确定性,在排列熵计算过程中引入蒙特卡罗(Monte-Carlo,简称M-C)方法,用以表征排列混乱程度.为探究粗粒土剪切过程中排列熵的演化规律,以粗颗粒含量P5为指标,设立4种不同类型的粗粒土结构为研究对象,结合常法向应力下的...考虑颗粒分布的不确定性,在排列熵计算过程中引入蒙特卡罗(Monte-Carlo,简称M-C)方法,用以表征排列混乱程度.为探究粗粒土剪切过程中排列熵的演化规律,以粗颗粒含量P5为指标,设立4种不同类型的粗粒土结构为研究对象,结合常法向应力下的剪切试验(CNL)试验结果,运用Image Pro Plus等图像处理软件,同时通过室内剪切试验和数值模拟双向验证所揭示规律的可靠性.在206 kPa的法向应力下对4种结构的粗粒土进行剪切试验,以一组骨架密实结构数据为算例,利用多项式拟合试验结果,对比分析数值模拟和室内剪切试验排列熵变化结果.研究结果表明:剪切初期,粗粒土的排列熵随剪应力的增加呈先增大后减小的趋势,在达到峰值后随着剪应力的缓慢减小表现为先增大后减小的趋势.随着粗颗粒含量的升高,粗粒土结构发生变化,排列熵值增大,同时其排列分布的有序性受剪切作用的影响越大.展开更多
In order to differentiate regions, varieties, and parts of tobacco leaves, two pattern recognition methods through pattern classification modeling were developed based on the comprehensive information of ultraviolet-v...In order to differentiate regions, varieties, and parts of tobacco leaves, two pattern recognition methods through pattern classification modeling were developed based on the comprehensive information of ultraviolet-visible spectroscopy （UV-VIS） by employing one-way analysis of variance （ANOVA1） and wave range random combination （WRRC） technology from MATLAB. This proposed classification method has never been reported previously and the instrument and operation for this method is much more convenient and efficient than previous reported classification methods. The result of this paper demonstrated that the spectral features extracted by ANOVAI and WRRC methods could be used to differentiate tobacco leaves with different patterns. The ANOVAI method had a training recognition rate range of 75.00-87.50%,4 and a validation recognition rate range of 57.14-100%. The WRRC method had a training recognition rate range of 75.00-94.12% and a validation recognition rate range of 66.67-100%. The ANOVAI method is more convenient and efficient in model developing, while the WRRC method utilizes fewer model variables and is more robust.展开更多
文摘AIM:To find out if by combining 2 ultrasound based elastographic methods:acoustic radiation force impulse(ARFI)elastography and transient elastography(TE),we can improve the prediction of fibrosis in patients with chronic hepatitis C.METHODS:Our study included 197 patients with chronic hepatitis C.In each patient,we performed,in the same session,liver stiffness(LS)measurements by means of TE and ARFI,respectively,and liver biopsy(LB),assessed according to the Metavir score.10 LS measurements were performed both by TE and ARFI;median values were calculated and expressed in kilopascals(kPa)and meters/second(m/s),respectively.Only TE and ARFI measurements with IQR<30%andSR≥60%were considered reliable.RESULTS:On LB 13(6.6%)patients had F0,32(16.2%) had F1,52(26.4%)had F2,47(23.9%)had F3,and 53(26.9%)had F4.A direct,strong correlation was found between TE measurements and fibrosis(r=0.741),between ARFI and fibrosis(r=0.730)and also between TE and ARFI(r=0.675).For predicting significant fibrosis(F≥2),for a cutoff of 6.7 kPa,TE had 77.5% sensitivity(Se)and 86.5%specificity(Sp)[area under the receiver operating characteristic curve(AUROC)0.87] and for a cutoff of 1.2 m/s,ARFI had 76.9%Se and 86.7%Sp(AUROC 0.84).For predicting cirrhosis(F=4),for a cutoff of 12.2 kPa,TE had 96.2%Se and 89.6% Sp(AUROC 0.97)and for a cutoff of 1.8 m/s,ARFI had 90.4%Se and 85.6%Sp(AUROC 0.91).When both elastographic methods were taken into consideration,for predicting significant fibrosis(F≥2),(TE≥6.7 kPa and ARFI≥1.2 m/s)we obtained 60.5%Se,93.3% Sp,96.8%positive predictive value(PPV),41.4%negative predictive value(NPV)and 68%accuracy,while for predicting cirrhosis(TE≥12.2 kPa and ARFI≥1.8 m/s) we obtained 84.9%Se,94.4%Sp,84.9%PPV,94.4% NPV and 91.8%accuracy.CONCLUSION:TE used in combination with ARFI is highly specific for predicting significant fibrosis;therefore when the two methods are concordant,liver biopsy can be avoided.
基金supported by the National Natural Science Foundation of China(Grant Nos.11332012 and 11172323)
文摘When measuring the surface subsidence of unstable areas such as railroad beds and large construction fields, it is not practical to always find stable positions to install measurement instruments. Yet installing those instruments in unstable positions will cause measurement errors or even the complete failure of long-term subsidence surveillance. In this paper, the innovative concept and its method of "displacement-relay videometrics" are proposed. With the method, a double-headed camera is designed, and two constraints, the "fixation constraint" and the "homologous constraint", are established to construct the displacement-relay measurement equations, which can concurrently give the subsidence of the points to be measured and the positions where the cameras are fixed. The method and its measurement system are thus capable of automatically measuring the surface subsidence under the condition that the cameras are mounted on unstable locations over long durations. Therefore, the method has the broad prospect of undertaking automatic, long-term and continuous measurement for surface subsidence in engineering projects such as railroad beds, bridges and the ground beds of tall buildings. The proposed method opens a new area that cameras can be mounted on unstable platform to make high accuracy measurements, which is of great significance for applications.
基金provided by the National Science and Technology Major Project of China (Nos.2009ZX05039-004 and 2009ZX 05039-002)the National Natural Science Foundation of China (Nos.40771167 and 70621001)
文摘Geologic surface approximation is profoundly affected by the presence, density and location of scattered geologic input data. Many studies have recognized the importance of utilizing varied sources of information when reconstructing a surface. This paper presents an improved geologic surface approximation method using a multiquadric function and borehole data. Additional information, i.e., inequality elevation and dip-strikes data extracted from outcrops or mining faces, is introduced in the form of physical constraints that control local changes in the estimated surface. Commonly accepted hypothesis states that geologic surfaces can be approximated to any desired degree of exactness by the summation of regular, mathematically defined, surfaces: in particular displaced quadric forms. The coefficients of the multiquadric functions are traditionally found by a least squares method. The addition of physical constraints in this work makes such an approach into a non-deterministic polynomial time problem. Hence we propose an objective function that represents the quality of the estimated surface and that includes the additional constraints by incorporation of a penalty function. Maximizing the smoothness of the estimated surface and its fitness to the additional constraints then allows the coefficients of the multiquadric function to be obtained by iterative methods. This method was implemented and demonstrated using data collected from the 81'st coal mining area of the Huaibei Coal Group.
基金Supported by National Natural Science Foundation of China under Grant Nos. 11061028, 11261049, Yunnan Natural Science Foundation under Grant Nos. 2010CD086 and 2011Y012 and Qujing Normal University Natural Science Foundation under Grant Nos. 2009ZD002 and 2012QN016
文摘Painleve integrability has been tested for （2＋1）D Boussinesq equation with disturbance term using the standard WTC approach after introducing the Kruskai＇s simplification. New breather solitary solutions depending on constant equilibrium solution are obtained by using Extended Homoclinic Test Method. Moreover, the spatiotemporal feature of breather solitary wave is exhibited.
文摘The C-C method was adopted to analyze the nonlinear characteristics of masseter electromyography （EMG） signals and the chaotic degree by the largest Lyapunov exponent （LLE） of different genders and sides. First, the embedding dimension and the delay time were obtained through this method, then the phase space was reconstructed to resume the chaotie attractor and determine the LLE. The result shows that the trajectory of attractor is denser than Chen＇s attractor, and the LLE is positive, which means that not only the signal has the character of chaos, but also the chaotic degree of masseter EMG is relatively high. According to the value of the LLE, the chaotic degree of men＇s masseter EMG is higher than that of women＇s; when the dentition is normal, the chaotic degree of two sides is almost the same. Then, a conclusion can be deduced that if the LLE of both sides are in great difference, the unilateral mastication is likely to exist, which means that the nonlinear characteristics of masseter EMG can be applied to predict the unilateral mastication.
文摘考虑颗粒分布的不确定性,在排列熵计算过程中引入蒙特卡罗(Monte-Carlo,简称M-C)方法,用以表征排列混乱程度.为探究粗粒土剪切过程中排列熵的演化规律,以粗颗粒含量P5为指标,设立4种不同类型的粗粒土结构为研究对象,结合常法向应力下的剪切试验(CNL)试验结果,运用Image Pro Plus等图像处理软件,同时通过室内剪切试验和数值模拟双向验证所揭示规律的可靠性.在206 kPa的法向应力下对4种结构的粗粒土进行剪切试验,以一组骨架密实结构数据为算例,利用多项式拟合试验结果,对比分析数值模拟和室内剪切试验排列熵变化结果.研究结果表明:剪切初期,粗粒土的排列熵随剪应力的增加呈先增大后减小的趋势,在达到峰值后随着剪应力的缓慢减小表现为先增大后减小的趋势.随着粗颗粒含量的升高,粗粒土结构发生变化,排列熵值增大,同时其排列分布的有序性受剪切作用的影响越大.
文摘In order to differentiate regions, varieties, and parts of tobacco leaves, two pattern recognition methods through pattern classification modeling were developed based on the comprehensive information of ultraviolet-visible spectroscopy （UV-VIS） by employing one-way analysis of variance （ANOVA1） and wave range random combination （WRRC） technology from MATLAB. This proposed classification method has never been reported previously and the instrument and operation for this method is much more convenient and efficient than previous reported classification methods. The result of this paper demonstrated that the spectral features extracted by ANOVAI and WRRC methods could be used to differentiate tobacco leaves with different patterns. The ANOVAI method had a training recognition rate range of 75.00-87.50%,4 and a validation recognition rate range of 57.14-100%. The WRRC method had a training recognition rate range of 75.00-94.12% and a validation recognition rate range of 66.67-100%. The ANOVAI method is more convenient and efficient in model developing, while the WRRC method utilizes fewer model variables and is more robust.
