目的探讨CT血管造影(CTA)与多普勒超声(DUS)检查在下肢动脉硬化性闭塞症(ASO)中的诊断效能。方法选取我院经数字减影血管造影(DSA)检查并接受腔内血管成形术治疗的80例ASO患者。以DSA作为金标准,对比患者术前CTA及DUS诊断ASO的效能及一...目的探讨CT血管造影(CTA)与多普勒超声(DUS)检查在下肢动脉硬化性闭塞症(ASO)中的诊断效能。方法选取我院经数字减影血管造影(DSA)检查并接受腔内血管成形术治疗的80例ASO患者。以DSA作为金标准,对比患者术前CTA及DUS诊断ASO的效能及一致性。结果CTA对全段下肢动脉及髂动脉段≥50%血管狭窄及闭塞的检出率分别较DUS高4.89%(P=0.002)和2.29%(P=0.007)。CTA对下肢全段≥50%血管狭窄及腘上动脉段管腔闭塞的诊断效能及一致性均高于DUS(敏感性:81.47%~96.84%vs 80.35%~89.66%;特异性82.39%~90.75%vs 82.16%~87.25%;Kappa值:0.82~0.98 vs 0.79~0.94),而对腘下动脉段血管闭塞的评估表现不及DUS(敏感性:77.83%vs 78.49%;特异性:72.15%vs 79.28%;Kappa值:0.72 vs 0.76)。结论CTA对ASO患者的血管评估效能总体优于DUS,而对于腘下动脉段血管重度狭窄及闭塞仍需联合DUS综合评估,以制定最佳临床治疗方案。展开更多
Objective To study of the effectiveness of using autologous mononuclear fraction of bone marrow for the treatment of chronic limb ischemia. Methods Results of autologous mononuclear fraction of bone marrow in 90 labor...Objective To study of the effectiveness of using autologous mononuclear fraction of bone marrow for the treatment of chronic limb ischemia. Methods Results of autologous mononuclear fraction of bone marrow in 90 laboratory Wistar rats on a background of creating chronic limb ischemia was presented. Sampling was carried out from the bone marrow of the femur of the animal. The mononuclear fraction of bone marrow autologous 4 × 106 cells in a volume of 200 microliter were injected into the ischemic limb of the two points,in each of which 100 microliter:(1)Paravessel directly below the inguinal ligament at the level of the sacroiliac joint in the area of the anatomical location of collaterals in the projection of the internal iliac artery and its branches;(2)Intramuscularly in gastrocnemius muscle anterior-lateral surface of the middle third of the leg. Results In the experimental group of rats treated with autologous mononuclear fraction of bone marrow,the level of microcirculation compared with the intact group of animals on day 21 was higher than 6. 1% by day 28% ~ 31. 2%; compared with the control group-day 10 increased by 111% at day 21,85. 7% on day 28% ~ 97%. Conclusion Proposed method of treating pathogenically justified and can be recommended for use in clinical practice in the treatment of patients with chronic obliterating diseases of lower limb arteries.展开更多
文摘目的探讨CT血管造影(CTA)与多普勒超声(DUS)检查在下肢动脉硬化性闭塞症(ASO)中的诊断效能。方法选取我院经数字减影血管造影(DSA)检查并接受腔内血管成形术治疗的80例ASO患者。以DSA作为金标准,对比患者术前CTA及DUS诊断ASO的效能及一致性。结果CTA对全段下肢动脉及髂动脉段≥50%血管狭窄及闭塞的检出率分别较DUS高4.89%(P=0.002)和2.29%(P=0.007)。CTA对下肢全段≥50%血管狭窄及腘上动脉段管腔闭塞的诊断效能及一致性均高于DUS(敏感性:81.47%~96.84%vs 80.35%~89.66%;特异性82.39%~90.75%vs 82.16%~87.25%;Kappa值:0.82~0.98 vs 0.79~0.94),而对腘下动脉段血管闭塞的评估表现不及DUS(敏感性:77.83%vs 78.49%;特异性:72.15%vs 79.28%;Kappa值:0.72 vs 0.76)。结论CTA对ASO患者的血管评估效能总体优于DUS,而对于腘下动脉段血管重度狭窄及闭塞仍需联合DUS综合评估,以制定最佳临床治疗方案。
文摘Objective To study of the effectiveness of using autologous mononuclear fraction of bone marrow for the treatment of chronic limb ischemia. Methods Results of autologous mononuclear fraction of bone marrow in 90 laboratory Wistar rats on a background of creating chronic limb ischemia was presented. Sampling was carried out from the bone marrow of the femur of the animal. The mononuclear fraction of bone marrow autologous 4 × 106 cells in a volume of 200 microliter were injected into the ischemic limb of the two points,in each of which 100 microliter:(1)Paravessel directly below the inguinal ligament at the level of the sacroiliac joint in the area of the anatomical location of collaterals in the projection of the internal iliac artery and its branches;(2)Intramuscularly in gastrocnemius muscle anterior-lateral surface of the middle third of the leg. Results In the experimental group of rats treated with autologous mononuclear fraction of bone marrow,the level of microcirculation compared with the intact group of animals on day 21 was higher than 6. 1% by day 28% ~ 31. 2%; compared with the control group-day 10 increased by 111% at day 21,85. 7% on day 28% ~ 97%. Conclusion Proposed method of treating pathogenically justified and can be recommended for use in clinical practice in the treatment of patients with chronic obliterating diseases of lower limb arteries.
