Ascariasis can be found in temperate and tropical areas but is more prevalent in most of the inter tropical zone due to local socio-economic conditions.Loeffler’s syndrome,also known as eosinophilic pulmonary syndrom...Ascariasis can be found in temperate and tropical areas but is more prevalent in most of the inter tropical zone due to local socio-economic conditions.Loeffler’s syndrome,also known as eosinophilic pulmonary syndrome is due to the trans-alveolar migration of ascaris larvae about 2 weeks after initial oral contamination.In this article, the case of a 10-year old child referred by his pediatrician for isolated eosinophilia,who was finally diagnosed with to have Loeffler’s syndrome is presented and discussed.展开更多
Loeffier endocarditis is clinically presented as restrictive cardiomyopathy, which is the least common of the three major categories of cardiomyopathic disorders.1 The endomyocardial fibrosis was considered as its mai...Loeffier endocarditis is clinically presented as restrictive cardiomyopathy, which is the least common of the three major categories of cardiomyopathic disorders.1 The endomyocardial fibrosis was considered as its main pathophysiologic changes.24 Generally speaking, the characteristics include thickening of the apex and inflow tracts of one or both ventricles, and the papillary muscle and chordae tendineae also can be involved in some cases.展开更多
BACKGROUND Eosinophilic granulomatosis with polyangiitis(EGPA),formerly known as Churg-Strauss syndrome,is a rare form of anti-neutrophil cytoplasmic antibodyassociated vasculitis characterized by asthma,vasculitis,an...BACKGROUND Eosinophilic granulomatosis with polyangiitis(EGPA),formerly known as Churg-Strauss syndrome,is a rare form of anti-neutrophil cytoplasmic antibodyassociated vasculitis characterized by asthma,vasculitis,and eosinophilia.CASE SUMMARY We report an atypical case of EGPA in a 20-year-old female patient.Unlike previously reported cases of EGPA,this patient’s initial symptom was asthma associated with a respiratory infection.This was followed by Loeffler endocarditis and cardiac insufficiency.She received treatment with methylprednisolone sodium succinate,low molecular weight heparin,recombinant human brain natriuretic peptide,furosemide,cefoperazone sodium/sulbactam sodium,and acyclovir.Despite prophylactic anticoagulation,she developed a large right ventricular thrombus.EGPA diagnosis was confirmed based on ancillary test results and specialty consultations.Subsequent treatment included mycophenolate mofetil.Her overall condition improved significantly after treatment,as evidenced by decreased peripheral blood eosinophils and cardiac markers.She was discharged after 17 d.Her most recent follow-up showed normal peripheral blood eosinophil levels,restored cardiac function,and a reduced cardiac mural thrombus size.CONCLUSION This case illustrates the swift progression of EGPA and underscores the significance of early detection and immediate intervention to ensure a favorable prognosis.展开更多
文摘Ascariasis can be found in temperate and tropical areas but is more prevalent in most of the inter tropical zone due to local socio-economic conditions.Loeffler’s syndrome,also known as eosinophilic pulmonary syndrome is due to the trans-alveolar migration of ascaris larvae about 2 weeks after initial oral contamination.In this article, the case of a 10-year old child referred by his pediatrician for isolated eosinophilia,who was finally diagnosed with to have Loeffler’s syndrome is presented and discussed.
基金This study was supported by a grant from the National Natural Science Foundation of China （No. 30470520）.
文摘Loeffier endocarditis is clinically presented as restrictive cardiomyopathy, which is the least common of the three major categories of cardiomyopathic disorders.1 The endomyocardial fibrosis was considered as its main pathophysiologic changes.24 Generally speaking, the characteristics include thickening of the apex and inflow tracts of one or both ventricles, and the papillary muscle and chordae tendineae also can be involved in some cases.
基金Supported by the 2020 National Natural Science Foundation Cultivation Project of Guizhou Medical University Affiliated Hospital,No.gyfynsfc[2020]-14.
文摘BACKGROUND Eosinophilic granulomatosis with polyangiitis(EGPA),formerly known as Churg-Strauss syndrome,is a rare form of anti-neutrophil cytoplasmic antibodyassociated vasculitis characterized by asthma,vasculitis,and eosinophilia.CASE SUMMARY We report an atypical case of EGPA in a 20-year-old female patient.Unlike previously reported cases of EGPA,this patient’s initial symptom was asthma associated with a respiratory infection.This was followed by Loeffler endocarditis and cardiac insufficiency.She received treatment with methylprednisolone sodium succinate,low molecular weight heparin,recombinant human brain natriuretic peptide,furosemide,cefoperazone sodium/sulbactam sodium,and acyclovir.Despite prophylactic anticoagulation,she developed a large right ventricular thrombus.EGPA diagnosis was confirmed based on ancillary test results and specialty consultations.Subsequent treatment included mycophenolate mofetil.Her overall condition improved significantly after treatment,as evidenced by decreased peripheral blood eosinophils and cardiac markers.She was discharged after 17 d.Her most recent follow-up showed normal peripheral blood eosinophil levels,restored cardiac function,and a reduced cardiac mural thrombus size.CONCLUSION This case illustrates the swift progression of EGPA and underscores the significance of early detection and immediate intervention to ensure a favorable prognosis.
