A review was carried out in Medline,LILACS and the Cochrane Library.Our database search strategy included the following terms: "hydatid cyst","liver","management","meta-analysis"...A review was carried out in Medline,LILACS and the Cochrane Library.Our database search strategy included the following terms: "hydatid cyst","liver","management","meta-analysis" and "randomized controlled trial".No language limits were used in the literature search.The latest electronic search date was the 7th of January 2014.Inclusion and exclusion criteria: all relevant studies on the assessment of therapeutic methods for hydatid cysts of the liver were considered for analysis.Information from editorials,letters to publishers,low quality review articles and studies done on animals were excluded from analysis.Additionally,well-structured abstracts from relevant articles were selected and accepted for analysis.Standardized forms were designed for data extraction; two investigators entered the data on patient demographics,methodology,recurrence of HC,mean cyst size and number of cysts per group.Four hundred and fourteen articles were identified using the previously described search strategy.After applying the inclusion and exclusion criteria detailed above,57 articles were selected for final analysis: one meta-analysis,9 randomized clinical trials,5 non-randomized comparative prospective studies,7 non-comparative prospective studies,and 34 retrospective studies(12 comparative and 22 noncomparative).Our results indicate that antihelminthic treatment alone is not the ideal treatment for liver hydatid cysts.More studies in the literature support the effectiveness of radical treatment compared with conservative treatment.Conservative surgery with omentoplasty is effective in preventing postoperative complications.A laparoscopic approach is safe in some situations.Percutaneous drainage with albendazole therapy is a safe and effective alternative treatment for hydatid cysts of the liver.Radical surgery with preand post-operative administration of albendazole is the best treatment option for liver hydatid cysts due to low recurrence and complication rates.展开更多
Cystic formations within the liver are a frequent finding among populations.Besides the common cystic lesions,like simple liver cysts,rare cystic liver lesions like cystadenocarcinoma should also be considered in the ...Cystic formations within the liver are a frequent finding among populations.Besides the common cystic lesions,like simple liver cysts,rare cystic liver lesions like cystadenocarcinoma should also be considered in the differential diagnosis.Thorough knowledge of each entity’s nature and course are key elements to successful treatment.Detailed search in PubMed,Cochrane Database,and international published literature regarding rare cystic liver lesions was carried out.In our research are included not only primary rare lesions like cystadenoma,hydatid cyst,and polycystic liver disease,but also secondary ones like metastasis from gastrointestinal stromal tumors lesions.Up-to date knowledge regarding diagnosis and management of rare cystic liver lesions is provided.A diagnostic and therapeutic algorithm is also proposed.The need for a multidisciplinary approach by a team including radiologists and surgeons familiar with liver cystic entities,diagnostic tools,and treatment modalities is stressed.Patients with cystic liver lesions must be carefully evaluated by a multidisciplinary team,in order to receive the most appropriate treatment,since many cystic liver lesions have a malignant potential and evolution.展开更多
目的探讨超声内镜(EUS)引导下穿刺抽吸联合硬化剂注射术对肝囊肿患者炎症因子的影响。方法2020年6月-2022年6月安阳市第三人民医院收治的肝囊肿患者90例,随机数字表法分为对照组和观察组各45例,依次行硬化剂注射术或者EUS引导下穿刺抽...目的探讨超声内镜(EUS)引导下穿刺抽吸联合硬化剂注射术对肝囊肿患者炎症因子的影响。方法2020年6月-2022年6月安阳市第三人民医院收治的肝囊肿患者90例,随机数字表法分为对照组和观察组各45例,依次行硬化剂注射术或者EUS引导下穿刺抽吸联合硬化剂注射术,观察48周。比较两组治疗前及治疗后7 d血生化指标及炎因子水平,分析两组治疗后12周总有效率及不良反应发生率,并观察两组治疗后48周肝囊肿复发率。结果观察组治疗后12周末总有效率为95.56%,高于对照组的82.22%(P<0.05)。两组治疗后7 d ALT、AST、ALP及TBil无显著差异(P>0.05)。观察组治疗后7 d血清CRP、TNF-α和IL-1β水平分别为(53.83±6.24)mg/L、(260.80±18.40)ng/L和(91.04±5.10)ng/L,显著低于对照组[(56.67±5.96)mg/L、(268.92±16.93)ng/L和(93.22±4.87)ng/L,P<0.05]。观察组不良反应发生率为2.22%,低于对照组的17.78%(P<0.05)。观察组治疗后48周末肝囊肿复发率为2.27%,低于对照组的17.95%(P<0.05)。结论相较于硬化剂注射术,EUS引导下穿刺抽吸联合硬化剂注射术治疗肝囊肿临床疗效更为确切,可缓解机体炎症反应,减少并发症及复发,对患者肝功能并无明显影响。展开更多
Laparoscopic procedure as a minimally invasive surgery had been introduced into many abdominal surgery. Smaller incisions of the abdominal wall reduce postoperative pain and the risk of wound complications, and provid...Laparoscopic procedure as a minimally invasive surgery had been introduced into many abdominal surgery. Smaller incisions of the abdominal wall reduce postoperative pain and the risk of wound complications, and provide an excellent cosmetic result compared with open surgery. Flexible endoscope-based transgastric, transcolonic, or transvaginal surgery for abdominal exploration, cholecystectomy, appendectomy, and tubal ligation may further reduce the surgical invasion.展开更多
文摘A review was carried out in Medline,LILACS and the Cochrane Library.Our database search strategy included the following terms: "hydatid cyst","liver","management","meta-analysis" and "randomized controlled trial".No language limits were used in the literature search.The latest electronic search date was the 7th of January 2014.Inclusion and exclusion criteria: all relevant studies on the assessment of therapeutic methods for hydatid cysts of the liver were considered for analysis.Information from editorials,letters to publishers,low quality review articles and studies done on animals were excluded from analysis.Additionally,well-structured abstracts from relevant articles were selected and accepted for analysis.Standardized forms were designed for data extraction; two investigators entered the data on patient demographics,methodology,recurrence of HC,mean cyst size and number of cysts per group.Four hundred and fourteen articles were identified using the previously described search strategy.After applying the inclusion and exclusion criteria detailed above,57 articles were selected for final analysis: one meta-analysis,9 randomized clinical trials,5 non-randomized comparative prospective studies,7 non-comparative prospective studies,and 34 retrospective studies(12 comparative and 22 noncomparative).Our results indicate that antihelminthic treatment alone is not the ideal treatment for liver hydatid cysts.More studies in the literature support the effectiveness of radical treatment compared with conservative treatment.Conservative surgery with omentoplasty is effective in preventing postoperative complications.A laparoscopic approach is safe in some situations.Percutaneous drainage with albendazole therapy is a safe and effective alternative treatment for hydatid cysts of the liver.Radical surgery with preand post-operative administration of albendazole is the best treatment option for liver hydatid cysts due to low recurrence and complication rates.
文摘Cystic formations within the liver are a frequent finding among populations.Besides the common cystic lesions,like simple liver cysts,rare cystic liver lesions like cystadenocarcinoma should also be considered in the differential diagnosis.Thorough knowledge of each entity’s nature and course are key elements to successful treatment.Detailed search in PubMed,Cochrane Database,and international published literature regarding rare cystic liver lesions was carried out.In our research are included not only primary rare lesions like cystadenoma,hydatid cyst,and polycystic liver disease,but also secondary ones like metastasis from gastrointestinal stromal tumors lesions.Up-to date knowledge regarding diagnosis and management of rare cystic liver lesions is provided.A diagnostic and therapeutic algorithm is also proposed.The need for a multidisciplinary approach by a team including radiologists and surgeons familiar with liver cystic entities,diagnostic tools,and treatment modalities is stressed.Patients with cystic liver lesions must be carefully evaluated by a multidisciplinary team,in order to receive the most appropriate treatment,since many cystic liver lesions have a malignant potential and evolution.
文摘目的探讨超声内镜(EUS)引导下穿刺抽吸联合硬化剂注射术对肝囊肿患者炎症因子的影响。方法2020年6月-2022年6月安阳市第三人民医院收治的肝囊肿患者90例,随机数字表法分为对照组和观察组各45例,依次行硬化剂注射术或者EUS引导下穿刺抽吸联合硬化剂注射术,观察48周。比较两组治疗前及治疗后7 d血生化指标及炎因子水平,分析两组治疗后12周总有效率及不良反应发生率,并观察两组治疗后48周肝囊肿复发率。结果观察组治疗后12周末总有效率为95.56%,高于对照组的82.22%(P<0.05)。两组治疗后7 d ALT、AST、ALP及TBil无显著差异(P>0.05)。观察组治疗后7 d血清CRP、TNF-α和IL-1β水平分别为(53.83±6.24)mg/L、(260.80±18.40)ng/L和(91.04±5.10)ng/L,显著低于对照组[(56.67±5.96)mg/L、(268.92±16.93)ng/L和(93.22±4.87)ng/L,P<0.05]。观察组不良反应发生率为2.22%,低于对照组的17.78%(P<0.05)。观察组治疗后48周末肝囊肿复发率为2.27%,低于对照组的17.95%(P<0.05)。结论相较于硬化剂注射术,EUS引导下穿刺抽吸联合硬化剂注射术治疗肝囊肿临床疗效更为确切,可缓解机体炎症反应,减少并发症及复发,对患者肝功能并无明显影响。
文摘Laparoscopic procedure as a minimally invasive surgery had been introduced into many abdominal surgery. Smaller incisions of the abdominal wall reduce postoperative pain and the risk of wound complications, and provide an excellent cosmetic result compared with open surgery. Flexible endoscope-based transgastric, transcolonic, or transvaginal surgery for abdominal exploration, cholecystectomy, appendectomy, and tubal ligation may further reduce the surgical invasion.
