Background: To examine the differences in prevalence of respiratory distress syndrome, early-onset sepsis and jaundice, between late preterm infants versus term infants in Ecuadorian newborns. Methods: Study design: E...Background: To examine the differences in prevalence of respiratory distress syndrome, early-onset sepsis and jaundice, between late preterm infants versus term infants in Ecuadorian newborns. Methods: Study design: Epidemiological, observational, and cross-sectional, with two cohorts of patients. Settings: IESS Quito Sur Hospital at Quito, Ecuador, from February to April of 2020. Participants: This study included 204 newborns, 102 preterm infants, 102 term infants. Results: There are significant differences between late preterm infants and term infants, with a p-value of 0.000 in the prevalence of early sepsis, 70.59% vs. 35.29%. In respiratory distress syndrome between late and term premature infants, significant differences were observed with a p-value of 0.000, the proportion being 55.58% vs. 24.51% respectively. The prevalence of jaundice is higher in term infants with a p value of 0.002, 72.55%, versus 51.96% in late preterm infants, and the mean value of bilirubins in mg/dL was higher in term infants 14.32 versus 12.33 in late preterm infants;this difference is statistically significant with a p value of 0.004. Admission to the NICU is more frequent in late preterm infants with a p-value of 0.000, being 42.16% for late preterm infants vs. 7.84% in term infants;the mean of the hospital days with p-value 0.005, was higher in late preterm infants 4.97 days vs. 3.55 days for term newborns. Conclusion: Due to the conditions of their immaturity, late preterm infants are 2.86 times more likely to present early sepsis than full-term newborns. It is shown that late preterm infants are 2.69 times more likely to have respiratory distress syndrome compared to term infants, therefore, late preterm infants have a longer hospital stay of 4.97 days versus 3.55 days in term infants. Jaundice and mean bilirubin levels are higher in term infants due to blood group incompatibility and insufficient breastfeeding.展开更多
Purpose: To investigate the relationship between preterm delivery and developmental outcomes in children born at 34 - 36 weeks of gestation (late preterm period). Methods: This study reviewed the cases of singleton la...Purpose: To investigate the relationship between preterm delivery and developmental outcomes in children born at 34 - 36 weeks of gestation (late preterm period). Methods: This study reviewed the cases of singleton late preterm children and full-term (38 - 40 weeks of gestation) children born at Showa University Hospital. The developmental outcomes at 3 years of age were assessed based on the results of questionnaires sent to the families by mail. In addition, the incidence of developmental delays was compared between the late preterm and full-term children. In the full-term control group, perinatal characteristics (neonatal gender, Apgar score, Cesarean delivery, birth weight < 10th percentile, birth weight < 3rd percentile) were matched with those of the late preterm cases. We compared categorical variables using Fisher’s exact test. For variables with a non-normal distribution, Welch’s t-test was applied. A p-value of <0.05 was considered to be statistically significant. Results: The rate of return of the questionnaires was 25.9% (121) among the cases and 25.8% (163) among the controls. The frequency of developmental delays was 6.6% among the cases, compared with 4.3% among the controls. Conclusions: Matching the perinatal characteristics of the subjects, the frequency of developmental delays was similar between the two groups.展开更多
目的探讨晚期早产儿呼吸系统疾病患病的临床特点。方法选取2009年1月至2010年12月在我院产科出生的新生儿,其中晚期早产儿(胎龄34～36+6周)630例,足月儿4401例,早期早产儿(胎龄≤33+6周)328例。其中患呼吸系统疾病者包括晚期早产儿84例...目的探讨晚期早产儿呼吸系统疾病患病的临床特点。方法选取2009年1月至2010年12月在我院产科出生的新生儿,其中晚期早产儿(胎龄34～36+6周)630例,足月儿4401例,早期早产儿(胎龄≤33+6周)328例。其中患呼吸系统疾病者包括晚期早产儿84例,足月儿135例,早期早产儿182例。比较3组新生儿呼吸系统疾病发病情况、临床特点及危重程度。结果 (1)晚期早产儿组呼吸系统疾病发生率、病死率及危重症比例均高于足月儿组,而低于早期早产儿组(P<0.01)。(2)晚期早产儿组呼吸困难起病时间早于足月儿组,晚于早期早产儿组(P<0.01);呼吸增快百分比较其他两组高,而三凹征百分比较低(P<0.05);晚期早产儿组需氧疗及机械通气的比例均明显高于足月儿组,而低于早期早产儿组(P<0.05)。(3)多元线性回归分析发现血氧分压降低、红细胞压积减低、血pH值减低、呼吸减慢、动脉血氧饱和度减低、动脉收缩压减低、5 min Apgar评分减低、胎龄较小、血尿素氮增高、心率增快、呼吸增快是新生儿呼吸系统疾病危重症的影响因素。结论晚期早产儿比足月儿更容易出现呼吸系统疾病,危重程度较重,需加强呼吸支持。晚期早产儿呼吸困难多表现为呼吸增快,起病时间早于足月儿而晚于早期早产儿。对于晚期早产儿,如发现呼吸困难、心率、血压异常及多系统受累表现,常提示其病情危重,应积极治疗。展开更多
文摘Background: To examine the differences in prevalence of respiratory distress syndrome, early-onset sepsis and jaundice, between late preterm infants versus term infants in Ecuadorian newborns. Methods: Study design: Epidemiological, observational, and cross-sectional, with two cohorts of patients. Settings: IESS Quito Sur Hospital at Quito, Ecuador, from February to April of 2020. Participants: This study included 204 newborns, 102 preterm infants, 102 term infants. Results: There are significant differences between late preterm infants and term infants, with a p-value of 0.000 in the prevalence of early sepsis, 70.59% vs. 35.29%. In respiratory distress syndrome between late and term premature infants, significant differences were observed with a p-value of 0.000, the proportion being 55.58% vs. 24.51% respectively. The prevalence of jaundice is higher in term infants with a p value of 0.002, 72.55%, versus 51.96% in late preterm infants, and the mean value of bilirubins in mg/dL was higher in term infants 14.32 versus 12.33 in late preterm infants;this difference is statistically significant with a p value of 0.004. Admission to the NICU is more frequent in late preterm infants with a p-value of 0.000, being 42.16% for late preterm infants vs. 7.84% in term infants;the mean of the hospital days with p-value 0.005, was higher in late preterm infants 4.97 days vs. 3.55 days for term newborns. Conclusion: Due to the conditions of their immaturity, late preterm infants are 2.86 times more likely to present early sepsis than full-term newborns. It is shown that late preterm infants are 2.69 times more likely to have respiratory distress syndrome compared to term infants, therefore, late preterm infants have a longer hospital stay of 4.97 days versus 3.55 days in term infants. Jaundice and mean bilirubin levels are higher in term infants due to blood group incompatibility and insufficient breastfeeding.
文摘Purpose: To investigate the relationship between preterm delivery and developmental outcomes in children born at 34 - 36 weeks of gestation (late preterm period). Methods: This study reviewed the cases of singleton late preterm children and full-term (38 - 40 weeks of gestation) children born at Showa University Hospital. The developmental outcomes at 3 years of age were assessed based on the results of questionnaires sent to the families by mail. In addition, the incidence of developmental delays was compared between the late preterm and full-term children. In the full-term control group, perinatal characteristics (neonatal gender, Apgar score, Cesarean delivery, birth weight < 10th percentile, birth weight < 3rd percentile) were matched with those of the late preterm cases. We compared categorical variables using Fisher’s exact test. For variables with a non-normal distribution, Welch’s t-test was applied. A p-value of <0.05 was considered to be statistically significant. Results: The rate of return of the questionnaires was 25.9% (121) among the cases and 25.8% (163) among the controls. The frequency of developmental delays was 6.6% among the cases, compared with 4.3% among the controls. Conclusions: Matching the perinatal characteristics of the subjects, the frequency of developmental delays was similar between the two groups.
文摘目的探讨晚期早产儿呼吸系统疾病患病的临床特点。方法选取2009年1月至2010年12月在我院产科出生的新生儿,其中晚期早产儿(胎龄34～36+6周)630例,足月儿4401例,早期早产儿(胎龄≤33+6周)328例。其中患呼吸系统疾病者包括晚期早产儿84例,足月儿135例,早期早产儿182例。比较3组新生儿呼吸系统疾病发病情况、临床特点及危重程度。结果 (1)晚期早产儿组呼吸系统疾病发生率、病死率及危重症比例均高于足月儿组,而低于早期早产儿组(P<0.01)。(2)晚期早产儿组呼吸困难起病时间早于足月儿组,晚于早期早产儿组(P<0.01);呼吸增快百分比较其他两组高,而三凹征百分比较低(P<0.05);晚期早产儿组需氧疗及机械通气的比例均明显高于足月儿组,而低于早期早产儿组(P<0.05)。(3)多元线性回归分析发现血氧分压降低、红细胞压积减低、血pH值减低、呼吸减慢、动脉血氧饱和度减低、动脉收缩压减低、5 min Apgar评分减低、胎龄较小、血尿素氮增高、心率增快、呼吸增快是新生儿呼吸系统疾病危重症的影响因素。结论晚期早产儿比足月儿更容易出现呼吸系统疾病,危重程度较重,需加强呼吸支持。晚期早产儿呼吸困难多表现为呼吸增快,起病时间早于足月儿而晚于早期早产儿。对于晚期早产儿,如发现呼吸困难、心率、血压异常及多系统受累表现,常提示其病情危重,应积极治疗。
