Background: Lewy body disease (LBD) is a neurodegenerative affection responsible for impaired quality of life. The objective was to share the data experience of 14 years concerning the functional, neuropsychological a...Background: Lewy body disease (LBD) is a neurodegenerative affection responsible for impaired quality of life. The objective was to share the data experience of 14 years concerning the functional, neuropsychological and behaviors effects on geriatrics patients. Methodology: Descriptive retrospective study over 14 years (2005 to 2019) in the geriatrics department of Pitié Salpétrière Hospital, using the instrumentals activity of daily living (IADL) sheets and the neuropsychological inventory (NPI) assessed at the moment diagnosis according to the diagnostic criteria of 2017 and 1996. Results: A total of 70 patients including 55 exploitable files had been listed with a mean age 82.6 years [70 - 91], a sex ratio 1.2 in men favor, a mean socio-cultural level 5.2 [1 - 7], a mean Cumulating Illness Scale (CIRS52) = 10 [1 - 22]. The mean IADL and NPI were respectively 9.3 [3 - 11] and 25.1 [0 - 79]. We found an early global impairment of IADL activities frequent in transport (65%), medication management (49%), and displacement (42%) for basic activities without significant statistical difference between the age and sex groups but statistically significant early involvement with polypathology after adjustment for displacement (45%) and transport (65%). The IADL impairment is significant as soon as the MMS-BREF decreases. Hoen Yahr (HY) scale increase could influences shopping (22%), displacement (27%) after adjustment. NPI disorders frequently found were apathy-depression (31.8% - 25%), anxiety (28%), irritability (25.6%) and sleep disturbance (22.9%) after 80 years old independently of gender and poly-pathology. Also, the best mental status was associated of less disturbance of NPI items. Conclusion: Polypathology, motor disorders and cognitive decline seem to influence IADL while with advanced age, cognitive decline appears to be worsened early in LBD.展开更多
Atomic-undercoordination-induced local bond contraction,bond strength gain,and the associated temperature (T)-dependent atomic-cohesive-energy and binding-energy-density are shown to originate intrinsically the exotic...Atomic-undercoordination-induced local bond contraction,bond strength gain,and the associated temperature (T)-dependent atomic-cohesive-energy and binding-energy-density are shown to originate intrinsically the exotic paradox of superplasticity,superelasticity,and superrigidity demonstrated by solid sizing from monatomic chain to mesoscopic grain.The paradox follows these relationships:(ε(K,T)y(K,T)σ(K,T))∝(exp(B/△T_(mk)),(η_1△T_(mk))d～(-3),[1+AK～(-2/2)exp(△T_(mk)/T)]△T_(mk)d～(-3)),(Plastic strain)(Elastic modulus)(Yield stress,IHPR)where A,B,η1,d and△T_(mk)=Tm(K) Tare size (K)-dependent physical parameters.Tm (K) is the melting point.Mechanical work hardening during compressing and self-heating during stretching modulate the measured outcome extrinsically.Superplasticity dominates in the solid-quasimolten-liquid transition state.The competition between the accumulation and annihilation of dislocations activates the inverse Hall-Petch relationship.Therefore,it is essential for one to discriminate the intrinsic competition between the local bond energy density gain and the atomic cohesive energy loss from the extrinsic factors of pressure and temperature in dealing with atomistic mechano-thermo dynamics.展开更多
With the weighted modulus of smoothness as a metric,we prove the direct and the inverse theorems of approximation by Bernstein-Durrmeyer operators in LBa M spaces. Especially an approximation equivalent theorem of the...With the weighted modulus of smoothness as a metric,we prove the direct and the inverse theorems of approximation by Bernstein-Durrmeyer operators in LBa M spaces. Especially an approximation equivalent theorem of the operators is also obtained.展开更多
We sought to identify the differences between adolescents left behind in their home villages/towns （LBA） and non-left behind adolescents （NLB） on subjective well-being and family functioning due to parental migrat...We sought to identify the differences between adolescents left behind in their home villages/towns （LBA） and non-left behind adolescents （NLB） on subjective well-being and family functioning due to parental migration in south China. We used a stratified cluster sampling method to recruit middle school students in a city experiencing population-emigration in Jiangxi Province in 2010. Participants included adolescents from families with： （1） one migrant parent, （2） both parents who migrated, or （3） non-left behind adolescents （i.e., no migrant parent）. To determine predictors of subjective well-being, we used structural equation models. Adolescents left behind by both parents （LBB） were less likely to express life satisfaction （P = 0.038） in terms of their environments （P = 0.011） compared with NLB. A parent or parents who migrated predicts lower subjective well-being of adolescents （P = 0.051） and also lower academic performance. Being apart from their parents may affect family functioning negatively from an adolescent＇s viewpoint. Given the hundreds of millions of persons in China, many who are parents, migrating for work, there may be mental health challenges in some of the adolescents left behind.展开更多
文摘Background: Lewy body disease (LBD) is a neurodegenerative affection responsible for impaired quality of life. The objective was to share the data experience of 14 years concerning the functional, neuropsychological and behaviors effects on geriatrics patients. Methodology: Descriptive retrospective study over 14 years (2005 to 2019) in the geriatrics department of Pitié Salpétrière Hospital, using the instrumentals activity of daily living (IADL) sheets and the neuropsychological inventory (NPI) assessed at the moment diagnosis according to the diagnostic criteria of 2017 and 1996. Results: A total of 70 patients including 55 exploitable files had been listed with a mean age 82.6 years [70 - 91], a sex ratio 1.2 in men favor, a mean socio-cultural level 5.2 [1 - 7], a mean Cumulating Illness Scale (CIRS52) = 10 [1 - 22]. The mean IADL and NPI were respectively 9.3 [3 - 11] and 25.1 [0 - 79]. We found an early global impairment of IADL activities frequent in transport (65%), medication management (49%), and displacement (42%) for basic activities without significant statistical difference between the age and sex groups but statistically significant early involvement with polypathology after adjustment for displacement (45%) and transport (65%). The IADL impairment is significant as soon as the MMS-BREF decreases. Hoen Yahr (HY) scale increase could influences shopping (22%), displacement (27%) after adjustment. NPI disorders frequently found were apathy-depression (31.8% - 25%), anxiety (28%), irritability (25.6%) and sleep disturbance (22.9%) after 80 years old independently of gender and poly-pathology. Also, the best mental status was associated of less disturbance of NPI items. Conclusion: Polypathology, motor disorders and cognitive decline seem to influence IADL while with advanced age, cognitive decline appears to be worsened early in LBD.
基金supports from the National Natural Science Foundation of China(Grant Nos. 11002121,11102176 and 11172254)
文摘Atomic-undercoordination-induced local bond contraction,bond strength gain,and the associated temperature (T)-dependent atomic-cohesive-energy and binding-energy-density are shown to originate intrinsically the exotic paradox of superplasticity,superelasticity,and superrigidity demonstrated by solid sizing from monatomic chain to mesoscopic grain.The paradox follows these relationships:(ε(K,T)y(K,T)σ(K,T))∝(exp(B/△T_(mk)),(η_1△T_(mk))d～(-3),[1+AK～(-2/2)exp(△T_(mk)/T)]△T_(mk)d～(-3)),(Plastic strain)(Elastic modulus)(Yield stress,IHPR)where A,B,η1,d and△T_(mk)=Tm(K) Tare size (K)-dependent physical parameters.Tm (K) is the melting point.Mechanical work hardening during compressing and self-heating during stretching modulate the measured outcome extrinsically.Superplasticity dominates in the solid-quasimolten-liquid transition state.The competition between the accumulation and annihilation of dislocations activates the inverse Hall-Petch relationship.Therefore,it is essential for one to discriminate the intrinsic competition between the local bond energy density gain and the atomic cohesive energy loss from the extrinsic factors of pressure and temperature in dealing with atomistic mechano-thermo dynamics.
基金Supported by the 2007 Year School Grade Plan Item of Inner Mongolia University for Nationalities(MDX2007030)
文摘With the weighted modulus of smoothness as a metric,we prove the direct and the inverse theorems of approximation by Bernstein-Durrmeyer operators in LBa M spaces. Especially an approximation equivalent theorem of the operators is also obtained.
基金supported by Sub Four Programme of Public Health Welfare Research Special Funds[grants No.201202010]Natural Science Fund Commission of China[H2609/81673232]the Yale Center for Interdisciplinary Research on Acquired Immune Deficiency Syndrome supported by National Institutes of Health grant[P30MH062294]
文摘We sought to identify the differences between adolescents left behind in their home villages/towns （LBA） and non-left behind adolescents （NLB） on subjective well-being and family functioning due to parental migration in south China. We used a stratified cluster sampling method to recruit middle school students in a city experiencing population-emigration in Jiangxi Province in 2010. Participants included adolescents from families with： （1） one migrant parent, （2） both parents who migrated, or （3） non-left behind adolescents （i.e., no migrant parent）. To determine predictors of subjective well-being, we used structural equation models. Adolescents left behind by both parents （LBB） were less likely to express life satisfaction （P = 0.038） in terms of their environments （P = 0.011） compared with NLB. A parent or parents who migrated predicts lower subjective well-being of adolescents （P = 0.051） and also lower academic performance. Being apart from their parents may affect family functioning negatively from an adolescent＇s viewpoint. Given the hundreds of millions of persons in China, many who are parents, migrating for work, there may be mental health challenges in some of the adolescents left behind.
