BACKGROUND: The purpose of the study was to explore the association between posttraumatic stress disorder(PTSD) and work performance of emergency medical services personnel in Karachi, Pakistan.METHODS: Emergency medi...BACKGROUND: The purpose of the study was to explore the association between posttraumatic stress disorder(PTSD) and work performance of emergency medical services personnel in Karachi, Pakistan.METHODS: Emergency medical service personnel were screened for potential PTSD using Impact of Event Scale-Revised(IES-R). Work performance was assessed on the basis of fi ve variables: number of late arrivals to work, number of days absent, number of days sick, adherence to protocol, and patient satisfaction over a period of 3 months. In order to model outcomes like the number of late arrivals to work, days absent and days late, negative binomial regression was applied, whereas logistic regression was applied for adherence to protocol and linear for patient satisfaction scores.RESULTS: Mean scores of PTSD were 24.0±12.2. No association was found between PTSD and work performance measures: number of late arrivals to work(RRadj 0.99; 0.98–1.00), days absent(RRadj 0.98; 0.96–0.99), days sick(RRadj 0.99; 0.98–1.00), adherence to protocol(ORadj 1.01; 0.99–1.04) and patient satisfaction(β 0.001%–0.03%) after adjusting for years of formal schooling, living status, coping mechanism, social support, working hours, years of experience and anxiety or depression.CONCLUSION: No statistically significant association was found between PTSD and work performance amongst EMS personnel in Karachi, Pakistan.展开更多
Under the steadily intensifying human activities in coastal areas,it is crucial to distinguish the sources of organic matter(OM)in sediments for better understanding of the environmental change.In this study,25 surfac...Under the steadily intensifying human activities in coastal areas,it is crucial to distinguish the sources of organic matter(OM)in sediments for better understanding of the environmental change.In this study,25 surface sediments collected along the harbor and creeks areas off Karachi coast were used for total organic carbon(TOC),total nitrogen(TN),stable carbon(δ^(13)C)and nitrogen(δ^(15)N)isotopic compositions,phytoplankton biomarkers(brassicasterol,dinosterol and cholesterol)and glycerol dialkyl glycerol tetraethers(GDGTs)analyses,to trace the distribution of OM and identify its sources.TOC,TN,δ^(13)C,and δ^(15)N are in the range of 0.04% to 5.28%,0.01% to 0.57%,-17.55‰ to -26.31‰,and 2.83‰ to 6.04‰,respectively.C/N values range from 4.24 to 21.04.The δ^(13)C,δ^(15)N,C/N,BIT(Branched Isoprenoid Tetraether)index together with phytoplankton biomarkers show both marine and terrestrial OM input to the creeks and Harbor stations.In contrast,the stations from Western Coast indicate a marine source predominance.A clearly impact of human activities is seen from sediments near river mouths.展开更多
Inserting Groundwater quality variability and sources potentially contributing to aquifer recharge was evaluated in metropolitan Karachi. Selected sampling sites were characterized by large waste dumping sites, indust...Inserting Groundwater quality variability and sources potentially contributing to aquifer recharge was evaluated in metropolitan Karachi. Selected sampling sites were characterized by large waste dumping sites, industrial zones, and the presence of open streams receiving heavy loads of industrial and domestic wastes. Levels of pH, electrical conductivity (EC), fluoride (F-), chloride (Cl-), bromide (Br-), nitrate-N (NO-3-N), sulfate (SO2-4), sodium (Na+), potassium (K+), calcium (Ca2+), magnesium (Mg2+), and ammonium (NH+4) were determined and compared with the WHO permissible limits. Concentrations of the measured ions were in the order of Cl- > Na+ > SO2-4 > Mg2+ > Ca2+ > NO-3-N > K+ > F- > Br-. EC values were above the WHO guidelines, representing the presence of high ionic concentration in the groundwater. The health risk index (HRI) for indicated that inhabitants of Karachi are at risk of high exposure. Ingestion of high concentrations of NO-3-N in water can cause methemoglobinemia and birth defects. Results of multivariate statistical analysis, principal component analysis (PCA), cluster analysis (CA), and geographic information system (GIS) map analysis revealed that human activities are leading to adverse effects on the existing groundwater quality in Karachi.展开更多
The temporal variations of mesozooplankton abundance and biomass (1-Volumetric method by settling volume and displacement volume and 2- Gravimetric method through wet weight, dry weight and ash-free dry weight) with...The temporal variations of mesozooplankton abundance and biomass (1-Volumetric method by settling volume and displacement volume and 2- Gravimetric method through wet weight, dry weight and ash-free dry weight) with relation to environmental parameters were studied in the mangrove creek area of Karachi coast, Pakistan. The data of mesozooplankton samples along with environmental parameters (temperature, salinity, pH, etc.) were collected during January 1998 to December 1998 from two creek stations. The abun-dance of mesozooplankton also exhibited seasonal trends at both stations. At Sta. S2, the highest and low-est abundance values were observed during post-monsoon and southwest monsoon respectively whereas, at Sta. S1, a clear trend of high abundance in pre-monsoon to low abundance in southwest monsoon was observed. Mesozooplankton abundance was also positively correlated with settling volume, displacement volume, wet weight and dry weight. The highest biomass value was observed in the northeast monsoon and pre-monsoon periods. The results of the canonical analysis of the output from the discriminate function was tested. Out of fifteen variables, only one was significantly different in single character ratios dry weight/ash free-dry weight (F3,23=4.78,P<0.005). The mesozooplankton community was collectively composed of 28 taxa. Among these groups, copepoda (66.3%), gastropod larvae (9.94%), evadne (4.60%), zoea (3.60%), cypris nauplii (2.56%), lemellibranch larvae (1.87%), chaetognaths (1.81%), ostracods (1.73%), lucifer (1.15%) and barnacles nauplii (1.35%) contributed the most to the similarities within Sta. S1, while copepoda (74.68%), cypris nauplii (5.29%), gastropods (4.87%), barnacles nauplii (4.81%), evadne (1.72%), zoea (1.53%) and ca-ridean larvae (1.18%) at Sta. S2. The remaining mesozooplanktonic group were accounted for less than 5% and 6% at Sta. S1 and Sta. S2 respectively, of the total organisms. Similarity perce展开更多
The urban centers of developing countries like Karachi city in Pakistan are facing the menace of air pollution and atmospheric wet deposition can be used as a tool for monitoring the quality of air. In this study, rai...The urban centers of developing countries like Karachi city in Pakistan are facing the menace of air pollution and atmospheric wet deposition can be used as a tool for monitoring the quality of air. In this study, rainwater samples from eighteen different towns of Karachi were collected during monsoon season (July to September, 2013) in triplicate and analyzed. Their pH (range 6.2 - 7.9), electrical conductivity (range 0.02 - 0.21 m·S/cm), total dissolved solids (range 32 - 159 mg/l), dissolved oxygen (range 6.3 - 8.2 mg/l) and hardness (23 - 89 mg/l) were immediately monitored within next twenty four hours of sample collections. The samples were then acidified and analyzed for the presence of major cations ammonium, sodium, potassium, magnesium and calcium by flame atomic absorption spectroscopy and flame emission spectroscopy. The anions fluoride, chloride, nitrate, carbonate and sulphate were analyzed by ion chromatography. The results of the analysis were compared with the values provided by WHO guidelines in order to access the quality of water. Most of the rainwater samples were completely free from considerable pollution and meet the WHO standard values. However, in Lyari, Gulshan, Shah Faisal, Landhi, Malir and Gadap town the concentration of Mg2+ and in North Nazimabad, Korangi, Gulshan, Saddar, Lyari, SITE and Keamari town the concentration of?N3- is above the WHO standards, indicating their presence from air pollution.展开更多
The World Health Organization (WHO), Environmental Protection Agency (EPA), and International Atomic Energy Agency (IAEA) have recommended the use of hair for worldwide environmental monitoring. Mercury exposure to th...The World Health Organization (WHO), Environmental Protection Agency (EPA), and International Atomic Energy Agency (IAEA) have recommended the use of hair for worldwide environmental monitoring. Mercury exposure to the inhabitants of Karachi was assessed by using hair as bioindicator. Hair samples of 200 residents of Karachi were collected and analyzed through cold vapor atomic absorption spectroscopy (CVAA) technique for mercury concentration. The effects of age, gender, working status, location, food and smoking habit were investigated. Control region showed a positive correlation between HHg and age of donor while no such correlation was observed for polluted regions. Mercury exposure through cosmetic usage in female was only pronounced in control region. These results indicate that environmental pollution dominates other potential factors. Age and smoking habit were not found to be the influencing factors while an elevated mean level of mercury was noticed for regular fish consumers than rarely fish consumers. 95.33% of the samples contained HHg greater than the permissible level of 2 μg?g?1 set by WHO. An apparently healthy male donor had HHg concentration (28.24 μg?g?1) closer to the high risk concentration of 30 μg?g?1 based on WHO criteria. Whereas, two female donors of the age group of 41-50 years had HHg concentrations (10.82 and 11.84 μg?g?1) higher than the NOAEL (no observed adverse affects level) value (10 μg?g?1) for females which is associated with fetus neurotoxicity. However, no symptoms of mercury toxicity were visible. The results indicate the alarming condition of pollution in the city which should be taken into further consideration.展开更多
<span style="font-family:Verdana;">Healthy youth is an asset and strength for economic and social growth of any society. Developmental changes during puberty of youngsters need proper guidance to avoid...<span style="font-family:Verdana;">Healthy youth is an asset and strength for economic and social growth of any society. Developmental changes during puberty of youngsters need proper guidance to avoid future physical, physiological and psychological ailments. Bilateral Retractile Testis (BRT) is a health problem if remains unnoticed till adolescence can lead to tribulations. BRT may affect testicular parenchyma and spermatogenesis. Cremasteric muscles (muscles attached with testes) pull the testes up into groin so it randomly moves up and down and do not reside in its natural pouch always. It has been a controversial issue in male infertility as retraction may </span><span style="font-family:Verdana;">a</span><span style="font-family:;" "=""><span style="font-family:Verdana;"><span style="font-family:Verdana;">ffect infertility. </span><b></b></span><b><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"></span></b><span style="font-family:Verdana;"> To estimate the prevalence of male infertility among patients with Bilateral Retractile Testis. </span><b></b></span><b><b><span style="font-family:Verdana;">Methodology:</span></b><span style="font-family:Verdana;"></span></b><span style="font-family:Verdana;"> A total of 200 male patients were enrolled after the power calculation, with different reproductive health problems between the age of 18</span> <span style="font-family:Verdana;">-</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> 40 years during the year 2016 at Reproductive health clinic Jinnah Post Graduate Medical Center (JPMC), Karachi. 25 male patients were reported with infertility and BRT. The data was collected using self-developed questionnaire including outdoor patients’ physical check-up, manual testicular examination as size and shape were done. Patient height, weight, blood pressure, their lifestyle, and dressing regarding wearing tight jeans habits were asked. Semen analysis was carried out showing abnormality in sperm count,展开更多
To determine the dynamic physical strain exerted on an individual during work, an evaluation of all physical performances is necessary. For surgeons, sustaining healthy ergonomics is essential, particularly for cases ...To determine the dynamic physical strain exerted on an individual during work, an evaluation of all physical performances is necessary. For surgeons, sustaining healthy ergonomics is essential, particularly for cases requiring long standing hours. Indeed, the absence of proper ergonomics may lead to multiple musculoskeletal issues. Failure to check these problems may lead to future degenerative changes and eventually career-ending damages. Pain among surgeons is expected since they spend many hours caring for patients that they ignore their health, standing for prolonged hours. Lack of attention to work ergonomics often leads to work-related muscle pain and increased risk of problems.展开更多
Among several lithostratigraphic subdivisions of the Ga Formation of Miocene age,the Jhill limestone is entirely different with respect to its colour, texture and structures. This limestone unit has been evaluated to ...Among several lithostratigraphic subdivisions of the Ga Formation of Miocene age,the Jhill limestone is entirely different with respect to its colour, texture and structures. This limestone unit has been evaluated to elaborate its geochemical and sedimentological characteristics. The distribution of various elements in the acid-soluble fraction has been studied in order to determine their mineralogy, sedimentary environment, facies and diagenesis. Mineralogy,recrystallization and other diagenetic changes are the main factors affecting the distribution of trace elements and their mutual relationships in the limestones. Samples of the Jhill limestone show depletion in large-sized ions (Sr, Pb & K) and also in the ions that are not compatible with calcite space group. Elements (Fe, Mn, Zn, Cu & Co) having distribution eoefficient (D) above unity for natural calcites, are more enriched. Microscopic and X-ray studies revealed nearly complete conversion of aragonite into stable low-Mg calcite.An attempt has also been made to verify the reefal conditions for these limestones on the basis of geochemical studies. The plots of Sr and other facies-indicator elements show that the majority of the beds belong to forereef flank facies with some algal banks. Low Mg/Ca and Sr/Ca ratios suggest that a phreatic diagenetic environment prevailed after the deposilion. High concentrations of Cr, Ni, and Co in the Jhill limestone show a positive correlation with a higher amount of insoluble residue, which reflects a relatively high rate of influx of terrigenous material.展开更多
Objective: To determine heavy metal concentrations in holothurians (Holothuria arenicola, Holothuria pardalis, Holothuria verrucosa, Holothuria atra, Ohshimella ehrenbergii, Holothuria cinerascens, Stolus buccalis and...Objective: To determine heavy metal concentrations in holothurians (Holothuria arenicola, Holothuria pardalis, Holothuria verrucosa, Holothuria atra, Ohshimella ehrenbergii, Holothuria cinerascens, Stolus buccalis and Holothuria leucospilota), sediments and sea water samples from both Buleji and Sunehri coasts bordering Northern Arabian Sea during January to December 2014 and to assess the level of bioaccumulation using bioaccumulation factors. Methods: Fe, Mn, Zn, Cu, Cd and Pb levels were determined by Perkin Elmer AAnalyst 700 Atomic Absorption Spectrophotometer. Biota concentration factor (BCF) and biota sediment accumulation factor (BSAF) were also calculated. Results: The mean concentrations of heavy metals in body wall of sea cucumber ranged from 0.11 to 2.67, 0.43 to 8.93, 14 to 73, 0.76 to 7.12, 0.52 to 3.02 and 11 to 46 μg/g dry wright for Cd, Cu, Fe, Mn, Pb and Zn, respectively. The greatest biota-sediment bioaccumulation factor (BSAF) value for Zn (3.29) was observed in H. leucospilota at Buleji during pre-monsoon, indicating the species as microconcentrator. The BSAF values for Cd in sea cucumber ranged from 0.042 to 1.492. Conclusions: The results suggested that the studied sea cucumber species ranged from being microconcentrators to deconcentrators. The BSAF values of Cu, Fe, Mn and Pb were low, indicating the species as deconcentrators. Zn in all species from Sunehri coast is 'very bioaccumulative' (BCF > 5000) during all sampling periods. Cu, Fe, Mn and Pb can be considered 'bioaccumulative' (BCF < 5000).展开更多
Objective:To document the traditional uses of wild plants as medicine by the villagers along the coastal highway from Karachi to Uthal.Methods:Information presented in this research was gathered from the local people ...Objective:To document the traditional uses of wild plants as medicine by the villagers along the coastal highway from Karachi to Uthal.Methods:Information presented in this research was gathered from the local people using an integrated approach of floral collections,discussions with the elderly people and traditional medicinal practitioners using semi-structured questionnaire.Results:27 families in the targeted area.Majority of the plants(54%)from this coastal plant diversity were xerophytes followed by halophytes/xero-halophytes(40%)and glycophytes(6%).The most important uses included gastrointestinal diseases,pain killer,arthritis,skin and sexual disorders,asthma and expectorant.The above-ground parts of plants i.e.leaf,stem and fruit/seed as decoction are used most commonly to cure 23 ailments but root was also used in some cases.Conclusions:Ethno-medicinal surveys indicated the medicinal importance of 54 plant species from phyto-medicinal claim and it is hoped that it will lead to detailed chemical and pharmacological evaluations.This may also lead to a discovery of novel bioactive compounds for food and pharmaceutical industries.This study helps in documenting therapeutic uses of herbal remedies with new pevhayltou-amtioendsic.iTnhali sc lmaiamy aanldso i tl iesa hdo tpoe da tdhiastc iot vweirlyl loeaf dn otov edle tbaiioleadc tcihveem ciocmalp aonudn pdhs afromr afcoooldog aicnadl pharmaceutical industries.展开更多
A geomagnetic observatory was established at Karachi (geog coord: 24.95°N, 167.14° E), Pakistan in 1983 which comprised of AMOS-Ⅲ (Automatic Magnetic Observatory System). In 2006 SUPARCO (Space and Up...A geomagnetic observatory was established at Karachi (geog coord: 24.95°N, 167.14° E), Pakistan in 1983 which comprised of AMOS-Ⅲ (Automatic Magnetic Observatory System). In 2006 SUPARCO (Space and Upper Atmosphere Research Commission) planned to upgrade the old observatory of Karachi in order to qualify it as an IMO (Intermagnet Magnetic Observatory). Dr. Jean Rasson agreed to give support and assist us in the upgradation. BGS (British Geological Survey) provided a complete observatory instrument setup. Due to perturbations traceable to the increased urbanization, the observatory has been shifted to a site "Sonmiani", 80 km north-west of Karachi, where long term protection from cultural noise is offered. This site in a sparsely built research complex was selected after a magnetic survey. A new observatory has also been established at Islamabad (geog cord: 33.75° N, 72.87° E) which is mountainous region. SUPARCO purchased new equipment for the establishment of new observatories. Plan of upgradation of observatory at Quetta is also under consideration in order to improve the monitoring of geomagnetic field on the western part of Pakistan. Repeat station work has been done for the northern part of Pakistan with the collaboration of IRM, Belgium. The obtained results also compared with the global geomagnetic model (IGRF).展开更多
Barn Owl (Tyto alba) pellets were collected from nine locations and two districts of Sindh,Pakistan and 937 prey items were recovered from 619 pellets.Rats/mice (59.6%) were the most dominant food items consumed by th...Barn Owl (Tyto alba) pellets were collected from nine locations and two districts of Sindh,Pakistan and 937 prey items were recovered from 619 pellets.Rats/mice (59.6%) were the most dominant food items consumed by the Barn Owl.Shrews (22.3%),bats (1.3%),birds (12.0%),insects (1.3%),frogs (2.2%) and plant materials (1.3%) were found in their diet as well.Study of the pelvic girdle bones of rats/mice,used only for sexing,proved to be a useful device in population dynamics.In the pelvic bone,pelvic symphysis is found only in female rats/mice developed as a result of sex hormones that occur during gestation.Among the diet of rats/mice,males were found to be significantly dominant.Tooth wear patterns on the occlusal surfaces of molariform teeth of the rats/mice were found to provide an effective criterion for establishing age classes of rats/mice.In the present study,adult rats/mice were found to be dominant over sub-adults and old adults.ANOVA showed significant differences in the number of rats/mice and shrews (prey items) and the other prey items/plant materials in the diet of Barn Owls in the district Thatta and district Karachi.Chi-square test disclosed non-significant differences in age and sex categories.展开更多
Objective: To determine the levels of six heavy metals in the liver and edible tissues of different sizes of Drepane longimana collected at Karachi fish harbor of Pakistan during fisheries seasons in 2016. Methods: Th...Objective: To determine the levels of six heavy metals in the liver and edible tissues of different sizes of Drepane longimana collected at Karachi fish harbor of Pakistan during fisheries seasons in 2016. Methods: The concentrations of iron (Fe), zinc (Zn), copper (Cu), manganese (Mn), lead (Pb) and cadmium (Cd) were carried out using Atomic Absorption Spectrophotometer (AAS, Aanalyst 700). Results: In muscle and liver tissues, Fe is detected in highest concentrations, followed by Zn, Cu, Mn, Cd and Pb. Concentrations of Cd and Pb of some individuals were not detected in the edible tissues. Large differences in these metal concentrations were observed between different tissues within each size of fish except Mn in 24–28 cm sizes. The liver of Drepane longimana accumulates significant higher levels of metals than those in the edible tissues. Conclusions: Based on the results of this study, the bioaccumulation of metals in the muscles of concertina fish did not exceed the permissible limits set for heavy metals by European Commission Regulation, Food and Agriculture Organization and Turkish Food Codex. It could be concluded that there is no risk in consumption of Concertina fish from Karachi fish harbor of Pakistan in 2016.展开更多
Objective:To assess the community structure,seasonal dynamics of dinoflagellates population with environmental conditions in the nutrient-rich and polluted coastal waters off,Karachi.Methods:Sampling sites were locate...Objective:To assess the community structure,seasonal dynamics of dinoflagellates population with environmental conditions in the nutrient-rich and polluted coastal waters off,Karachi.Methods:Sampling sites were located from Karachi harbour(Station A)and Mouth of Manora Channel(Station B).Total 180 replicate samples were collected at 1-m depth through Niskin bottle sampler(1.7 L)and fixed with 2%lugol’s preservative then examined under light inverted microscopy,scanning electron and epiflourescence microscope.Results:The environmental conditions,such as temperature[(20-27)°C],salinity[(35-40)psu],chlorophyll a[(1-103)μg/L],pH(6.03-8.13)and dissolve oxygen[(0.7-5.5)mg/L]were recorded from both stations.A total of 96 species were identified into potential harmful toxic/non-toxic bloom forming species and cysts producer.Total dinoflagellate cells between two coastal sites were much concentrated at the adjacent area of mouth of Manora Channel compare to harbor site.The dinoflagellate cell concentration ranging from 20 to~55000 cells/L and the maximum values observed in two season,(~55000 cells/L)in autumn and(~3000 cells/L)in winter season.Gyrodinium sp.was the predominant taxa with the maximum abundance(48166 cells/L)observed in autumn season following by Scrippsiella trochoidea(1200 cells/L),Alexandrium ostenfeldii(3000 cells/L)in winter season,and Ceratium furca(640 cells/L),Protoperidinium steinii(780 cells/L),Ceratium fusus(906 cells/L),Pyrophacus steinii(840 cells/L),Gonyaulax spinifera(666 cells/L),Alexandrium tamarense(520 cells/L)and Dinophysis caudata(393 cells/L)in summer and spring season.Statistically,abundance of dinoflagellates correlated significant to chlorophyll a with chlorophyll a and temperature but inverse relation to salinity and pH observed from both sites.Conclusions:The present study reports on the prevalence and significance of harmful algae bloom forming taxa in the area which would be available for the coastal zone managers and fishery industry to inform them of possible threat and dam展开更多
Objective:To describe the diet and feeding ecology ofHemiramphus far (H. far) through investigating the stomach contents. <br> Methods: Sampling of total 430 individuals ofH. far was carried out from commercial ...Objective:To describe the diet and feeding ecology ofHemiramphus far (H. far) through investigating the stomach contents. <br> Methods: Sampling of total 430 individuals ofH. far was carried out from commercial catches landed at West Wharf fish harbor of Karachi coast, Pakistan during January–December 2010. The total length and weight of each individual were recorded. Samples were parted into Group 1 (15–20 cm,n = 240) and Group 2 (21–26 cm,n = 190), to estimate changes in diet with fish size. To remove alimentary canal, fishes were dissected and kept into 10% formalin. Then gut contents were examined under a light microscope for each intestine. Stomach fullness as well as dietary composition was ascertained from gut contents. Examination and analyses were conducted using frequency of occurrence and numerical method. <br> Results:The examination confirmed 47.67% stomach as empty. Furthermore, our study revealed that the diet ofH. far consists of fishes, isopods, ostracods,Daphnia, shells, algae, unidentified plants and animal materials. This study proved thatH. far is an omnivorous fish feeding on fishes, isopods, shells, algae and plant and animal originated different food items. According to the Schoener overlap index, there was no significant difference in feeding of the two length groups ofH. far (C = 0.833). In addition, the Shannon-Wiener index presented that in Group 1, the prey diversity of the halfbeak was lower (H = 0.90) than that of Group 2 (H = 1.02). <br> Conclusions: The findings of the present study would be very effective for sustainable management of black-barred halfbeak fishery in the Karachi coast of Pakistan and the surrounding ecosystems.展开更多
Objective:To assess the arsenic(As)concentration in different parts of mangroves Avicenniamarina and sediments in Karachi coastal area i.e.Korangi Creek,Manora,Kakapir and Sandspit.Methods:Sites are identified for sam...Objective:To assess the arsenic(As)concentration in different parts of mangroves Avicenniamarina and sediments in Karachi coastal area i.e.Korangi Creek,Manora,Kakapir and Sandspit.Methods:Sites are identified for sampling owing to their vicinity to industrial activities.Sandspit is targeted for its being devoid of industries.The hydride generation atomic absorption spectrometry(HG-AAS)were used to analyse the concentration of arsenic in mangrove and sediment.Results:The high concentration of As was found in roots and middle aerial part as compared to the upper part of mangroves.The concentrations of As was found higher in sediments as compared to the mangroves.There is a seasonal variation of As enrichment in mangrove and sediments as dry seasons showed higher concentration while in rainy season dilution factors may be attributed to the low level of As.The concentration variation of As in sampling sites of mangroves and sediments following the trend i.e.Korangi Creek>Manora>Kakapir>Sandspit.The statistical analysis(Two way ANOVA)of data exhibited no significant difference(P>0.05)for trace metals concentrations in mangrove as well as in sediments.Conclusions:It is obvious to conclude that As should be continuously monitored in different environmental segments.The data must correlate with geographical distribution of As,quantification in different species,their solubility and bioavailability to understand the possible factors responsible for environmental pollution.The present study will be helpful to improve water management resources.展开更多
Objective:To assess the hepatoprotective effect of ethanol extracts of Sargassum variegatum(S.variegatum),Sargassum tenerrimum(S.tenerrimum)and Sargassum binderi occurring at Karachi coast against carbon tetrachloride...Objective:To assess the hepatoprotective effect of ethanol extracts of Sargassum variegatum(S.variegatum),Sargassum tenerrimum(S.tenerrimum)and Sargassum binderi occurring at Karachi coast against carbon tetrachloride(CCl_(4))and acetaminophen intoxication in rats.Methods:Sargassum species were collected at low tide from Buleji beach at Karachi coast.Effect of ethanol extracts of Sargassum spp.,on lipid parameter,serum glucose and kidney function was examined.Liver damage in rats was induced by CCl_(4) or acetaminophen.Rats were administered with ethanol extracts of S.tenerrimum,S.variegatum and Sargassum binderi at 200 mg/kg body weight daily for 14 days separately.Hepatotoxicity was determined in terms of cardiac and liver enzymes and other biochemical parameters.Results:S.variegatum showed highest activity by reducing the elevated level of hepatic enzymes,bilirubin,serum glucose,triglyceride with restoration of cholesterol.Urea and creatinine concentrations were also significantly(P<0.05)reduced as compared to acetaminophen intoxicated rats.S.tenerrimum and S.variegatum showed moderate activity against CCl_(4) hepatic toxicity.Conclusions:The protective role of S.variegatum against acetaminophen liver damage and its positive impact on disturbed lipid,glucose metabolism,kidney dysfunction and S.tenerrimum against CCl_(4) liver toxicity suggest that Sargassum species offer a non-chemical means for the treatment of toxicity mediated liver damage.展开更多
基金partially supported through the Johns Hopkins-Pakistan International Collaborative Trauma and Injury Research Training program(grant number 2D43-TW007-292)from the Fogarty International Center of the United States,National Institutes of Healthpartially supported from department of Community Health Sciences,Aga Khan University,Karachi,Pakistan
文摘BACKGROUND: The purpose of the study was to explore the association between posttraumatic stress disorder(PTSD) and work performance of emergency medical services personnel in Karachi, Pakistan.METHODS: Emergency medical service personnel were screened for potential PTSD using Impact of Event Scale-Revised(IES-R). Work performance was assessed on the basis of fi ve variables: number of late arrivals to work, number of days absent, number of days sick, adherence to protocol, and patient satisfaction over a period of 3 months. In order to model outcomes like the number of late arrivals to work, days absent and days late, negative binomial regression was applied, whereas logistic regression was applied for adherence to protocol and linear for patient satisfaction scores.RESULTS: Mean scores of PTSD were 24.0±12.2. No association was found between PTSD and work performance measures: number of late arrivals to work(RRadj 0.99; 0.98–1.00), days absent(RRadj 0.98; 0.96–0.99), days sick(RRadj 0.99; 0.98–1.00), adherence to protocol(ORadj 1.01; 0.99–1.04) and patient satisfaction(β 0.001%–0.03%) after adjusting for years of formal schooling, living status, coping mechanism, social support, working hours, years of experience and anxiety or depression.CONCLUSION: No statistically significant association was found between PTSD and work performance amongst EMS personnel in Karachi, Pakistan.
基金funded in part by the Ocean Negative Carbon Emissions(ONCE)Program,the Oceanic Interdisciplinary Program of Shanghai Jiao Tong University(No.SL2023MS019)the Scientific Research Fund of the Second Institute of Oceanography(No.JB2404)+3 种基金the National Natural Science Foundation of China(Nos.U23A2034,42076242,41941013,42176039,41906045)the Global Change and Air-Sea Interaction II Program(Nos.GASI-04-HYST-06,GASI-04-HYST-01)the Zhejiang Provincial Natural Science Foundation of China(No.LDT23D06023D06)the China Government Marine Scholarship。
文摘Under the steadily intensifying human activities in coastal areas,it is crucial to distinguish the sources of organic matter(OM)in sediments for better understanding of the environmental change.In this study,25 surface sediments collected along the harbor and creeks areas off Karachi coast were used for total organic carbon(TOC),total nitrogen(TN),stable carbon(δ^(13)C)and nitrogen(δ^(15)N)isotopic compositions,phytoplankton biomarkers(brassicasterol,dinosterol and cholesterol)and glycerol dialkyl glycerol tetraethers(GDGTs)analyses,to trace the distribution of OM and identify its sources.TOC,TN,δ^(13)C,and δ^(15)N are in the range of 0.04% to 5.28%,0.01% to 0.57%,-17.55‰ to -26.31‰,and 2.83‰ to 6.04‰,respectively.C/N values range from 4.24 to 21.04.The δ^(13)C,δ^(15)N,C/N,BIT(Branched Isoprenoid Tetraether)index together with phytoplankton biomarkers show both marine and terrestrial OM input to the creeks and Harbor stations.In contrast,the stations from Western Coast indicate a marine source predominance.A clearly impact of human activities is seen from sediments near river mouths.
文摘Inserting Groundwater quality variability and sources potentially contributing to aquifer recharge was evaluated in metropolitan Karachi. Selected sampling sites were characterized by large waste dumping sites, industrial zones, and the presence of open streams receiving heavy loads of industrial and domestic wastes. Levels of pH, electrical conductivity (EC), fluoride (F-), chloride (Cl-), bromide (Br-), nitrate-N (NO-3-N), sulfate (SO2-4), sodium (Na+), potassium (K+), calcium (Ca2+), magnesium (Mg2+), and ammonium (NH+4) were determined and compared with the WHO permissible limits. Concentrations of the measured ions were in the order of Cl- > Na+ > SO2-4 > Mg2+ > Ca2+ > NO-3-N > K+ > F- > Br-. EC values were above the WHO guidelines, representing the presence of high ionic concentration in the groundwater. The health risk index (HRI) for indicated that inhabitants of Karachi are at risk of high exposure. Ingestion of high concentrations of NO-3-N in water can cause methemoglobinemia and birth defects. Results of multivariate statistical analysis, principal component analysis (PCA), cluster analysis (CA), and geographic information system (GIS) map analysis revealed that human activities are leading to adverse effects on the existing groundwater quality in Karachi.
基金The Office of Naval Research(ONR)Project NP-30 grant
文摘The temporal variations of mesozooplankton abundance and biomass (1-Volumetric method by settling volume and displacement volume and 2- Gravimetric method through wet weight, dry weight and ash-free dry weight) with relation to environmental parameters were studied in the mangrove creek area of Karachi coast, Pakistan. The data of mesozooplankton samples along with environmental parameters (temperature, salinity, pH, etc.) were collected during January 1998 to December 1998 from two creek stations. The abun-dance of mesozooplankton also exhibited seasonal trends at both stations. At Sta. S2, the highest and low-est abundance values were observed during post-monsoon and southwest monsoon respectively whereas, at Sta. S1, a clear trend of high abundance in pre-monsoon to low abundance in southwest monsoon was observed. Mesozooplankton abundance was also positively correlated with settling volume, displacement volume, wet weight and dry weight. The highest biomass value was observed in the northeast monsoon and pre-monsoon periods. The results of the canonical analysis of the output from the discriminate function was tested. Out of fifteen variables, only one was significantly different in single character ratios dry weight/ash free-dry weight (F3,23=4.78,P&lt;0.005). The mesozooplankton community was collectively composed of 28 taxa. Among these groups, copepoda (66.3%), gastropod larvae (9.94%), evadne (4.60%), zoea (3.60%), cypris nauplii (2.56%), lemellibranch larvae (1.87%), chaetognaths (1.81%), ostracods (1.73%), lucifer (1.15%) and barnacles nauplii (1.35%) contributed the most to the similarities within Sta. S1, while copepoda (74.68%), cypris nauplii (5.29%), gastropods (4.87%), barnacles nauplii (4.81%), evadne (1.72%), zoea (1.53%) and ca-ridean larvae (1.18%) at Sta. S2. The remaining mesozooplanktonic group were accounted for less than 5% and 6% at Sta. S1 and Sta. S2 respectively, of the total organisms. Similarity perce
文摘The urban centers of developing countries like Karachi city in Pakistan are facing the menace of air pollution and atmospheric wet deposition can be used as a tool for monitoring the quality of air. In this study, rainwater samples from eighteen different towns of Karachi were collected during monsoon season (July to September, 2013) in triplicate and analyzed. Their pH (range 6.2 - 7.9), electrical conductivity (range 0.02 - 0.21 m·S/cm), total dissolved solids (range 32 - 159 mg/l), dissolved oxygen (range 6.3 - 8.2 mg/l) and hardness (23 - 89 mg/l) were immediately monitored within next twenty four hours of sample collections. The samples were then acidified and analyzed for the presence of major cations ammonium, sodium, potassium, magnesium and calcium by flame atomic absorption spectroscopy and flame emission spectroscopy. The anions fluoride, chloride, nitrate, carbonate and sulphate were analyzed by ion chromatography. The results of the analysis were compared with the values provided by WHO guidelines in order to access the quality of water. Most of the rainwater samples were completely free from considerable pollution and meet the WHO standard values. However, in Lyari, Gulshan, Shah Faisal, Landhi, Malir and Gadap town the concentration of Mg2+ and in North Nazimabad, Korangi, Gulshan, Saddar, Lyari, SITE and Keamari town the concentration of?N3- is above the WHO standards, indicating their presence from air pollution.
文摘The World Health Organization (WHO), Environmental Protection Agency (EPA), and International Atomic Energy Agency (IAEA) have recommended the use of hair for worldwide environmental monitoring. Mercury exposure to the inhabitants of Karachi was assessed by using hair as bioindicator. Hair samples of 200 residents of Karachi were collected and analyzed through cold vapor atomic absorption spectroscopy (CVAA) technique for mercury concentration. The effects of age, gender, working status, location, food and smoking habit were investigated. Control region showed a positive correlation between HHg and age of donor while no such correlation was observed for polluted regions. Mercury exposure through cosmetic usage in female was only pronounced in control region. These results indicate that environmental pollution dominates other potential factors. Age and smoking habit were not found to be the influencing factors while an elevated mean level of mercury was noticed for regular fish consumers than rarely fish consumers. 95.33% of the samples contained HHg greater than the permissible level of 2 μg?g?1 set by WHO. An apparently healthy male donor had HHg concentration (28.24 μg?g?1) closer to the high risk concentration of 30 μg?g?1 based on WHO criteria. Whereas, two female donors of the age group of 41-50 years had HHg concentrations (10.82 and 11.84 μg?g?1) higher than the NOAEL (no observed adverse affects level) value (10 μg?g?1) for females which is associated with fetus neurotoxicity. However, no symptoms of mercury toxicity were visible. The results indicate the alarming condition of pollution in the city which should be taken into further consideration.
文摘<span style="font-family:Verdana;">Healthy youth is an asset and strength for economic and social growth of any society. Developmental changes during puberty of youngsters need proper guidance to avoid future physical, physiological and psychological ailments. Bilateral Retractile Testis (BRT) is a health problem if remains unnoticed till adolescence can lead to tribulations. BRT may affect testicular parenchyma and spermatogenesis. Cremasteric muscles (muscles attached with testes) pull the testes up into groin so it randomly moves up and down and do not reside in its natural pouch always. It has been a controversial issue in male infertility as retraction may </span><span style="font-family:Verdana;">a</span><span style="font-family:;" "=""><span style="font-family:Verdana;"><span style="font-family:Verdana;">ffect infertility. </span><b></b></span><b><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"></span></b><span style="font-family:Verdana;"> To estimate the prevalence of male infertility among patients with Bilateral Retractile Testis. </span><b></b></span><b><b><span style="font-family:Verdana;">Methodology:</span></b><span style="font-family:Verdana;"></span></b><span style="font-family:Verdana;"> A total of 200 male patients were enrolled after the power calculation, with different reproductive health problems between the age of 18</span> <span style="font-family:Verdana;">-</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> 40 years during the year 2016 at Reproductive health clinic Jinnah Post Graduate Medical Center (JPMC), Karachi. 25 male patients were reported with infertility and BRT. The data was collected using self-developed questionnaire including outdoor patients’ physical check-up, manual testicular examination as size and shape were done. Patient height, weight, blood pressure, their lifestyle, and dressing regarding wearing tight jeans habits were asked. Semen analysis was carried out showing abnormality in sperm count,
文摘To determine the dynamic physical strain exerted on an individual during work, an evaluation of all physical performances is necessary. For surgeons, sustaining healthy ergonomics is essential, particularly for cases requiring long standing hours. Indeed, the absence of proper ergonomics may lead to multiple musculoskeletal issues. Failure to check these problems may lead to future degenerative changes and eventually career-ending damages. Pain among surgeons is expected since they spend many hours caring for patients that they ignore their health, standing for prolonged hours. Lack of attention to work ergonomics often leads to work-related muscle pain and increased risk of problems.
文摘Among several lithostratigraphic subdivisions of the Ga Formation of Miocene age,the Jhill limestone is entirely different with respect to its colour, texture and structures. This limestone unit has been evaluated to elaborate its geochemical and sedimentological characteristics. The distribution of various elements in the acid-soluble fraction has been studied in order to determine their mineralogy, sedimentary environment, facies and diagenesis. Mineralogy,recrystallization and other diagenetic changes are the main factors affecting the distribution of trace elements and their mutual relationships in the limestones. Samples of the Jhill limestone show depletion in large-sized ions (Sr, Pb & K) and also in the ions that are not compatible with calcite space group. Elements (Fe, Mn, Zn, Cu & Co) having distribution eoefficient (D) above unity for natural calcites, are more enriched. Microscopic and X-ray studies revealed nearly complete conversion of aragonite into stable low-Mg calcite.An attempt has also been made to verify the reefal conditions for these limestones on the basis of geochemical studies. The plots of Sr and other facies-indicator elements show that the majority of the beds belong to forereef flank facies with some algal banks. Low Mg/Ca and Sr/Ca ratios suggest that a phreatic diagenetic environment prevailed after the deposilion. High concentrations of Cr, Ni, and Co in the Jhill limestone show a positive correlation with a higher amount of insoluble residue, which reflects a relatively high rate of influx of terrigenous material.
文摘Objective: To determine heavy metal concentrations in holothurians (Holothuria arenicola, Holothuria pardalis, Holothuria verrucosa, Holothuria atra, Ohshimella ehrenbergii, Holothuria cinerascens, Stolus buccalis and Holothuria leucospilota), sediments and sea water samples from both Buleji and Sunehri coasts bordering Northern Arabian Sea during January to December 2014 and to assess the level of bioaccumulation using bioaccumulation factors. Methods: Fe, Mn, Zn, Cu, Cd and Pb levels were determined by Perkin Elmer AAnalyst 700 Atomic Absorption Spectrophotometer. Biota concentration factor (BCF) and biota sediment accumulation factor (BSAF) were also calculated. Results: The mean concentrations of heavy metals in body wall of sea cucumber ranged from 0.11 to 2.67, 0.43 to 8.93, 14 to 73, 0.76 to 7.12, 0.52 to 3.02 and 11 to 46 μg/g dry wright for Cd, Cu, Fe, Mn, Pb and Zn, respectively. The greatest biota-sediment bioaccumulation factor (BSAF) value for Zn (3.29) was observed in H. leucospilota at Buleji during pre-monsoon, indicating the species as microconcentrator. The BSAF values for Cd in sea cucumber ranged from 0.042 to 1.492. Conclusions: The results suggested that the studied sea cucumber species ranged from being microconcentrators to deconcentrators. The BSAF values of Cu, Fe, Mn and Pb were low, indicating the species as deconcentrators. Zn in all species from Sunehri coast is 'very bioaccumulative' (BCF > 5000) during all sampling periods. Cu, Fe, Mn and Pb can be considered 'bioaccumulative' (BCF < 5000).
基金Supported by Pakistan Academy of Sciences(Grant no:5-9/PAS,2010).
文摘Objective:To document the traditional uses of wild plants as medicine by the villagers along the coastal highway from Karachi to Uthal.Methods:Information presented in this research was gathered from the local people using an integrated approach of floral collections,discussions with the elderly people and traditional medicinal practitioners using semi-structured questionnaire.Results:27 families in the targeted area.Majority of the plants(54%)from this coastal plant diversity were xerophytes followed by halophytes/xero-halophytes(40%)and glycophytes(6%).The most important uses included gastrointestinal diseases,pain killer,arthritis,skin and sexual disorders,asthma and expectorant.The above-ground parts of plants i.e.leaf,stem and fruit/seed as decoction are used most commonly to cure 23 ailments but root was also used in some cases.Conclusions:Ethno-medicinal surveys indicated the medicinal importance of 54 plant species from phyto-medicinal claim and it is hoped that it will lead to detailed chemical and pharmacological evaluations.This may also lead to a discovery of novel bioactive compounds for food and pharmaceutical industries.This study helps in documenting therapeutic uses of herbal remedies with new pevhayltou-amtioendsic.iTnhali sc lmaiamy aanldso i tl iesa hdo tpoe da tdhiastc iot vweirlyl loeaf dn otov edle tbaiioleadc tcihveem ciocmalp aonudn pdhs afromr afcoooldog aicnadl pharmaceutical industries.
文摘A geomagnetic observatory was established at Karachi (geog coord: 24.95°N, 167.14° E), Pakistan in 1983 which comprised of AMOS-Ⅲ (Automatic Magnetic Observatory System). In 2006 SUPARCO (Space and Upper Atmosphere Research Commission) planned to upgrade the old observatory of Karachi in order to qualify it as an IMO (Intermagnet Magnetic Observatory). Dr. Jean Rasson agreed to give support and assist us in the upgradation. BGS (British Geological Survey) provided a complete observatory instrument setup. Due to perturbations traceable to the increased urbanization, the observatory has been shifted to a site "Sonmiani", 80 km north-west of Karachi, where long term protection from cultural noise is offered. This site in a sparsely built research complex was selected after a magnetic survey. A new observatory has also been established at Islamabad (geog cord: 33.75° N, 72.87° E) which is mountainous region. SUPARCO purchased new equipment for the establishment of new observatories. Plan of upgradation of observatory at Quetta is also under consideration in order to improve the monitoring of geomagnetic field on the western part of Pakistan. Repeat station work has been done for the northern part of Pakistan with the collaboration of IRM, Belgium. The obtained results also compared with the global geomagnetic model (IGRF).
文摘Barn Owl (Tyto alba) pellets were collected from nine locations and two districts of Sindh,Pakistan and 937 prey items were recovered from 619 pellets.Rats/mice (59.6%) were the most dominant food items consumed by the Barn Owl.Shrews (22.3%),bats (1.3%),birds (12.0%),insects (1.3%),frogs (2.2%) and plant materials (1.3%) were found in their diet as well.Study of the pelvic girdle bones of rats/mice,used only for sexing,proved to be a useful device in population dynamics.In the pelvic bone,pelvic symphysis is found only in female rats/mice developed as a result of sex hormones that occur during gestation.Among the diet of rats/mice,males were found to be significantly dominant.Tooth wear patterns on the occlusal surfaces of molariform teeth of the rats/mice were found to provide an effective criterion for establishing age classes of rats/mice.In the present study,adult rats/mice were found to be dominant over sub-adults and old adults.ANOVA showed significant differences in the number of rats/mice and shrews (prey items) and the other prey items/plant materials in the diet of Barn Owls in the district Thatta and district Karachi.Chi-square test disclosed non-significant differences in age and sex categories.
文摘Objective: To determine the levels of six heavy metals in the liver and edible tissues of different sizes of Drepane longimana collected at Karachi fish harbor of Pakistan during fisheries seasons in 2016. Methods: The concentrations of iron (Fe), zinc (Zn), copper (Cu), manganese (Mn), lead (Pb) and cadmium (Cd) were carried out using Atomic Absorption Spectrophotometer (AAS, Aanalyst 700). Results: In muscle and liver tissues, Fe is detected in highest concentrations, followed by Zn, Cu, Mn, Cd and Pb. Concentrations of Cd and Pb of some individuals were not detected in the edible tissues. Large differences in these metal concentrations were observed between different tissues within each size of fish except Mn in 24–28 cm sizes. The liver of Drepane longimana accumulates significant higher levels of metals than those in the edible tissues. Conclusions: Based on the results of this study, the bioaccumulation of metals in the muscles of concertina fish did not exceed the permissible limits set for heavy metals by European Commission Regulation, Food and Agriculture Organization and Turkish Food Codex. It could be concluded that there is no risk in consumption of Concertina fish from Karachi fish harbor of Pakistan in 2016.
基金Supported by international fellowship(International Research support of inititive program,IRSIP7-BMS-08),from HEC,Islamabad to Dr.Sonia Munir to work in USA.
文摘Objective:To assess the community structure,seasonal dynamics of dinoflagellates population with environmental conditions in the nutrient-rich and polluted coastal waters off,Karachi.Methods:Sampling sites were located from Karachi harbour(Station A)and Mouth of Manora Channel(Station B).Total 180 replicate samples were collected at 1-m depth through Niskin bottle sampler(1.7 L)and fixed with 2%lugol’s preservative then examined under light inverted microscopy,scanning electron and epiflourescence microscope.Results:The environmental conditions,such as temperature[(20-27)°C],salinity[(35-40)psu],chlorophyll a[(1-103)μg/L],pH(6.03-8.13)and dissolve oxygen[(0.7-5.5)mg/L]were recorded from both stations.A total of 96 species were identified into potential harmful toxic/non-toxic bloom forming species and cysts producer.Total dinoflagellate cells between two coastal sites were much concentrated at the adjacent area of mouth of Manora Channel compare to harbor site.The dinoflagellate cell concentration ranging from 20 to~55000 cells/L and the maximum values observed in two season,(~55000 cells/L)in autumn and(~3000 cells/L)in winter season.Gyrodinium sp.was the predominant taxa with the maximum abundance(48166 cells/L)observed in autumn season following by Scrippsiella trochoidea(1200 cells/L),Alexandrium ostenfeldii(3000 cells/L)in winter season,and Ceratium furca(640 cells/L),Protoperidinium steinii(780 cells/L),Ceratium fusus(906 cells/L),Pyrophacus steinii(840 cells/L),Gonyaulax spinifera(666 cells/L),Alexandrium tamarense(520 cells/L)and Dinophysis caudata(393 cells/L)in summer and spring season.Statistically,abundance of dinoflagellates correlated significant to chlorophyll a with chlorophyll a and temperature but inverse relation to salinity and pH observed from both sites.Conclusions:The present study reports on the prevalence and significance of harmful algae bloom forming taxa in the area which would be available for the coastal zone managers and fishery industry to inform them of possible threat and dam
文摘Objective:To describe the diet and feeding ecology ofHemiramphus far (H. far) through investigating the stomach contents. <br> Methods: Sampling of total 430 individuals ofH. far was carried out from commercial catches landed at West Wharf fish harbor of Karachi coast, Pakistan during January–December 2010. The total length and weight of each individual were recorded. Samples were parted into Group 1 (15–20 cm,n = 240) and Group 2 (21–26 cm,n = 190), to estimate changes in diet with fish size. To remove alimentary canal, fishes were dissected and kept into 10% formalin. Then gut contents were examined under a light microscope for each intestine. Stomach fullness as well as dietary composition was ascertained from gut contents. Examination and analyses were conducted using frequency of occurrence and numerical method. <br> Results:The examination confirmed 47.67% stomach as empty. Furthermore, our study revealed that the diet ofH. far consists of fishes, isopods, ostracods,Daphnia, shells, algae, unidentified plants and animal materials. This study proved thatH. far is an omnivorous fish feeding on fishes, isopods, shells, algae and plant and animal originated different food items. According to the Schoener overlap index, there was no significant difference in feeding of the two length groups ofH. far (C = 0.833). In addition, the Shannon-Wiener index presented that in Group 1, the prey diversity of the halfbeak was lower (H = 0.90) than that of Group 2 (H = 1.02). <br> Conclusions: The findings of the present study would be very effective for sustainable management of black-barred halfbeak fishery in the Karachi coast of Pakistan and the surrounding ecosystems.
基金Supported by Dean Science Grant,University of Karachi Pakistan(No.DSFR-/2011-2012).
文摘Objective:To assess the arsenic(As)concentration in different parts of mangroves Avicenniamarina and sediments in Karachi coastal area i.e.Korangi Creek,Manora,Kakapir and Sandspit.Methods:Sites are identified for sampling owing to their vicinity to industrial activities.Sandspit is targeted for its being devoid of industries.The hydride generation atomic absorption spectrometry(HG-AAS)were used to analyse the concentration of arsenic in mangrove and sediment.Results:The high concentration of As was found in roots and middle aerial part as compared to the upper part of mangroves.The concentrations of As was found higher in sediments as compared to the mangroves.There is a seasonal variation of As enrichment in mangrove and sediments as dry seasons showed higher concentration while in rainy season dilution factors may be attributed to the low level of As.The concentration variation of As in sampling sites of mangroves and sediments following the trend i.e.Korangi Creek>Manora>Kakapir>Sandspit.The statistical analysis(Two way ANOVA)of data exhibited no significant difference(P>0.05)for trace metals concentrations in mangrove as well as in sediments.Conclusions:It is obvious to conclude that As should be continuously monitored in different environmental segments.The data must correlate with geographical distribution of As,quantification in different species,their solubility and bioavailability to understand the possible factors responsible for environmental pollution.The present study will be helpful to improve water management resources.
文摘Objective:To assess the hepatoprotective effect of ethanol extracts of Sargassum variegatum(S.variegatum),Sargassum tenerrimum(S.tenerrimum)and Sargassum binderi occurring at Karachi coast against carbon tetrachloride(CCl_(4))and acetaminophen intoxication in rats.Methods:Sargassum species were collected at low tide from Buleji beach at Karachi coast.Effect of ethanol extracts of Sargassum spp.,on lipid parameter,serum glucose and kidney function was examined.Liver damage in rats was induced by CCl_(4) or acetaminophen.Rats were administered with ethanol extracts of S.tenerrimum,S.variegatum and Sargassum binderi at 200 mg/kg body weight daily for 14 days separately.Hepatotoxicity was determined in terms of cardiac and liver enzymes and other biochemical parameters.Results:S.variegatum showed highest activity by reducing the elevated level of hepatic enzymes,bilirubin,serum glucose,triglyceride with restoration of cholesterol.Urea and creatinine concentrations were also significantly(P<0.05)reduced as compared to acetaminophen intoxicated rats.S.tenerrimum and S.variegatum showed moderate activity against CCl_(4) hepatic toxicity.Conclusions:The protective role of S.variegatum against acetaminophen liver damage and its positive impact on disturbed lipid,glucose metabolism,kidney dysfunction and S.tenerrimum against CCl_(4) liver toxicity suggest that Sargassum species offer a non-chemical means for the treatment of toxicity mediated liver damage.