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能谱衰减曲线预测肺癌Ki-67表达:评估最佳keV及能谱曲线斜率 被引量:7
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作者 窦沛沛 赵恒亮 +8 位作者 王晨 刘忠啸 谢丽响 孟闫凯 胡春峰 荣玉涛 程广军 陈志成 徐凯 《临床放射学杂志》 CSCD 北大核心 2020年第12期2435-2440,共6页
目的探讨预测肺癌细胞增殖抗原标记物(Ki-67)表达的能谱CT最佳keV,以及不同能谱曲线斜率对预测效能的影响。方法回顾性分析43例原发性肺癌患者的CT数据,采用Siemens双源CT机型,完成动脉期和静脉期(峰值期)的能谱双期增强扫描。按Ki-67... 目的探讨预测肺癌细胞增殖抗原标记物(Ki-67)表达的能谱CT最佳keV,以及不同能谱曲线斜率对预测效能的影响。方法回顾性分析43例原发性肺癌患者的CT数据,采用Siemens双源CT机型,完成动脉期和静脉期(峰值期)的能谱双期增强扫描。按Ki-67表达将患者分为低风险组(Ki-67≤30%)和高风险组(Ki-67>30%),比较40~140 keV不同单能量图像区分两组患者的效能并获取最佳单能量图像。比较三组不同能谱曲线斜率(λ40~100,λ100~140和λ40~140)对预测Ki-67效能的影响。采用SPSS 22.0软件进行统计分析,P<0.05设为显著性差异值。结果在虚拟单光子能量图像中,动脉期40、50 keV及静脉期40、60、70 keV对应的CT值在Ki-67高、低表达组间有显著差异(P<0.05),其中静脉期40 keV是最佳单能量图像。动脉期三组能谱曲线斜率在Ki-67高、低表达组间均有显著性统计学差异(P<0.01),静脉期差异更显著(P=0.000,AUC分别为0.859、0.856、0.859)。结论能谱CT增强扫描静脉期40 keV单能量序列是预测肺癌Ki-67表达的最佳单能量序列,而能谱曲线斜率的不同未发现对预测结果产生明显偏倚。 展开更多
关键词 肺癌 细胞增殖抗原标记物 能谱CT kev 能谱曲线斜率
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无铅/少铅核辐射防护材料X射线铅当量测量研究
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作者 赵瑞 吴金杰 +4 位作者 刘博 汤显强 郭彬 吕雅竹 韩露 《核技术》 EI CAS CSCD 北大核心 2024年第1期42-48,共7页
新型无铅/少铅核辐射防护材料被越来越多地应用于军事领域,用于保障军队人员的安全和身体健康。基于目前军用核辐射防护服屏蔽性能无法准确测量以及溯源问题,为满足国际上主流军用核辐射防护服辐射性能评价需求,建立了用于防护服铅当量... 新型无铅/少铅核辐射防护材料被越来越多地应用于军事领域,用于保障军队人员的安全和身体健康。基于目前军用核辐射防护服屏蔽性能无法准确测量以及溯源问题,为满足国际上主流军用核辐射防护服辐射性能评价需求,建立了用于防护服铅当量测量装置,通过蒙特卡罗模拟和实验测量相结合方式建立了有效能量在130 keV条件下铅当量测量参考辐射质。采用窄束测量条件完成标准铅片的屏蔽性能测量,并对部分厂家生产的军用核辐射防护服材料进行了屏蔽效率与铅当量测试,铅当量测量结果的相对扩展不确定度为4.2%(k=2),为后续更多的军用核辐射防护材料的出厂前性能测试提供测量参考。 展开更多
关键词 核辐射防护材料 130 kev X射线 衰减率 铅当量
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The Technique of Genetic Transformation Mediated by keV Ion Beam 被引量:3
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作者 卞坡 余增亮 《Plasma Science and Technology》 SCIE EI CAS CSCD 2005年第1期2693-2696,共4页
The application of keV ion beam in life science started in China several decades ago. In 1986, researchers initially studied the mutagenic effect of ion beam, and successfully applied it to plant breeding. Nowadays, i... The application of keV ion beam in life science started in China several decades ago. In 1986, researchers initially studied the mutagenic effect of ion beam, and successfully applied it to plant breeding. Nowadays, ion beam implantation technique has been extensively applied to many biological fields. This paper mainly introduces one of its important applications: genetic transformation mediated by keV ion beam. 展开更多
关键词 ion-beam-mediated genetic transformation GENE total DNA kev ion beam
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利用新型CeBr_(3)探测器测量^(238)U活度研究 被引量:3
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作者 冯延强 王铁健 +4 位作者 杨龙泉 焦仓文 李必红 赵丹 王海洋 《核技术》 CAS CSCD 北大核心 2021年第3期34-39,共6页
将新型高分辨率CeBr_(3)闪烁体探测器应用于天然样品中^(238)U活度测量,利用实测谱数据分析了该新型探测器通过1 001 keV(^(234m)Pa)能量峰测量^(238)U活度的可行性,并与高分辨率HPGe半导体探测器进行了样品的测量对比。结果表明:该新... 将新型高分辨率CeBr_(3)闪烁体探测器应用于天然样品中^(238)U活度测量,利用实测谱数据分析了该新型探测器通过1 001 keV(^(234m)Pa)能量峰测量^(238)U活度的可行性,并与高分辨率HPGe半导体探测器进行了样品的测量对比。结果表明:该新型探测器可将1 001 keV与969 keV(^(238)UAc)区分开来,利用1 001 keV分析样品中^(238)U结果与HPGe一致,可用于室温条件下天然样品中^(238)U活度测量。 展开更多
关键词 CeBr_3探测器 ^(238)U 1001 kev 活度测量
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基于新型CeBr_(3)探测器井下γ能谱测量^(238)U关键技术研究 被引量:3
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作者 冯延强 王海洋 +2 位作者 王铁健 焦仓文 程纪星 《原子能科学技术》 EI CAS CSCD 北大核心 2021年第S02期422-428,共7页
为实现铀资源勘查中无需铀镭平衡修正、镭氡平衡修正,通过现场测井技术便可直接获取地层铀含量,研究了基于新型溴化铈(CeBr_(3))探测器的井下γ能谱测铀技术。针对井下地层铀矿体高强度γ射线的采集需求,设计了基于FPGA的快速数字化信... 为实现铀资源勘查中无需铀镭平衡修正、镭氡平衡修正,通过现场测井技术便可直接获取地层铀含量,研究了基于新型溴化铈(CeBr_(3))探测器的井下γ能谱测铀技术。针对井下地层铀矿体高强度γ射线的采集需求,设计了基于FPGA的快速数字化信号采集处理系统,实测获取了标准饱和模型井的γ射线谱,并分析了来自镭系214 Bi的934 keV及1120 keV对于1001 keV能峰的剥谱影响,构建了1001 keV能峰处铀镭比例系数,最后利用1001 keV能峰剥谱后的净面积计算了^(238) U含量,并在国家标准饱和模型井实测验证。结果表明,利用1001 keV能峰在各标准饱和模型井的^(238) U测量值与标称值相对偏差均在±10%以内。 展开更多
关键词 CeBr_(3)探测器 井下γ能谱 ^(238)U 1001 kev
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Development of 24 and 59 keV Filtered Neutron Beams for Neutron Capture Experiments at Dalat Research Reactor
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作者 Pham Ngoc Son Vuong Huu Tan +1 位作者 Phu Chi Hoa Tran Tuan Anh 《World Journal of Nuclear Science and Technology》 2014年第2期59-64,共6页
External filtered neutron beams have been developed at the horizontal radial channels No. 4 of Dalat research reactor. In the material composition of the neutron filters, the primary material components of Iron, Alumi... External filtered neutron beams have been developed at the horizontal radial channels No. 4 of Dalat research reactor. In the material composition of the neutron filters, the primary material components of Iron, Aluminum, Nickel and Vanadium are used to obtain the mono-energetic neutron beams of 24 and 59 keV, with low level of Gamma and slow neutron background. A computer code and Monte-Carlo simulation technique were applied to optimize the filter configurations and to deduce the neutron energy distributions in the filtered beams. A hydrogen-filled proton recoil detector and the activation method with Gold foils were used to measure the neutron energy spectrum and flux of each beam at sample position. The results of experimental neutron fluxes are 6.1 × 105 and 5.3 × 105 n/cm2/s for 24 and 59 keV beams, respectively. 展开更多
关键词 Research REACTOR Filtered NEUTRON 24 kev 59 kev
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Effect of annealing atmospheres on the scintillation properties of Ce^(3+)‑doped YAG nanoscintillator
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作者 Billel Zahra Lakhdar Guerbous +1 位作者 Hicham Bousbia‑salah Allaoua Boukerika 《Radiation Detection Technology and Methods》 CSCD 2023年第3期447-456,共10页
Background In this study,three sample detectors have been prepared by using cerium-activated YAG nanoscintillator(Y_(3)Al_(5)O_(12):Ce^(3+))synthesized by sol-gel method and heat-treat at 900°C for 2 h in differe... Background In this study,three sample detectors have been prepared by using cerium-activated YAG nanoscintillator(Y_(3)Al_(5)O_(12):Ce^(3+))synthesized by sol-gel method and heat-treat at 900°C for 2 h in different atmospheres such as vacuum,air and nitrogen.Purpose Many studies about YAG:Ce^(3+)single crystal have been carried out,but the material at the nanoscale remains not enough understood.The objective of the present paper is to investigate the effects of annealing atmosphere on the scintillation properties and identify the suitable atmosphere that allow to design radiation detectors with high scintillation efficiency.Methods In order to accurately assess the scintillation properties,the nanoscintillator sample powders have been designed as a detector,in which,preparation operations such as surface homogenization and efficiency coupling with photomultiplier tube(PMT)window were developed.The study was performed usingγ-rays 662 keV released from137Cs radioactive source,the bi-alkali GDB-4FF PMT was used as a photodetector.Nuclear instrumentation chain was set up in order to collect the pulse height spectra,NaI:Tl single-crystal scintillator was used as a reference detector to estimate the scintillation light yield.The delayed coincidence method was used for measuring the scintillation decay time of nanoscintillator sample detectors.Results The sample detector annealed at vacuum atmosphere exhibits the best scintillation properties,the scintillation light yield was estimated to be 14,600±3400 ph/MeV and the fast component in the scintillation decay was 90 ns.Conclusion The vacuum is the suitable atmosphere which allows the development of radiation detectors with high scintillation efficiency. 展开更多
关键词 Nanoscintillator YAG:Ce^(3+) Scintillation properties γ-rays 662 kev Photomultiplier tube Sample detectors Annealing atmosphere
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keV量级的N^+注入引起的氨基酸分子损伤 被引量:3
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作者 韩建伟 余增亮 《核技术》 CAS CSCD 北大核心 1999年第4期200-204,共5页
利用电子顺磁共振和红外光谱研究了keV级N+注入到几种固态氨基酸样品中引起的分子结构损伤。结果表明,这一注入导致了分子的严重损伤:分子结构解体,红外吸收普遍降低;产生了大量的碎片,其中自由基碎片的类型和数量随注入离子的剂... 利用电子顺磁共振和红外光谱研究了keV级N+注入到几种固态氨基酸样品中引起的分子结构损伤。结果表明,这一注入导致了分子的严重损伤:分子结构解体,红外吸收普遍降低;产生了大量的碎片,其中自由基碎片的类型和数量随注入离子的剂量发生显著变化;损伤碎片重组,形成了新的化学组合,表现出新的红外吸收峰。 展开更多
关键词 离子注入 注入损伤 氨基酸 分子损伤 kev 氮+
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井下直接铀定量γ能谱仪中铅屏蔽层的应用效果评价
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作者 冯延强 焦仓文 +2 位作者 乔宝强 杨龙泉 李必红 《铀矿地质》 CAS CSCD 2021年第3期485-491,共7页
研制井下直接铀定量γ能谱仪过程中,为降低信号采集的死时间及康普顿散射对于低能段γ能谱数据应用的影响,研究了新型CeBr3探测器组合铅屏蔽层技术,并针对0~3000 keV能量范围,从死时间、谱峰特征以及1001 keV能量特征峰在不同地层铀含... 研制井下直接铀定量γ能谱仪过程中,为降低信号采集的死时间及康普顿散射对于低能段γ能谱数据应用的影响,研究了新型CeBr3探测器组合铅屏蔽层技术,并针对0~3000 keV能量范围,从死时间、谱峰特征以及1001 keV能量特征峰在不同地层铀含量的响应等几方面对其应用效果进行了评价。研究结果表明在标准模型井中组合厚度为3 mm的铅屏蔽层时,在铀含量1.0%模型系统实测死时间由7.94%降低为3.73%;0~500 keV能量段的屏蔽计数占96%以上,高能段影响较小;1001 keV能量特征峰在不同铀含量时响应呈线性分布,达到预期目标。 展开更多
关键词 Γ能谱 直接铀定量 1001 kev 铅屏蔽 死时间
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EXPERIMENTAL EVIDENCE OF DINEUTRON EXISTENCE 被引量:1
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作者 ZHANG Yingji JIANG Dazhen YANG Jinqing 《Chinese Physics Letters》 SCIE CAS CSCD 1989年第3期113-116,共4页
The average binding energy of the dineutron virtual state was derived from the correlative spectrum of two protons in ^(2)H(d,^(2)p)^(2)n reaction,and from the p-p coincidence measurement the value is estimated to be ... The average binding energy of the dineutron virtual state was derived from the correlative spectrum of two protons in ^(2)H(d,^(2)p)^(2)n reaction,and from the p-p coincidence measurement the value is estimated to be about 210keV. 展开更多
关键词 COINCIDENCE SPECTRUM kev
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SEARCH FOR HEAVY NEUTRINOS IN ELECTRON CAPTURE
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作者 TANG Xiaowei LIU Nianqing 《Chinese Physics Letters》 SCIE CAS 1986年第11期489-492,共4页
We present the result of an experimental search for a heavy neutrino admixture in the electron capture process.The 95%confidence level upper limits from 0.02 to 0.04 are set for the mixing strength of heavy neutrinos ... We present the result of an experimental search for a heavy neutrino admixture in the electron capture process.The 95%confidence level upper limits from 0.02 to 0.04 are set for the mixing strength of heavy neutrinos in the neutrino mass range of 30keV to 90keV. 展开更多
关键词 process. MIXING kev
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用KeV单能电子束激发塑料闪烁体产生的光谱的特性的研究
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作者 陈永中 陈京 《研究生教育研究》 1992年第S1期39-42,共4页
用3KeV和5Kev的单能电子束激发塑料闪烁体,分别测量样品的透射和背向的发光光谱,背向发光光谱比透射发光光谱的短波成分丰富,通过分析,发现这种差异是闪烁体自吸收造成的。
关键词 闪烁体 kev 电子束能量 发光光谱 光致激发 光谱范围 单道分析器 定标器 能量分辨 深度分布
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Precise Determination of ^(40)Ti Mass by Measuring the ^(40)Sc Isospin Analogue State
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作者 LIU Wei-ping M.Hellstrom +14 位作者 R.Collatz J.Benlliure L.Chulkov D.Cortina Gil F.Farget H.Grawe Z.Hu N.Iwasa I.Reusen E.Roeckl M.Pfützner A.Piechaczek R.Raabe G.Vancraeynest A.Wohr 《Chinese Physics Letters》 SCIE CAS CSCD 2001年第11期1449-1451,共3页
The mass of 40 Ti has been determined by using the isobaric multiplet mass equation method. The experimental data of the 40Tiβ-decay were used to determine the level of the isospin analogue state of^( 40)Sc. The grou... The mass of 40 Ti has been determined by using the isobaric multiplet mass equation method. The experimental data of the 40Tiβ-decay were used to determine the level of the isospin analogue state of^( 40)Sc. The ground-state mass excess and the QEc value for 40 Ti were determined to be -9060 ± 12 keV and 11 466 ± 13keV, respectively. 展开更多
关键词 method DECAY kev
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Isotope Fractionation in the Sputtering of ^(63)Cu-^(65)Cu
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作者 ZHENG Liping CUI Fuzhai 《Chinese Physics Letters》 SCIE CAS CSCD 1995年第7期431-434,共4页
Under 2keV Xe ion bombardment of a ^(63)Cu69.1^(65)Cu30.9 isotope mixture,isotope fractionation difference between small and large polar emission angles,δ(15°)-δ(75°),was calculated by use of a dynamic Mon... Under 2keV Xe ion bombardment of a ^(63)Cu69.1^(65)Cu30.9 isotope mixture,isotope fractionation difference between small and large polar emission angles,δ(15°)-δ(75°),was calculated by use of a dynamic Monte Carlo program.Calculation results show that δ(15°)-δ(75°) is large at both the zero fluence and the high fluence,then it minimizes at a low fluence of 1.6x 10^(15) ions/cm^(2) between two fluence limits.An important cause of this minimum is that the surface composition gradient of ^(63)Cu maximiles at the fluence of 1.6x10^(15) ions /cm^(2). 展开更多
关键词 CALCULATION kev
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TEM Characterization of Helium Bubbles in T91 and MNHS Steels Implanted with 200 keV He Ions at Different Temperatures
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作者 王霁 高星 +14 位作者 王志光 魏孔芳 姚存峰 崔明焕 孙建荣 李炳生 庞立龙 朱亚滨 骆鹏 常海龙 张宏鹏 朱卉平 王栋 杜洋洋 谢二庆 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第7期102-105,共4页
Modified novel high silicon steel (MNHS, a newly developed reduced-activation martensitic alloy) and commercial alloy Tgl are implanted with 200 keV He2+ ions to a dose of 5 × 1020 ions/m2 at 300, 450 and 560~... Modified novel high silicon steel (MNHS, a newly developed reduced-activation martensitic alloy) and commercial alloy Tgl are implanted with 200 keV He2+ ions to a dose of 5 × 1020 ions/m2 at 300, 450 and 560~C. Transmission electron microscopy (TEM) is used to characterize the size and morphology of He bubbles. With the increase of the implantation temperature, TEM observations indicate that bubbles increase in size and the proportion of 'brick shaped' cuboid bubbles increases while the proportion of polyhedral bubbles decreases in both the steel samples. For the samples implanted at the same temperature, the average size of He bubbles in MNHS is smaller than that in T91. This might be due to the abundance of boundaries and precipitates in MNHS, which provide additional sites for the trapping of He atoms, thus reduce the susceptibility of MNHS to He embrittlement. 展开更多
关键词 TEM Characterization of Helium Bubbles in T91 and MNHS Steels Implanted with 200 kev He Ions at Different Temperatures
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^(99)Mo production via (p, f) Reaction on Natural Uranium
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作者 Wang Jieru Qin Zhi +3 位作者 Chen Dengsheng Huang Qinggang Wu Xiaolei Fan Fangli 《IMP & HIRFL Annual Report》 2019年第1期66-67,共2页
^(99)mTc is the most commonly used diagnostic medical radioisotope because of its short half-life(T1/2=6.01 h)and low β-energy(140.5 keV)[1].Generally,^(99)mTc is obtained from^(99)Mo decays by β-emission.
关键词 DECAY kev URANIUM
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SEARCH FOR AXIONS IN ORTHOPOSITRONIUM DECAY
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作者 TANG Xiaowei 《Chinese Physics Letters》 SCIE CAS 1987年第1期1-4,共4页
Monoenergetic peaks have been searched in the inclusive gamma ray spectrum from oPs decay.For axion massr 60keV to 970keV the 90%confidence level limits on the rabtio R of single gamma ray to three gamma ray decay fro... Monoenergetic peaks have been searched in the inclusive gamma ray spectrum from oPs decay.For axion massr 60keV to 970keV the 90%confidence level limits on the rabtio R of single gamma ray to three gamma ray decay from oPsr 6 ×10^(-4) to 6×10^(-5) without the assumption of the penetrating axions. 展开更多
关键词 DECAY ASSUMPTION kev
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LEVEL STRUCTURE OF ^(140)Ce FROM THE DECAY OF ^(140)La
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作者 LIU Yun-zuo WU Yao-dong +1 位作者 WANG Fang-ji ZHOU Jie-wen 《Chinese Physics Letters》 SCIE CAS 1985年第6期265-268,共4页
Gamma-gamma coincidence evidences are presented in this paper to confirm the existence of levels 3394.5keV and 3473.7keV in ^(140)Ce.The level 3520.8keV in ^(140)Ce should be discarded because of the identification of... Gamma-gamma coincidence evidences are presented in this paper to confirm the existence of levels 3394.5keV and 3473.7keV in ^(140)Ce.The level 3520.8keV in ^(140)Ce should be discarded because of the identification of the peak at 1924keV as a pure sum-peak of two strong gamma rays at 328kev and 1596keV. 展开更多
关键词 COINCIDENCE kev
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Single Electron Capture for Impact of Proton on H_(2)
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作者 WU Weimin GU Jian +2 位作者 WU Songmao LU Fuquan YANG Fujia 《Chinese Physics Letters》 SCIE CAS CSCD 1994年第8期484-487,共4页
The cross sections of electron capture for 3-10 keV proton traversing H_(2) were measured by using the‘growth rate’method.The experimental procedure is described.The experimental results are in good agreement with t... The cross sections of electron capture for 3-10 keV proton traversing H_(2) were measured by using the‘growth rate’method.The experimental procedure is described.The experimental results are in good agreement with the recommended data. 展开更多
关键词 METHOD ELECTRON kev
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Preliminary Study on Neutron Radiography with Several Hundred keV Fast Neutrons
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作者 LI Hang ZOU Yu-Bin +2 位作者 LU Yuan-Rong GUO Zhi-Yu TANG Guo-You 《Chinese Physics Letters》 SCIE CAS CSCD 2012年第11期227-230,共4页
Several hundred keV fast neutron radiography(HKFNR)can be a complementary technique to common thermal neutron radiography(TNR)and several MeV fast neutron radiography(MFNR).We tested HKFNR on a 4.5 MV Van de Graaff ac... Several hundred keV fast neutron radiography(HKFNR)can be a complementary technique to common thermal neutron radiography(TNR)and several MeV fast neutron radiography(MFNR).We tested HKFNR on a 4.5 MV Van de Graaff accelerator,and the experimental results show that the spatial resolution of this technique is better than MFNR and close to TNR.Several hundred keV fast neutrons can penetrate some thermal neutron absorbers such as Cd,and it is feasible to investigate its use on some materials which are transparent to cold/thermal neutrons,such as aluminum,using this technique. 展开更多
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