<strong>Background: </strong><span style="font-family:""><span style="font-family:Verdana;">We previously reported independent predictors of intraoperative and postoper...<strong>Background: </strong><span style="font-family:""><span style="font-family:Verdana;">We previously reported independent predictors of intraoperative and postoperative morbidity. These were age, American Society of Anesthesiologists Score (ASA), emergency situations, surgery and transfusion. ASA was the independent predictor of mortality. We conducted a secondary analysis of this previous retrospective study in patients who underwent exploratory laparotomy and intestinal resection. </span><b><span style="font-family:Verdana;">Objectives: </span></b><span style="font-family:Verdana;">T</span></span><span style="font-family:Verdana;">he </span><span style="font-family:Verdana;">o</span><span style="font-family:Verdana;">bjective was to</span><span style="font-family:""><span style="font-family:Verdana;"> describe intraoperative and postoperative outcomes in patients who underwent exploratory laparotomy and intestinal resection in the initial study and to present a research protocol for intraoperative and postoperative optimization. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Secondary analysis of the initial study</span></span><span style="font-family:Verdana;"> was used</span><span style="font-family:""><span style="font-family:Verdana;">. The Ethics Committee approved the study. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> There were 54 patients with a median age of 15.5</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">[</span><span style="font-family:Verdana;">0</span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:Verdana;">172</span><span style="font-family:Verdana;">]</span><span style="font-family:Verdana;"> months. Thirty-seven (68.5%) patients underwent intestinal resection, nine (16.7%) underwent exploratory laparotomy, and eight (16.8%) underwent laparotomy for vol展开更多
<strong>Background:</strong> Neuroblastoma is the most common tumor in children. Anesthetic management can be challenging due to the localization and catecholamine-secreting characteristics of the tumor. W...<strong>Background:</strong> Neuroblastoma is the most common tumor in children. Anesthetic management can be challenging due to the localization and catecholamine-secreting characteristics of the tumor. We undertook a secondary analysis in a previous study to describe patients who underwent neuroblastoma resection. <strong>Objective:</strong> To describe intraoperative and postoperative outcomes in patients who underwent neuroblastoma resection and to propose optimal intraoperative management for postoperative outcome improvement. <strong>Methods:</strong> This was a secondary analysis of children who underwent neuroblastoma resection in the initial retrospective study. <strong>Results:</strong> There were 16 patients with a mean age of 39.3 ± 22.1 months. Seven (43.8%) patients presented with intraoperative or postoperative complications. One (6.3%) patient had intraoperative broncho-laryngospasm and difficult intubation. Two (12.5%) patients had intraoperative hemorrhagic shock. One patient (6.3%) had postoperative renal failure. Two patients (12.5%) had postoperative respiratory failure, and 3 (18.8%) patients had postoperative cardiocirculatory failure. One (6.3%) had postoperative pulmonary sepsis and septicemia. Thirteen (81.3%) patients were intraoperatively transfused. There was no in-hospital mortality. <strong>Conclusion:</strong> In this cohort, 43.8% of the patients had intraoperative and or postoperative complications in terms of organ dysfunction or sepsis. 81.3% of the patients received intraoperative transfusion. Neuroblastoma surgery can be a challenging situation where cardiovascular instability, high blood loss and transfusion requirements can be encountered. Consequently, preoperative preparation and optimal intraoperative management with validated tools in children could be necessary for a better postoperative outcome in this surgical setting.展开更多
文摘<strong>Background: </strong><span style="font-family:""><span style="font-family:Verdana;">We previously reported independent predictors of intraoperative and postoperative morbidity. These were age, American Society of Anesthesiologists Score (ASA), emergency situations, surgery and transfusion. ASA was the independent predictor of mortality. We conducted a secondary analysis of this previous retrospective study in patients who underwent exploratory laparotomy and intestinal resection. </span><b><span style="font-family:Verdana;">Objectives: </span></b><span style="font-family:Verdana;">T</span></span><span style="font-family:Verdana;">he </span><span style="font-family:Verdana;">o</span><span style="font-family:Verdana;">bjective was to</span><span style="font-family:""><span style="font-family:Verdana;"> describe intraoperative and postoperative outcomes in patients who underwent exploratory laparotomy and intestinal resection in the initial study and to present a research protocol for intraoperative and postoperative optimization. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Secondary analysis of the initial study</span></span><span style="font-family:Verdana;"> was used</span><span style="font-family:""><span style="font-family:Verdana;">. The Ethics Committee approved the study. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> There were 54 patients with a median age of 15.5</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">[</span><span style="font-family:Verdana;">0</span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:Verdana;">172</span><span style="font-family:Verdana;">]</span><span style="font-family:Verdana;"> months. Thirty-seven (68.5%) patients underwent intestinal resection, nine (16.7%) underwent exploratory laparotomy, and eight (16.8%) underwent laparotomy for vol
文摘<strong>Background:</strong> Neuroblastoma is the most common tumor in children. Anesthetic management can be challenging due to the localization and catecholamine-secreting characteristics of the tumor. We undertook a secondary analysis in a previous study to describe patients who underwent neuroblastoma resection. <strong>Objective:</strong> To describe intraoperative and postoperative outcomes in patients who underwent neuroblastoma resection and to propose optimal intraoperative management for postoperative outcome improvement. <strong>Methods:</strong> This was a secondary analysis of children who underwent neuroblastoma resection in the initial retrospective study. <strong>Results:</strong> There were 16 patients with a mean age of 39.3 ± 22.1 months. Seven (43.8%) patients presented with intraoperative or postoperative complications. One (6.3%) patient had intraoperative broncho-laryngospasm and difficult intubation. Two (12.5%) patients had intraoperative hemorrhagic shock. One patient (6.3%) had postoperative renal failure. Two patients (12.5%) had postoperative respiratory failure, and 3 (18.8%) patients had postoperative cardiocirculatory failure. One (6.3%) had postoperative pulmonary sepsis and septicemia. Thirteen (81.3%) patients were intraoperatively transfused. There was no in-hospital mortality. <strong>Conclusion:</strong> In this cohort, 43.8% of the patients had intraoperative and or postoperative complications in terms of organ dysfunction or sepsis. 81.3% of the patients received intraoperative transfusion. Neuroblastoma surgery can be a challenging situation where cardiovascular instability, high blood loss and transfusion requirements can be encountered. Consequently, preoperative preparation and optimal intraoperative management with validated tools in children could be necessary for a better postoperative outcome in this surgical setting.
