国际癌症研究机构(International Agency for Research on Cancer,IARC)于2015年3月发布评估报告将草甘膦列入"2A"类致癌物,自此引发了关于草甘膦究竟是否具有致癌性的争议。之后,美国环保署(Environmental Protection Agency...国际癌症研究机构(International Agency for Research on Cancer,IARC)于2015年3月发布评估报告将草甘膦列入"2A"类致癌物,自此引发了关于草甘膦究竟是否具有致癌性的争议。之后,美国环保署(Environmental Protection Agency,EPA)再次对草甘膦进行了致癌性评估,认为草甘膦"不太可能致癌"。基于草甘膦的安全性一直备受关注与热议,文章总结了IARC与EPA两机构评估报告中所参照的研究数据,从流行病学研究、动物实验研究和其他致癌性证据三个方面入手,重点描述了其中具有阳性结论的数据,旨在客观反映两机构作出不同评估结论的原因主要在于他们所引用的研究数据存在差异。展开更多
国际癌症研究机构(International Agency for Research on Cancer,IARC)把镍化合物定为Ⅰ类致癌物。国际劳工组织(International Labour Organization,ILO)也把镍化合物列为职业性癌症的致癌因素。目前我国正在修订《职业病分类和目录》...国际癌症研究机构(International Agency for Research on Cancer,IARC)把镍化合物定为Ⅰ类致癌物。国际劳工组织(International Labour Organization,ILO)也把镍化合物列为职业性癌症的致癌因素。目前我国正在修订《职业病分类和目录》,镍化合物所致癌症也可能列入法定职业病。2022年ILO出版的《职业病诊断与接触标准》对镍化合物的致病特征、职业接触情况、主要健康影响、诊断标准及预防关键措施等内容做了详细论述,本文主要对其内容进行介绍,为我国制定相关标准提供依据。展开更多
In the early 1900 s, numerous seminal publications reported that high rates of cancer occurred in certain occupations. During this period, work with infectious agents produced only meager results which seemed irreleva...In the early 1900 s, numerous seminal publications reported that high rates of cancer occurred in certain occupations. During this period, work with infectious agents produced only meager results which seemed irrelevant to humans. Then in the 1980 s ground breaking evidence began to emerge that a variety of viruses also cause cancer in humans. There is now sufficient evidence of carcinogenicity in humans for human T-cell lymphotrophic virus, human immunodeficiency virus, hepatitis B virus, hepatitis C virus, human papillomavirus, Epstein-Barr virus, and human herpes virus 8 according to the International Agency for Research on Cancer(IARC). Many other causes of cancer have also been identified by the IARC, which include: Sunlight, tobacco, pharmaceuticals, hormones, alcohol, parasites, fungi, bacteria, salted fish, wood dust, and herbs. The World Cancer Research Fund and the American Institute for Cancer Research have determined additional causes of cancer, which include beta carotene, red meat, processed meats, low fibre diets, not breast feeding, obesity, increased adult height and sedentary lifestyles. In brief, a historical review of the discoveries of the causes of human cancer is presented with extended discussions of the difficulties encountered in identifying viral causes of cancer.展开更多
世界卫生组织下属机构国际癌症研究中心（International Agency for Research on Cancer,IARC）公布的《IARC关于致人类癌症危险性评价专题论文集》[1]是最具权威的对人类致癌性评价的专著。危险性评价因素包括化学物、环境因子和类别...世界卫生组织下属机构国际癌症研究中心（International Agency for Research on Cancer,IARC）公布的《IARC关于致人类癌症危险性评价专题论文集》[1]是最具权威的对人类致癌性评价的专著。危险性评价因素包括化学物、环境因子和类别、混合物、暴露环境、物理因子、生物因子以及生活行为方式等,展开更多
文摘国际癌症研究机构(International Agency for Research on Cancer,IARC)于2015年3月发布评估报告将草甘膦列入"2A"类致癌物,自此引发了关于草甘膦究竟是否具有致癌性的争议。之后,美国环保署(Environmental Protection Agency,EPA)再次对草甘膦进行了致癌性评估,认为草甘膦"不太可能致癌"。基于草甘膦的安全性一直备受关注与热议,文章总结了IARC与EPA两机构评估报告中所参照的研究数据,从流行病学研究、动物实验研究和其他致癌性证据三个方面入手,重点描述了其中具有阳性结论的数据,旨在客观反映两机构作出不同评估结论的原因主要在于他们所引用的研究数据存在差异。
文摘国际癌症研究机构(International Agency for Research on Cancer,IARC)把镍化合物定为Ⅰ类致癌物。国际劳工组织(International Labour Organization,ILO)也把镍化合物列为职业性癌症的致癌因素。目前我国正在修订《职业病分类和目录》,镍化合物所致癌症也可能列入法定职业病。2022年ILO出版的《职业病诊断与接触标准》对镍化合物的致病特征、职业接触情况、主要健康影响、诊断标准及预防关键措施等内容做了详细论述,本文主要对其内容进行介绍,为我国制定相关标准提供依据。
文摘In the early 1900 s, numerous seminal publications reported that high rates of cancer occurred in certain occupations. During this period, work with infectious agents produced only meager results which seemed irrelevant to humans. Then in the 1980 s ground breaking evidence began to emerge that a variety of viruses also cause cancer in humans. There is now sufficient evidence of carcinogenicity in humans for human T-cell lymphotrophic virus, human immunodeficiency virus, hepatitis B virus, hepatitis C virus, human papillomavirus, Epstein-Barr virus, and human herpes virus 8 according to the International Agency for Research on Cancer(IARC). Many other causes of cancer have also been identified by the IARC, which include: Sunlight, tobacco, pharmaceuticals, hormones, alcohol, parasites, fungi, bacteria, salted fish, wood dust, and herbs. The World Cancer Research Fund and the American Institute for Cancer Research have determined additional causes of cancer, which include beta carotene, red meat, processed meats, low fibre diets, not breast feeding, obesity, increased adult height and sedentary lifestyles. In brief, a historical review of the discoveries of the causes of human cancer is presented with extended discussions of the difficulties encountered in identifying viral causes of cancer.
文摘世界卫生组织下属机构国际癌症研究中心（International Agency for Research on Cancer,IARC）公布的《IARC关于致人类癌症危险性评价专题论文集》[1]是最具权威的对人类致癌性评价的专著。危险性评价因素包括化学物、环境因子和类别、混合物、暴露环境、物理因子、生物因子以及生活行为方式等,
