随着LED照明向普通照明领域进军,作为LED电源重要组成部分的高频电压器,体积小、功耗低、电磁辐射小、工作频率高,成为其主要的性能指标。针对此目的,对LED开关电源反激变压器的设计进行研究,结合实际采用面积乘积法设计一款单端反激式...随着LED照明向普通照明领域进军,作为LED电源重要组成部分的高频电压器,体积小、功耗低、电磁辐射小、工作频率高,成为其主要的性能指标。针对此目的,对LED开关电源反激变压器的设计进行研究,结合实际采用面积乘积法设计一款单端反激式高频变压器,运用变压器电感电流断续的工作模式使得变压器的体积大大减小,同时在很大程度上也减小了变压器的电磁干扰辐射。通过3 W LED电源的制作测试实验对设计方案进行验证,结果证明了设计方案的可行性,达到了预期的效果。展开更多
Chronic intermittent hypobaric hypoxia(CIHH)is known to have an anti-hypertensive effect, which might be related to modulation of the baroreflex in rats with renal vascular hypertension(RVH). In this study, RVH was in...Chronic intermittent hypobaric hypoxia(CIHH)is known to have an anti-hypertensive effect, which might be related to modulation of the baroreflex in rats with renal vascular hypertension(RVH). In this study, RVH was induced by the 2-kidney-1-clip method(2 K1 C) in adult male Sprague-Dawley rats. The rats were then treated with hypobaric hypoxia simulating 5000 m altitude for 6 h/day for 28 days. The arterial blood pressure(ABP), heart rate(HR), and renal sympathetic nerve activity(RSNA) were measured before and after microinjection of L-arginine into the nucleus tractus solitarii(NTS) in anesthetized rats.Evoked excitatory postsynaptic currents(eEPSCs) and spontaneous EPSCs(sEPSCs) were recorded in anterogradely-labeled NTS neurons receiving baroreceptor afferents. We measured the protein expression of neuronal nitric oxide synthase(nNOS) and endothelial NOS(eNOS) in the NTS. The results showed that the ABP in RVH rats was significantly lower after CIHH treatment. The inhibition of ABP, HR, and RSNA induced by L-arginine was less in RVH rats than in sham rats, and greater in the CIHHtreated RVH rats than the untreated RVH rats. The eEPSC amplitude in NTS neurons receiving baroreceptor afferents was lower in the RVH rats than in the sham rats and recovered after CIHH. The protein expression of nNOS and e NOS in the NTS was lower in the RVH rats than in the sham rats and this decrease was reversed by CIHH. In short, CIHH treatment decreases ABP in RVH rats via upregulating NOS expression in the NTS.展开更多
文摘随着LED照明向普通照明领域进军,作为LED电源重要组成部分的高频电压器,体积小、功耗低、电磁辐射小、工作频率高,成为其主要的性能指标。针对此目的,对LED开关电源反激变压器的设计进行研究,结合实际采用面积乘积法设计一款单端反激式高频变压器,运用变压器电感电流断续的工作模式使得变压器的体积大大减小,同时在很大程度上也减小了变压器的电磁干扰辐射。通过3 W LED电源的制作测试实验对设计方案进行验证,结果证明了设计方案的可行性,达到了预期的效果。
基金supported by the National Natural Science Foundation of China(31071002,31271223,31671184,and 81800308)the National Basic Research Development Program of China(2012CB518200)the Natural Science Foundation of Hebei Province(C2012206001),China
文摘Chronic intermittent hypobaric hypoxia(CIHH)is known to have an anti-hypertensive effect, which might be related to modulation of the baroreflex in rats with renal vascular hypertension(RVH). In this study, RVH was induced by the 2-kidney-1-clip method(2 K1 C) in adult male Sprague-Dawley rats. The rats were then treated with hypobaric hypoxia simulating 5000 m altitude for 6 h/day for 28 days. The arterial blood pressure(ABP), heart rate(HR), and renal sympathetic nerve activity(RSNA) were measured before and after microinjection of L-arginine into the nucleus tractus solitarii(NTS) in anesthetized rats.Evoked excitatory postsynaptic currents(eEPSCs) and spontaneous EPSCs(sEPSCs) were recorded in anterogradely-labeled NTS neurons receiving baroreceptor afferents. We measured the protein expression of neuronal nitric oxide synthase(nNOS) and endothelial NOS(eNOS) in the NTS. The results showed that the ABP in RVH rats was significantly lower after CIHH treatment. The inhibition of ABP, HR, and RSNA induced by L-arginine was less in RVH rats than in sham rats, and greater in the CIHHtreated RVH rats than the untreated RVH rats. The eEPSC amplitude in NTS neurons receiving baroreceptor afferents was lower in the RVH rats than in the sham rats and recovered after CIHH. The protein expression of nNOS and e NOS in the NTS was lower in the RVH rats than in the sham rats and this decrease was reversed by CIHH. In short, CIHH treatment decreases ABP in RVH rats via upregulating NOS expression in the NTS.
