Imino Diels-Alder reaction of imines with 2,3-dihydrofuran or 3,4-dihydro-2H-pyran proceeded smoothly in the presence of a catalytic amount (0.5 mol %) of ytterbium triflate to afford furo[3,2-c]- and pyrano[3,2-c] q... Imino Diels-Alder reaction of imines with 2,3-dihydrofuran or 3,4-dihydro-2H-pyran proceeded smoothly in the presence of a catalytic amount (0.5 mol %) of ytterbium triflate to afford furo[3,2-c]- and pyrano[3,2-c] quinolines conveniently in high yield.展开更多
A simple synthesis of medicinally important cis-2-methyl-4-azapan-2-one-1,2,3,4-tetrahydroquinolines/cis-9- （2-methyl-l,2,3,4-tetrahydroquinolin-4-yl）-9H-carbazole was reported. Multicomponent one pot synthesis with...A simple synthesis of medicinally important cis-2-methyl-4-azapan-2-one-1,2,3,4-tetrahydroquinolines/cis-9- （2-methyl-l,2,3,4-tetrahydroquinolin-4-yl）-9H-carbazole was reported. Multicomponent one pot synthesis with ani- lines and N-vinylcaprolactam/N-vinyl carbazole via imino Diels-Alder reaction by using antimony trichloride as catalyst and acetonitrile as solvent was employed. NMR technique （2D） was used to study the regio- and stereo- chemistry of newly synthesized compounds. The cis diastereo-selectivity of the products was predicted by COSY and NOESY studies.展开更多
Quinazoline derivatives were synthesized fromα-iminoesters via a cascade imino-Diels-Alder and then oxidation reaction catalyzed with CuBr_2.This method provided a new strategy for preparing quinazoline derivatives w...Quinazoline derivatives were synthesized fromα-iminoesters via a cascade imino-Diels-Alder and then oxidation reaction catalyzed with CuBr_2.This method provided a new strategy for preparing quinazoline derivatives which may be useful in the synthesis of heterocyclic intermediates.展开更多
基金Project supported by the National Natural Science Fondation of China and Postdoctoral Foundation of China.
文摘 Imino Diels-Alder reaction of imines with 2,3-dihydrofuran or 3,4-dihydro-2H-pyran proceeded smoothly in the presence of a catalytic amount (0.5 mol %) of ytterbium triflate to afford furo[3,2-c]- and pyrano[3,2-c] quinolines conveniently in high yield.
文摘A simple synthesis of medicinally important cis-2-methyl-4-azapan-2-one-1,2,3,4-tetrahydroquinolines/cis-9- （2-methyl-l,2,3,4-tetrahydroquinolin-4-yl）-9H-carbazole was reported. Multicomponent one pot synthesis with ani- lines and N-vinylcaprolactam/N-vinyl carbazole via imino Diels-Alder reaction by using antimony trichloride as catalyst and acetonitrile as solvent was employed. NMR technique （2D） was used to study the regio- and stereo- chemistry of newly synthesized compounds. The cis diastereo-selectivity of the products was predicted by COSY and NOESY studies.
基金the financial support from National Natural Science Foundation of China(No.20972198).
文摘Quinazoline derivatives were synthesized fromα-iminoesters via a cascade imino-Diels-Alder and then oxidation reaction catalyzed with CuBr_2.This method provided a new strategy for preparing quinazoline derivatives which may be useful in the synthesis of heterocyclic intermediates.
