Objective To isolate and identify bioactive constituents from the stem barks of I//icium difengpi. Methods The chemical constituents were isolated and purified by repeated silica gel, Sephadex LH-20, recrystallization...Objective To isolate and identify bioactive constituents from the stem barks of I//icium difengpi. Methods The chemical constituents were isolated and purified by repeated silica gel, Sephadex LH-20, recrystallization, and preparative HPLC techniques. The structures of the compounds were identified on the basis of spectral data including NMR, MS, and IR. Results Two sesquiterpene lactones, majucin （I） and anisatin （2）, two steroids, l^-sitosterol （3） and daucosterol （4）, three carboxylic acids, 2-ethyldecanoic acid （5）, shikimic acid （6）, and 3,4-dihydrobenzoic acid （7）, and a flavonoid, quercetin （8）, were successively isolated from the stem barks of L difengpL Conclusion Apart from compound 3, other seven compounds are reported in this plant for the first time. The results suggested that the current studies on L difengpi is still far from being well known and therefore more studies need to be done for better understanding of this plant.展开更多
文摘Objective To isolate and identify bioactive constituents from the stem barks of I//icium difengpi. Methods The chemical constituents were isolated and purified by repeated silica gel, Sephadex LH-20, recrystallization, and preparative HPLC techniques. The structures of the compounds were identified on the basis of spectral data including NMR, MS, and IR. Results Two sesquiterpene lactones, majucin （I） and anisatin （2）, two steroids, l^-sitosterol （3） and daucosterol （4）, three carboxylic acids, 2-ethyldecanoic acid （5）, shikimic acid （6）, and 3,4-dihydrobenzoic acid （7）, and a flavonoid, quercetin （8）, were successively isolated from the stem barks of L difengpL Conclusion Apart from compound 3, other seven compounds are reported in this plant for the first time. The results suggested that the current studies on L difengpi is still far from being well known and therefore more studies need to be done for better understanding of this plant.
