在超声作用下,假设亚油酸共轭反应为不可逆恒容反应,且反应一步完成的基础上,研究了碱催化亚油酸共轭反应的动力学。考察了反应物与催化剂的浓度、超声声强、温度对共轭反应速率的影响,并通过理论推导与试验拟合得到了各因素对反应速率...在超声作用下,假设亚油酸共轭反应为不可逆恒容反应,且反应一步完成的基础上,研究了碱催化亚油酸共轭反应的动力学。考察了反应物与催化剂的浓度、超声声强、温度对共轭反应速率的影响,并通过理论推导与试验拟合得到了各因素对反应速率常数影响的数学模型。结果表明,在超声作用下,碱催化亚油酸共轭反应符合宏观一级动力学特征;超声声强、反应物初始浓度、温度及催化剂浓度对反应速率的影响较大。在超声作用下反应的表观活化能为112.1 k J/mol,与常规相比,有所降低,这说明,超声作用可以使共轭反应进行得更快。试验同时显示,所得到的模型对试验结果的预测非常好,可用于超声作用下亚油酸共轭反应结果的预测。展开更多
Linoleoyl benzotriazole was synthesized from linoleic acid and benzotriazole by means of dicyclohexylcarbodiimide coupling method and characterized by FT-IR and 1H NMR.Linoleoyl insulin was prepared by chemical modifi...Linoleoyl benzotriazole was synthesized from linoleic acid and benzotriazole by means of dicyclohexylcarbodiimide coupling method and characterized by FT-IR and 1H NMR.Linoleoyl insulin was prepared by chemical modification of insulin with linoleoyl benzotriazole without using any specific protecting group.MALDI-TOF-MS analysis showed that the modification of insulin was successful and the monoacylated insulin was the major product.A little diacylated insulin was observed and no triacylated insulin was detected.展开更多
文摘在超声作用下,假设亚油酸共轭反应为不可逆恒容反应,且反应一步完成的基础上,研究了碱催化亚油酸共轭反应的动力学。考察了反应物与催化剂的浓度、超声声强、温度对共轭反应速率的影响,并通过理论推导与试验拟合得到了各因素对反应速率常数影响的数学模型。结果表明,在超声作用下,碱催化亚油酸共轭反应符合宏观一级动力学特征;超声声强、反应物初始浓度、温度及催化剂浓度对反应速率的影响较大。在超声作用下反应的表观活化能为112.1 k J/mol,与常规相比,有所降低,这说明,超声作用可以使共轭反应进行得更快。试验同时显示,所得到的模型对试验结果的预测非常好,可用于超声作用下亚油酸共轭反应结果的预测。
文摘Linoleoyl benzotriazole was synthesized from linoleic acid and benzotriazole by means of dicyclohexylcarbodiimide coupling method and characterized by FT-IR and 1H NMR.Linoleoyl insulin was prepared by chemical modification of insulin with linoleoyl benzotriazole without using any specific protecting group.MALDI-TOF-MS analysis showed that the modification of insulin was successful and the monoacylated insulin was the major product.A little diacylated insulin was observed and no triacylated insulin was detected.
