AIM: To study gastric mucosal interleukine-8 (IL-8) mRNA expression, the cytotoxin-associated gene A (cagA) mutation, and serum pepsinogen (PG)?I/II ratio related risk in Thai gastric cancer.METHODS: There were consen...AIM: To study gastric mucosal interleukine-8 (IL-8) mRNA expression, the cytotoxin-associated gene A (cagA) mutation, and serum pepsinogen (PG)?I/II ratio related risk in Thai gastric cancer.METHODS: There were consent 134 Thai non-cancer volunteers who underwent endoscopic narrow band imaging examination, and 86 Thais advance gastric cancer patients who underwent endoscopic mucosal biopsies and gastric surgery. Tissue samples were taken by endoscopy with 3 points biopsies. The serum PG?I, II, and Helicobacter pylori (H. pylori) immunoglobulin G (IgG) antibody for H. pylori were tested by enzyme-linked immunosorbent assay technique. The histopathology description of gastric cancer and non-cancer with H. pylori detection was defined with modified Sydney Score System. Gastric mucosal tissue H. pylori DNA was extracted and genotyped for cagA mutation. Tissue IL-8 and cyclooxygenase-2 (COX-2) mRNA expression were conducted by real time relative quantitation polymerase chain reaction. From 17 Japanese advance gastric cancer and 12 benign gastric tissue samples, all were tested for genetic expression with same methods as well as Thai gastric mucosal tissue samples. The multivariate analysis was used for the risk study. Correlation and standardized t-test were done for quantitative data, P value < 0.05 was considered as a statistically significant.RESULTS: There is a high non cagA gene of 86.8 per cent in Thai gastric cancer although there are high yields of the East Asian type in the positive cagA. The H. pylori infection prevalence in this study is reported by combined histopathology and H. pylori IgG antibody test with 77.1% and 97.4% of sensitivity and specificity, respectively. The serum PG?I/II ratio in gastric cancer is significantly lower than in the non-cancer group, P = 0.045. The serum PG?I/II ratio of less than 3.0 and IL-8 mRNA expression ≥ 100 or log10 ≥ 2 are significant cut off risk differences between Thai cancer and non-cancer, P = 0.03 and P < 0.001, respectively. There is a significantly lower PG展开更多
In order to enhance the bearing capacity of structural components,save materials,and reduce cost,a glued laminated timber(glulam)I-beam that is theoretically suitable for engineering application was proposed.In this s...In order to enhance the bearing capacity of structural components,save materials,and reduce cost,a glued laminated timber(glulam)I-beam that is theoretically suitable for engineering application was proposed.In this study,18 glulam specimens were fabricated using larch dimension lumber and resorcinol-formaldehyde resin.Four-point bending tests were carried out to compare the ultimate bearing capacity,strain,and deflection of various specimens.The results showed that:(1)The typical failure mode at bending is the web shear failure parallel to grain.Before the failure,cracks and sounds appear at the beam web,which represent the sudden brittle failure.(2)The cross-sectional strain of glulam beam changed linearly with the beam height,indicating that the plane section assumption was basically established.(3)Stiffener could improve the initial flexural stiffness of glulam beam,which experiences an increase of 28.21%.Larger the shear span ratio,smaller the initial flexural stiffness.The initial flexural stiffness improves by 10-23.5%with the increase in the thickness of the lower flange.(4)The effects of stiffener and shear-span ratio on shear strength are relatively significant.After the stiffeners are set at the support and the loading point in pairs,the shear strength of the glulam beam increases by 15.05%averagely.With the increase in the shear-span ratio,the shearing strength of the glulam I-beam gradually reduces.The equation of the shearing strength with the shear span ratio is obtained,which is shown by high fitting precision.(5)The shear strength correlation,as proposed by Soltis and Rammer,is suitable not only for rectangular beams,but also for glulam I-beams.展开更多
在认真研究LOCO-I算法的基础上,深入分析了失真控制参数Near对图像压缩比和重建质量的影响,通过对该算法中的Near进行实时动态调整,实现了对图像近无损压缩的压缩比控制,进而可以根据需求来控制图片大小进行压缩。仿真结果表明,提出的...在认真研究LOCO-I算法的基础上,深入分析了失真控制参数Near对图像压缩比和重建质量的影响,通过对该算法中的Near进行实时动态调整,实现了对图像近无损压缩的压缩比控制,进而可以根据需求来控制图片大小进行压缩。仿真结果表明,提出的压缩比控制方案收敛性较好,输出码流稳定,在满足目标压缩比时重建图像质量较原一阶压缩比控制方案提高了0.5 d B左右。展开更多
This paper analyses the changing rule of indoor ozone concentration and its influencing factors.A formula of indoor-outdoor concentration ratio(I/O ratio) was deduced based on the indoor ozone mass-balance equation.Th...This paper analyses the changing rule of indoor ozone concentration and its influencing factors.A formula of indoor-outdoor concentration ratio(I/O ratio) was deduced based on the indoor ozone mass-balance equation.The ozone I/O ratio in different kinds of buildings was studied.Results show that I/O ratio is much related to air-exchange rate,which is well compatible with the theoretical calculation results.展开更多
基金Supported by JSPS Ronpaku (Dissertation PhD) program (No.NRCT 10726) award by Japan Society for the Promotion of Scince and in collaboration with Kobe University School of Medicine,Kobe,JapanJSPS Asian CORE Program 2012,Nippon Medical Schoolthe Faculty of Medicine,Chiang Mai University,Chiang Mai,Thailand (in part)
文摘AIM: To study gastric mucosal interleukine-8 (IL-8) mRNA expression, the cytotoxin-associated gene A (cagA) mutation, and serum pepsinogen (PG)?I/II ratio related risk in Thai gastric cancer.METHODS: There were consent 134 Thai non-cancer volunteers who underwent endoscopic narrow band imaging examination, and 86 Thais advance gastric cancer patients who underwent endoscopic mucosal biopsies and gastric surgery. Tissue samples were taken by endoscopy with 3 points biopsies. The serum PG?I, II, and Helicobacter pylori (H. pylori) immunoglobulin G (IgG) antibody for H. pylori were tested by enzyme-linked immunosorbent assay technique. The histopathology description of gastric cancer and non-cancer with H. pylori detection was defined with modified Sydney Score System. Gastric mucosal tissue H. pylori DNA was extracted and genotyped for cagA mutation. Tissue IL-8 and cyclooxygenase-2 (COX-2) mRNA expression were conducted by real time relative quantitation polymerase chain reaction. From 17 Japanese advance gastric cancer and 12 benign gastric tissue samples, all were tested for genetic expression with same methods as well as Thai gastric mucosal tissue samples. The multivariate analysis was used for the risk study. Correlation and standardized t-test were done for quantitative data, P value < 0.05 was considered as a statistically significant.RESULTS: There is a high non cagA gene of 86.8 per cent in Thai gastric cancer although there are high yields of the East Asian type in the positive cagA. The H. pylori infection prevalence in this study is reported by combined histopathology and H. pylori IgG antibody test with 77.1% and 97.4% of sensitivity and specificity, respectively. The serum PG?I/II ratio in gastric cancer is significantly lower than in the non-cancer group, P = 0.045. The serum PG?I/II ratio of less than 3.0 and IL-8 mRNA expression ≥ 100 or log10 ≥ 2 are significant cut off risk differences between Thai cancer and non-cancer, P = 0.03 and P < 0.001, respectively. There is a significantly lower PG
基金supported by the Natural Science Foundation of Jiang-su Province(Grant No.BK20181402)the National Natural Science Foundation of China(Grant No.51878354)+2 种基金a Project Funded by the National First-class Disciplines(PNFD)a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)a Project Funded by the Co-Innovation Center of Efficient Processing and Utilization of Forest Resources,Nanjing Forestry University(Nanjing,210037,China).
文摘In order to enhance the bearing capacity of structural components,save materials,and reduce cost,a glued laminated timber(glulam)I-beam that is theoretically suitable for engineering application was proposed.In this study,18 glulam specimens were fabricated using larch dimension lumber and resorcinol-formaldehyde resin.Four-point bending tests were carried out to compare the ultimate bearing capacity,strain,and deflection of various specimens.The results showed that:(1)The typical failure mode at bending is the web shear failure parallel to grain.Before the failure,cracks and sounds appear at the beam web,which represent the sudden brittle failure.(2)The cross-sectional strain of glulam beam changed linearly with the beam height,indicating that the plane section assumption was basically established.(3)Stiffener could improve the initial flexural stiffness of glulam beam,which experiences an increase of 28.21%.Larger the shear span ratio,smaller the initial flexural stiffness.The initial flexural stiffness improves by 10-23.5%with the increase in the thickness of the lower flange.(4)The effects of stiffener and shear-span ratio on shear strength are relatively significant.After the stiffeners are set at the support and the loading point in pairs,the shear strength of the glulam beam increases by 15.05%averagely.With the increase in the shear-span ratio,the shearing strength of the glulam I-beam gradually reduces.The equation of the shearing strength with the shear span ratio is obtained,which is shown by high fitting precision.(5)The shear strength correlation,as proposed by Soltis and Rammer,is suitable not only for rectangular beams,but also for glulam I-beams.
文摘在认真研究LOCO-I算法的基础上,深入分析了失真控制参数Near对图像压缩比和重建质量的影响,通过对该算法中的Near进行实时动态调整,实现了对图像近无损压缩的压缩比控制,进而可以根据需求来控制图片大小进行压缩。仿真结果表明,提出的压缩比控制方案收敛性较好,输出码流稳定,在满足目标压缩比时重建图像质量较原一阶压缩比控制方案提高了0.5 d B左右。
文摘This paper analyses the changing rule of indoor ozone concentration and its influencing factors.A formula of indoor-outdoor concentration ratio(I/O ratio) was deduced based on the indoor ozone mass-balance equation.The ozone I/O ratio in different kinds of buildings was studied.Results show that I/O ratio is much related to air-exchange rate,which is well compatible with the theoretical calculation results.
