In accordance with previous reports, the sequences related to phosporylated protein segments occur in conserved variable domains of immunoglobulins including first of all certain N-terminally located segments. Consequ...In accordance with previous reports, the sequences related to phosporylated protein segments occur in conserved variable domains of immunoglobulins including first of all certain N-terminally located segments. Consequently, we look here for the sequences 1) composing human and mouse proteins different from antigen receptors, 2) identical with or highly similar to nucleotide sequence representatives of conserved variable immunoglobulin segments and 3) identical with or closely related to phosphorylation sites. More precisely, we searched for the corresponding actual pairs of DNA and protein sequence segments using five-step bilingual approach employing among others a) different types of BLAST searches, b) two in-principle-different machine-learning methods predicting phosphorylated sites and c) two large databases recording existing phosphorylation sites. The approach identified seven existing phosphorylation sites and thirty-seven related human and mouse segments achieving limits for several predictions or phylogenic parameters. Mostly serines phosporylated with ataxia-telangiectasia-related kinase (involved in regulation of DNA-double-strand-break repair) were indicated or predicted in this study. Hypermutation motifs, located in effective positions of the selected sequence segments, occurred significantly less frequently in transcribed than non-transcribed DNA strands suggesting thus the incidence of mutation events. In addition, marked differences between the numbers and proportions of human and mouse cancer-related sequence items were found in different steps of selection process. The possible role of hypermutation changes within the selected segments and the observed structural relationships are discussed here with respect to DNA damage, carcinogenesis, cancer vaccination, ageing and evolution. Taken together, our data represent additional and sometimes perhaps complementary information to the existing databases of empirically proven phosphorylation sites or pathogenically important spots.展开更多
The Denglou Cape, southwest of the Leizhou Peninsula, is the most typical tropical coast in the continent of China.The coastal geomorphic development basics of the geology and Quaternary environment change are discus...The Denglou Cape, southwest of the Leizhou Peninsula, is the most typical tropical coast in the continent of China.The coastal geomorphic development basics of the geology and Quaternary environment change are discussed. Aerial photograph interpretation with fieldwork is applied to draw the outlines of geomorphic types. Based on the investigative data, the exogenic forces and marine organism conditions concerning tropical coast development in the area are expounded, and coastal dynamo-deposition geomorphic bodies are analysed, mainly with sea cliff-abrasion platform,barrier-lagoon system, modern beach, coral reef and mangrove tidal flat, and the general process of coastal evolution at this area, as well as coastline changes since middle Holocene transgression.展开更多
Based on the theories of conventional electrodes, as well as the properties of microdisk electrode, the i-E equations for chronoamperometry at disk microelectrode for reversible, quasi-reversible and irreversible syst...Based on the theories of conventional electrodes, as well as the properties of microdisk electrode, the i-E equations for chronoamperometry at disk microelectrode for reversible, quasi-reversible and irreversible systems are derived. Steady-state voltammograms for the oxidation of [Fe(CN)6]4- , Fe2+ and ascorbic acid were measured at a series of microdisk electrodes with different radii. The conventional log-plot shows that oxidations of [Fe(CN)6]4- and ascorbic acid are reversible and totally irreversible, respectively, but the oxidation of Fe2+ is reversible at larger radius microdisk electrodes and quasi-reversible at smaller radius microdisk electrodes. The application of the log-plot to the voltammograms yielded a straight line, its slope allows us to evaluate the charge transfer coefficient and the intercept gives values of the electron transfer rate constant.展开更多
The typeⅡ codes have been studied widely in applications since their appearance. With analysis of the algebraic structure of finite field of order 4 （i.e., GF（4））, some necessary and sufficient conditions that a ...The typeⅡ codes have been studied widely in applications since their appearance. With analysis of the algebraic structure of finite field of order 4 （i.e., GF（4））, some necessary and sufficient conditions that a generalized H-code （i.e., GH-code） is a type Ⅱ code over GF（4） are given in this article, and an efficient and simple method to generate type Ⅱ codes from GH-codes over GF（4） is shown. The conclusions further extend the coding theory of type Ⅱ.展开更多
We reference the tunneling Hamiltonian to have particle tunneling among different states represented as wave-functions. Our problem applies wave-functionals to a driven sine-Gordon system. We apply the tunneling Hamil...We reference the tunneling Hamiltonian to have particle tunneling among different states represented as wave-functions. Our problem applies wave-functionals to a driven sine-Gordon system. We apply the tunneling Hamiltonian to charge density wave (CDW) transport problems where we consider tunneling among states that are wave-functionals of a scalar quantum field, i.e. derived I-E curves that match Zenier curves used to fit data experimentally with wave-functionals congruent with the false vacuum hypothesis. The open question is whether the coefficients picked in both wave-functionals and the magnitude of the coefficients of the driven sine-Gordon physical system are picked by topological charge arguments that appear to assign values consistent with the false vacuum hypothesis. Crucial results by Fred Cooper et al. allow a mature quantum foam interpretation of false vacuum nucleation for further refinement of our wave-functional results. In doing so, we give credence to topological arguments as a first order phase transition in CDW I-E curves.展开更多
<strong>Introduction:</strong> Modern family planning methods (MFPM) prevent unwanted pregnancies, reduce fertility rate, and increase the interval between pregnancies. They prevent pregnancy by preventing...<strong>Introduction:</strong> Modern family planning methods (MFPM) prevent unwanted pregnancies, reduce fertility rate, and increase the interval between pregnancies. They prevent pregnancy by preventing fertilization or implantation of the fertilized ovum. MFPM include tubal ligation (TL), vasectomy, oral contraceptive pills, the intrauterine contraceptive device (IUCD), depot injections, sub-dermal implants, and male and female condoms. <strong>Objective: </strong>To determine the level of knowledge of modern family planning methods (MFPM) among women of reproductive age (18 - 49 years) at the Mathari North Health Center in Nairobi County, Kenya. <strong>Methods: </strong>The study conducted among women of reproductive age at Mathare North Health Center in Nairobi was a cross-sectional descriptive survey between March 2016 and November 2018. It provided both qualitative and quantitative data. The sample size comprised of 274 women of reproductive age,<em> i.e.</em> (18 - 49 years) attending antenatal and postnatal clinics at the facility. Those excluded were women below 18 years of age, as they could not give consent according to Kenyan Laws. The data were collected using an interviewer-administered structured questionnaire, which consisted of socio-demographic and characteristics, knowledge of modern family planning methods and distance from the facility. Likert scale was used to ensure that data was tabulated on daily basis and subjected to statistical manipulation using Statistical Package for Social Sciences (SPSS). <strong>Results:</strong> The four leading MFPM in use in order of acceptability were injectables, implants, intrauterine contraceptive device and pills in that order. 91% of respondents were aware or had heard about modern family planning methods. Level of education of mother and father were the two variables that influenced the uptake of MFPM with <em>p</em>-values of 0.0260 and 0.025, respectively. The study further found that knowledge of MFPM had a significant influence on their assimilat展开更多
The Beijing Diesel Engine Group Corporation I/E Co. is a subsidiary company under the Beijing Diesel Engine Group Corporation (BDEGC), a foreign window for the enterprise. The BDEGC is the nation’s largest specialize...The Beijing Diesel Engine Group Corporation I/E Co. is a subsidiary company under the Beijing Diesel Engine Group Corporation (BDEGC), a foreign window for the enterprise. The BDEGC is the nation’s largest specialized diesel engine production factory, a super large enterprise at state level. Its main products include six series of motors and the 1040 series light trucks, 6400 and 6401 wagon cars, agricultural self-discharging semitrailers, and light-duty pilothouses and covers. The power of annual diesel engine output has reached 40 million KW, with the products’ coverage rate on the market ranking in a leading position among the same trade nationwide. Since the 1980s, the BDEGC has exported indefinite quantities of展开更多
The Beijing Garment Import and Export Shareholding Corporation, Ltd. was the first shareholding corporation in Beijing which was set up in February 18, 1994. Its predecessor, the Beijing Garment Import and Export Corp...The Beijing Garment Import and Export Shareholding Corporation, Ltd. was the first shareholding corporation in Beijing which was set up in February 18, 1994. Its predecessor, the Beijing Garment Import and Export Corporation, had registered annual import and export earnings of US$300 million, ranking first among the foreign trade corporations in Beijing. Its change into a shareholding corporation has aroused keen interest in garment展开更多
Pigments Everbright Brand pigments, exported in the past four decades, rank first in China for their annual export volume because of wide variety and stable colour. Inorganic pigments: iron oxide red, iron oxide yello...Pigments Everbright Brand pigments, exported in the past four decades, rank first in China for their annual export volume because of wide variety and stable colour. Inorganic pigments: iron oxide red, iron oxide yellow, iron oxide black, ultramaring blue, milori blue, lead oxide red,展开更多
The China National Metals and Minerals I/E Corporation, the core enterprise of the China Metals and Minerals Group, is a special State foreign trade corporation. Since founding in 1950, the corporation has undertaken ...The China National Metals and Minerals I/E Corporation, the core enterprise of the China Metals and Minerals Group, is a special State foreign trade corporation. Since founding in 1950, the corporation has undertaken imports and exports of steel, metals and minerals and building appliances. Under展开更多
文摘In accordance with previous reports, the sequences related to phosporylated protein segments occur in conserved variable domains of immunoglobulins including first of all certain N-terminally located segments. Consequently, we look here for the sequences 1) composing human and mouse proteins different from antigen receptors, 2) identical with or highly similar to nucleotide sequence representatives of conserved variable immunoglobulin segments and 3) identical with or closely related to phosphorylation sites. More precisely, we searched for the corresponding actual pairs of DNA and protein sequence segments using five-step bilingual approach employing among others a) different types of BLAST searches, b) two in-principle-different machine-learning methods predicting phosphorylated sites and c) two large databases recording existing phosphorylation sites. The approach identified seven existing phosphorylation sites and thirty-seven related human and mouse segments achieving limits for several predictions or phylogenic parameters. Mostly serines phosporylated with ataxia-telangiectasia-related kinase (involved in regulation of DNA-double-strand-break repair) were indicated or predicted in this study. Hypermutation motifs, located in effective positions of the selected sequence segments, occurred significantly less frequently in transcribed than non-transcribed DNA strands suggesting thus the incidence of mutation events. In addition, marked differences between the numbers and proportions of human and mouse cancer-related sequence items were found in different steps of selection process. The possible role of hypermutation changes within the selected segments and the observed structural relationships are discussed here with respect to DNA damage, carcinogenesis, cancer vaccination, ageing and evolution. Taken together, our data represent additional and sometimes perhaps complementary information to the existing databases of empirically proven phosphorylation sites or pathogenically important spots.
文摘The Denglou Cape, southwest of the Leizhou Peninsula, is the most typical tropical coast in the continent of China.The coastal geomorphic development basics of the geology and Quaternary environment change are discussed. Aerial photograph interpretation with fieldwork is applied to draw the outlines of geomorphic types. Based on the investigative data, the exogenic forces and marine organism conditions concerning tropical coast development in the area are expounded, and coastal dynamo-deposition geomorphic bodies are analysed, mainly with sea cliff-abrasion platform,barrier-lagoon system, modern beach, coral reef and mangrove tidal flat, and the general process of coastal evolution at this area, as well as coastline changes since middle Holocene transgression.
基金Supported by the National Natural Science Foundation of China Changchun Institute of Applied Chemistry of Chinese Academy of Sciences
文摘Based on the theories of conventional electrodes, as well as the properties of microdisk electrode, the i-E equations for chronoamperometry at disk microelectrode for reversible, quasi-reversible and irreversible systems are derived. Steady-state voltammograms for the oxidation of [Fe(CN)6]4- , Fe2+ and ascorbic acid were measured at a series of microdisk electrodes with different radii. The conventional log-plot shows that oxidations of [Fe(CN)6]4- and ascorbic acid are reversible and totally irreversible, respectively, but the oxidation of Fe2+ is reversible at larger radius microdisk electrodes and quasi-reversible at smaller radius microdisk electrodes. The application of the log-plot to the voltammograms yielded a straight line, its slope allows us to evaluate the charge transfer coefficient and the intercept gives values of the electron transfer rate constant.
基金the National Natural Science Foundation of China (60743007)Fujian Province Young Talent Program (2006F3044)+2 种基金Province Natural Science Foundation of Fujian (JA04169)Province Education Department Foundation of Fujian (JB05331)Beijing Municipal Commission of Education Disciplines and Graduate Education Projects (XK100130648)
文摘The typeⅡ codes have been studied widely in applications since their appearance. With analysis of the algebraic structure of finite field of order 4 （i.e., GF（4））, some necessary and sufficient conditions that a generalized H-code （i.e., GH-code） is a type Ⅱ code over GF（4） are given in this article, and an efficient and simple method to generate type Ⅱ codes from GH-codes over GF（4） is shown. The conclusions further extend the coding theory of type Ⅱ.
文摘We reference the tunneling Hamiltonian to have particle tunneling among different states represented as wave-functions. Our problem applies wave-functionals to a driven sine-Gordon system. We apply the tunneling Hamiltonian to charge density wave (CDW) transport problems where we consider tunneling among states that are wave-functionals of a scalar quantum field, i.e. derived I-E curves that match Zenier curves used to fit data experimentally with wave-functionals congruent with the false vacuum hypothesis. The open question is whether the coefficients picked in both wave-functionals and the magnitude of the coefficients of the driven sine-Gordon physical system are picked by topological charge arguments that appear to assign values consistent with the false vacuum hypothesis. Crucial results by Fred Cooper et al. allow a mature quantum foam interpretation of false vacuum nucleation for further refinement of our wave-functional results. In doing so, we give credence to topological arguments as a first order phase transition in CDW I-E curves.
文摘<strong>Introduction:</strong> Modern family planning methods (MFPM) prevent unwanted pregnancies, reduce fertility rate, and increase the interval between pregnancies. They prevent pregnancy by preventing fertilization or implantation of the fertilized ovum. MFPM include tubal ligation (TL), vasectomy, oral contraceptive pills, the intrauterine contraceptive device (IUCD), depot injections, sub-dermal implants, and male and female condoms. <strong>Objective: </strong>To determine the level of knowledge of modern family planning methods (MFPM) among women of reproductive age (18 - 49 years) at the Mathari North Health Center in Nairobi County, Kenya. <strong>Methods: </strong>The study conducted among women of reproductive age at Mathare North Health Center in Nairobi was a cross-sectional descriptive survey between March 2016 and November 2018. It provided both qualitative and quantitative data. The sample size comprised of 274 women of reproductive age,<em> i.e.</em> (18 - 49 years) attending antenatal and postnatal clinics at the facility. Those excluded were women below 18 years of age, as they could not give consent according to Kenyan Laws. The data were collected using an interviewer-administered structured questionnaire, which consisted of socio-demographic and characteristics, knowledge of modern family planning methods and distance from the facility. Likert scale was used to ensure that data was tabulated on daily basis and subjected to statistical manipulation using Statistical Package for Social Sciences (SPSS). <strong>Results:</strong> The four leading MFPM in use in order of acceptability were injectables, implants, intrauterine contraceptive device and pills in that order. 91% of respondents were aware or had heard about modern family planning methods. Level of education of mother and father were the two variables that influenced the uptake of MFPM with <em>p</em>-values of 0.0260 and 0.025, respectively. The study further found that knowledge of MFPM had a significant influence on their assimilat
文摘The Beijing Diesel Engine Group Corporation I/E Co. is a subsidiary company under the Beijing Diesel Engine Group Corporation (BDEGC), a foreign window for the enterprise. The BDEGC is the nation’s largest specialized diesel engine production factory, a super large enterprise at state level. Its main products include six series of motors and the 1040 series light trucks, 6400 and 6401 wagon cars, agricultural self-discharging semitrailers, and light-duty pilothouses and covers. The power of annual diesel engine output has reached 40 million KW, with the products’ coverage rate on the market ranking in a leading position among the same trade nationwide. Since the 1980s, the BDEGC has exported indefinite quantities of
文摘The Beijing Garment Import and Export Shareholding Corporation, Ltd. was the first shareholding corporation in Beijing which was set up in February 18, 1994. Its predecessor, the Beijing Garment Import and Export Corporation, had registered annual import and export earnings of US$300 million, ranking first among the foreign trade corporations in Beijing. Its change into a shareholding corporation has aroused keen interest in garment
文摘Pigments Everbright Brand pigments, exported in the past four decades, rank first in China for their annual export volume because of wide variety and stable colour. Inorganic pigments: iron oxide red, iron oxide yellow, iron oxide black, ultramaring blue, milori blue, lead oxide red,
文摘The China National Metals and Minerals I/E Corporation, the core enterprise of the China Metals and Minerals Group, is a special State foreign trade corporation. Since founding in 1950, the corporation has undertaken imports and exports of steel, metals and minerals and building appliances. Under
