目的分析我国老年人高血压的患病率,以及知晓、治疗和控制状况。方法使用2012-2015年全国高血压分层多阶段随机抽样横断面调查资料[国家"十二五"科技支撑计划项目"中国重要心血管病调查及关键技术研究"]进行分析,...目的分析我国老年人高血压的患病率,以及知晓、治疗和控制状况。方法使用2012-2015年全国高血压分层多阶段随机抽样横断面调查资料[国家"十二五"科技支撑计划项目"中国重要心血管病调查及关键技术研究"]进行分析,其中老年人(年龄≥60岁)134 397人。老年人高血压定义为平均收缩压≥140和(或)舒张压≥90 mm Hg或近2周内服用降压药物;单纯收缩期高血压定义为收缩压≥140和舒张压<90 mm Hg,单纯舒张期高血压定义为收缩压<140和舒张压≥90 mm Hg,血压控制定义为收缩压<140和舒张压<90 mm Hg。结果我国老年人高血压患病率为53.24%(约9450万人),单纯收缩期高血压患病率为30.33%(约5380万人),单纯舒张期高血压患病率为1.32%(约234万人),单纯收缩期高血压占老年高血压总人数的56.95%。城市和农村居民的老年高血压患病率比较,差异无统计学意义(53.38%比53.20%,P=0.904),但女性高于男性(55.28%比51.14%,P<0.001)。在老年高血压患者中,知晓率57.08%,治疗率51.35%,控制率仅18.20%。结论老年人高血压知晓、治疗和控制率有所提高,但整体仍低。展开更多
Background Hypertensive target organ damage （TOD） is the main reason for mortality or disability in elderly hypertensive patients. The studies on TOD of hypertension in Asia, especially in Chinese elderly hypertensi...Background Hypertensive target organ damage （TOD） is the main reason for mortality or disability in elderly hypertensive patients. The studies on TOD of hypertension in Asia, especially in Chinese elderly hypertensive patients, are very limited. The aim of this study was to evaluate the prevalence and correlative factors of TOD in older Chinese hypertensive inpatients. Methods This is a retrospective survey and data were collected from the computerized medical files of hypertensive inpatients from January of 1993 to December of 2008. The analysis was done on 17 682 inpatients, aged 60 years or older, with a diagnosis of essential hypertension （EH）. The evidence of hypertensive TOD and associated factors with TOD were collected. Results The prevalence of any hypertensive target organ involvement among these subjects was high. In multivariable Logistic regressions adjusted for potentially confounding factors, older age, male gender, diabetes, EH grade 3, systolic blood pressure （SBP）, and low-density lipoprotein cholesterol （LDL-C）, were independently associated with coronary artery disease. Age, duration of EH, EH grade 3, SBP, pulse pressure （PP）, and homocysteine （Hcy） were independently associated with cerebrovascular disease. Age, diabetes, duration of EH, EH grade 3, SBP, PP and estimated glomerular filtration rate （eGFR） were independently associated with chronic kidney disease. Male gender, EH grade 3 and SBP were independently associated with aortic dissection. Conclusions The prevalence of hypertensive TOD is high in older Chinese hypertensive inpatients. Various cardiovascular risk factors are associated with hypertensive TOD. The level of SBP and severe hypertension （grade 3 hypertension） are common independent risk factors of TOD.展开更多
目的研究对比乌拉地尔与硝酸甘油在老年高血压合并糖尿病患者发生急性心力衰竭时的疗效。方法将82名老年高血压合并糖尿病并发急性心力衰竭患者,采用数字表法将患者分为硝酸甘油组及乌拉地尔治疗组。观察不同时段2组患者血压、心率的变...目的研究对比乌拉地尔与硝酸甘油在老年高血压合并糖尿病患者发生急性心力衰竭时的疗效。方法将82名老年高血压合并糖尿病并发急性心力衰竭患者,采用数字表法将患者分为硝酸甘油组及乌拉地尔治疗组。观察不同时段2组患者血压、心率的变化情况,反映心功能指标的N末端B型利钠肽原(N terminal B type natriuretic peptide,NT-pro BNP)、射血分数等指标变化情况,观察血糖、血脂浓度及肝、肾功能的情况。结果乌拉地尔组对收缩压的控制及NT-pro BNP的改善明显优于硝酸甘油组。乌拉地尔组在治疗第7天,射血分数较硝酸甘油组明显升高,左室舒张末期容积减小。对心率及糖脂代谢无不良影响。治疗过程中乌拉地尔无不良事件发生。结论乌拉地尔在平稳降压,通过减轻心脏后负荷,从而改善心功能。对糖耐量、血脂代谢无不良影响。药效安全、可靠,未出现耐药反应。展开更多
文摘目的分析我国老年人高血压的患病率,以及知晓、治疗和控制状况。方法使用2012-2015年全国高血压分层多阶段随机抽样横断面调查资料[国家"十二五"科技支撑计划项目"中国重要心血管病调查及关键技术研究"]进行分析,其中老年人(年龄≥60岁)134 397人。老年人高血压定义为平均收缩压≥140和(或)舒张压≥90 mm Hg或近2周内服用降压药物;单纯收缩期高血压定义为收缩压≥140和舒张压<90 mm Hg,单纯舒张期高血压定义为收缩压<140和舒张压≥90 mm Hg,血压控制定义为收缩压<140和舒张压<90 mm Hg。结果我国老年人高血压患病率为53.24%(约9450万人),单纯收缩期高血压患病率为30.33%(约5380万人),单纯舒张期高血压患病率为1.32%(约234万人),单纯收缩期高血压占老年高血压总人数的56.95%。城市和农村居民的老年高血压患病率比较,差异无统计学意义(53.38%比53.20%,P=0.904),但女性高于男性(55.28%比51.14%,P<0.001)。在老年高血压患者中,知晓率57.08%,治疗率51.35%,控制率仅18.20%。结论老年人高血压知晓、治疗和控制率有所提高,但整体仍低。
文摘Background Hypertensive target organ damage （TOD） is the main reason for mortality or disability in elderly hypertensive patients. The studies on TOD of hypertension in Asia, especially in Chinese elderly hypertensive patients, are very limited. The aim of this study was to evaluate the prevalence and correlative factors of TOD in older Chinese hypertensive inpatients. Methods This is a retrospective survey and data were collected from the computerized medical files of hypertensive inpatients from January of 1993 to December of 2008. The analysis was done on 17 682 inpatients, aged 60 years or older, with a diagnosis of essential hypertension （EH）. The evidence of hypertensive TOD and associated factors with TOD were collected. Results The prevalence of any hypertensive target organ involvement among these subjects was high. In multivariable Logistic regressions adjusted for potentially confounding factors, older age, male gender, diabetes, EH grade 3, systolic blood pressure （SBP）, and low-density lipoprotein cholesterol （LDL-C）, were independently associated with coronary artery disease. Age, duration of EH, EH grade 3, SBP, pulse pressure （PP）, and homocysteine （Hcy） were independently associated with cerebrovascular disease. Age, diabetes, duration of EH, EH grade 3, SBP, PP and estimated glomerular filtration rate （eGFR） were independently associated with chronic kidney disease. Male gender, EH grade 3 and SBP were independently associated with aortic dissection. Conclusions The prevalence of hypertensive TOD is high in older Chinese hypertensive inpatients. Various cardiovascular risk factors are associated with hypertensive TOD. The level of SBP and severe hypertension （grade 3 hypertension） are common independent risk factors of TOD.
文摘目的研究对比乌拉地尔与硝酸甘油在老年高血压合并糖尿病患者发生急性心力衰竭时的疗效。方法将82名老年高血压合并糖尿病并发急性心力衰竭患者,采用数字表法将患者分为硝酸甘油组及乌拉地尔治疗组。观察不同时段2组患者血压、心率的变化情况,反映心功能指标的N末端B型利钠肽原(N terminal B type natriuretic peptide,NT-pro BNP)、射血分数等指标变化情况,观察血糖、血脂浓度及肝、肾功能的情况。结果乌拉地尔组对收缩压的控制及NT-pro BNP的改善明显优于硝酸甘油组。乌拉地尔组在治疗第7天,射血分数较硝酸甘油组明显升高,左室舒张末期容积减小。对心率及糖脂代谢无不良影响。治疗过程中乌拉地尔无不良事件发生。结论乌拉地尔在平稳降压,通过减轻心脏后负荷,从而改善心功能。对糖耐量、血脂代谢无不良影响。药效安全、可靠,未出现耐药反应。
