Background: The radical hysterectomy (RH) surgical technique has improved along the years. It is used for the treatment of cervical cancer, endometrial cancer when affecting the cervix, and upper vaginal carcinomas...Background: The radical hysterectomy (RH) surgical technique has improved along the years. It is used for the treatment of cervical cancer, endometrial cancer when affecting the cervix, and upper vaginal carcinomas. Our aim was to describe the historical evolution of the technique after the introduction of laparoseopy at our institution. Methods: We performed a retrospective review of medical records of patients who underwent RH, grouped in three periods according to the year of surgery: 1990-1999, 2000-2009 and 2010-2013. Patients' characteristics, pathologic details, intraoperative and postoperative complications were analyzed and comoared throughout the time periods. Results: A total of 102 cases of RH were performed at our center during the study period. Among all data collected, the presence of necrosis, age, number of lymph nodes, surgery route, operating time, hospital stay, blood loss and transfusion requirement were statistically significant different among groups. Conversion to laparotomy rate was 19% for the second period compared to the absence of cases in the last one. No significant differences (P=0.124) were observed in the adjuvant treatment received among the three different groups. At the time of the last contact the patients free of disease were 12 (85.7%), 53 (91.3%) and 26 (86.6%) respectively (P=0.406). Regarding the disease-free interval, we found significant better outcomes in the group of laparotomy compared to laparoscopy (P=0.015).Conclusions: Laparoscopic RH is an acceptable surgery with advantages like magnified vision of the operation's field, lower surgical complications, shorter hospital stay and earlier resumption to daily activities.展开更多
Background: Cancer patients frequently suffer from mental health problems because of their reactions to their cancer diagnosis, cancer type, treatment effects, recurrence, fear of the end-of-life, survival, and financ...Background: Cancer patients frequently suffer from mental health problems because of their reactions to their cancer diagnosis, cancer type, treatment effects, recurrence, fear of the end-of-life, survival, and financial burden. Some hospitals have integrated mental health assessments into cancer care, but our centre has little experience with this practice. Aim and Objectives: To ascertain the prevalence and predictors of anxiety and depression in patients with gynaecological cancer at a tertiary health facility in southern Nigeria. Materials and Methods: This was a facility-based cross-sectional descriptive study of 75 women with histologically confirmed gynaecological cancer managed at the University of Port Harcourt Teaching Hospital, Port Harcourt, from January 1, 2022, to December 31, 2022. Individuals having a history of drug addiction, severe cognitive impairment, non-consenting patients, and those with communication difficulties were excluded from the study. A data collection form was used to obtain socio-demographic, reproductive, and clinical characteristics, while the Hospital Anxiety and Depression Scale (HADS) was used to assess for anxiety and depression. Data was analyzed using descriptive statistics to determine the association of variables with anxiety and depression. Results: Most 27 (36.0%) of the respondents were in 40 - 49 age group with a mean age of 50.4 ± 12.3 years. The study showed that 39 (52.0%) of the respondents exhibited symptoms of anxiety, of which 14 (35.9%) were mild, 20 (51.3%) had moderate anxiety and 5 (12.8%) experienced severe anxiety. In addition, 46 (61.3%) of them showed symptoms of depression, of which 17 (37.0%) were mild, 15 (32.6%) were moderate and 14 (30.4%) experienced severe depression. The ratio of respondents who showed anxiety to those that showed symptoms of depression was 5: 6. The factors associated with anxiety were partner’s educational level (X<sup>2</sup> = 4.745, p = 0.029), parity (X<sup>2</sup> = 6.651, p = 0.036) and duration of diagnosis (X<sup展开更多
This report documents a rare case of complete spontaneous regression of clear cell carcinoma of the endometrium. An elderly woman with paranoid schizophrenia was admitted to the hospital because of vaginal bleeding. D...This report documents a rare case of complete spontaneous regression of clear cell carcinoma of the endometrium. An elderly woman with paranoid schizophrenia was admitted to the hospital because of vaginal bleeding. Diagnostic curetting and biopsy were performed and she was diagnosed with clear cell carcinoma of endometrium. Anti-tumour therapy was not possible because of her poor psychiatric status. 13 months later the woman died of a natural cause and at autopsy the endometrial tumour could no longer be identified. Myocardial infarction, aggravated by poor functional status of organism due to sepsis, was concluded to be the cause of death.展开更多
Nowadays, cancer is one of the main worldwide causes of death and an increasing issue in public health. In the European Union, it is the first work-related cause of death. Studies about occupational risk exposure are ...Nowadays, cancer is one of the main worldwide causes of death and an increasing issue in public health. In the European Union, it is the first work-related cause of death. Studies about occupational risk exposure are a useful field of investigation to determine cancerous elements;special attention is paid to the relationship between cancer and work in women, who must constantly adapt to the working market and the new working fields, with their diverse degrees of exposure to risks. This revision has reviewed the bibliography gathered in Medline related to breast cancer, cervix cancer, uterus cancer, and ovarian cancer, along with their relationship with different work-related risks and types of working roles. The results have shown enough scientific evidence to suspect that work related exposition could be a plausible cause of these gynaecological cancers. Therefore, we want to stress the need of enhancing the coordinated investigation between all the medical specialties involved, and to encourage the spread of the necessary knowledge to manage and prevent them.展开更多
因妊娠期肿瘤罕见并缺乏共识促成了国际癌症、不孕与妊娠网络(the International Network on Cancer,Infertility and Pregnancy,INCIP)的建立,该协会旨在促进妊娠期肿瘤的管理并利于大规模研究。本次共识旨在发布新的循证医学信息和专...因妊娠期肿瘤罕见并缺乏共识促成了国际癌症、不孕与妊娠网络(the International Network on Cancer,Infertility and Pregnancy,INCIP)的建立,该协会旨在促进妊娠期肿瘤的管理并利于大规模研究。本次共识旨在发布新的循证医学信息和专家见解,以修订和加强在2009年和2014年发布的指南,促进对妊娠期妇科肿瘤患者及其子代的有效管理。展开更多
目的通过运用三层次需求调查问卷(the three levels of needs questionnaire,3LNQ)评估妇科恶性肿瘤终末期患者肿瘤相关症状存在的情况以及相应的需求,为护理临床实施有效的终末期姑息治疗方案提供客观依据,从而提升妇科恶性肿瘤终末期...目的通过运用三层次需求调查问卷(the three levels of needs questionnaire,3LNQ)评估妇科恶性肿瘤终末期患者肿瘤相关症状存在的情况以及相应的需求,为护理临床实施有效的终末期姑息治疗方案提供客观依据,从而提升妇科恶性肿瘤终末期患者的生存质量。方法运用基本信息采集表、健康状况简表(SF-36)、3LNQ陆续对70例妇科恶性肿瘤3期及4期患者进行横断面调查研究,同时了解其肿瘤相关症状存在的情况以及相应的需求。结果受访患者的平均年龄(61±9.26)岁,其中65.7%被诊断为卵巢癌。在这些患者中,87.1%感觉自己是家庭的负担。最普遍存在的症状是疲劳,且很大程度上并未得到足够的重视和及时的干预。结论终末期妇科恶性肿瘤患者普遍感觉疲劳且大多存在一定程度上的精神困扰,在问卷调查结果基础上有针对性的姑息治疗方案有益于提高终末期妇科恶性肿瘤患者的生存质量。展开更多
文摘Background: The radical hysterectomy (RH) surgical technique has improved along the years. It is used for the treatment of cervical cancer, endometrial cancer when affecting the cervix, and upper vaginal carcinomas. Our aim was to describe the historical evolution of the technique after the introduction of laparoseopy at our institution. Methods: We performed a retrospective review of medical records of patients who underwent RH, grouped in three periods according to the year of surgery: 1990-1999, 2000-2009 and 2010-2013. Patients' characteristics, pathologic details, intraoperative and postoperative complications were analyzed and comoared throughout the time periods. Results: A total of 102 cases of RH were performed at our center during the study period. Among all data collected, the presence of necrosis, age, number of lymph nodes, surgery route, operating time, hospital stay, blood loss and transfusion requirement were statistically significant different among groups. Conversion to laparotomy rate was 19% for the second period compared to the absence of cases in the last one. No significant differences (P=0.124) were observed in the adjuvant treatment received among the three different groups. At the time of the last contact the patients free of disease were 12 (85.7%), 53 (91.3%) and 26 (86.6%) respectively (P=0.406). Regarding the disease-free interval, we found significant better outcomes in the group of laparotomy compared to laparoscopy (P=0.015).Conclusions: Laparoscopic RH is an acceptable surgery with advantages like magnified vision of the operation's field, lower surgical complications, shorter hospital stay and earlier resumption to daily activities.
文摘Background: Cancer patients frequently suffer from mental health problems because of their reactions to their cancer diagnosis, cancer type, treatment effects, recurrence, fear of the end-of-life, survival, and financial burden. Some hospitals have integrated mental health assessments into cancer care, but our centre has little experience with this practice. Aim and Objectives: To ascertain the prevalence and predictors of anxiety and depression in patients with gynaecological cancer at a tertiary health facility in southern Nigeria. Materials and Methods: This was a facility-based cross-sectional descriptive study of 75 women with histologically confirmed gynaecological cancer managed at the University of Port Harcourt Teaching Hospital, Port Harcourt, from January 1, 2022, to December 31, 2022. Individuals having a history of drug addiction, severe cognitive impairment, non-consenting patients, and those with communication difficulties were excluded from the study. A data collection form was used to obtain socio-demographic, reproductive, and clinical characteristics, while the Hospital Anxiety and Depression Scale (HADS) was used to assess for anxiety and depression. Data was analyzed using descriptive statistics to determine the association of variables with anxiety and depression. Results: Most 27 (36.0%) of the respondents were in 40 - 49 age group with a mean age of 50.4 ± 12.3 years. The study showed that 39 (52.0%) of the respondents exhibited symptoms of anxiety, of which 14 (35.9%) were mild, 20 (51.3%) had moderate anxiety and 5 (12.8%) experienced severe anxiety. In addition, 46 (61.3%) of them showed symptoms of depression, of which 17 (37.0%) were mild, 15 (32.6%) were moderate and 14 (30.4%) experienced severe depression. The ratio of respondents who showed anxiety to those that showed symptoms of depression was 5: 6. The factors associated with anxiety were partner’s educational level (X<sup>2</sup> = 4.745, p = 0.029), parity (X<sup>2</sup> = 6.651, p = 0.036) and duration of diagnosis (X<sup
文摘This report documents a rare case of complete spontaneous regression of clear cell carcinoma of the endometrium. An elderly woman with paranoid schizophrenia was admitted to the hospital because of vaginal bleeding. Diagnostic curetting and biopsy were performed and she was diagnosed with clear cell carcinoma of endometrium. Anti-tumour therapy was not possible because of her poor psychiatric status. 13 months later the woman died of a natural cause and at autopsy the endometrial tumour could no longer be identified. Myocardial infarction, aggravated by poor functional status of organism due to sepsis, was concluded to be the cause of death.
文摘Nowadays, cancer is one of the main worldwide causes of death and an increasing issue in public health. In the European Union, it is the first work-related cause of death. Studies about occupational risk exposure are a useful field of investigation to determine cancerous elements;special attention is paid to the relationship between cancer and work in women, who must constantly adapt to the working market and the new working fields, with their diverse degrees of exposure to risks. This revision has reviewed the bibliography gathered in Medline related to breast cancer, cervix cancer, uterus cancer, and ovarian cancer, along with their relationship with different work-related risks and types of working roles. The results have shown enough scientific evidence to suspect that work related exposition could be a plausible cause of these gynaecological cancers. Therefore, we want to stress the need of enhancing the coordinated investigation between all the medical specialties involved, and to encourage the spread of the necessary knowledge to manage and prevent them.
文摘因妊娠期肿瘤罕见并缺乏共识促成了国际癌症、不孕与妊娠网络(the International Network on Cancer,Infertility and Pregnancy,INCIP)的建立,该协会旨在促进妊娠期肿瘤的管理并利于大规模研究。本次共识旨在发布新的循证医学信息和专家见解,以修订和加强在2009年和2014年发布的指南,促进对妊娠期妇科肿瘤患者及其子代的有效管理。
文摘目的通过运用三层次需求调查问卷(the three levels of needs questionnaire,3LNQ)评估妇科恶性肿瘤终末期患者肿瘤相关症状存在的情况以及相应的需求,为护理临床实施有效的终末期姑息治疗方案提供客观依据,从而提升妇科恶性肿瘤终末期患者的生存质量。方法运用基本信息采集表、健康状况简表(SF-36)、3LNQ陆续对70例妇科恶性肿瘤3期及4期患者进行横断面调查研究,同时了解其肿瘤相关症状存在的情况以及相应的需求。结果受访患者的平均年龄(61±9.26)岁,其中65.7%被诊断为卵巢癌。在这些患者中,87.1%感觉自己是家庭的负担。最普遍存在的症状是疲劳,且很大程度上并未得到足够的重视和及时的干预。结论终末期妇科恶性肿瘤患者普遍感觉疲劳且大多存在一定程度上的精神困扰,在问卷调查结果基础上有针对性的姑息治疗方案有益于提高终末期妇科恶性肿瘤患者的生存质量。