目的全面了解我国门静脉高压食管胃静脉曲张内镜治疗的现状,为我国内镜治疗的发展提供数据支持和参考。方法本研究由中国肝脏健康联盟(Liver Health Consortium in China,CHESS)发起,通过网络分发调查问卷了解2022年国内开展门静脉高压...目的全面了解我国门静脉高压食管胃静脉曲张内镜治疗的现状,为我国内镜治疗的发展提供数据支持和参考。方法本研究由中国肝脏健康联盟(Liver Health Consortium in China,CHESS)发起,通过网络分发调查问卷了解2022年国内开展门静脉高压食管胃静脉曲张内镜治疗的基本情况。问卷问题主要包括各类内镜治疗例数和适应证,依照指南预防食管胃静脉曲张出血(esophagogastric variceal bleeding,EGVB)的依从性,急性EGVB的处理、治疗时机,胃底及特殊类型静脉曲张的处理、内镜治疗的改善等方面。统计各项治疗数据的医院数量占参与调查问卷医院数量的比例,各级医院的指南依从性比较使用卡方检验进行分析。结果31个省(自治区、直辖市)共836家医院参与本调研,调查显示内镜治疗的主要适应证是控制急性出血(49.3%,412/836)和预防再出血(38.3%,320/836)。参与调研医院对于我国指南中EGVB一级预防的推荐意见(非选择性β受体阻滞剂或内镜治疗)的依从性为72.5%(606/836),对于EGVB二级预防推荐意见(非选择性β受体阻滞剂联合内镜治疗)的依从性为39.2%(328/836),三级医院和二级医院对于一级预防[71.0%(495/697)比79.9%(111/139),χ^(2)=4.11,P=0.033]和二级预防的依从性[41.6%(290/697)比27.3%(38/139),χ^(2)=9.31,P=0.002]差异有统计学意义。78.2%(654/836)的医院首选内镜治疗处理急性EGVB,三级医院首选内镜治疗的比例明显高于二级医院[82.6%(576/697)比56.1%(78/139),χ^(2)=46.33,P<0.001]。治疗时机通常为出血后12h内(48.5%,317/654)和12~24h(36.9%,241/654)。对于近贲门大弯侧的胃底静脉曲张和孤立性胃静脉曲张,分别有48.2%(403/836)和29.9%(250/836)的医院首选组织胶联合硬化剂注射进行处理,而12.4%(104/836)和26.4%(221/836)的医院首选以止血夹为基础的内镜治疗术式。参与调研医院认为提高内镜医师水平(84.2%,704/836)和对患者进行准确的术前评估并提展开更多
Purpose.This study aimed to examine the levels and correlates of 24-h movement behaviors(i.e.,physical activity,sedentary time,and sleep),and different patterns of these behaviors in a nationally representative sample...Purpose.This study aimed to examine the levels and correlates of 24-h movement behaviors(i.e.,physical activity,sedentary time,and sleep),and different patterns of these behaviors in a nationally representative sample of South Koreans aged 12 years and older.This study also aimed to examine the sociodemographic correlates of 24?h movement behaviors stratified by age groups.Methods.Self-reported,repeated cross-sectional data from 10,708 participants in the 2014 and 2015 Korea National Health and Nutrition Examination surveys were used.Key variables included moderate-to-vigorous intensity physical activity,muscular strengthening exercises,walking,active transportation,sedentary time,and sleep.Sociodemographic variables included age,sex,household income,area of residence,and education level.Descriptive statistics by sex and age as well as general linear models by age group were performed.Results.The proportions of individuals meeting the moderate-to-vigorous intensity physical activity,muscular strengthening exercises,and sleep guidelines were,respectively,21.6%,22.1%,and 32.5%in male youth;6.9%,4.5%,and 22.8%in female youth;55.5%,30.8%,and 54.0%in male adults;48.8%,14.4%,and 57.6%in female adults;44.0%,30.6%,and 45.5%in male older adults;and 29.5%,8.9%,and 37.3%in female older adults.The proportions of individuals showing the most ideal combinations of 24-h movement behaviors were only 3.2%in youth,0.4%in adults,and 0 in older adults.Universally,older age,female sex,or living in metro Seoul were associated with unfavorable patterns of 24-h movement behaviors across different age groups.However,the associations of income and education with movement behaviors were mixed across age groups.Conclusion.Overall,the proportion of South Koreans with a healthy 24-h movement behavior pattern is low.The sociodemographic correlates of different types of 24-h movement behaviors should be considered when designing targeted interventions for the promotion of healthy active living for South Koreans.展开更多
Irreproducibility of research causes a major concern in academia.This concern affects all study designs regardless of scientific fields.Without testing the reproducibility and replicability it is almost impossible to ...Irreproducibility of research causes a major concern in academia.This concern affects all study designs regardless of scientific fields.Without testing the reproducibility and replicability it is almost impossible to repeat the research and to gain the same or similar results.In addition,irreproducibility limits the translation of research findings into practice where the same results are expected.To find the solutions,the Interacademy Partnership for Health gathered academics from established networks of science,medicine and engineering around a table to introduce seven strategies that can enhance the reproducibility:pre-registration,open methods,open data,collaboration,automation,reporting guidelines,and post-publication reviews.The current editorial discusses the generalisability and practicality of these strategies to systematic reviews and claims that systematic reviews have even a greater potential than other research designs to lead the movement toward the reproducibility of research.Moreover,I discuss the potential of reproducibility,on the other hand,to upgrade the systematic review from review to research.Furthermore,there are references to the successful and ongoing practices from collaborative efforts around the world to encourage the systematic reviewers,the journal editors and publishers,the organizations linked to evidence synthesis,and the funders and policy makers to facilitate this movement and to gain the public trust in research.展开更多
文摘目的全面了解我国门静脉高压食管胃静脉曲张内镜治疗的现状,为我国内镜治疗的发展提供数据支持和参考。方法本研究由中国肝脏健康联盟(Liver Health Consortium in China,CHESS)发起,通过网络分发调查问卷了解2022年国内开展门静脉高压食管胃静脉曲张内镜治疗的基本情况。问卷问题主要包括各类内镜治疗例数和适应证,依照指南预防食管胃静脉曲张出血(esophagogastric variceal bleeding,EGVB)的依从性,急性EGVB的处理、治疗时机,胃底及特殊类型静脉曲张的处理、内镜治疗的改善等方面。统计各项治疗数据的医院数量占参与调查问卷医院数量的比例,各级医院的指南依从性比较使用卡方检验进行分析。结果31个省(自治区、直辖市)共836家医院参与本调研,调查显示内镜治疗的主要适应证是控制急性出血(49.3%,412/836)和预防再出血(38.3%,320/836)。参与调研医院对于我国指南中EGVB一级预防的推荐意见(非选择性β受体阻滞剂或内镜治疗)的依从性为72.5%(606/836),对于EGVB二级预防推荐意见(非选择性β受体阻滞剂联合内镜治疗)的依从性为39.2%(328/836),三级医院和二级医院对于一级预防[71.0%(495/697)比79.9%(111/139),χ^(2)=4.11,P=0.033]和二级预防的依从性[41.6%(290/697)比27.3%(38/139),χ^(2)=9.31,P=0.002]差异有统计学意义。78.2%(654/836)的医院首选内镜治疗处理急性EGVB,三级医院首选内镜治疗的比例明显高于二级医院[82.6%(576/697)比56.1%(78/139),χ^(2)=46.33,P<0.001]。治疗时机通常为出血后12h内(48.5%,317/654)和12~24h(36.9%,241/654)。对于近贲门大弯侧的胃底静脉曲张和孤立性胃静脉曲张,分别有48.2%(403/836)和29.9%(250/836)的医院首选组织胶联合硬化剂注射进行处理,而12.4%(104/836)和26.4%(221/836)的医院首选以止血夹为基础的内镜治疗术式。参与调研医院认为提高内镜医师水平(84.2%,704/836)和对患者进行准确的术前评估并提
文摘Purpose.This study aimed to examine the levels and correlates of 24-h movement behaviors(i.e.,physical activity,sedentary time,and sleep),and different patterns of these behaviors in a nationally representative sample of South Koreans aged 12 years and older.This study also aimed to examine the sociodemographic correlates of 24?h movement behaviors stratified by age groups.Methods.Self-reported,repeated cross-sectional data from 10,708 participants in the 2014 and 2015 Korea National Health and Nutrition Examination surveys were used.Key variables included moderate-to-vigorous intensity physical activity,muscular strengthening exercises,walking,active transportation,sedentary time,and sleep.Sociodemographic variables included age,sex,household income,area of residence,and education level.Descriptive statistics by sex and age as well as general linear models by age group were performed.Results.The proportions of individuals meeting the moderate-to-vigorous intensity physical activity,muscular strengthening exercises,and sleep guidelines were,respectively,21.6%,22.1%,and 32.5%in male youth;6.9%,4.5%,and 22.8%in female youth;55.5%,30.8%,and 54.0%in male adults;48.8%,14.4%,and 57.6%in female adults;44.0%,30.6%,and 45.5%in male older adults;and 29.5%,8.9%,and 37.3%in female older adults.The proportions of individuals showing the most ideal combinations of 24-h movement behaviors were only 3.2%in youth,0.4%in adults,and 0 in older adults.Universally,older age,female sex,or living in metro Seoul were associated with unfavorable patterns of 24-h movement behaviors across different age groups.However,the associations of income and education with movement behaviors were mixed across age groups.Conclusion.Overall,the proportion of South Koreans with a healthy 24-h movement behavior pattern is low.The sociodemographic correlates of different types of 24-h movement behaviors should be considered when designing targeted interventions for the promotion of healthy active living for South Koreans.
文摘Irreproducibility of research causes a major concern in academia.This concern affects all study designs regardless of scientific fields.Without testing the reproducibility and replicability it is almost impossible to repeat the research and to gain the same or similar results.In addition,irreproducibility limits the translation of research findings into practice where the same results are expected.To find the solutions,the Interacademy Partnership for Health gathered academics from established networks of science,medicine and engineering around a table to introduce seven strategies that can enhance the reproducibility:pre-registration,open methods,open data,collaboration,automation,reporting guidelines,and post-publication reviews.The current editorial discusses the generalisability and practicality of these strategies to systematic reviews and claims that systematic reviews have even a greater potential than other research designs to lead the movement toward the reproducibility of research.Moreover,I discuss the potential of reproducibility,on the other hand,to upgrade the systematic review from review to research.Furthermore,there are references to the successful and ongoing practices from collaborative efforts around the world to encourage the systematic reviewers,the journal editors and publishers,the organizations linked to evidence synthesis,and the funders and policy makers to facilitate this movement and to gain the public trust in research.
