Gingival enlargement is one of the frequent features of gingival diseases. However due to their varied presentations, the diagnosis of these entities becomes challenging for the clinician. They can be categorized base...Gingival enlargement is one of the frequent features of gingival diseases. However due to their varied presentations, the diagnosis of these entities becomes challenging for the clinician. They can be categorized based on their etiopathogenesis, location, size, extent, etc. Based on the existing knowledge and clinical experience, a differential diagnosis can be formulated. Subsequently, after detailed investigation, clinician makes a final diagnosis or diagnosis of exclusion. A perfect diagnosis is critically important, since the management of these lesions and prevention of their recurrence is completely dependent on it. Furthermore, in some cases where gingival enlargement could be the primary sign of potentially lethal systemic diseases, a correct diagnosis of these enlargements could prove life saving for the patient or at least initiate early treatment and improve the quality of life. The purpose of this review article is to highlight significant findings of different types of gingival enlargement which would help clinician to differentiate between them. A detailed decision tree is also designed for the practitioners, which will help them arrive at a diagnosis in a systematic manner. There still could be some lesions which may present in an unusual manner and make the diagnosis challenging. By knowing the existence of common and rare presentations of gingival enlargement, one can keep a broad view when formulating a differential diagnosis of localized(isolated, discrete, regional) or generalized gingival enlargement.展开更多
The fibrous epulis, a common tumor-like lesion of the gingiva, appears in the interdental papilla as a result of local irritation. Lesions are asymptomatic and have a variable growth rate. A 75-year-old woman was refe...The fibrous epulis, a common tumor-like lesion of the gingiva, appears in the interdental papilla as a result of local irritation. Lesions are asymptomatic and have a variable growth rate. A 75-year-old woman was referred for the evaluation of a large painless gingival mass. It had started 10 years back and has been increasing in size the last year. No bone involvement was noted. The tumor was totally removed by excision with surgical scalpel under local anesthesia without teeth extraction. The microscopic findings were suggestive of a fibrous epulis. Differential diagnosis, clinical considerations and factors to prevent recurrence are discussed.展开更多
We present the case of a 45-year-old Hispanic female with a slowly enlarging mass on her left maxilla in the region of teeth #15 and #16. A differential diagnosis is presented along with the histologic findings and tr...We present the case of a 45-year-old Hispanic female with a slowly enlarging mass on her left maxilla in the region of teeth #15 and #16. A differential diagnosis is presented along with the histologic findings and treatment rendered. The prognosis and biology of the lesion are discussed.展开更多
目的检测富血小板纤维蛋白(PRF)膜与胶原膜修复拔牙术后牙龈缺损各时间节点的分泌物中钙结合蛋白和胶原酶-1的水平,评价PRF对牙龈缺损的修复和调节局部炎性反应的能力。方法选取2013年8月至2014年12月到成都军区机关医院种植修复临床专...目的检测富血小板纤维蛋白(PRF)膜与胶原膜修复拔牙术后牙龈缺损各时间节点的分泌物中钙结合蛋白和胶原酶-1的水平,评价PRF对牙龈缺损的修复和调节局部炎性反应的能力。方法选取2013年8月至2014年12月到成都军区机关医院种植修复临床专科中心就诊,需拔除磨牙并同期进行位点保存的患牙16例,随机分为PRF膜组和胶原膜组,各8例。拔牙后,牙槽窝内植入Bio-Oss骨替代材料,表面分别覆盖PRF膜或胶原膜。通过ELISA检测术区在术后3、7、14、21、28 d创面分泌物中胶原酶-1和钙结合蛋白的水平,动态评价PRF对牙龈缺损的修复和调节局部炎性反应的能力。结果钙结合蛋白水平在术后3、7 d胶原膜组均明显高于PRF膜组,差异均有统计学意义(P<0.05);术后14、21、28 d胶原膜组稍高于PRF膜组,但差异无统计学意义(P>0.05)。胶原酶-1水平在术后3、7 d PRF膜组均明显高于胶原膜组,差异均有统计学意义(P<0.05);术后14、21、28 d PRF组稍高于胶原膜组,差异均无统计学意义(P>0.05)。结论PRF能促进牙龈缺损的修复,减轻术区局部炎性反应。PRF膜是一种有一定抗感染能力的生物活性再生平台材料,有一定的临床价值。展开更多
文摘Gingival enlargement is one of the frequent features of gingival diseases. However due to their varied presentations, the diagnosis of these entities becomes challenging for the clinician. They can be categorized based on their etiopathogenesis, location, size, extent, etc. Based on the existing knowledge and clinical experience, a differential diagnosis can be formulated. Subsequently, after detailed investigation, clinician makes a final diagnosis or diagnosis of exclusion. A perfect diagnosis is critically important, since the management of these lesions and prevention of their recurrence is completely dependent on it. Furthermore, in some cases where gingival enlargement could be the primary sign of potentially lethal systemic diseases, a correct diagnosis of these enlargements could prove life saving for the patient or at least initiate early treatment and improve the quality of life. The purpose of this review article is to highlight significant findings of different types of gingival enlargement which would help clinician to differentiate between them. A detailed decision tree is also designed for the practitioners, which will help them arrive at a diagnosis in a systematic manner. There still could be some lesions which may present in an unusual manner and make the diagnosis challenging. By knowing the existence of common and rare presentations of gingival enlargement, one can keep a broad view when formulating a differential diagnosis of localized(isolated, discrete, regional) or generalized gingival enlargement.
基金the financial support received from the Program of Attraction and Insertion of Advanced Human Resources, MEC-Conicyt (80120014)
文摘The fibrous epulis, a common tumor-like lesion of the gingiva, appears in the interdental papilla as a result of local irritation. Lesions are asymptomatic and have a variable growth rate. A 75-year-old woman was referred for the evaluation of a large painless gingival mass. It had started 10 years back and has been increasing in size the last year. No bone involvement was noted. The tumor was totally removed by excision with surgical scalpel under local anesthesia without teeth extraction. The microscopic findings were suggestive of a fibrous epulis. Differential diagnosis, clinical considerations and factors to prevent recurrence are discussed.
文摘We present the case of a 45-year-old Hispanic female with a slowly enlarging mass on her left maxilla in the region of teeth #15 and #16. A differential diagnosis is presented along with the histologic findings and treatment rendered. The prognosis and biology of the lesion are discussed.
文摘目的检测富血小板纤维蛋白(PRF)膜与胶原膜修复拔牙术后牙龈缺损各时间节点的分泌物中钙结合蛋白和胶原酶-1的水平,评价PRF对牙龈缺损的修复和调节局部炎性反应的能力。方法选取2013年8月至2014年12月到成都军区机关医院种植修复临床专科中心就诊,需拔除磨牙并同期进行位点保存的患牙16例,随机分为PRF膜组和胶原膜组,各8例。拔牙后,牙槽窝内植入Bio-Oss骨替代材料,表面分别覆盖PRF膜或胶原膜。通过ELISA检测术区在术后3、7、14、21、28 d创面分泌物中胶原酶-1和钙结合蛋白的水平,动态评价PRF对牙龈缺损的修复和调节局部炎性反应的能力。结果钙结合蛋白水平在术后3、7 d胶原膜组均明显高于PRF膜组,差异均有统计学意义(P<0.05);术后14、21、28 d胶原膜组稍高于PRF膜组,但差异无统计学意义(P>0.05)。胶原酶-1水平在术后3、7 d PRF膜组均明显高于胶原膜组,差异均有统计学意义(P<0.05);术后14、21、28 d PRF组稍高于胶原膜组,差异均无统计学意义(P>0.05)。结论PRF能促进牙龈缺损的修复,减轻术区局部炎性反应。PRF膜是一种有一定抗感染能力的生物活性再生平台材料,有一定的临床价值。
