As is known, the Great Red Spot (GRS) is one of the most mysterious sights in the solar system and is a strong storm that is quite large. According to the laws of hydrodynamics and gas dynamics, it should have disappe...As is known, the Great Red Spot (GRS) is one of the most mysterious sights in the solar system and is a strong storm that is quite large. According to the laws of hydrodynamics and gas dynamics, it should have disappeared several centuries ago, but scientists still observe it and cannot accurately explain this phenomenon. Since turbulence and atmospheric waves in the GRS region absorb the energy of its winds, the vortex loses energy by radiating heat. In the work, it is proved with a mathematical and non-classical approach that the GRS and anticyclones will live for a long time;otherwise, we had to first of all prove that the vortex threads (loops) and ovals could not exist. Based on these supports, mathematical methods prove their existence forever by observing a large vortex (GRS);moreover, they are sources of heat. When proofs are obtained, the results are consistent with the previous hypotheses of the researcher. The introduction of the work gives a comparison of various hypotheses;for example, one of them states that the decrease in the size of the GRS is only an illusory observation. Next, we first consider the applicability conditions for the mathematical justification of the hypothesis of the longevity of the Great Red Spot. The wind equation and the GRS are energized by absorbing smaller eddies and ovals, and this total energy is constant. With the help of the KH mechanism in the case of Brunt Vaisala, the frequencies (which can be calculated by a program with given formulas) are determined using very strictly mathematical evidence to substantiate the validity of the hypothesis about the longevity of Jupiter’s Great Red Spot.展开更多
It has always been challenging to determine the ancient sedimentary environment and associated energy in deep-buried marine carbonates.The energy represents the hydrodynamic conditions that existed when the carbonates...It has always been challenging to determine the ancient sedimentary environment and associated energy in deep-buried marine carbonates.The energy represents the hydrodynamic conditions that existed when the carbonates were deposited.The energy includes light and chemical energies in compounds and kinetic energy in currents and mass flow.Deep-buried marine carbonates deposited during the Ordovician depositional period in the eastern Tarim Basin result from a complex interplay of tectonics,sedimentation,and diagenesis.As a result,determining the ancient sedimentary environment and associated energy is complex.The natural gamma-ray spectrometry(GRS)log(from 12 wells)is used in this paper to conduct studies on the sedimentary environment and associated energy in deep-buried marine carbonates.The findings show that the values of thorium(Th),uranium(U),potassium(K),and gamma-ray without uranium(KTh)in a natural GRS log can reveal lithological associations,mineral composition,diagenetic environment,stratigraphic water activity,and ancient climatic change.During the Ordovician,quantitative analysis and determination of sedimentary environment energy are carried out using a comprehensive calculation of natural GRS log parameters in typical wells(penetrating through the Ordovician with cores and thin sections)of well GC4,well GC6,well GC7,and well GC8.The results show that GRS log can determine different lithology associations in typical wells than a sieve residue log.Furthermore,cores and thin sections can be used to validate the determination of lithology associations.Based on the determination of lithology associations,the lithology associations that reflect the sedimentary environment and associated energy can be analyzed in a new approach.Furthermore,the sedimentary environment energy curve derived from a natural GRS log can reveal hydrodynamic fluctuations during depositional periods,which will aid in the discovery of carbonate reservoirs,establishing sequence stratigraphic frameworks,and the reconstruction of sea-le展开更多
In this paper, the case of Jupiter being found in hydrodynamic equilibrium is for the first time investigated solely by mathematical methods. With the help of the hydrodynamic method, formulas of energy balance for ov...In this paper, the case of Jupiter being found in hydrodynamic equilibrium is for the first time investigated solely by mathematical methods. With the help of the hydrodynamic method, formulas of energy balance for oval and vortex are found, which are summed as permanent kinetic energy and constantly provide equilibrium for the stable rotational movements of Jupiter. To find the total kinetic energy of the oval and vortex in turbulent mode, Green’s function methods with special definitions and flow functions that describe the movement of the vortex are applied. The results are expressed in lemmas and theorems. For the hydrodynamic equilibrium of Jupiter, the necessary and sufficient conditions for the preservation of the cyclone and the anticyclone are mentioned. The relationships between the angular velocity and the gradient of pressure and the Corolias parameter are also given. The Rossby number is given for steady rotational motion. These facts show the existence of necessary and sufficient conditions for maintaining the stability of rotational motion and prove the hydrodynamic equilibrium of Jupiter. In this case using stream function and constructing generalized Green’s function and accordance energy conservation laws, the hydrodynamic equilibrium of Jupiter is proved.展开更多
Background: Long standing aortic stenosis leads to elevated left ventricular (LV) pressure and as a result LV hypertrophy and myocardial fibrosis shall increase. The left ventricular ejection fraction (EF) usually rem...Background: Long standing aortic stenosis leads to elevated left ventricular (LV) pressure and as a result LV hypertrophy and myocardial fibrosis shall increase. The left ventricular ejection fraction (EF) usually remains adequately-preserved until advanced and late stages of aortic stenosis. But the preserved muscle of the LV is only limited to a portion of the entire myocardium. Speckle tracking echocardiography has proved its superiority to the standard two-dimensional echocardiography method in the detection of Left Ventricular (LV) function. Global Longitudinal strain (GLS) is considered as the most robust myocardial strain component.?Objective: The aim of the study is to assess the early course of left ventricular reverse remodelling after Transcutaneous Aortic Valve Implantation (TAVI) in patients with symptomatic severe aortic valve stenosis.?Methods: 50 patients with severe symptomatic valvular aortic stenosis undergoing TAVI as decided by the heart team after comprehensive discussion.?Standard transthoracic echocardiography including Doppler analysis was performed. 2D speckle-tracking strain assessment of Global radial, circumferential and longitudinal strain at parasternal mid-ventricular short-axis view (at the level of papillary muscle) and from the apical long-axis, two-chamber and four-chamber views with a frame rate between 40 and 80 frames per second. Tracing of endocardial borders was done. Patients with significant coronary artery disease were fully revascularized by percutaneous coronary intervention prior to the study and the procedure. Results: 23 (46%) patients were males, while 27 (54%) were females. The patients’ stratification according to comorbidities/associated risk factors revealed that 54% of the patients had DM, 86% were hypertensive, 38% had chronic kidney disease (CKD), and 32% had a previous percutaneous coronary intervention (PCI).?The mean age for our study participants ranged?from 60 to 92 years (Mean ± SD = 76.60 ± 5.96). Left ventricular diastolic diameter (LVDd) was 44展开更多
The quasi-periodic oscillations （QPOs） in black hole （BH） systems with different scales are interpreted based on the magnetic reconnection of large-scale mag- netic fields generated by toroidal electric currents f...The quasi-periodic oscillations （QPOs） in black hole （BH） systems with different scales are interpreted based on the magnetic reconnection of large-scale mag- netic fields generated by toroidal electric currents flowing in the inner region of the accretion disk, where the current density is assumed to be proportional to the mass density of the accreting plasma. The magnetic connection （MC） is taken into account in resolving dynamic equations describing the accretion disk, in which the MC be- tween the inner and outer disk regions, between the plunging region and the disk, and between the BH horizon and the disk are involved. It turns out that a single QPO frequency associated with several BH systems with different scales can be fitted by in- voking the magnetic reconnection due to the MC between the inner and outer regions of the disk, including the BH binaries XTE J1859＋226, XTE J1650-500 and GRS 1915＋105 and the massive BHs in NGC 5408 X-1 and RE J1034＋396. In addition, the X-ray spectra corresponding to the QPOs for these sources are fitted based on the typical disk-corona model.展开更多
The rms-flux relations for some observations of GRS 1915+105 are studied.The rms-flux relations of the light curves in only one state,state C or state A,can be described by the simple non-linear model provided Zhang;w...The rms-flux relations for some observations of GRS 1915+105 are studied.The rms-flux relations of the light curves in only one state,state C or state A,can be described by the simple non-linear model provided Zhang;we thus interpret that such a linear relation reflects the relative importance of magnetic instability for X-ray emission in the corona of the system,compared to the thermal viscous instability for the X-ray emission in the accretion disk.The rms-flux relations for state B are very scattered,possibly because of the dominance of thermal viscous instability for the X-ray emission in the accretion disk.The complex rms-flux relations for the observations of transitions between two or three states are caused by the combination of the different rms-flux relations of these states.The underlying physical processes are the combination of magnetic topology in the corona and thermal viscous instability in the accretion disk.展开更多
目的构建疾病的遗传风险评分,为健康指数的构建提供有力工具。方法利用英国生物银行(UK Biobank,UKB)数据库,以2型糖尿病为例,利用经典方法、LDpred和DBSLMM方法构建疾病的遗传风险评分,评价这三种方法构建的遗传风险评分对于2型糖尿病...目的构建疾病的遗传风险评分,为健康指数的构建提供有力工具。方法利用英国生物银行(UK Biobank,UKB)数据库,以2型糖尿病为例,利用经典方法、LDpred和DBSLMM方法构建疾病的遗传风险评分,评价这三种方法构建的遗传风险评分对于2型糖尿病发病的预测能力。结果队列共纳入271282人,其中6047人发生2型糖尿病。三种方法曲线下面积(areas under the curve,AUC)(95%CI)分别为0.699(0.692~0.705)、0.747(0.741~0.753)和0.745(0.739~0.751)。与经典方法相比,后两种方法的AUC分别提高了4.8%、4.6%,差异均有统计学意义(均有P<0.001)。以低遗传风险组作为参照,三种方法高风险组的HR(95%CI)分别为2.42(2.26~2.59)、4.43(4.11~4.77)和4.49(4.16~4.84)。结论DBSLMM法构建的遗传风险评分对于2型糖尿病发病风险有较好的预测能力,为其他疾病健康指数中遗传部分的构建提供了方法支撑。展开更多
A new fit of the pion parton distribution functions is provided. Only valence quark distributions are used at a low evolution scale and are evolved with the modified Dokshitzer- Gribov-Lipatov-Altarelli-Parisi equatio...A new fit of the pion parton distribution functions is provided. Only valence quark distributions are used at a low evolution scale and are evolved with the modified Dokshitzer- Gribov-Lipatov-Altarelli-Parisi equation which is briefly introduced in this work, and the sea quark and gluon distributions are only generated by the quantum chromodynamics processes. We find that the patton distributions can explain the pion-nucleon experiments data well, and it can also be compared with the data from the leading neutron data of experiments at HERA. The momentum distributions among the partons are discussed and our results are consistent with some models.展开更多
Brain transcriptional regulatory network for behavior demonstrates that brain gene expression in the honey bee can be accurately predicted from the expression transcription factors(TFs),but roles for specific TFs are ...Brain transcriptional regulatory network for behavior demonstrates that brain gene expression in the honey bee can be accurately predicted from the expression transcription factors(TFs),but roles for specific TFs are less understood.Mushroom bodies(MBs)are important for learning,memory and sensory integration in the honey bee brain.A TFs,Mblk-1,expressed preferentially in the large-type Kenyon cells of the honeybee MBs is predicted to be involved in brain function by regulating transcription of its target genes in honey bee.However,its function and the mechanism of regulation in behavior of honey bee is still obscure.Here we show that Mblk-1 had significantly higher expression in the brains of forager bees relative to nurse bees.Mblk-1 was significantly inhibited in bees fed small interfering RNA.In addition,inhibition of Mblk-1 decreased sucrose responsiveness in foragers.Finally,we determined that Mblk-1 regulated the messenger RNA of AmGRl.These findings suggest that Mblk-1 may target AmGRl to regulate the sucrose responsiveness of foragers.展开更多
文摘As is known, the Great Red Spot (GRS) is one of the most mysterious sights in the solar system and is a strong storm that is quite large. According to the laws of hydrodynamics and gas dynamics, it should have disappeared several centuries ago, but scientists still observe it and cannot accurately explain this phenomenon. Since turbulence and atmospheric waves in the GRS region absorb the energy of its winds, the vortex loses energy by radiating heat. In the work, it is proved with a mathematical and non-classical approach that the GRS and anticyclones will live for a long time;otherwise, we had to first of all prove that the vortex threads (loops) and ovals could not exist. Based on these supports, mathematical methods prove their existence forever by observing a large vortex (GRS);moreover, they are sources of heat. When proofs are obtained, the results are consistent with the previous hypotheses of the researcher. The introduction of the work gives a comparison of various hypotheses;for example, one of them states that the decrease in the size of the GRS is only an illusory observation. Next, we first consider the applicability conditions for the mathematical justification of the hypothesis of the longevity of the Great Red Spot. The wind equation and the GRS are energized by absorbing smaller eddies and ovals, and this total energy is constant. With the help of the KH mechanism in the case of Brunt Vaisala, the frequencies (which can be calculated by a program with given formulas) are determined using very strictly mathematical evidence to substantiate the validity of the hypothesis about the longevity of Jupiter’s Great Red Spot.
基金then the authors gratefully acknowledge financial support from the Key Droject the National Natural Foundation of China(No.42330810)the National Natural Science Foundation of China(Grant No.U19B6003-01-01)the State Key Program of the National Natural Science Foundation of China(No.41130422).
文摘It has always been challenging to determine the ancient sedimentary environment and associated energy in deep-buried marine carbonates.The energy represents the hydrodynamic conditions that existed when the carbonates were deposited.The energy includes light and chemical energies in compounds and kinetic energy in currents and mass flow.Deep-buried marine carbonates deposited during the Ordovician depositional period in the eastern Tarim Basin result from a complex interplay of tectonics,sedimentation,and diagenesis.As a result,determining the ancient sedimentary environment and associated energy is complex.The natural gamma-ray spectrometry(GRS)log(from 12 wells)is used in this paper to conduct studies on the sedimentary environment and associated energy in deep-buried marine carbonates.The findings show that the values of thorium(Th),uranium(U),potassium(K),and gamma-ray without uranium(KTh)in a natural GRS log can reveal lithological associations,mineral composition,diagenetic environment,stratigraphic water activity,and ancient climatic change.During the Ordovician,quantitative analysis and determination of sedimentary environment energy are carried out using a comprehensive calculation of natural GRS log parameters in typical wells(penetrating through the Ordovician with cores and thin sections)of well GC4,well GC6,well GC7,and well GC8.The results show that GRS log can determine different lithology associations in typical wells than a sieve residue log.Furthermore,cores and thin sections can be used to validate the determination of lithology associations.Based on the determination of lithology associations,the lithology associations that reflect the sedimentary environment and associated energy can be analyzed in a new approach.Furthermore,the sedimentary environment energy curve derived from a natural GRS log can reveal hydrodynamic fluctuations during depositional periods,which will aid in the discovery of carbonate reservoirs,establishing sequence stratigraphic frameworks,and the reconstruction of sea-le
文摘In this paper, the case of Jupiter being found in hydrodynamic equilibrium is for the first time investigated solely by mathematical methods. With the help of the hydrodynamic method, formulas of energy balance for oval and vortex are found, which are summed as permanent kinetic energy and constantly provide equilibrium for the stable rotational movements of Jupiter. To find the total kinetic energy of the oval and vortex in turbulent mode, Green’s function methods with special definitions and flow functions that describe the movement of the vortex are applied. The results are expressed in lemmas and theorems. For the hydrodynamic equilibrium of Jupiter, the necessary and sufficient conditions for the preservation of the cyclone and the anticyclone are mentioned. The relationships between the angular velocity and the gradient of pressure and the Corolias parameter are also given. The Rossby number is given for steady rotational motion. These facts show the existence of necessary and sufficient conditions for maintaining the stability of rotational motion and prove the hydrodynamic equilibrium of Jupiter. In this case using stream function and constructing generalized Green’s function and accordance energy conservation laws, the hydrodynamic equilibrium of Jupiter is proved.
文摘Background: Long standing aortic stenosis leads to elevated left ventricular (LV) pressure and as a result LV hypertrophy and myocardial fibrosis shall increase. The left ventricular ejection fraction (EF) usually remains adequately-preserved until advanced and late stages of aortic stenosis. But the preserved muscle of the LV is only limited to a portion of the entire myocardium. Speckle tracking echocardiography has proved its superiority to the standard two-dimensional echocardiography method in the detection of Left Ventricular (LV) function. Global Longitudinal strain (GLS) is considered as the most robust myocardial strain component.?Objective: The aim of the study is to assess the early course of left ventricular reverse remodelling after Transcutaneous Aortic Valve Implantation (TAVI) in patients with symptomatic severe aortic valve stenosis.?Methods: 50 patients with severe symptomatic valvular aortic stenosis undergoing TAVI as decided by the heart team after comprehensive discussion.?Standard transthoracic echocardiography including Doppler analysis was performed. 2D speckle-tracking strain assessment of Global radial, circumferential and longitudinal strain at parasternal mid-ventricular short-axis view (at the level of papillary muscle) and from the apical long-axis, two-chamber and four-chamber views with a frame rate between 40 and 80 frames per second. Tracing of endocardial borders was done. Patients with significant coronary artery disease were fully revascularized by percutaneous coronary intervention prior to the study and the procedure. Results: 23 (46%) patients were males, while 27 (54%) were females. The patients’ stratification according to comorbidities/associated risk factors revealed that 54% of the patients had DM, 86% were hypertensive, 38% had chronic kidney disease (CKD), and 32% had a previous percutaneous coronary intervention (PCI).?The mean age for our study participants ranged?from 60 to 92 years (Mean ± SD = 76.60 ± 5.96). Left ventricular diastolic diameter (LVDd) was 44
基金supported by the National Natural Science Foundation of China (Grant Nos. 11173011, 11143001, 11103003 and 11045004)the National Basic Research Program of China (973 program, 2009CB824800)the Fundamental Research Funds for the Central Universities (HUST: 2011TS159)
文摘The quasi-periodic oscillations （QPOs） in black hole （BH） systems with different scales are interpreted based on the magnetic reconnection of large-scale mag- netic fields generated by toroidal electric currents flowing in the inner region of the accretion disk, where the current density is assumed to be proportional to the mass density of the accreting plasma. The magnetic connection （MC） is taken into account in resolving dynamic equations describing the accretion disk, in which the MC be- tween the inner and outer disk regions, between the plunging region and the disk, and between the BH horizon and the disk are involved. It turns out that a single QPO frequency associated with several BH systems with different scales can be fitted by in- voking the magnetic reconnection due to the MC between the inner and outer regions of the disk, including the BH binaries XTE J1859＋226, XTE J1650-500 and GRS 1915＋105 and the massive BHs in NGC 5408 X-1 and RE J1034＋396. In addition, the X-ray spectra corresponding to the QPOs for these sources are fitted based on the typical disk-corona model.
基金support by the National Basic Research Program of China (Grant No. 2009CB824800)the Directional Research Project of the Chinese Academy of Sciences (Grant No. KJCX2-YW-T03)the National Natural Science Foundation of China (Grant Nos. 10821061,10733010,and 10725313)
文摘The rms-flux relations for some observations of GRS 1915+105 are studied.The rms-flux relations of the light curves in only one state,state C or state A,can be described by the simple non-linear model provided Zhang;we thus interpret that such a linear relation reflects the relative importance of magnetic instability for X-ray emission in the corona of the system,compared to the thermal viscous instability for the X-ray emission in the accretion disk.The rms-flux relations for state B are very scattered,possibly because of the dominance of thermal viscous instability for the X-ray emission in the accretion disk.The complex rms-flux relations for the observations of transitions between two or three states are caused by the combination of the different rms-flux relations of these states.The underlying physical processes are the combination of magnetic topology in the corona and thermal viscous instability in the accretion disk.
文摘目的构建疾病的遗传风险评分,为健康指数的构建提供有力工具。方法利用英国生物银行(UK Biobank,UKB)数据库,以2型糖尿病为例,利用经典方法、LDpred和DBSLMM方法构建疾病的遗传风险评分,评价这三种方法构建的遗传风险评分对于2型糖尿病发病的预测能力。结果队列共纳入271282人,其中6047人发生2型糖尿病。三种方法曲线下面积(areas under the curve,AUC)(95%CI)分别为0.699(0.692~0.705)、0.747(0.741~0.753)和0.745(0.739~0.751)。与经典方法相比,后两种方法的AUC分别提高了4.8%、4.6%,差异均有统计学意义(均有P<0.001)。以低遗传风险组作为参照,三种方法高风险组的HR(95%CI)分别为2.42(2.26~2.59)、4.43(4.11~4.77)和4.49(4.16~4.84)。结论DBSLMM法构建的遗传风险评分对于2型糖尿病发病风险有较好的预测能力,为其他疾病健康指数中遗传部分的构建提供了方法支撑。
文摘A new fit of the pion parton distribution functions is provided. Only valence quark distributions are used at a low evolution scale and are evolved with the modified Dokshitzer- Gribov-Lipatov-Altarelli-Parisi equation which is briefly introduced in this work, and the sea quark and gluon distributions are only generated by the quantum chromodynamics processes. We find that the patton distributions can explain the pion-nucleon experiments data well, and it can also be compared with the data from the leading neutron data of experiments at HERA. The momentum distributions among the partons are discussed and our results are consistent with some models.
基金This work was supported by the Natural Science Foundation of Guangdong Province(2021A1515010630,2021A1515012102)GDAS Special Project of Science and Technology Development(2021GDASYL-20210103053)China Agriculture Research System(CARS-44-SYZ11).
文摘Brain transcriptional regulatory network for behavior demonstrates that brain gene expression in the honey bee can be accurately predicted from the expression transcription factors(TFs),but roles for specific TFs are less understood.Mushroom bodies(MBs)are important for learning,memory and sensory integration in the honey bee brain.A TFs,Mblk-1,expressed preferentially in the large-type Kenyon cells of the honeybee MBs is predicted to be involved in brain function by regulating transcription of its target genes in honey bee.However,its function and the mechanism of regulation in behavior of honey bee is still obscure.Here we show that Mblk-1 had significantly higher expression in the brains of forager bees relative to nurse bees.Mblk-1 was significantly inhibited in bees fed small interfering RNA.In addition,inhibition of Mblk-1 decreased sucrose responsiveness in foragers.Finally,we determined that Mblk-1 regulated the messenger RNA of AmGRl.These findings suggest that Mblk-1 may target AmGRl to regulate the sucrose responsiveness of foragers.
