OBJECTIVE: To evaluate the clinical efficacy and safety of five phase music therapy in patients with depression after ischemic stroke.METHODS: A total of 92 patients with post-stroke depression were randomly divided i...OBJECTIVE: To evaluate the clinical efficacy and safety of five phase music therapy in patients with depression after ischemic stroke.METHODS: A total of 92 patients with post-stroke depression were randomly divided into the control group(32 cases), treatment group A(30 cases), and treatment group B(30 cases). All groups were given basic therapies for cerebral infarction. In addition,the control group was administerd 50 mg of oral sertraline hydrochloride daily, while treatment groups A and B received needling at Baihui(GV 20)plus acupoint injection at Yanglingquan(GB 34) daily; treatment group B also received music therapy derived from the five phases in Traditional ChineseMedicine theory twice daily. All treatments were administered for 5 d per treatment cycle for three cycles, with a 1 d interval between cycles. In all three groups, Hamilton's depression scale(HAMD-17)score and the activities of daily life(ADL) score were measured before and after treatment, and side effects were assessed with the treatment emergent symptom scale.RESULTS: The HAMD-17 score significantly decreased after treatment in all three groups, and the post-treatment reduction in HAMD-17 score was markedly greater in treatment group B than in treatment group A(P < 0.01). The ADL score significantly increased after treatment in all three groups,and the post-treatment increase in ADL score was significantly greater in treatment group B than in treatment group A(P < 0.01). The treatment emergent symptom scale score was highest in the control group, and lowest in group B, and significantly differed between the three groups(P < 0.01).CONCLUSION: Five phase music therapy plus acupoint needling and acupoint injection can improve the symptoms in patients with post-stroke depression.展开更多
基金Supported by State Administration of Traditional Chinese Medicine of the People's Republic of China,State Clinical Research Base of Traditional Chinese Medicine,The Second Batch of Professional Skill Scientific and Research Special Project(No.JDZX2015127)Jiangsu Natural Science Foundation Youth Project(No.BK20171070)Nanjing Scientific Development Planned Project(No.201402057)
文摘OBJECTIVE: To evaluate the clinical efficacy and safety of five phase music therapy in patients with depression after ischemic stroke.METHODS: A total of 92 patients with post-stroke depression were randomly divided into the control group(32 cases), treatment group A(30 cases), and treatment group B(30 cases). All groups were given basic therapies for cerebral infarction. In addition,the control group was administerd 50 mg of oral sertraline hydrochloride daily, while treatment groups A and B received needling at Baihui(GV 20)plus acupoint injection at Yanglingquan(GB 34) daily; treatment group B also received music therapy derived from the five phases in Traditional ChineseMedicine theory twice daily. All treatments were administered for 5 d per treatment cycle for three cycles, with a 1 d interval between cycles. In all three groups, Hamilton's depression scale(HAMD-17)score and the activities of daily life(ADL) score were measured before and after treatment, and side effects were assessed with the treatment emergent symptom scale.RESULTS: The HAMD-17 score significantly decreased after treatment in all three groups, and the post-treatment reduction in HAMD-17 score was markedly greater in treatment group B than in treatment group A(P < 0.01). The ADL score significantly increased after treatment in all three groups,and the post-treatment increase in ADL score was significantly greater in treatment group B than in treatment group A(P < 0.01). The treatment emergent symptom scale score was highest in the control group, and lowest in group B, and significantly differed between the three groups(P < 0.01).CONCLUSION: Five phase music therapy plus acupoint needling and acupoint injection can improve the symptoms in patients with post-stroke depression.
文摘目的:探讨电针足少阳经穴在膝关节前交叉韧带(anterior cruciate ligament,ACL)损伤术后康复中的应用价值。方法:纳入膝关节ACL部分损伤患者50例。由同一组医生行膝关节镜下腓骨长肌腱单束ACL重建术,术后第2天开始电针患侧足少阳经的悬钟、阳陵泉、膝阳关、环跳4穴。每天1次,连续治疗6d为1个疗程,2个疗程间隔1d,共治疗6个疗程。比较治疗前及治疗开始后2周、4周、6周时双侧膝关节的被动活动察觉阈值(threshold to detection of passive motion,TTDPM)、关节位置觉(joint position sense,JPS)以及体感诱发电位(somatosensory evoked potentials,SEPs)P40起始潜伏期、波幅和运动神经传导速度(motor nerve conduction velocity,MCV)潜伏期、波幅。结果:①TTDPM。时间因素和分组因素存在交互效应(F=312.586,P=0.000)。双侧膝关节TTDPM总体比较,差异有统计学意义,即存在分组效应(F=406.942,P=0.000)。治疗前后不同时间点间膝关节TTDPM的差异有统计学意义,即存在时间效应(F=334.592,P=0.000)。患侧膝关节TTDPM随时间呈下降趋势(3.57°±0.53°,2.61°±0.47°,2.21°±0.39°,1.92°±0.28°,F=349.201,P=0.000),健侧随时间无明显变化(1.44°±0.10°,1.42°±0.12°,1.40°±0.10°,1.41°±0.07°,F=2.772,P=0.052)。治疗前后各时间点,患侧膝关节TTDPM均较健侧高(t=29.528,P=0.000;t=21.642,P=0.000;t=16.658,P=0.000;t=13.642,P=0.000)。②JPS。时间因素和分组因素存在交互效应(F=201.439,P=0.000)。双侧膝关节JPS总体比较,差异有统计学意义,即存在分组效应(F=532.141,P=0.000)。治疗前后不同时间点间膝关节JPS的差异有统计学意义,即存在时间效应(F=209.843,P=0.000)。患侧膝关节JPS随时间呈改善趋势(4.31°±0.71°,3.62°±0.65°,3.23°±0.60°,2.64°±0.54°,F=211.272,P=0.000),健侧随时间无明显变化(1.49°±0.13°,1.47°±0.11°,1.48°±0.10°,1.47°±0.10°,F=1.333,P=0.277)。治疗前后各时间点,患侧膝关节JPS均较健侧差(t=28.782,P=0.00
