AIM:To study the constituents of Forsythia suspensa(Thunb.) Vahl and find out the bioactive compounds.METHODS:The chemical constituents were isolated by various column chromatographic methods and the structures of the...AIM:To study the constituents of Forsythia suspensa(Thunb.) Vahl and find out the bioactive compounds.METHODS:The chemical constituents were isolated by various column chromatographic methods and the structures of the compounds were elucidated by spectral analysis.RESULTS:Nine compounds were obtained from acetic ester extracts of Forsythia suspensa(Thunb.)Vahl and their structures were identified as phillygenin(Ⅰ),epipinoresinol(Ⅱ),phillyrin(Ⅲ),(-)isolarlci-resinol(Ⅳ),betulinic acid(Ⅴ),2α-hydroxy betulinic acid(Ⅵ),oleanolic acid(Ⅶ),ursolic acid(Ⅷ) and 2α,23-hydroxy ursolic acid(Ⅸ)from the EtoAc extract.CONCLUSION:Compounds Ⅵ and Ⅸ are isolated from this plant and this genus for the first time.展开更多
目的研究中药连翘的化学成分。方法采用硅胶吸附柱色谱的手段 ,利用理化和谱学分析(NMR、ESI MS)方法 ,对化合物进行分离鉴定。结果从连翘的果实中分离得到一个化合物 ,确定其结构 ,将其命名为连翘酸 1′ O β D 葡萄糖苷 (rengynicaci...目的研究中药连翘的化学成分。方法采用硅胶吸附柱色谱的手段 ,利用理化和谱学分析(NMR、ESI MS)方法 ,对化合物进行分离鉴定。结果从连翘的果实中分离得到一个化合物 ,确定其结构 ,将其命名为连翘酸 1′ O β D 葡萄糖苷 (rengynicacid 1′ O β D glucoside)。展开更多
文摘AIM:To study the constituents of Forsythia suspensa(Thunb.) Vahl and find out the bioactive compounds.METHODS:The chemical constituents were isolated by various column chromatographic methods and the structures of the compounds were elucidated by spectral analysis.RESULTS:Nine compounds were obtained from acetic ester extracts of Forsythia suspensa(Thunb.)Vahl and their structures were identified as phillygenin(Ⅰ),epipinoresinol(Ⅱ),phillyrin(Ⅲ),(-)isolarlci-resinol(Ⅳ),betulinic acid(Ⅴ),2α-hydroxy betulinic acid(Ⅵ),oleanolic acid(Ⅶ),ursolic acid(Ⅷ) and 2α,23-hydroxy ursolic acid(Ⅸ)from the EtoAc extract.CONCLUSION:Compounds Ⅵ and Ⅸ are isolated from this plant and this genus for the first time.
文摘目的研究中药连翘的化学成分。方法采用硅胶吸附柱色谱的手段 ,利用理化和谱学分析(NMR、ESI MS)方法 ,对化合物进行分离鉴定。结果从连翘的果实中分离得到一个化合物 ,确定其结构 ,将其命名为连翘酸 1′ O β D 葡萄糖苷 (rengynicacid 1′ O β D glucoside)。
