Diabetic foot ulcer(DFU) is the most costly and devastating complication of diabetes mellitus, which affect 15% of diabetic patients during their lifetime.Based on National Institute for Health and Clinical Excellence...Diabetic foot ulcer(DFU) is the most costly and devastating complication of diabetes mellitus, which affect 15% of diabetic patients during their lifetime.Based on National Institute for Health and Clinical Excellence strategies, early effective management of DFU can reduce the severity of complications such as preventable amputations and possible mortality, and also can improve overall quality of life. The management of DFU should be optimized by using a multidisciplinary team, due to a holistic approach to wound management is required. Based on studies, blood sugar control, wound debridement, advanced dressings and offloading modalities should always be a part of DFU management. Furthermore, surgery to heal chronic ulcer and prevent recurrence should be considered as an essential component of management in some cases. Also, hyperbaric oxygen therapy, electrical stimulation, negative pressure wound therapy, bio-engineered skin and growth factors could be used as adjunct therapies for rapid healing of DFU. So, it's suggested that with appropriate patient education encourages them to regular foot care in order to prevent DFU and its complications.展开更多
目的系统地分析、评价糖尿病足发病风险预测模型,以期为护理实践提供参考依据。方法检索PubMed、Embase、Web of Science、Cochrane图书馆、中国生物医学文献数据库、中国知网和万方数据库中有关糖尿病足发病风险预测模型的研究,检索时...目的系统地分析、评价糖尿病足发病风险预测模型,以期为护理实践提供参考依据。方法检索PubMed、Embase、Web of Science、Cochrane图书馆、中国生物医学文献数据库、中国知网和万方数据库中有关糖尿病足发病风险预测模型的研究,检索时限为建库至2020年3月1日。由2名研究者独立筛选文献和提取数据,并应用预测模型研究的偏倚风险评估工具分析纳入文献的偏倚风险和适用性。结果共纳入7项糖尿病足发病风险预测模型研究,包括6项开发研究和1项验证研究。7个模型的受试者工作特征曲线下面积为0.65~0.88。所有纳入模型中包含最多的预测因子是单丝试验不敏感。7项研究的适用性较好,但存在一定的偏倚,主要是因为未采取或未报告盲法、应变量事件数不足、忽略缺失数据、缺乏模型性能评估以及模型过度拟合。结论糖尿病足发病风险预测模型的研究还处于发展阶段,未来应开发性能优良、偏倚风险低的预测模型,并进行内部验证或外部验证。展开更多
基金Supported by Health Research Institute,Diabetes Research Center,Ahvaz Jundishapur University of Medical Sciences,Ahvaz,Iran
文摘Diabetic foot ulcer(DFU) is the most costly and devastating complication of diabetes mellitus, which affect 15% of diabetic patients during their lifetime.Based on National Institute for Health and Clinical Excellence strategies, early effective management of DFU can reduce the severity of complications such as preventable amputations and possible mortality, and also can improve overall quality of life. The management of DFU should be optimized by using a multidisciplinary team, due to a holistic approach to wound management is required. Based on studies, blood sugar control, wound debridement, advanced dressings and offloading modalities should always be a part of DFU management. Furthermore, surgery to heal chronic ulcer and prevent recurrence should be considered as an essential component of management in some cases. Also, hyperbaric oxygen therapy, electrical stimulation, negative pressure wound therapy, bio-engineered skin and growth factors could be used as adjunct therapies for rapid healing of DFU. So, it's suggested that with appropriate patient education encourages them to regular foot care in order to prevent DFU and its complications.
文摘目的系统地分析、评价糖尿病足发病风险预测模型,以期为护理实践提供参考依据。方法检索PubMed、Embase、Web of Science、Cochrane图书馆、中国生物医学文献数据库、中国知网和万方数据库中有关糖尿病足发病风险预测模型的研究,检索时限为建库至2020年3月1日。由2名研究者独立筛选文献和提取数据,并应用预测模型研究的偏倚风险评估工具分析纳入文献的偏倚风险和适用性。结果共纳入7项糖尿病足发病风险预测模型研究,包括6项开发研究和1项验证研究。7个模型的受试者工作特征曲线下面积为0.65~0.88。所有纳入模型中包含最多的预测因子是单丝试验不敏感。7项研究的适用性较好,但存在一定的偏倚,主要是因为未采取或未报告盲法、应变量事件数不足、忽略缺失数据、缺乏模型性能评估以及模型过度拟合。结论糖尿病足发病风险预测模型的研究还处于发展阶段,未来应开发性能优良、偏倚风险低的预测模型,并进行内部验证或外部验证。
