Objectives: To evaluate the effects of the Chinese medicine (CM) five-element music on quality of life for senior and non-senior advanced cancer patients. Methods: With a randomized controlled trial, 170 advanced ...Objectives: To evaluate the effects of the Chinese medicine (CM) five-element music on quality of life for senior and non-senior advanced cancer patients. Methods: With a randomized controlled trial, 170 advanced cancer patients were randomly assigned to three groups: the CM five-element music group (68 patients), the Western music therapy group (68 cases), and the no music therapy group (34 cases). All patients of 70 years old or older were considered seniors and the remaining patients younger than 70 years were considered non- seniors. Patients in the CM five-element music group listened to CM five-element music, the patients in the Western music group listened to Western music, and the patients in the no music group did not listen to music. A course of treatment was 3 weeks, with 30 rain each day, 5 days a week. The Hospice Quality of Life Index- Revised (HQOLI-R) and Karnofsky performance score (KPS) were measured in the three groups before and after treatment. The symptom diary score was measured in the three groups every 3 days, 7 times in total. Results: CM five-element music group showed a significant difference of HQOLI-R, KPS and symptom diary score with other groups (all P〈0.01). There were significant differences of HQOLI-R, symptom diary score, and KPS after treatment in CM five-element music group and other groups in the non-senior subgroup (P〈0.05). Additionally, there were significant differences in HQOLI-R and KPS after treatment among the three groups in the senior subgroup (P〈0.05). Conclusions: CM five-element music therapy could improve the quality of life and KPS for senior and non senior advanced cancer patients, and it could improve subjective symptoms for non-senior advanced cancer patients.展开更多
Objective: To investigate the effects and mechanisms of Gong-tone music on the immunological function in rats with the Chinese medicine syndrome of Liver (Gan)-qi stagnation and Spleen (Pi)-qi deficiency (LSSD)...Objective: To investigate the effects and mechanisms of Gong-tone music on the immunological function in rats with the Chinese medicine syndrome of Liver (Gan)-qi stagnation and Spleen (Pi)-qi deficiency (LSSD). Methods: Twenty five male Wistar rats of SPF grade were randomly divided into 5 groups: normal group, model group, Xiaoyao Powder (逍遥散) group, Gong-tone group and combined group (the combination of Gong-tone and Xiaoyao Powder), with 5 rats in each group. The rat model for the Chinese medicine syndrome of LSSD was induced by chronic bandage and irregular diet. The course of treatment was 21 days. After the treatment, the levels of serum gastrin and IgG were detected by enzyme-linked immunoabsorbent assay (ELISA). Phagocytosis of macrophages was detected by the neutral red uptake assay and T cell proliferation was investigated by 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) assay. Results: The serum gastrin, macrophage phagocytosis, IgG level and proliferation ability of T cells in the model group were significantly decreased compared with those in the normal group (P〈0.05). Compared with those in the model group, the serum levels of gastrin, macrophage phagocytosis, IgG level and proliferation ability of T cells in Gong-tone, Xiaoyao Powder, and combined groups were significantly increased (P〈0.05). The combined group was superior to either Gong-tone group or Xiaoyao Powder group. Conclusion: Gong-tone music may upregulate the immunological function and play a role in adjuvant therapy in the Chinese syndrome of LSSD.展开更多
OBJECTIVE: To explore the effects of five-element music therapy on elderly patients with seasonal affective disorder in a Chinese nursing home.METHODS: The patients(n=50) were recruited from a Shijingshan district nur...OBJECTIVE: To explore the effects of five-element music therapy on elderly patients with seasonal affective disorder in a Chinese nursing home.METHODS: The patients(n=50) were recruited from a Shijingshan district nursing home in Beijing,China. They were randomly assigned to two groups, a treatment group and a control group,with 25 participants in each group. The patients received music therapy for 1-2 h each week over an8-week period. The music therapy involved four phases: introduction, activities, listening to the Chinese five-element music, and a concluding phase.The participants in the control group did not listen to the five-element music. This study consisted of two parts:(a) a qualitative study that used focus groups to understand the feelings of the patients with seasonal affective disorder;(b) a quantitative study that involved administration of the self-rating depression scale(SDS) and Hamilton depression scale(HAMD) before and after treatment.RESULTS:(a) Qualitative analysis results: strength derived from the five-element group music therapy and emotional adjustment. The five-element group music therapy can reduce patients' psychological distress and let them feel inner peace and enhance their life satisfaction.(b) No significant difference in SDS and HAMD scores was found between the two groups(P>0.05) prior to treatment. After treatment,the mean SDS score of the control group was 49.9±18.8, while the treatment group's score was 40.2±18.1. The HAMD score of the control group was11.2±3.1, and the treatment group's score was 8.8±4.9. Following 8 weeks of music therapy, the SDS and HAMD scores of the treatment group were significantly lower than those for the control group(P<0.05).CONCLUSION: Five-element music therapy alleviated the symptoms of seasonal affective disorder in the elderly patients.展开更多
Traditional Chinese medicine(TCM) plays an important role in the medical system used in health care and treatment of diseases.This article reviews the basic theory of TCM based on its formation and contributions.Two n...Traditional Chinese medicine(TCM) plays an important role in the medical system used in health care and treatment of diseases.This article reviews the basic theory of TCM based on its formation and contributions.Two new personal points are proposed as follows:Six Zang(六脏) theory and deemphasization of the five-element theory.The basic theory of Chinese herbs is also discussed.展开更多
Background:Many original studies have shown that traditional Chinese five-element therapy(FEM-therapy)can effectively relieve anxiety,depression and quality of life.However,one published systematic review refuted this...Background:Many original studies have shown that traditional Chinese five-element therapy(FEM-therapy)can effectively relieve anxiety,depression and quality of life.However,one published systematic review refuted this conclusion.To further clarify the efficacy of FEM therapy in relieving negative emotion among cancer patients and to assess the reliability of the evidence,this systematic review and meta-analysis was performed.Methods:We searched for randomized controlled trials(RCTs)comparing FEM-therapy versus standard care for cancer patients,six databases(CBM,PubMed,Cochrane Library,Web of Science,CNKI,and WanFang),two clinical trial registries and one gray literature database were searched from inception to October 31,2022.Two investigators independently screened literature,extracted data,and assessed risk of bias according to the Cochrane Handbook Version 6.1.0.The RevMan 5.3 software was used to perform the meta-analysis.Overall quality of evidence was rated using GRADE(Grading of Recommendations,Assessment,Development and Evaluation).Results:25 RCTs involving 1990 patients were finally included.Two of which had high risk bias,the remaining 23 were rated as unclear risk bias.Compared with other treatments,FEM-therapy combined with conventional nursing can significantly relieve anxiety(MD=-10.33,95%CI:[-13.77,-6.88],P<0.05;very low certainty)and depression(SMD=-1.10,95%CI:[-1.41,-0.79],P<0.05;very low certainty),and can significantly increase the quality of sleep(MD=-2.92,95%CI:[-4.89,-0.95],P<0.05;low certainty).Compared with acupuncture intervention,FEM-therapy combined with acupuncture can decreased the anxiety(SMD=-0.64,95%CI:[-0.98,-0.30],P<0.05;Moderate certainty)and depression(SMD=-0.68,95%CI:[-1.00,-0.32],P<0.05;Moderate certainty).Conclusion:Traditional Chinese FEM therapy combined with other treatments are effective in alleviating negative emotions among cancer patients.In order to better improve the quality of life of cancer patients and give more reliable advice,more trials of direct comparisons a展开更多
Objective:To investigate the neural mechanism of Gong tone matching to the five colors.Methods:The experiment was designed using event-related potential technique,following the S1 →S2 paradigm,and dividing into two a...Objective:To investigate the neural mechanism of Gong tone matching to the five colors.Methods:The experiment was designed using event-related potential technique,following the S1 →S2 paradigm,and dividing into two arms according to the Gong tone being played in harmonics or open strings.For each arm,S1 was the playing of the Gong tone,followed by S2,where subjects,based on their first reaction,were required to make a yes/no judgement to whether the tone matches to a randomly-picked color out of the five colors.During this process,the event-related potentials were recorded.Results:Gong tone played in harmonics,most participants matched it with black and cyan;while in the open strings arm,most matched it with black.The average amplitudes of P300 at PZ,FZ,and CZ points were compared.For the Gong tone played in harmonics,there was a significant difference between those who matched it with black and those who did otherwise (P <.01).There was also a significant difference between those who matched it with cyan and those who did otherwise (P <.01).For the open strings arm,there was a significant difference between those who matched it with black and those who did otherwise (P <.01).Conclusion:Our comparison of the average amplitudes of P300 suggests a commonality in the neural mechanism underlying categorical thinking that is not fundamentally altered by playing style.However,behavioral theory suggests that playing style does have an influence on categorization.The Gong tone can be matched with any of the five colors,which accords with the thought of central Earth in the five-element theory.This provides evidence of the similarity within five elements correspondences existing alongside the indirect matching between five tones and five colors.展开更多
基金Supported by the project of Chinese Geriatric Oncology Society of the"Eleventh five-year"Plan of Ministry of Civil Affairs(No.2008-47-2-45)
文摘Objectives: To evaluate the effects of the Chinese medicine (CM) five-element music on quality of life for senior and non-senior advanced cancer patients. Methods: With a randomized controlled trial, 170 advanced cancer patients were randomly assigned to three groups: the CM five-element music group (68 patients), the Western music therapy group (68 cases), and the no music therapy group (34 cases). All patients of 70 years old or older were considered seniors and the remaining patients younger than 70 years were considered non- seniors. Patients in the CM five-element music group listened to CM five-element music, the patients in the Western music group listened to Western music, and the patients in the no music group did not listen to music. A course of treatment was 3 weeks, with 30 rain each day, 5 days a week. The Hospice Quality of Life Index- Revised (HQOLI-R) and Karnofsky performance score (KPS) were measured in the three groups before and after treatment. The symptom diary score was measured in the three groups every 3 days, 7 times in total. Results: CM five-element music group showed a significant difference of HQOLI-R, KPS and symptom diary score with other groups (all P〈0.01). There were significant differences of HQOLI-R, symptom diary score, and KPS after treatment in CM five-element music group and other groups in the non-senior subgroup (P〈0.05). Additionally, there were significant differences in HQOLI-R and KPS after treatment among the three groups in the senior subgroup (P〈0.05). Conclusions: CM five-element music therapy could improve the quality of life and KPS for senior and non senior advanced cancer patients, and it could improve subjective symptoms for non-senior advanced cancer patients.
基金Supported by the National Natural Science Foundation of China(No.30701105)Beijing Municipal Educational Fund[(2007) No.20]
文摘Objective: To investigate the effects and mechanisms of Gong-tone music on the immunological function in rats with the Chinese medicine syndrome of Liver (Gan)-qi stagnation and Spleen (Pi)-qi deficiency (LSSD). Methods: Twenty five male Wistar rats of SPF grade were randomly divided into 5 groups: normal group, model group, Xiaoyao Powder (逍遥散) group, Gong-tone group and combined group (the combination of Gong-tone and Xiaoyao Powder), with 5 rats in each group. The rat model for the Chinese medicine syndrome of LSSD was induced by chronic bandage and irregular diet. The course of treatment was 21 days. After the treatment, the levels of serum gastrin and IgG were detected by enzyme-linked immunoabsorbent assay (ELISA). Phagocytosis of macrophages was detected by the neutral red uptake assay and T cell proliferation was investigated by 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) assay. Results: The serum gastrin, macrophage phagocytosis, IgG level and proliferation ability of T cells in the model group were significantly decreased compared with those in the normal group (P〈0.05). Compared with those in the model group, the serum levels of gastrin, macrophage phagocytosis, IgG level and proliferation ability of T cells in Gong-tone, Xiaoyao Powder, and combined groups were significantly increased (P〈0.05). The combined group was superior to either Gong-tone group or Xiaoyao Powder group. Conclusion: Gong-tone music may upregulate the immunological function and play a role in adjuvant therapy in the Chinese syndrome of LSSD.
基金Supported by the Assistance Project for the Developing Country Funded by the Ministry of Science and Technology of China (No.KY201302010)the National Major Foundational Research Development Project (973 project) (No.2011CB505404)+2 种基金the Beijing University of Chinese Medicine Innovative Group (No.2011-CXTD-05)the National Scienceand Technology Project in'12th Five Year Plan'Funded by the Ministry of Science and Technology (No.2012BA125B05)the National Basic Research Program of China (No.81173381)
文摘OBJECTIVE: To explore the effects of five-element music therapy on elderly patients with seasonal affective disorder in a Chinese nursing home.METHODS: The patients(n=50) were recruited from a Shijingshan district nursing home in Beijing,China. They were randomly assigned to two groups, a treatment group and a control group,with 25 participants in each group. The patients received music therapy for 1-2 h each week over an8-week period. The music therapy involved four phases: introduction, activities, listening to the Chinese five-element music, and a concluding phase.The participants in the control group did not listen to the five-element music. This study consisted of two parts:(a) a qualitative study that used focus groups to understand the feelings of the patients with seasonal affective disorder;(b) a quantitative study that involved administration of the self-rating depression scale(SDS) and Hamilton depression scale(HAMD) before and after treatment.RESULTS:(a) Qualitative analysis results: strength derived from the five-element group music therapy and emotional adjustment. The five-element group music therapy can reduce patients' psychological distress and let them feel inner peace and enhance their life satisfaction.(b) No significant difference in SDS and HAMD scores was found between the two groups(P>0.05) prior to treatment. After treatment,the mean SDS score of the control group was 49.9±18.8, while the treatment group's score was 40.2±18.1. The HAMD score of the control group was11.2±3.1, and the treatment group's score was 8.8±4.9. Following 8 weeks of music therapy, the SDS and HAMD scores of the treatment group were significantly lower than those for the control group(P<0.05).CONCLUSION: Five-element music therapy alleviated the symptoms of seasonal affective disorder in the elderly patients.
文摘Traditional Chinese medicine(TCM) plays an important role in the medical system used in health care and treatment of diseases.This article reviews the basic theory of TCM based on its formation and contributions.Two new personal points are proposed as follows:Six Zang(六脏) theory and deemphasization of the five-element theory.The basic theory of Chinese herbs is also discussed.
基金supported by Shanghai Key Laboratory of Health Identification and Assessment(Grant No.21DZ2271000).
文摘Background:Many original studies have shown that traditional Chinese five-element therapy(FEM-therapy)can effectively relieve anxiety,depression and quality of life.However,one published systematic review refuted this conclusion.To further clarify the efficacy of FEM therapy in relieving negative emotion among cancer patients and to assess the reliability of the evidence,this systematic review and meta-analysis was performed.Methods:We searched for randomized controlled trials(RCTs)comparing FEM-therapy versus standard care for cancer patients,six databases(CBM,PubMed,Cochrane Library,Web of Science,CNKI,and WanFang),two clinical trial registries and one gray literature database were searched from inception to October 31,2022.Two investigators independently screened literature,extracted data,and assessed risk of bias according to the Cochrane Handbook Version 6.1.0.The RevMan 5.3 software was used to perform the meta-analysis.Overall quality of evidence was rated using GRADE(Grading of Recommendations,Assessment,Development and Evaluation).Results:25 RCTs involving 1990 patients were finally included.Two of which had high risk bias,the remaining 23 were rated as unclear risk bias.Compared with other treatments,FEM-therapy combined with conventional nursing can significantly relieve anxiety(MD=-10.33,95%CI:[-13.77,-6.88],P<0.05;very low certainty)and depression(SMD=-1.10,95%CI:[-1.41,-0.79],P<0.05;very low certainty),and can significantly increase the quality of sleep(MD=-2.92,95%CI:[-4.89,-0.95],P<0.05;low certainty).Compared with acupuncture intervention,FEM-therapy combined with acupuncture can decreased the anxiety(SMD=-0.64,95%CI:[-0.98,-0.30],P<0.05;Moderate certainty)and depression(SMD=-0.68,95%CI:[-1.00,-0.32],P<0.05;Moderate certainty).Conclusion:Traditional Chinese FEM therapy combined with other treatments are effective in alleviating negative emotions among cancer patients.In order to better improve the quality of life of cancer patients and give more reliable advice,more trials of direct comparisons a
基金the National Natural Science Foundation of China(81373770)BUCM Research Development Fund Project(2016-ZXFZJJ-008).
文摘Objective:To investigate the neural mechanism of Gong tone matching to the five colors.Methods:The experiment was designed using event-related potential technique,following the S1 →S2 paradigm,and dividing into two arms according to the Gong tone being played in harmonics or open strings.For each arm,S1 was the playing of the Gong tone,followed by S2,where subjects,based on their first reaction,were required to make a yes/no judgement to whether the tone matches to a randomly-picked color out of the five colors.During this process,the event-related potentials were recorded.Results:Gong tone played in harmonics,most participants matched it with black and cyan;while in the open strings arm,most matched it with black.The average amplitudes of P300 at PZ,FZ,and CZ points were compared.For the Gong tone played in harmonics,there was a significant difference between those who matched it with black and those who did otherwise (P <.01).There was also a significant difference between those who matched it with cyan and those who did otherwise (P <.01).For the open strings arm,there was a significant difference between those who matched it with black and those who did otherwise (P <.01).Conclusion:Our comparison of the average amplitudes of P300 suggests a commonality in the neural mechanism underlying categorical thinking that is not fundamentally altered by playing style.However,behavioral theory suggests that playing style does have an influence on categorization.The Gong tone can be matched with any of the five colors,which accords with the thought of central Earth in the five-element theory.This provides evidence of the similarity within five elements correspondences existing alongside the indirect matching between five tones and five colors.