Skin depigmentation is a worrying practice that is gaining popularity, particularly among young girls. However, this practice poses health risks. It also reflects a negative view of black skin color. This was a cross-...Skin depigmentation is a worrying practice that is gaining popularity, particularly among young girls. However, this practice poses health risks. It also reflects a negative view of black skin color. This was a cross-sectional study carried out between April and May 2023 which involved 1039 female students from schools and universities in the Collines department selected by stratified sampling. Data was collected during a face-to-face interview using a questionnaire providing information on the demographic, socio-cultural, and economic characteristics of the girls. The depigmentation products used were identified as well as the complications caused by the use of these products. Statistical analysis made it possible to calculate the frequencies and logistic regression made it possible to identify the factors associated with depigmentation. The prevalence of depigmentation among the girls surveyed was 78.2%. The main products used were soaps based on mercurial derivative and hydroquinone (21.6%) and lotions based on hydroquinone and corticosteroids (75.7%). The factors associated with the practice of depigmentation were the ethnicity of the respondents (OR = 2.52;95% CI = [0.47 - 13.33], p = 0.001);the average monthly income of the parents (OR = 3.26;95% CI = [1.71 - 6.09], p = 0.003);the opinion of the respondents on depigmentation (OR = 2.48;95% CI = [0.84 - 7.3], p < 0.001) and the value given to light skin versus black skin (OR = 3.41;95% CI = [2.32 - 5.01], p < 0.001). In conclusion, the prevalence of depigmentation among the girls surveyed is high. Consequently, reinforced awareness measures and stricter control of bleaching products are imperative to address this high prevalence of the phenomenon.展开更多
Background: Tenofovir (TFV) is widely used to treat patients with hepatitis B virus (HBV) infection. But kidney abnormalities are the main concern using this drug. Few studies have described the renal impairment due t...Background: Tenofovir (TFV) is widely used to treat patients with hepatitis B virus (HBV) infection. But kidney abnormalities are the main concern using this drug. Few studies have described the renal impairment due to the TFV in chronic hepatitis B (CHB) in Sub-Saharan Africa. The objective was to evaluate factors associated with renal impairment observed in patients on TFV for CHB. Method: It was a hospital based cross sectional prospective study carried out from June 2023 to July 2023 in Yaoundé (Cameroon) and included any patient treated with TFV for CHB during at least a period of 6 months. For each participant, we collected in the medical report socio-demographic data, clinical data, baseline creatinine, treatment information (type of TFV which was Disoproxil Fumarate (TDF) or Alafenamide (TAF), duration). Then, we collected blood samples to measure serum creatinine and phosphate levels and urine dipstick analysis. Factors associated with renal impairment were assessed with the Odds Ratio. A p value of Results: A total of 60 participants were included. The median age was 44 years [36-55] and median duration of TFV therapy was 17.5 months [11.7-25.7]. The prevalence of reduced eGFR (Conclusion: Kidney function was impaired in some patients receiving TFV for CHB. It should be monitored, particularly after 36 months and for those receiving TDF prodrug.展开更多
Background: Women well-informed regarding breast cancer are often most conscious about their breast health and would therefore seek medical attention when detecting the initial symptoms. Objective: This study sought t...Background: Women well-informed regarding breast cancer are often most conscious about their breast health and would therefore seek medical attention when detecting the initial symptoms. Objective: This study sought to identify factors associated with a good level of knowledge regarding breast cancer among women in the commune of Parakou in 2021. Method: This was a prospective cross-sectional study with descriptive and analytical purposes, carried out from June 5 to August 5, 2022, among women residing in the first district of the commune of Parakou. A pre-designed questionnaire set up with the Kobotoolbox server was used for data collection through a cluster survey sampling technique. Pearson’s chi-square test was implemented to determine associations between variables. Result: A total of 630 women were included in this study. The prevalence of women well-informed about breast cancer was 21.75% (95% CI = [18.70 - 25.13]). Factors associated with good knowledge regarding breast cancer were age group (p-value < 0.001), school level (p-value < 0.001), occupation (p-value < 0.001), and regular attendance at a health facility (p-value Conclusion: Several women remain unaware of breast cancer in the commune of Parakou. A huge effort is still needed to increase the level of coverage of information regarding breast cancer and its prevention methods.展开更多
Introduction: Several microorganisms cause vaginal infections. Some of them include: Trichomonas vaginalis, Gardneralla vaginalis, Bacteriodes spp., Mobilincus and Candida albicans. In pregnancy, these infections are ...Introduction: Several microorganisms cause vaginal infections. Some of them include: Trichomonas vaginalis, Gardneralla vaginalis, Bacteriodes spp., Mobilincus and Candida albicans. In pregnancy, these infections are associated with considerable discomfort and adverse pregnancy outcome including preterm delivery, low birth weight, spontaneous abortions among others. Aims: Bacterial vaginosis, vulvovaginal trichomoniasis and candidiasis in pregnant women are associated with considerable discomfort and adverse pregnancy outcome (preterm delivery and low birth weight). We attempted to determine the prevalence of these conditions in Regional Hospital Bamenda. Methods: A total of 200 vaginal swabs were collected from pregnant women after the administration of a semi-structured questionnaire. The samples were analyzed using wet mount (Trichomonas vaginalis and Candida spp.), and the Gram stain (Gardnerella vaginalis and Candida spp.). Bivariate and multivariate analyses were used to investigate association between vaginal symptoms and their risk factors. Results: The overall prevalence of vaginal infections was 49.5%, with trichomoniasis, bacterial vaginosis, and candidiasis being 2% (4), 27% (54) and 32% (64), respectively. No formal education (AOR = 0.908;95% CI: -20.72 - 35.62;p = 0.001) and practice of douching (16.93: -0.201 - 29.692;p = 0.005) were found to be independent risk factors for trichomoniasis. Malodourous greenish vagina discharges (18.52;2.96 - 60.307;p = 0.005) were associated with trichomoniasis and bacterial vaginosis. White (6.566;17.785 - 21.836;p = 0.004) and yellowish (3.404;20.127 - 23.457;p = 0.004) vaginal discharges were independent risk factors for mycotic vagina infections. Multivariate analysis revealed that the only risk factor significantly associated to VVC in this study was the use of both water cistern and pit toilet (AOR = 3.684;95% CI: 0.388 - 2.649;p = 0.010). Conclusion: There was a high prevalence of vaginal infections. Early treatment will reduce the disease burden and avoid c展开更多
As in other countries of West Africa, Benin has a low rate of MCM utilization. The factors which lead to this low rate of use vary from one country to another. Purpose: The purpose of this work was to determine the fa...As in other countries of West Africa, Benin has a low rate of MCM utilization. The factors which lead to this low rate of use vary from one country to another. Purpose: The purpose of this work was to determine the factors associated with the use of modern contraceptive method (MCM) by women of childbearing age (WCBA) in Parakou in 2017. Materials and Methods: It was a cross-sectional and descriptive study with an analytical purpose among WCBA selected in households of the municipality of Parakou after a 2-degree cluster survey. Results: The WCBA’s average age was 29 ± 5.6 years old with extremes of 15 and 46 years. The modern contraceptive prevalence was 14.74%. Among WCBA, 57.14% had an average level of knowledge. The media were the main source of information (75.84%). Among them 34.39% never discussed the matter with their spouse;the latter were not in favor of contraception. The educational level, the perception of woman, the spouse’s favorable opinion, the discussion with the spouse, the level of knowledge of MCM and the knowledge of the existence of FP service were significantly associated with the use of MCM with p = 0.0000 after multivariate analysis. Conclusion: The level of MCM use still remains low. Any effort to increase the modern contraceptive prevalence should take into account its associated factors in order to optimize the use of MCM in the municipality of Parakou in 2017.展开更多
<strong>Introduction</strong><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><strong>:</strong...<strong>Introduction</strong><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><strong>:</strong> Maternal mortality is a robust indicator of human development. Most of it occurs in developing countries.</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><b><span style="font-family:Tahoma;">Objectives</span></b></span></span><span><span><span style="font-family:""><span style="font-family:Tahoma;">: This study aims to determine the factors associated with maternal mortality in </span><span style="font-family:Tahoma;">Gynecology</span><span style="font-family:Tahoma;"> and Obstetrics Department of Borgou Departmental University Hospital Center (CHUD-B).</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><b><span style="font-family:Tahoma;">Study method</span></b></span></span><span><span><span style="font-family:""><span style="font-family:Tahoma;">: Our study took place at Gynecology and Obstetrics Department in Borgou Departmental University Hospital Center. This was a descriptive and analytical case-control study, covering a period of 7 years from January 1, </span><span style="font-family:Tahoma;">2012</span><span style="font-family:Tahoma;"> to December 31, 2018.</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><b><span style="font-family:Tahoma;">Results</span></b></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><span style="font-family:Tahoma;">: Two hundred and twelve patients have been recruited consisting of 106 deceased women and 106 controls. The intra-hospital mortality ratio was 1100 deaths per 100,000 live births (LB). The mean age of deceased women was 27.06 ± 6.45 years with the extremes of 15 and 45 years展开更多
<strong>Background:</strong> Over the last century, stress as an interdisciplinary concept has become an area of great interest and has been researched extensively. Although the earliest studies on stress ...<strong>Background:</strong> Over the last century, stress as an interdisciplinary concept has become an area of great interest and has been researched extensively. Although the earliest studies on stress were mostly physiological, psychological models of stress have been developed and established a link between stressors and illness in his model of general adaptation syndrome.<strong> Objective:</strong> To investigate prevalence and factors associated with occupational stress among nurses working Asser region Hospital. The study included nurses at different age groups working at different departments with assessment of any sources of stress. <strong>Methodology: </strong>A descriptive cross-sectional study was conducted targeting nurses in the main hospitals in the Asser region, Southern Saudi Arabia. A total of the study samples of 217 nurses were required to estimate the expected average stress rate among nurses. A self-administered pre-structured questionnaire used for data collection. <strong>Results: </strong>Nurses’ ages ranged 21 to 55 years old with mean age of 30.9 ± 11.7 years old. Majority of the nurses were females 175 (80.6%). The highest mean score (more stress) was reported by nurses in relation to the following stress factors;working very hard (4.3 ± 0.9), followed by being under pressure to work long hours (4.2 ± 0.9), the opportunity given to do something is not real and enough (4.2 ± 1.0). The findings showed a significant relationship between nurses’ stress level, their personal and work-related characteristics (P = 0.001). <strong>Recommendations:</strong> Interventional programs to detect and alleviate sources and effects of occupational stress should be developed including more training regarding coping strategies, nurses’ support, and better work condition.展开更多
Background: For countries with limited resources such as the Democratic Republic of the Congo (DRC), the diagnosis of Multidrug-resistant tuberculosis (MDR-TB) is still insufficient. The MDR-TB identification is done ...Background: For countries with limited resources such as the Democratic Republic of the Congo (DRC), the diagnosis of Multidrug-resistant tuberculosis (MDR-TB) is still insufficient. The MDR-TB identification is done primarily among at-risk groups. The knowledge of the true extent of the MDR-TB remains a major challenge. This study tries to determine the proportion of MDR-TB in each group of presumptive MDR-TB patients and to identify some associated factors. Methods: This is an analysis of the DRC surveillance between 2007 and 2016. The proportions were expressed in Percentage. The logistic regression permits to identify the associated factors with the RR-/MDR-TB with adjusted Odds-ratio and 95% CI. Significance defined as p ≤ 0.05. Results: Overall, 83% (5407/6512) of the MDR-TB presumptive cases had each a TB test. 86.5% (4676/5407) had each a culture and drug sensitive testing (DST) on solid medium, and 24.3% (1312/5407) had performed an Xpert MTB/RIF test. The proportion of those with at least one first-line drug resistance was 59.3% [95% CI 57.2 - 61.4] among which 50.1%, [95% CI 47.9 - 52.3] for the isoniazid, 45.6% [95% CI 43.4 - 47.8] for the rifampicin, 49.9% [95% CI 47.8 - 52.1] for ethambutol and 35.8% [95% CI 33.7 - 37.9] for streptomycin. The confirmation of MDR-TB was 42.8% [95% CI 38.4 - 47.8]. Combining both tests, the proportion of RR-/MDR-TB was 49.6% [95% CI 47.9 - 51.4] for all presumptives. This proportion was 60.0% for failures, 40.7% for relapses and 34.7% for defaulters. Associated factors with the diagnosis of MDR-TB were: aged less than 35 years;prior treatment failure;defaulters;the delay between the collection of sputum and the test completion. Conclusion: The proportion of RR-/MDR-TB among the presumptives has been higher than those estimated generally. The National tuberculosis programme (NTP) should improve patient follow-up to reduce TB treatment failures and defaulting. Moreover, while increasing the use of molecular tests, they should reduce sample delivery times when they use展开更多
Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in chi...Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in children aged 1 month to 15 years. Methodology: This was a cross-sectional study which took place from January 1 to December 31, 2020 covering children aged 1 month to 15 years hospitalized at the Kalaban-Coro CSRéf. Data were entered into Excel and analyzed using SPSS version 20 software. Results: Five hundred children aged 1 months to 15 years were included. The age range 1 to 5 years (53.6%) and male sex (58.2%) were the most represented. Malaria (72.2%), acute respiratory infections (6.2%) and diarrhea/dehydration (3%) were the main morbidities. Mortality was estimated at 10.6%, and the two main causes of death were malaria (56.6%) and acute respiratory infections (7.54%). Univariate analysis revealed a statistically significant association between the dependent variable (death) and age (p Conclusion: This study confirms the high rate of infant and child morbidity and mortality in our health facilities. Strengthening human resources and intensifying behavior-change communication can help reverse the trend.展开更多
目的:探讨低分子肝素联合乙酰半胱氨酸(Acetylcysteine,AC)治疗特发性间质性肺炎(idipathic interstitial pneumonia,IIP)患者的疗效分析及其对涎液化糖链抗原-6(Krebs von den Lungen-6,KL-6)、过氧化物酶体增殖物激活受体γ(peroxisom...目的:探讨低分子肝素联合乙酰半胱氨酸(Acetylcysteine,AC)治疗特发性间质性肺炎(idipathic interstitial pneumonia,IIP)患者的疗效分析及其对涎液化糖链抗原-6(Krebs von den Lungen-6,KL-6)、过氧化物酶体增殖物激活受体γ(peroxisome proliferator-activated receptor gamma,PPARγ)水平及肺纤维化相关因子表达的影响。方法:选取我科2018年7月至2020年9月期间89例IIP患者作为研究对象,按照随机抽样法分成两组,对照组44例给予常规治疗,观察组45例给予低分子肝素联合AC治疗,12周后观察两组患者的临床疗效、肺功能、血清学指标、肺纤维化相关指标、不良反应。结果:观察组治疗后总有效率97.78%(44/45),高于对照组的79.55%(35/44),差异有统计学意义(χ^(2)=5.6996,P<0.05);两组患者治疗后各项肺功能指标均有改善,且观察组患者改善程度优于对照组(P<0.05);两组患者治疗后转化生长因子β1(transforming growth factor-β1,TGF-β1)、KL-6均降低,PPARγ均升高,且观察组患者变化程度大于对照组(P<0.05);两组患者治疗后结缔组织生长因子(Connective tissue growth factor,CTGF)、纤维连接蛋白(fibronectin,FN)水平均降低,且观察组患者降低程度更明显(P<0.05);观察组患者总不良反应发生率2.22%(1/45),低于对照组的18.18%(8/44)(χ^(2)=7.7689,P<0.05)。结论:低分子肝素联合AC治疗IIP患者的疗效确切,能有效改善患者的肺功能,抑制肺纤维化相关因子的表达,安全可靠,值得临床推广使用。展开更多
目的探讨输尿管软镜联合F4.8通道经皮肾镜在鹿角型结石患者中的应用效果及手术安全性、有效性及对尿源性炎症相关因子的影响。方法选择2019年5月—2020年5月鹿角型结石患者66例,采用随机数字表法分为两组,各33例。对照组采用输尿管软镜...目的探讨输尿管软镜联合F4.8通道经皮肾镜在鹿角型结石患者中的应用效果及手术安全性、有效性及对尿源性炎症相关因子的影响。方法选择2019年5月—2020年5月鹿角型结石患者66例,采用随机数字表法分为两组,各33例。对照组采用输尿管软镜治疗,观察组在对照组基础上联合F4.8通道经皮肾镜治疗,比较两组手术效果、视觉模拟疼痛(VAS)评分、一期结石清除率、并发症发生率及尿源性炎症相关因子。结果两组围术期出血量、住院费用、住院天数、术前及手术7 d VAS评分无统计意义(P>0.05);观察组手术时间长于对照组(P<0.05);两组感染、发热、术中出血、周围脏器损伤发生率无统计学意义(P>0.05);观察组一期结石清除率高于对照组;观察组术后7d尿源性炎症相关因子C反应蛋白(CRP)、降钙素原(PCT)、白介素(IL-6)低于对照组(P<0.05)。结论输尿管软镜联合F4.8通道经皮肾镜用于鹿角型结石患者中手术创伤较小,能减轻患者疼痛,提高结石清除率,能改善尿源性炎症相关因子水平,未增加并发症发生率,值得推广应用。展开更多
文摘Skin depigmentation is a worrying practice that is gaining popularity, particularly among young girls. However, this practice poses health risks. It also reflects a negative view of black skin color. This was a cross-sectional study carried out between April and May 2023 which involved 1039 female students from schools and universities in the Collines department selected by stratified sampling. Data was collected during a face-to-face interview using a questionnaire providing information on the demographic, socio-cultural, and economic characteristics of the girls. The depigmentation products used were identified as well as the complications caused by the use of these products. Statistical analysis made it possible to calculate the frequencies and logistic regression made it possible to identify the factors associated with depigmentation. The prevalence of depigmentation among the girls surveyed was 78.2%. The main products used were soaps based on mercurial derivative and hydroquinone (21.6%) and lotions based on hydroquinone and corticosteroids (75.7%). The factors associated with the practice of depigmentation were the ethnicity of the respondents (OR = 2.52;95% CI = [0.47 - 13.33], p = 0.001);the average monthly income of the parents (OR = 3.26;95% CI = [1.71 - 6.09], p = 0.003);the opinion of the respondents on depigmentation (OR = 2.48;95% CI = [0.84 - 7.3], p < 0.001) and the value given to light skin versus black skin (OR = 3.41;95% CI = [2.32 - 5.01], p < 0.001). In conclusion, the prevalence of depigmentation among the girls surveyed is high. Consequently, reinforced awareness measures and stricter control of bleaching products are imperative to address this high prevalence of the phenomenon.
文摘Background: Tenofovir (TFV) is widely used to treat patients with hepatitis B virus (HBV) infection. But kidney abnormalities are the main concern using this drug. Few studies have described the renal impairment due to the TFV in chronic hepatitis B (CHB) in Sub-Saharan Africa. The objective was to evaluate factors associated with renal impairment observed in patients on TFV for CHB. Method: It was a hospital based cross sectional prospective study carried out from June 2023 to July 2023 in Yaoundé (Cameroon) and included any patient treated with TFV for CHB during at least a period of 6 months. For each participant, we collected in the medical report socio-demographic data, clinical data, baseline creatinine, treatment information (type of TFV which was Disoproxil Fumarate (TDF) or Alafenamide (TAF), duration). Then, we collected blood samples to measure serum creatinine and phosphate levels and urine dipstick analysis. Factors associated with renal impairment were assessed with the Odds Ratio. A p value of Results: A total of 60 participants were included. The median age was 44 years [36-55] and median duration of TFV therapy was 17.5 months [11.7-25.7]. The prevalence of reduced eGFR (Conclusion: Kidney function was impaired in some patients receiving TFV for CHB. It should be monitored, particularly after 36 months and for those receiving TDF prodrug.
文摘Background: Women well-informed regarding breast cancer are often most conscious about their breast health and would therefore seek medical attention when detecting the initial symptoms. Objective: This study sought to identify factors associated with a good level of knowledge regarding breast cancer among women in the commune of Parakou in 2021. Method: This was a prospective cross-sectional study with descriptive and analytical purposes, carried out from June 5 to August 5, 2022, among women residing in the first district of the commune of Parakou. A pre-designed questionnaire set up with the Kobotoolbox server was used for data collection through a cluster survey sampling technique. Pearson’s chi-square test was implemented to determine associations between variables. Result: A total of 630 women were included in this study. The prevalence of women well-informed about breast cancer was 21.75% (95% CI = [18.70 - 25.13]). Factors associated with good knowledge regarding breast cancer were age group (p-value < 0.001), school level (p-value < 0.001), occupation (p-value < 0.001), and regular attendance at a health facility (p-value Conclusion: Several women remain unaware of breast cancer in the commune of Parakou. A huge effort is still needed to increase the level of coverage of information regarding breast cancer and its prevention methods.
文摘Introduction: Several microorganisms cause vaginal infections. Some of them include: Trichomonas vaginalis, Gardneralla vaginalis, Bacteriodes spp., Mobilincus and Candida albicans. In pregnancy, these infections are associated with considerable discomfort and adverse pregnancy outcome including preterm delivery, low birth weight, spontaneous abortions among others. Aims: Bacterial vaginosis, vulvovaginal trichomoniasis and candidiasis in pregnant women are associated with considerable discomfort and adverse pregnancy outcome (preterm delivery and low birth weight). We attempted to determine the prevalence of these conditions in Regional Hospital Bamenda. Methods: A total of 200 vaginal swabs were collected from pregnant women after the administration of a semi-structured questionnaire. The samples were analyzed using wet mount (Trichomonas vaginalis and Candida spp.), and the Gram stain (Gardnerella vaginalis and Candida spp.). Bivariate and multivariate analyses were used to investigate association between vaginal symptoms and their risk factors. Results: The overall prevalence of vaginal infections was 49.5%, with trichomoniasis, bacterial vaginosis, and candidiasis being 2% (4), 27% (54) and 32% (64), respectively. No formal education (AOR = 0.908;95% CI: -20.72 - 35.62;p = 0.001) and practice of douching (16.93: -0.201 - 29.692;p = 0.005) were found to be independent risk factors for trichomoniasis. Malodourous greenish vagina discharges (18.52;2.96 - 60.307;p = 0.005) were associated with trichomoniasis and bacterial vaginosis. White (6.566;17.785 - 21.836;p = 0.004) and yellowish (3.404;20.127 - 23.457;p = 0.004) vaginal discharges were independent risk factors for mycotic vagina infections. Multivariate analysis revealed that the only risk factor significantly associated to VVC in this study was the use of both water cistern and pit toilet (AOR = 3.684;95% CI: 0.388 - 2.649;p = 0.010). Conclusion: There was a high prevalence of vaginal infections. Early treatment will reduce the disease burden and avoid c
文摘As in other countries of West Africa, Benin has a low rate of MCM utilization. The factors which lead to this low rate of use vary from one country to another. Purpose: The purpose of this work was to determine the factors associated with the use of modern contraceptive method (MCM) by women of childbearing age (WCBA) in Parakou in 2017. Materials and Methods: It was a cross-sectional and descriptive study with an analytical purpose among WCBA selected in households of the municipality of Parakou after a 2-degree cluster survey. Results: The WCBA’s average age was 29 ± 5.6 years old with extremes of 15 and 46 years. The modern contraceptive prevalence was 14.74%. Among WCBA, 57.14% had an average level of knowledge. The media were the main source of information (75.84%). Among them 34.39% never discussed the matter with their spouse;the latter were not in favor of contraception. The educational level, the perception of woman, the spouse’s favorable opinion, the discussion with the spouse, the level of knowledge of MCM and the knowledge of the existence of FP service were significantly associated with the use of MCM with p = 0.0000 after multivariate analysis. Conclusion: The level of MCM use still remains low. Any effort to increase the modern contraceptive prevalence should take into account its associated factors in order to optimize the use of MCM in the municipality of Parakou in 2017.
文摘<strong>Introduction</strong><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><strong>:</strong> Maternal mortality is a robust indicator of human development. Most of it occurs in developing countries.</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><b><span style="font-family:Tahoma;">Objectives</span></b></span></span><span><span><span style="font-family:""><span style="font-family:Tahoma;">: This study aims to determine the factors associated with maternal mortality in </span><span style="font-family:Tahoma;">Gynecology</span><span style="font-family:Tahoma;"> and Obstetrics Department of Borgou Departmental University Hospital Center (CHUD-B).</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><b><span style="font-family:Tahoma;">Study method</span></b></span></span><span><span><span style="font-family:""><span style="font-family:Tahoma;">: Our study took place at Gynecology and Obstetrics Department in Borgou Departmental University Hospital Center. This was a descriptive and analytical case-control study, covering a period of 7 years from January 1, </span><span style="font-family:Tahoma;">2012</span><span style="font-family:Tahoma;"> to December 31, 2018.</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><b><span style="font-family:Tahoma;">Results</span></b></span></span><span style="font-family:Tahoma;"><span style="font-family:Tahoma;"><span style="font-family:Tahoma;">: Two hundred and twelve patients have been recruited consisting of 106 deceased women and 106 controls. The intra-hospital mortality ratio was 1100 deaths per 100,000 live births (LB). The mean age of deceased women was 27.06 ± 6.45 years with the extremes of 15 and 45 years
文摘<strong>Background:</strong> Over the last century, stress as an interdisciplinary concept has become an area of great interest and has been researched extensively. Although the earliest studies on stress were mostly physiological, psychological models of stress have been developed and established a link between stressors and illness in his model of general adaptation syndrome.<strong> Objective:</strong> To investigate prevalence and factors associated with occupational stress among nurses working Asser region Hospital. The study included nurses at different age groups working at different departments with assessment of any sources of stress. <strong>Methodology: </strong>A descriptive cross-sectional study was conducted targeting nurses in the main hospitals in the Asser region, Southern Saudi Arabia. A total of the study samples of 217 nurses were required to estimate the expected average stress rate among nurses. A self-administered pre-structured questionnaire used for data collection. <strong>Results: </strong>Nurses’ ages ranged 21 to 55 years old with mean age of 30.9 ± 11.7 years old. Majority of the nurses were females 175 (80.6%). The highest mean score (more stress) was reported by nurses in relation to the following stress factors;working very hard (4.3 ± 0.9), followed by being under pressure to work long hours (4.2 ± 0.9), the opportunity given to do something is not real and enough (4.2 ± 1.0). The findings showed a significant relationship between nurses’ stress level, their personal and work-related characteristics (P = 0.001). <strong>Recommendations:</strong> Interventional programs to detect and alleviate sources and effects of occupational stress should be developed including more training regarding coping strategies, nurses’ support, and better work condition.
文摘Background: For countries with limited resources such as the Democratic Republic of the Congo (DRC), the diagnosis of Multidrug-resistant tuberculosis (MDR-TB) is still insufficient. The MDR-TB identification is done primarily among at-risk groups. The knowledge of the true extent of the MDR-TB remains a major challenge. This study tries to determine the proportion of MDR-TB in each group of presumptive MDR-TB patients and to identify some associated factors. Methods: This is an analysis of the DRC surveillance between 2007 and 2016. The proportions were expressed in Percentage. The logistic regression permits to identify the associated factors with the RR-/MDR-TB with adjusted Odds-ratio and 95% CI. Significance defined as p ≤ 0.05. Results: Overall, 83% (5407/6512) of the MDR-TB presumptive cases had each a TB test. 86.5% (4676/5407) had each a culture and drug sensitive testing (DST) on solid medium, and 24.3% (1312/5407) had performed an Xpert MTB/RIF test. The proportion of those with at least one first-line drug resistance was 59.3% [95% CI 57.2 - 61.4] among which 50.1%, [95% CI 47.9 - 52.3] for the isoniazid, 45.6% [95% CI 43.4 - 47.8] for the rifampicin, 49.9% [95% CI 47.8 - 52.1] for ethambutol and 35.8% [95% CI 33.7 - 37.9] for streptomycin. The confirmation of MDR-TB was 42.8% [95% CI 38.4 - 47.8]. Combining both tests, the proportion of RR-/MDR-TB was 49.6% [95% CI 47.9 - 51.4] for all presumptives. This proportion was 60.0% for failures, 40.7% for relapses and 34.7% for defaulters. Associated factors with the diagnosis of MDR-TB were: aged less than 35 years;prior treatment failure;defaulters;the delay between the collection of sputum and the test completion. Conclusion: The proportion of RR-/MDR-TB among the presumptives has been higher than those estimated generally. The National tuberculosis programme (NTP) should improve patient follow-up to reduce TB treatment failures and defaulting. Moreover, while increasing the use of molecular tests, they should reduce sample delivery times when they use
文摘Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in children aged 1 month to 15 years. Methodology: This was a cross-sectional study which took place from January 1 to December 31, 2020 covering children aged 1 month to 15 years hospitalized at the Kalaban-Coro CSRéf. Data were entered into Excel and analyzed using SPSS version 20 software. Results: Five hundred children aged 1 months to 15 years were included. The age range 1 to 5 years (53.6%) and male sex (58.2%) were the most represented. Malaria (72.2%), acute respiratory infections (6.2%) and diarrhea/dehydration (3%) were the main morbidities. Mortality was estimated at 10.6%, and the two main causes of death were malaria (56.6%) and acute respiratory infections (7.54%). Univariate analysis revealed a statistically significant association between the dependent variable (death) and age (p Conclusion: This study confirms the high rate of infant and child morbidity and mortality in our health facilities. Strengthening human resources and intensifying behavior-change communication can help reverse the trend.
文摘目的探讨输尿管软镜联合F4.8通道经皮肾镜在鹿角型结石患者中的应用效果及手术安全性、有效性及对尿源性炎症相关因子的影响。方法选择2019年5月—2020年5月鹿角型结石患者66例,采用随机数字表法分为两组,各33例。对照组采用输尿管软镜治疗,观察组在对照组基础上联合F4.8通道经皮肾镜治疗,比较两组手术效果、视觉模拟疼痛(VAS)评分、一期结石清除率、并发症发生率及尿源性炎症相关因子。结果两组围术期出血量、住院费用、住院天数、术前及手术7 d VAS评分无统计意义(P>0.05);观察组手术时间长于对照组(P<0.05);两组感染、发热、术中出血、周围脏器损伤发生率无统计学意义(P>0.05);观察组一期结石清除率高于对照组;观察组术后7d尿源性炎症相关因子C反应蛋白(CRP)、降钙素原(PCT)、白介素(IL-6)低于对照组(P<0.05)。结论输尿管软镜联合F4.8通道经皮肾镜用于鹿角型结石患者中手术创伤较小,能减轻患者疼痛,提高结石清除率,能改善尿源性炎症相关因子水平,未增加并发症发生率,值得推广应用。
