For the first time, Pd supported on natural palygorskite was developed for amine formylation with CO2 and H2. Both secondary and primary amines with diverse structures could be converted into the desired formamides at...For the first time, Pd supported on natural palygorskite was developed for amine formylation with CO2 and H2. Both secondary and primary amines with diverse structures could be converted into the desired formamides at < 100 °C, and good to excellent yields were obtained.展开更多
Dimethylbenzimidazolium iodide as an available convenient agent has been reacted with a Grignard reagent CH 3(CH 2) 5MgBr to give heptanal. The method need not neccessarily to isolate benzimidazolidine. The reaction m...Dimethylbenzimidazolium iodide as an available convenient agent has been reacted with a Grignard reagent CH 3(CH 2) 5MgBr to give heptanal. The method need not neccessarily to isolate benzimidazolidine. The reaction mechanism is discussed.展开更多
Synthetic method of asymmetry polyarylamino\|benzaldehydes by the selective formylation of polyarylamines in Vilsmeier\|Haack reaction was studied. Five polyarylamino\|benzaldehydes, \{4\|\%N\|\%methylphenylamino\}\|b...Synthetic method of asymmetry polyarylamino\|benzaldehydes by the selective formylation of polyarylamines in Vilsmeier\|Haack reaction was studied. Five polyarylamino\|benzaldehydes, \{4\|\%N\|\%methylphenylamino\}\|benzaldehyde, 4\|\%N\|\%（\%n\%\|butyl）\|phenylamino\|benzaldehyde, 4\|diphenylamino\|benzaldehyde, 4\|\%N\|\%phenyl\|diphenylamino\|benzaldehyde, 4\|\%N\|\%phenyl\|（4′\|diphenylamino）diphenylamino\|benzaldehyde were synthesized by the selective formylation of the polyarylamines with POCl\-3 and DMF in the yields of 67%\92%. The structures of these aldehydes were characterized by MS, \{\}\+1H NMR, IR. The studied results showed that the yields and selectivity of asymmetry polyarylamino\|benzaldehydes were found to relate with the reaction time, structures of polyarylamines and the molar ratio of the reactants.展开更多
Trimethylsilylation of alcohols was achieved using 1,1,1,3,3,3-hexamethyldisilazane（HMDS） as silylating agent,in the presence of polyvinylpolypyrrolidonium tribromide in acetonitrile at room temperature.Also a varie...Trimethylsilylation of alcohols was achieved using 1,1,1,3,3,3-hexamethyldisilazane（HMDS） as silylating agent,in the presence of polyvinylpolypyrrolidonium tribromide in acetonitrile at room temperature.Also a variety of alcohols were converted into alkyl formates by ethyl formate and a catalytic amount of polyvinylpolypyrrolidonium tribromide under solvent free conditions at room temperature.展开更多
A highly efficient and selective bimetallic Pd0.88Co0.12 nanoparticle catalyst was developed for the direct N-formylation of amines by carbon monoxide. This catalyst is compatible with a wide range of substrates, affo...A highly efficient and selective bimetallic Pd0.88Co0.12 nanoparticle catalyst was developed for the direct N-formylation of amines by carbon monoxide. This catalyst is compatible with a wide range of substrates, affording various synthetically useful formamides under practical and mild reaction conditions.展开更多
2-（Sulfooxy）propane-1,2,3-tricarboxylic acid（supported on silica gel） has been introduced as novel and green catalyst for the formylation of alcohols and amines with ethyl formate,as mild formylation agent,under n...2-（Sulfooxy）propane-1,2,3-tricarboxylic acid（supported on silica gel） has been introduced as novel and green catalyst for the formylation of alcohols and amines with ethyl formate,as mild formylation agent,under neat conditions at room temperature.展开更多
Different alcohols were formylated by formic acid under solvent-free conditions in the presence of iodine as the catalyst with good-to-high yields at room temperature.I2 generated in situ from Fe(NO3)3·9H2O/NaI a...Different alcohols were formylated by formic acid under solvent-free conditions in the presence of iodine as the catalyst with good-to-high yields at room temperature.I2 generated in situ from Fe(NO3)3·9H2O/NaI also catalyzed the formylation of the alcohols under solvent-free conditions.This gives a green and efficient reaction at room temperature,in which the use of toxic and corrosive molecular I2 is avoided.展开更多
The Vilsmeir formylation of 6 dialkylferrocenes has been found to produce nearly exclusively β isomers.The effect of temperature and the substrates etc.on the reaction was investigated.The structures of these compoun...The Vilsmeir formylation of 6 dialkylferrocenes has been found to produce nearly exclusively β isomers.The effect of temperature and the substrates etc.on the reaction was investigated.The structures of these compounds were characterized by elementary analysis、IR and 1HNMR.展开更多
基金supported by the National Natural Science Foundation of China(91745106,21633013)the Major Projects of the National Natural Science Foundation of Gansu,China(18JR4RA001)+1 种基金the Youth Innovation Promotion Association CAS(2019409)Fujian Institute of Innovation,CAS and Key Research Program of Frontier Sciences of CAS(QYZDJ-SSW-SLH051)~~
文摘For the first time, Pd supported on natural palygorskite was developed for amine formylation with CO2 and H2. Both secondary and primary amines with diverse structures could be converted into the desired formamides at < 100 °C, and good to excellent yields were obtained.
文摘Dimethylbenzimidazolium iodide as an available convenient agent has been reacted with a Grignard reagent CH 3(CH 2) 5MgBr to give heptanal. The method need not neccessarily to isolate benzimidazolidine. The reaction mechanism is discussed.
文摘Synthetic method of asymmetry polyarylamino\|benzaldehydes by the selective formylation of polyarylamines in Vilsmeier\|Haack reaction was studied. Five polyarylamino\|benzaldehydes, \{4\|\%N\|\%methylphenylamino\}\|benzaldehyde, 4\|\%N\|\%（\%n\%\|butyl）\|phenylamino\|benzaldehyde, 4\|diphenylamino\|benzaldehyde, 4\|\%N\|\%phenyl\|diphenylamino\|benzaldehyde, 4\|\%N\|\%phenyl\|（4′\|diphenylamino）diphenylamino\|benzaldehyde were synthesized by the selective formylation of the polyarylamines with POCl\-3 and DMF in the yields of 67%\92%. The structures of these aldehydes were characterized by MS, \{\}\+1H NMR, IR. The studied results showed that the yields and selectivity of asymmetry polyarylamino\|benzaldehydes were found to relate with the reaction time, structures of polyarylamines and the molar ratio of the reactants.
文摘Trimethylsilylation of alcohols was achieved using 1,1,1,3,3,3-hexamethyldisilazane（HMDS） as silylating agent,in the presence of polyvinylpolypyrrolidonium tribromide in acetonitrile at room temperature.Also a variety of alcohols were converted into alkyl formates by ethyl formate and a catalytic amount of polyvinylpolypyrrolidonium tribromide under solvent free conditions at room temperature.
基金We acknowledge financial support from the China Ministry of Science and Technology （No. 2016YFA0202801）, National Natural Science Foundation of China （No. 21371107）, Tsinghua-Peking Joint Centers for Life Sciences and CAMS Initiative for Innovative Medicine （No. 2016-I2M-3-014）.
文摘A highly efficient and selective bimetallic Pd0.88Co0.12 nanoparticle catalyst was developed for the direct N-formylation of amines by carbon monoxide. This catalyst is compatible with a wide range of substrates, affording various synthetically useful formamides under practical and mild reaction conditions.
基金Financial support for this work by the Ilam University,Ilam,Iran is gratefully acknowledged
文摘2-（Sulfooxy）propane-1,2,3-tricarboxylic acid（supported on silica gel） has been introduced as novel and green catalyst for the formylation of alcohols and amines with ethyl formate,as mild formylation agent,under neat conditions at room temperature.
基金Supported by Bu-Ali Sina University and University of Kurdistan Research Councils
文摘Different alcohols were formylated by formic acid under solvent-free conditions in the presence of iodine as the catalyst with good-to-high yields at room temperature.I2 generated in situ from Fe(NO3)3·9H2O/NaI also catalyzed the formylation of the alcohols under solvent-free conditions.This gives a green and efficient reaction at room temperature,in which the use of toxic and corrosive molecular I2 is avoided.
文摘The Vilsmeir formylation of 6 dialkylferrocenes has been found to produce nearly exclusively β isomers.The effect of temperature and the substrates etc.on the reaction was investigated.The structures of these compounds were characterized by elementary analysis、IR and 1HNMR.
