In thefield of diagnosis of medical images the challenge lies in tracking and identifying the defective cells and the extent of the defective region within the complex structure of a brain cavity.Locating the defective...In thefield of diagnosis of medical images the challenge lies in tracking and identifying the defective cells and the extent of the defective region within the complex structure of a brain cavity.Locating the defective cells precisely during the diagnosis phase helps tofight the greatest exterminator of mankind.Early detec-tion of these defective cells requires an accurate computer-aided diagnostic system(CAD)that supports early treatment and promotes survival rates of patients.An ear-lier version of CAD systems relies greatly on the expertise of radiologist and it con-sumed more time to identify the defective region.The manuscript takes the efficacy of coalescing features like intensity,shape,and texture of the magnetic resonance image(MRI).In the Enhanced Feature Fusion Segmentation based classification method(EEFS)the image is enhanced and segmented to extract the prominent fea-tures.To bring out the desired effect the EEFS method uses Enhanced Local Binary Pattern(EnLBP),Partisan Gray Level Co-occurrence Matrix Histogram of Oriented Gradients(PGLCMHOG),and iGrab cut method to segment image.These prominent features along with deep features are coalesced to provide a single-dimensional fea-ture vector that is effectively used for prediction.The coalesced vector is used with the existing classifiers to compare the results of these classifiers with that of the gen-erated vector.The generated vector provides promising results with commendably less computatio nal time for pre-processing and classification of MR medical images.展开更多
An improved rotating microchannel(IRM) separator was further explored in the intensification for demulsification and separation process. Oil-in-water(O/W) emulsion system of 2-ethylhexyl phosphoric acid-2-ethylhexyl e...An improved rotating microchannel(IRM) separator was further explored in the intensification for demulsification and separation process. Oil-in-water(O/W) emulsion system of 2-ethylhexyl phosphoric acid-2-ethylhexyl ester(P507)–water without emulsifier was employed to evaluate the performance of the new equipment. In this experiment, the influence on demulsification separation process was explored by changing the geometrical structure and channel height of the microchannel and combining the liquid–liquid two-phase flow pattern, and the correlation general graph between demulsification efficiency and dimensionless parameters was established. The total demulsification effect of the IRM and the separation capacity of the clear organic phase recovered from demulsification are significantly improved. In addition, the liquid–liquid two-phase flow pattern of the clear organic phase after demulsification and the remaining emulsion in the IRM are observed and recorded by high-speed photography. The separation ability of organic phase from the upper outlet can be significantly improved when the total demulsification rate of IRM is up to 90%. There are 3 types and 6 kinds of flow patterns observed. The results demonstrated that the suitable demulsification performance is obtained when the liquid–liquid two-phase inside the IRM is in a parallel pattern. Finally, the relation map between total demulsification efficiency and the universal flow is drawn, which provides a basis for the accurate control of the IRM device.展开更多
To make clear the precise hemodynamic mechanism underlying the anti-atherogenesis benefit of enhanced external couterpulsation(EECP) treatment, and to investigate the proper role of some important hemodynamic factors ...To make clear the precise hemodynamic mechanism underlying the anti-atherogenesis benefit of enhanced external couterpulsation(EECP) treatment, and to investigate the proper role of some important hemodynamic factors during the atherosclerotic progress, a comprehensive study combining long-term animal experiment and numerical solving was conducted in this paper. An experimentally induced hypercholesterolemic porcine model was developed and the chronic EECP intervention was subjected. Basic hemodynamic measurement was performed in vivo, as well as the arterial endothelial samples were extracted for physiological examination. Meanwhile, a numerical model was introduced to solve the complex hemodynamic factors such as WSS and OSI. The results show that EECP treatment resulted in significant increase of the instant levels of arterial WSS, blood pressure, and OSI. During EECP treatment, the instant OSI level of the common carotid arteries over cardiac cycles raised to a mean value of 8.58 ×10-2±2.13 ×10-2. Meanwhile, the chronic intervention of EECP treatment significantly reduced the atherosclerotic lesions in abdominal aortas and the endothelial cellular adherence. The present study suggests that the unique blood flow pattern induced by EECP treatment and the augmentation of WSS level in cardiac cycles may be the most important hemodynamic mechanism that contribute to its anti-atherogenesis effect. And as one of the indices that cause great concern in current hemodynamic study, OSI may not play a key role during the initiation of atherosclerosis.展开更多
目的探讨加速康复外科(enhanced recovery after surgery,ERAS)理念下多学科共管模式在急诊老年髋部骨折围手术期护理中的应用效果,以期提高老年髋部骨折的治疗效果。方法采用不同病例前-后对照研究方法,将2015年5月—2017年2月在本院...目的探讨加速康复外科(enhanced recovery after surgery,ERAS)理念下多学科共管模式在急诊老年髋部骨折围手术期护理中的应用效果,以期提高老年髋部骨折的治疗效果。方法采用不同病例前-后对照研究方法,将2015年5月—2017年2月在本院急诊住院手术的375例老年髋部骨折患者设为对照组,采用围手术期常规治疗护理;将2017年3月—2018年10月在本院急诊住院手术的401例老年髋部骨折患者设为试验组,采用ERAS理念下多学科共管模式治疗护理程式。比较两组患者入院至手术的时间,48h内手术的比例,术后并发症发生率,总住院时间和围手术期死亡率。结果两组患者入院至手术的时间,48h内手术的比例,术后并发症发生率,总住院时间和围手术期死亡率比较,均P<0.05,差异具有统计学意义,试验组患者入院到手术的时间短于对照组,48h内手术率高于对照组,术后并发症发生率与围手术期死亡率低于对照组。结论急诊老年髋部骨折患者采用ERAS理念下多学科共管模式治疗护理,可提高48h手术率,降低术后并发症发生率,缩短住院时间及降低围手术期死亡率。展开更多
目的观察分析小肝细胞性肝癌（ small hepatocellular carcinoma，sHCC）迟发性复发病灶超声造影影像学特征及临床意义。方法以初发性小肝癌（primary small hepatocellular carcinoma，PsHCC）52例68个病灶为对照组，2年内首发的复发...目的观察分析小肝细胞性肝癌（ small hepatocellular carcinoma，sHCC）迟发性复发病灶超声造影影像学特征及临床意义。方法以初发性小肝癌（primary small hepatocellular carcinoma，PsHCC）52例68个病灶为对照组，2年内首发的复发性小肝细胞性肝癌（recurrent small hepatocellular carcinoma，RsHCC） 293例367个病灶为RsHCC 1组（R1组），2年后首发的RsHCC 46例51个病灶为RsHCC 2组（R2组），分析比较三组间超声造影强化始增时间、达峰时间、开始消退时间、低增强开始时间及各时相灌注模式等血流动力学参数。
结果R2组与对照组及R1组比较，始增时间、达峰时间、开始消退时间及低增强开始时间的差异均有统计学意义（P〈0.05）；而上述参数指标在R1组与对照组间差异均无统计学意义（P〉0.05）。R2组分别与对照组及R1组比较，动脉期和延迟期时相差异均有统计学意义（P〈0.05），门脉期三组分布差异均无统计学意义（P〉0.05）; R1组与对照组各时相分布差异均无统计学意义（P〉0.05）。结论迟发性RsHCC超声造影灌注模式虽仍以快进快退为主，但也呈现出多样化趋势，对肝癌迟发性复发灶超声造影强化模式的研究，结合其他相关资料，有可能为临床提供一个简便、有一定参考价值的方法。展开更多
文摘In thefield of diagnosis of medical images the challenge lies in tracking and identifying the defective cells and the extent of the defective region within the complex structure of a brain cavity.Locating the defective cells precisely during the diagnosis phase helps tofight the greatest exterminator of mankind.Early detec-tion of these defective cells requires an accurate computer-aided diagnostic system(CAD)that supports early treatment and promotes survival rates of patients.An ear-lier version of CAD systems relies greatly on the expertise of radiologist and it con-sumed more time to identify the defective region.The manuscript takes the efficacy of coalescing features like intensity,shape,and texture of the magnetic resonance image(MRI).In the Enhanced Feature Fusion Segmentation based classification method(EEFS)the image is enhanced and segmented to extract the prominent fea-tures.To bring out the desired effect the EEFS method uses Enhanced Local Binary Pattern(EnLBP),Partisan Gray Level Co-occurrence Matrix Histogram of Oriented Gradients(PGLCMHOG),and iGrab cut method to segment image.These prominent features along with deep features are coalesced to provide a single-dimensional fea-ture vector that is effectively used for prediction.The coalesced vector is used with the existing classifiers to compare the results of these classifiers with that of the gen-erated vector.The generated vector provides promising results with commendably less computatio nal time for pre-processing and classification of MR medical images.
文摘An improved rotating microchannel(IRM) separator was further explored in the intensification for demulsification and separation process. Oil-in-water(O/W) emulsion system of 2-ethylhexyl phosphoric acid-2-ethylhexyl ester(P507)–water without emulsifier was employed to evaluate the performance of the new equipment. In this experiment, the influence on demulsification separation process was explored by changing the geometrical structure and channel height of the microchannel and combining the liquid–liquid two-phase flow pattern, and the correlation general graph between demulsification efficiency and dimensionless parameters was established. The total demulsification effect of the IRM and the separation capacity of the clear organic phase recovered from demulsification are significantly improved. In addition, the liquid–liquid two-phase flow pattern of the clear organic phase after demulsification and the remaining emulsion in the IRM are observed and recorded by high-speed photography. The separation ability of organic phase from the upper outlet can be significantly improved when the total demulsification rate of IRM is up to 90%. There are 3 types and 6 kinds of flow patterns observed. The results demonstrated that the suitable demulsification performance is obtained when the liquid–liquid two-phase inside the IRM is in a parallel pattern. Finally, the relation map between total demulsification efficiency and the universal flow is drawn, which provides a basis for the accurate control of the IRM device.
基金Key Clinical Project from the Ministry of Healthgrant number:25400+1 种基金National Natural Science Foundation of Chinagrant number:81170272
文摘To make clear the precise hemodynamic mechanism underlying the anti-atherogenesis benefit of enhanced external couterpulsation(EECP) treatment, and to investigate the proper role of some important hemodynamic factors during the atherosclerotic progress, a comprehensive study combining long-term animal experiment and numerical solving was conducted in this paper. An experimentally induced hypercholesterolemic porcine model was developed and the chronic EECP intervention was subjected. Basic hemodynamic measurement was performed in vivo, as well as the arterial endothelial samples were extracted for physiological examination. Meanwhile, a numerical model was introduced to solve the complex hemodynamic factors such as WSS and OSI. The results show that EECP treatment resulted in significant increase of the instant levels of arterial WSS, blood pressure, and OSI. During EECP treatment, the instant OSI level of the common carotid arteries over cardiac cycles raised to a mean value of 8.58 ×10-2±2.13 ×10-2. Meanwhile, the chronic intervention of EECP treatment significantly reduced the atherosclerotic lesions in abdominal aortas and the endothelial cellular adherence. The present study suggests that the unique blood flow pattern induced by EECP treatment and the augmentation of WSS level in cardiac cycles may be the most important hemodynamic mechanism that contribute to its anti-atherogenesis effect. And as one of the indices that cause great concern in current hemodynamic study, OSI may not play a key role during the initiation of atherosclerosis.
文摘目的探讨加速康复外科(enhanced recovery after surgery,ERAS)理念下多学科共管模式在急诊老年髋部骨折围手术期护理中的应用效果,以期提高老年髋部骨折的治疗效果。方法采用不同病例前-后对照研究方法,将2015年5月—2017年2月在本院急诊住院手术的375例老年髋部骨折患者设为对照组,采用围手术期常规治疗护理;将2017年3月—2018年10月在本院急诊住院手术的401例老年髋部骨折患者设为试验组,采用ERAS理念下多学科共管模式治疗护理程式。比较两组患者入院至手术的时间,48h内手术的比例,术后并发症发生率,总住院时间和围手术期死亡率。结果两组患者入院至手术的时间,48h内手术的比例,术后并发症发生率,总住院时间和围手术期死亡率比较,均P<0.05,差异具有统计学意义,试验组患者入院到手术的时间短于对照组,48h内手术率高于对照组,术后并发症发生率与围手术期死亡率低于对照组。结论急诊老年髋部骨折患者采用ERAS理念下多学科共管模式治疗护理,可提高48h手术率,降低术后并发症发生率,缩短住院时间及降低围手术期死亡率。
文摘针对高压隔膜泵机械结构复杂,单向阀故障特征信息分布在多尺度上,单一尺度难以全面提取特征的问题,提出了一种基于参数优化变分模态分解(Variational Mode Decomposition,VMD)和增强多尺度排列熵(Enhanced Multi-scale Permutation Entropy,EMPE)的单向阀故障诊断方法。对单向阀振动信号进行VMD分解,以包络熵最小原则对其进行参数优化,获得既定的若干本征模态函数(Intrinsic Mode Function,IMF)分量;计算IMF分量的增强多尺度排列熵,构建故障特征值向量;利用基于变量预测模型的模式识别(Variable Predictive Model Based Class Discriminate,VPMCD)方法对故障特征值向量进行训练和识别,进而实现单向阀的故障诊断。仿真信号和工程实验分析表明,该方法可以准确地识别单向阀的故障类型,具有一定的可靠性和工程应用价值。
