目的调查分析脑梗死患者临床流行病学特征,为脑梗死疾病预防和治疗工作提供依据。方法通过医院信息系统(Hospital Information System,HIS),按照脑梗死的国际疾病分类(International Classification of Diseases, ICD-10)(I63),采集2013...目的调查分析脑梗死患者临床流行病学特征,为脑梗死疾病预防和治疗工作提供依据。方法通过医院信息系统(Hospital Information System,HIS),按照脑梗死的国际疾病分类(International Classification of Diseases, ICD-10)(I63),采集2013—2017年江苏阜宁县中医院收治的主要诊断为脑梗死的首次住院患者病案首页信息,统计患者性别、年龄、疾病构成、入院时间、共病等情况。结果研究期间,累计出院脑梗死患者1 265人次,其中多发性脑梗死占比最高(45.77%)。男女性别比为1.60∶1,且性别间患者年龄构成存在差异(χ~2=19.765,P=0.001),60岁以上女性占比高于男性。第四季度脑梗死患者入院人数最多(27.11%)。脑梗死患者与高血压、高脂血症和糖尿病的共病率为64.11%,且女性共病率(69.75%)高于男性(60.59%),差异具有统计学意义(χ~2=10.920,P=0.001)。结论脑梗死住院患者呈现逐年增长趋势,且男性多于女性;脑梗死患者在出院诊断类别和入院时间分布均存在聚集性;脑梗死与高血压、高脂血症和糖尿病普遍具有共病现象。展开更多
AIM: To investigate the impact of enteral nutrition(EN) on the body composition and metabolism in patientswith Crohn's disease(CD). METHODS: Sixty-one patients diagnosed with CD were enrolled in this study. They w...AIM: To investigate the impact of enteral nutrition(EN) on the body composition and metabolism in patientswith Crohn's disease(CD). METHODS: Sixty-one patients diagnosed with CD were enrolled in this study. They were given only EN(enteral nutritional suspension, TPF, non-elemental diet) support for 4 wk, without any treatment with corticosteroids, immunosuppressive drugs, infliximab or by surgical operation. Body composition statistics such as weight, body mass index, skeletal muscle mass(SMM), fat mass, protein mass and inflammation indexes such as C-reactive protein(CRP), erythrocyte sedimentation rate(ESR) and CD activity index(CDAI) were recorded before and after EN support. RESULTS: The 61 patients were divided into three groups according to CDAI before and after EN support: A(active phase into remission via EN, n = 21), B(remained in active phase before and after EN, n = 19) and C(in remission before and after EN, n = 21). Patients in group A had a significant increase in SMM(22.11 ± 4.77 kg vs 23.23 ± 4.49 kg, P = 0.044), protein mass(8.01 ± 1.57 kg vs 8.44 ± 1.45 kg, P = 0.019) and decrease in resting energy expenditure(REE) per kilogram(27.42 ± 5.01 kcal/kg per day vs 22.62 ± 5.45 kcal/kg per day, P < 0.05). There was no significant difference between predicted and measured REE in active CD patients according to the HarrisBenedict equation. There was no linear correlation between the measured REE and CRP, ESR or CDAI in active CD patients. CONCLUSION: EN could decrease the hypermetabolism in active CD patients by reducing the inflammatory response.展开更多
文摘目的调查分析脑梗死患者临床流行病学特征,为脑梗死疾病预防和治疗工作提供依据。方法通过医院信息系统(Hospital Information System,HIS),按照脑梗死的国际疾病分类(International Classification of Diseases, ICD-10)(I63),采集2013—2017年江苏阜宁县中医院收治的主要诊断为脑梗死的首次住院患者病案首页信息,统计患者性别、年龄、疾病构成、入院时间、共病等情况。结果研究期间,累计出院脑梗死患者1 265人次,其中多发性脑梗死占比最高(45.77%)。男女性别比为1.60∶1,且性别间患者年龄构成存在差异(χ~2=19.765,P=0.001),60岁以上女性占比高于男性。第四季度脑梗死患者入院人数最多(27.11%)。脑梗死患者与高血压、高脂血症和糖尿病的共病率为64.11%,且女性共病率(69.75%)高于男性(60.59%),差异具有统计学意义(χ~2=10.920,P=0.001)。结论脑梗死住院患者呈现逐年增长趋势,且男性多于女性;脑梗死患者在出院诊断类别和入院时间分布均存在聚集性;脑梗死与高血压、高脂血症和糖尿病普遍具有共病现象。
文摘AIM: To investigate the impact of enteral nutrition(EN) on the body composition and metabolism in patientswith Crohn's disease(CD). METHODS: Sixty-one patients diagnosed with CD were enrolled in this study. They were given only EN(enteral nutritional suspension, TPF, non-elemental diet) support for 4 wk, without any treatment with corticosteroids, immunosuppressive drugs, infliximab or by surgical operation. Body composition statistics such as weight, body mass index, skeletal muscle mass(SMM), fat mass, protein mass and inflammation indexes such as C-reactive protein(CRP), erythrocyte sedimentation rate(ESR) and CD activity index(CDAI) were recorded before and after EN support. RESULTS: The 61 patients were divided into three groups according to CDAI before and after EN support: A(active phase into remission via EN, n = 21), B(remained in active phase before and after EN, n = 19) and C(in remission before and after EN, n = 21). Patients in group A had a significant increase in SMM(22.11 ± 4.77 kg vs 23.23 ± 4.49 kg, P = 0.044), protein mass(8.01 ± 1.57 kg vs 8.44 ± 1.45 kg, P = 0.019) and decrease in resting energy expenditure(REE) per kilogram(27.42 ± 5.01 kcal/kg per day vs 22.62 ± 5.45 kcal/kg per day, P < 0.05). There was no significant difference between predicted and measured REE in active CD patients according to the HarrisBenedict equation. There was no linear correlation between the measured REE and CRP, ESR or CDAI in active CD patients. CONCLUSION: EN could decrease the hypermetabolism in active CD patients by reducing the inflammatory response.
