Maturation is essential for dendritic cells(DCs)to function as a bridge between innate and adaptive immunity.The plastic maturation states correspond to the multifaceted roles of DCs in the initiation of protective,to...Maturation is essential for dendritic cells(DCs)to function as a bridge between innate and adaptive immunity.The plastic maturation states correspond to the multifaceted roles of DCs in the initiation of protective,tolerogenic and pathogenic immune responses.The formation of a distinct maturation state of DCs involves the complex crosstalk between the intrinsic differences in their ontogeny and the immune environments.Recent studies have defined a universal mature DC population in the tumor microenvironment(TME),but their ontogenesis and functions remain unclear.Here,we summarize recent advances in DC maturation and attempt to dissect the complex functions of mature DCs in the TME.We highlighted that there is a distinct similarity and heterogeneity of mature DCs in the TME,in which the environment and development are both important.These help us revisit the diversity of DC maturation and to better dissect the complex functions of DCs in the TME.展开更多
A series of shape-persistent polyphenylene dendritic C_(60)derivatives as the electron transport materials were designed and synthesized via a catalyst-free Diels-Alder[4+2]cycloaddition reaction.These increasing hype...A series of shape-persistent polyphenylene dendritic C_(60)derivatives as the electron transport materials were designed and synthesized via a catalyst-free Diels-Alder[4+2]cycloaddition reaction.These increasing hyperbranched scaffolds could effectively enhance the solubility;notably,both first and second generation dendrimers,C_(60)-G1 and C_(60)-G2,demonstrated more than 5 times higher solubilities than pristine C_(60).Furthermore,both simulated and experimental data proved their promising solution-processabilities as electron-transporting layers(ETLs)for perovskite solar cells.As a result,the planar p-i-n structural perovskite solar cell could achieve a maximum power conversion efficiency of 14.7%with C_(60)-G2.展开更多
Via a galvanic displacement reaction, well-defined micro/nano binary dendritic gold structures were prepared on silicon wafers in fluoride acid solution containing HAuCI4 at 50 ℃. The gold deposits were characterized...Via a galvanic displacement reaction, well-defined micro/nano binary dendritic gold structures were prepared on silicon wafers in fluoride acid solution containing HAuCI4 at 50 ℃. The gold deposits were characterized with scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) spectrum and X-ray diffraction (XRD). The investigation of the surface-enhanced Raman scattering (SERS) reveals that the film of gold dendrites was an excellent substrate with significant enhancement effect. Also, the gold dendritic structured surface exhibited a remarkable superhydrophobic property with a contact angle of approximately 165° and low contact angle hysteresis after further simple surface modification with n-dodecanethiol.展开更多
We study surface plasmon polaritons excited on two-dimensional three-order dendritic structures. Previous studies show that split ring resonators (SRRs) can be used to obtain magnetic resonance, thus sustairdng surf...We study surface plasmon polaritons excited on two-dimensional three-order dendritic structures. Previous studies show that split ring resonators (SRRs) can be used to obtain magnetic resonance, thus sustairdng surface waves behaving like surface plasmon polaritons (SPPs). In this paper, we obtain detailed results on surface plasmon polaritons of several different grating structures and theoretically prove that this kind of structures can sustain SPPs. Besides, since dendritic structures can be fabricated by double template-assisted electrochemical deposition, it is worth noting that fabrication of SPP-based materials might be much easier.展开更多
The sacrificial polymeric template usually used in lithographic methods could be replaced by crystalline materials such as ionic salts which, in some special conditions, can form arrays of single crystals. Atomic forc...The sacrificial polymeric template usually used in lithographic methods could be replaced by crystalline materials such as ionic salts which, in some special conditions, can form arrays of single crystals. Atomic force microscopy investigations performed on such samples show their regularity and nanometric thickness. They can serve as a part of an ionic/molecular crystal grid or as mask in crystal lithography. Alternating the polarity degree of the employed solvents/dispersing media by matching materials qualities, we fabricated a sodium chromate and sulphur crystalline net, iron oxide nanoparticle grid and a sulphur single crystal array. The lack of any expensive/sophisticated technology in the production process of final devices makes this approach attractive.展开更多
基金supported by the Major Program of Shenzhen Bay Laboratory(S201101004)the Open Program of Shenzhen Bay Laboratory(SZBL2020090501005)+1 种基金the National Natural Science Foundation of China(81988101,31991171,91959000)the Beijing Municipal Science and Technology Commission(Z211100003321005)
文摘Maturation is essential for dendritic cells(DCs)to function as a bridge between innate and adaptive immunity.The plastic maturation states correspond to the multifaceted roles of DCs in the initiation of protective,tolerogenic and pathogenic immune responses.The formation of a distinct maturation state of DCs involves the complex crosstalk between the intrinsic differences in their ontogeny and the immune environments.Recent studies have defined a universal mature DC population in the tumor microenvironment(TME),but their ontogenesis and functions remain unclear.Here,we summarize recent advances in DC maturation and attempt to dissect the complex functions of mature DCs in the TME.We highlighted that there is a distinct similarity and heterogeneity of mature DCs in the TME,in which the environment and development are both important.These help us revisit the diversity of DC maturation and to better dissect the complex functions of DCs in the TME.
基金Projects(2017YFE0131900,2017YFB0404500)supported by National Key Research and Development Program of ChinaProjects(91833306,91733302,62075094)supported by the National Natural Science Foundation of China+1 种基金Project(202003N4004)supported by the Ningbo Natural Science Foundation,ChinaProject(2020GXLH-Z-014)supported by the Joint Research Funds of Department of Science&Technology of Shaanxi Province and Northwestern Polytechnical University,China。
文摘A series of shape-persistent polyphenylene dendritic C_(60)derivatives as the electron transport materials were designed and synthesized via a catalyst-free Diels-Alder[4+2]cycloaddition reaction.These increasing hyperbranched scaffolds could effectively enhance the solubility;notably,both first and second generation dendrimers,C_(60)-G1 and C_(60)-G2,demonstrated more than 5 times higher solubilities than pristine C_(60).Furthermore,both simulated and experimental data proved their promising solution-processabilities as electron-transporting layers(ETLs)for perovskite solar cells.As a result,the planar p-i-n structural perovskite solar cell could achieve a maximum power conversion efficiency of 14.7%with C_(60)-G2.
文摘Via a galvanic displacement reaction, well-defined micro/nano binary dendritic gold structures were prepared on silicon wafers in fluoride acid solution containing HAuCI4 at 50 ℃. The gold deposits were characterized with scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) spectrum and X-ray diffraction (XRD). The investigation of the surface-enhanced Raman scattering (SERS) reveals that the film of gold dendrites was an excellent substrate with significant enhancement effect. Also, the gold dendritic structured surface exhibited a remarkable superhydrophobic property with a contact angle of approximately 165° and low contact angle hysteresis after further simple surface modification with n-dodecanethiol.
基金Supported by the National Natural Science Foundation of China under Grants Nos. 10974030 and 10574027
文摘We study surface plasmon polaritons excited on two-dimensional three-order dendritic structures. Previous studies show that split ring resonators (SRRs) can be used to obtain magnetic resonance, thus sustairdng surface waves behaving like surface plasmon polaritons (SPPs). In this paper, we obtain detailed results on surface plasmon polaritons of several different grating structures and theoretically prove that this kind of structures can sustain SPPs. Besides, since dendritic structures can be fabricated by double template-assisted electrochemical deposition, it is worth noting that fabrication of SPP-based materials might be much easier.
文摘The sacrificial polymeric template usually used in lithographic methods could be replaced by crystalline materials such as ionic salts which, in some special conditions, can form arrays of single crystals. Atomic force microscopy investigations performed on such samples show their regularity and nanometric thickness. They can serve as a part of an ionic/molecular crystal grid or as mask in crystal lithography. Alternating the polarity degree of the employed solvents/dispersing media by matching materials qualities, we fabricated a sodium chromate and sulphur crystalline net, iron oxide nanoparticle grid and a sulphur single crystal array. The lack of any expensive/sophisticated technology in the production process of final devices makes this approach attractive.