The Synthetic Aperture Radar(SAR)raw data generator is required to the evaluation of focusing algorithms,moving target analysis,and hardware design.The time-domain SAR simulator can generate the accurate raw data but ...The Synthetic Aperture Radar(SAR)raw data generator is required to the evaluation of focusing algorithms,moving target analysis,and hardware design.The time-domain SAR simulator can generate the accurate raw data but it needs much time.The frequency-domain simulator not only increases the efficiency but also considers the trajectory deviations of the radar.In addition,the raw signal of the extended scene included static and moving targets can be generated by some frequency-domain simulators.However,the existing simulators concentrate on the raw signal simulation of the static extended scene and moving targets at uniform speed mostly.As for the issue,the two-dimensional signal spectrum of moving targets with constant acceleration can be derived accurately based on the geometric model of a side-looking SAR and reversion of series.And a frequency-domain algorithm for SAR echo signal simulation is presented based on the two-dimensional signal spectrum.The raw data generated with proposed method is verified by several simulation experiments.In addition to reveal the efficiency of the presented frequency-domain SAR scene simulator,the computational complexity of the proposed method is compared with the time-domain approach using the complex multiplication.Numerical results demonstrate that the present method can reduce the computational time significantly without accuracy loss while simulating SAR raw data.展开更多
文摘目的将共享随机效应模型(shared random-effect model,SREM)应用于轻度认知障碍(mild cognitive impairment,MCI)向认知正常(normal cognition,NC)逆转的研究,比较不同纵向认知标志物对MCI逆转的预测性能,并评价影响因素的协变量效应。方法SREM模型包括两个子模型,其中纵向子模型采用线性混合效应模型对纵向认知标志物的变化轨迹建模,生存子模型采用比例风险模型对生存过程建模。基于对数似然函数值和信息准则进行模型拟合优度检验,采用ROC曲线下面积(area under the curve,AUC)评价不同纵向认知标志物(MMSE、CDRSB、FAQ、ADAS11、ADAS13和ADASQ4)对MCI逆转的预测性能;同时进行纵向子模型和生存子模型的影响因素分析。结果843名MCI患者中72名(8.54%)在随访结束后逆转为NC。以spline-PH-GH参数分布为基准风险函数的SREM模型对数似然函数值最大,AIC和BIC最小;以CDRSB为纵向认知标志物建立的SREM模型拟合最好,在不同时间的AUC值均表现良好,范围为0.797~0.852,且预测误差最小,范围为0.0427~0.0429;年龄、性别、受教育程度、婚姻状况和APOEε4基因均会影响MCI患者的认知功能和日常活动功能,六种纵向认知标志物均会影响MCI患者的逆转。结论CDR评分对MCI患者的认知功能和逆转预测性能最佳;认知功能和日常活动功能可作为MCI逆转的动态监测指标。
基金The work was supported by the Natural Science Foundation of Shandong Province,China.(Grant No.ZR2017BF032)。
文摘The Synthetic Aperture Radar(SAR)raw data generator is required to the evaluation of focusing algorithms,moving target analysis,and hardware design.The time-domain SAR simulator can generate the accurate raw data but it needs much time.The frequency-domain simulator not only increases the efficiency but also considers the trajectory deviations of the radar.In addition,the raw signal of the extended scene included static and moving targets can be generated by some frequency-domain simulators.However,the existing simulators concentrate on the raw signal simulation of the static extended scene and moving targets at uniform speed mostly.As for the issue,the two-dimensional signal spectrum of moving targets with constant acceleration can be derived accurately based on the geometric model of a side-looking SAR and reversion of series.And a frequency-domain algorithm for SAR echo signal simulation is presented based on the two-dimensional signal spectrum.The raw data generated with proposed method is verified by several simulation experiments.In addition to reveal the efficiency of the presented frequency-domain SAR scene simulator,the computational complexity of the proposed method is compared with the time-domain approach using the complex multiplication.Numerical results demonstrate that the present method can reduce the computational time significantly without accuracy loss while simulating SAR raw data.