The Dose Volume Histograms are tools commonly used in medical physics, for the analysis of doses delivered to the tumors and organs at risk, during radiotherapy treatments. However, there are few studies in the litera...The Dose Volume Histograms are tools commonly used in medical physics, for the analysis of doses delivered to the tumors and organs at risk, during radiotherapy treatments. However, there are few studies in the literature showing in details the steps of its construction. This work presents the implementation and evaluation of a computational methodology, for the construction of Dose Volume histograms, generated from simulations using anthropomorphic and voxel phantoms, in conjunction with the Monte Carlo code MCNP. The methodology was evaluated considering brachytherapy planning of low dose rate, using 108 seeds of I-125 with individual activities of 0.33 mCi performed on the simulator in voxel recommended by ICRP 110. The dosimetric analysis after implantation showed that the prostate received doses ranging from 0 to 360 Gy. We found the values of 50, 145 and 160 Gy for the parameters D<sub>100</sub>, D<sub>90</sub> and D<sub>80</sub> and 28%, 90%, 92% and 95% for the parameters V<sub>200</sub>, V<sub>100</sub>, V<sub>90</sub> and V<sub>80</sub>. The rectum and bladder received maximum doses equal to 41 and 60 Gy and found the values of 39 and 22 Gy and 58 and 42 Gy to the parameters D<sub>0.1cc</sub> and D<sub>2cc</sub>, respectively. The results after dosimetric implant proved satisfactory, which validate the methodology described above.展开更多
文摘The Dose Volume Histograms are tools commonly used in medical physics, for the analysis of doses delivered to the tumors and organs at risk, during radiotherapy treatments. However, there are few studies in the literature showing in details the steps of its construction. This work presents the implementation and evaluation of a computational methodology, for the construction of Dose Volume histograms, generated from simulations using anthropomorphic and voxel phantoms, in conjunction with the Monte Carlo code MCNP. The methodology was evaluated considering brachytherapy planning of low dose rate, using 108 seeds of I-125 with individual activities of 0.33 mCi performed on the simulator in voxel recommended by ICRP 110. The dosimetric analysis after implantation showed that the prostate received doses ranging from 0 to 360 Gy. We found the values of 50, 145 and 160 Gy for the parameters D<sub>100</sub>, D<sub>90</sub> and D<sub>80</sub> and 28%, 90%, 92% and 95% for the parameters V<sub>200</sub>, V<sub>100</sub>, V<sub>90</sub> and V<sub>80</sub>. The rectum and bladder received maximum doses equal to 41 and 60 Gy and found the values of 39 and 22 Gy and 58 and 42 Gy to the parameters D<sub>0.1cc</sub> and D<sub>2cc</sub>, respectively. The results after dosimetric implant proved satisfactory, which validate the methodology described above.