The Internet of Vehicles(IoV)has been widely researched in recent years,and cloud computing has been one of the key technologies in the IoV.Although cloud computing provides high performance compute,storage and networ...The Internet of Vehicles(IoV)has been widely researched in recent years,and cloud computing has been one of the key technologies in the IoV.Although cloud computing provides high performance compute,storage and networking services,the IoV still suffers with high processing latency,less mobility support and location awareness.In this paper,we integrate fog computing and software defined networking(SDN) to address those problems.Fog computing extends computing and storing to the edge of the network,which could decrease latency remarkably in addition to enable mobility support and location awareness.Meanwhile,SDN provides flexible centralized control and global knowledge to the network.In order to apply the software defined cloud/fog networking(SDCFN) architecture in the IoV effectively,we propose a novel SDN-based modified constrained optimization particle swarm optimization(MPSO-CO) algorithm which uses the reverse of the flight of mutation particles and linear decrease inertia weight to enhance the performance of constrained optimization particle swarm optimization(PSO-CO).The simulation results indicate that the SDN-based MPSO-CO algorithm could effectively decrease the latency and improve the quality of service(QoS) in the SDCFN architecture.展开更多
The integrated information network is a large capacity information network that integrates various communication platforms on the ground, at sea, in the air and in the deep air through the inter-satellite and satellit...The integrated information network is a large capacity information network that integrates various communication platforms on the ground, at sea, in the air and in the deep air through the inter-satellite and satellite-ground links to acquire information accurately, process it quickly, and transmit it efficiently. The satellite communication, as an important part of integrated information networks, is one of main approaches to acquire, process and distribute communication information and resources. In this paper, based on current researches of the satellite communication network, we put forward a 3-layer satellite communication network model based on the Software Defined Network (SDN). Meanwhile, to improve current routing policies of the Low Earth Orbit (LEO) satellite communication network, we put forward an Adaptive Routing Algorithm (ARA) to sustain the shortest satellite communication link. Experiment results show that the proposed method can effectively reduce link distance and communication delay, and realize adaptive path planning.展开更多
Aim:To establish a method for cynomolgus monkey sperm cryopreservation in a chemically defined extender. Methods:Semen samples were collected by electro-ejaculation from four sexually mature male cynomolgus monkeys. T...Aim:To establish a method for cynomolgus monkey sperm cryopreservation in a chemically defined extender. Methods:Semen samples were collected by electro-ejaculation from four sexually mature male cynomolgus monkeys. The spermatozoa were frozen in straws by liquid nitrogen vapor using egg-yolk-free Tes-Tris (mTTE) synthetic extender and glycerol as cryoprotectant.The effects of glycerol concentration (1%,3 %,5 %,10 % and 15 % [v/v]) and its equilibration time (10 min,30 min,60 min and 90 min) on post-thaw spermatozoa were examined by sperm motility and sperm head membrane integrity.Results:The post-thaw motility and head membrane integrity of spermatozoa were significantly higher (P<0.05) for 5 % glycerol (42.95±2.55 and 50.39±2.42,respectively) than those of the other groups (1%:19.19±3.22 and 24.84±3.64;3 %:34.23±3.43 and 41.37±3.42;10 %: 15.68±2.36 and 21.39±3.14;15 %:7.47±1.44 and 12.90±2.18).The parameters for 30 min equilibration (42.95±2.55 and 50.39±2.42) were better (P<0.05) than those of the other groups (10 min:31.33±3.06 and 38. 98±3.31;60 min:32.49±3.86 and 40.01±4.18;90 min:31.16±3.66 and 38.30±3.78).Five percent glycerol and 30 min equilibration yielded the highest post-thaw sperm motility and head membrane integrity.Conclusion: Cynomolgus monkey spermatozoa can be successfully cryopreserved in a chemically defined extender,which is related to the concentration and the equilibration time of glycerol.展开更多
The co-existence of multiple cell components in tissue samples is the main obstacle for precise molecular evaluation on defined cell types. Based on morphological examination, we developed an efficient approach for pa...The co-existence of multiple cell components in tissue samples is the main obstacle for precise molecular evaluation on defined cell types. Based on morphological examination, we developed an efficient approach for paralleled RNA and protein isolations from an identical histological region in frozen tissue section.The RNA and protein samples prepared were sufficient for RT-PCR and Western blot analyses, and the results obtained were well coincident each other as well as with the corresponding parameters revealed from immunohistochemical examinations. By this way, the sampling problem caused by cell-cross contamination can be largely avoided, committing the experimental data more specific to a defined cell type. These novel methods thus allow us to use single tissue block for a comprehensive study by integration of conventional cytological evaluations with nucleic acid and protein analyses.展开更多
As an indispensable component of the emerging 6G networks,Space-Air-Ground Inte-grated Networks(SAGINs)are envisioned to provide ubiquitous network connectivity and services by integrating satellite networks,aerial ne...As an indispensable component of the emerging 6G networks,Space-Air-Ground Inte-grated Networks(SAGINs)are envisioned to provide ubiquitous network connectivity and services by integrating satellite networks,aerial networks,and terrestrial networks.In 6G SAGINs,a wide variety of network services with the features of diverse requirements,complex mobility,and multi-dimensional resources will pose great challenges to service provisioning,which urges the develop-ment of service-oriented SAGINs.In this paper,we conduct a comprehensive review of 6G SAGINs from a new perspective of service-oriented network.First,we present the requirements of service-oriented networks,and then propose a service-oriented SAGINs management architec-ture.Two categories of critical technologies are presented and discussed,i.e.,heterogeneous resource orchestration technologies and the cloud-edge synergy technologies,which facilitate the interoperability of different network segments and cooperatively orchestrate heterogeneous resources across different domains,according to the service features and requirements.In addition,the potential future research directions are also presented and discussed.展开更多
In order to improve the scalability and reliability of Software Defined Networking(SDN),many studies use multiple controllers to constitute logically centralized control plane to provide load balancing and fail over.I...In order to improve the scalability and reliability of Software Defined Networking(SDN),many studies use multiple controllers to constitute logically centralized control plane to provide load balancing and fail over.In this paper,we develop a flexible dormant multi-controller model based on the centralized multi-controller architecture.The dormant multi-controller model allows part of controllers to enter the dormant state under light traffic condition for saving system cost.Meanwhile,through queueing analysis,various performance measures of the system can be obtained.Moreover,we analyze the real traffic of China Education Network and use the results as the parameters of computer simulation and verify the effects of parameters on the system characteristics.Finally,a total expected cost function is established,and genetic algorithm is employed to find the optimal values of various parameters to minimize system cost for the deployment decision making.展开更多
Software Defined Networking(SDN) is a revolutionary networking paradigm towards the future network,experiencing rapid development nowadays.However,its main characteristic,the separation of control plane and data plane...Software Defined Networking(SDN) is a revolutionary networking paradigm towards the future network,experiencing rapid development nowadays.However,its main characteristic,the separation of control plane and data plane,also brings about new security challenges,i.e.,Denial-of-Service(DoS) attacks specific to Open Flow SDN networks to exhaust the control plane bandwidth and overload the buffer memory of Open Flow switch.To mitigate the DoS attacks in the Open Flow networks,we design and implement SGuard,a security application on top of the NOX controller that mainly contains two modules:Access control module and Classification module.We employ novel six-tuple as feature vector to classify traffic flows,meanwhile optimizing classification by feature ranking and selecting algorithms.All the modules will cooperate with each other to complete a series of tasks such as authorization,classification and so on.At the end of this paper,we experimentally use Mininet to evaluate SGuard in a software environment.The results show that SGuard works efficiently and accurately without adding more overhead to the SDN networks.展开更多
As communication technology and smart manufacturing have developed, the industrial internet of things(IIo T)has gained considerable attention from academia and industry.Wireless sensor networks(WSNs) have many advanta...As communication technology and smart manufacturing have developed, the industrial internet of things(IIo T)has gained considerable attention from academia and industry.Wireless sensor networks(WSNs) have many advantages with broad applications in many areas including environmental monitoring, which makes it a very important part of IIo T. However,energy depletion and hardware malfunctions can lead to node failures in WSNs. The industrial environment can also impact the wireless channel transmission, leading to network reliability problems, even with tightly coupled control and data planes in traditional networks, which obviously also enhances network management cost and complexity. In this paper, we introduce a new software defined network(SDN), and modify this network to propose a framework called the improved software defined wireless sensor network(improved SD-WSN). This proposed framework can address the following issues. 1) For a large scale heterogeneous network, it solves the problem of network management and smooth merging of a WSN into IIo T. 2) The network coverage problem is solved which improves the network reliability. 3) The framework addresses node failure due to various problems, particularly related to energy consumption.Therefore, it is necessary to improve the reliability of wireless sensor networks, by developing certain schemes to reduce energy consumption and the delay time of network nodes under IIo T conditions. Experiments have shown that the improved approach significantly reduces the energy consumption of nodes and the delay time, thus improving the reliability of WSN.展开更多
Tailored surface textures at the micro- or nanoscale dimensions are widely used to get required functional performances. Rotary ultrasonic texturing （RUT） technique has been proved to be capable of fabricating perio...Tailored surface textures at the micro- or nanoscale dimensions are widely used to get required functional performances. Rotary ultrasonic texturing （RUT） technique has been proved to be capable of fabricating periodic micro- and nanostructures. In the present study, diamond tools with geometrically defined cutting edges were designed for fabricating different types of tailored surface textures using the RUT method. Surface generation mechanisms and machinable structures of the RUT process are analyzed and simulated with a 3D-CAD program. Textured surfaces generated by using a triangular pyramid cutting tip are constructed. Different textural patterns from several micrometers to several tens of micrometers with few burrs were successfully fabricated, which proved that tools with a proper two-rake-face design are capable of removing cutting chips efficiently along a sinusoidal cutting locus in the RUT process. Technical applications of the textured surfaces are also discussed. Wetting properties of textured aluminum surfaces were evaluated by combining the test of surface roughness features. The results show that the real surface area of the textured aluminum surfaces almost doubled by comparing with that of a flat surface, and anisotropic wetting properties were obtained due to the obvious directional textural features.展开更多
[Objective] The aim was to isolate and identify a taxol-producing endophytic fungus from Taxus media. [Method] 32 strains of endophytic fungi were identified form the inner bark of T. media,and their fermentation prod...[Objective] The aim was to isolate and identify a taxol-producing endophytic fungus from Taxus media. [Method] 32 strains of endophytic fungi were identified form the inner bark of T. media,and their fermentation products were detected by high performance liquid chromatography (HPLC). [Result] Through the screening,a strain of taxol-producing endophytic fungi M57 was obtained,which could produce 45-50 μg/L of taxol,and M57 was defined as Rhizopus sp. through morphological observation and 18S rDNA sequence analysis. [Conclusion] The finding of Rhizopus sp. M57 provided a promising strain for producing taxol with taxol-producing fungi fermentation process.展开更多
This paper aims to derive the time-consistent investment strategy for the defined contribution(DC) pension plan under the mean-variance criterion.The financial market consists of a risk-free asset and a risky asset of...This paper aims to derive the time-consistent investment strategy for the defined contribution(DC) pension plan under the mean-variance criterion.The financial market consists of a risk-free asset and a risky asset of which price process satisfies the constant elasticity of variance(CEV) model.Compared with the geometric Brownian motion model,the CEV model has the ability of capturing the implied volatility skew and explaining the volatility smile.The authors assume that the contribution to the pension fund is a constant proportion of the pension member's salary.Meanwhile,the salary is stochastic and its volatility arises from the price process of the risky asset,which makes the proposed model different from most of existing researches and more realistic.In the proposed model,the optimization problem can be decomposed into two sub-problems:Before and after retirement cases.By applying a game theoretic framework and solving extended Hamilton-Jacobi-Bellman(HJB) systems,the authors derive the time-consistent strategies and the corresponding value functions explicitly.Finally,numerical simulations are presented to illustrate the effects of model parameters on the time-consistent strategies.展开更多
Publish/subscribe paradigm paves a way to integrate and serve many scalable, inter-operable Internet of Things(IoT) applications. The increasing IoT applications require new properties of publish/subscribe communicati...Publish/subscribe paradigm paves a way to integrate and serve many scalable, inter-operable Internet of Things(IoT) applications. The increasing IoT applications require new properties of publish/subscribe communication model, for example, strict quality of service(Qo S) guarantees, supporting a large number of widely distributed devices, etc. Software Defined Networking(SDN) enables personalized programming and individualized QoS supports for different applications. The combination of the two will have a good prospect. In this paper, we present an IoT-oriented communication platform which combines the publish/subscribe paradigm with SDN, aiming at establishing an IoT ecosystem to facilitate IoT services/applications accessing internet. We design the interaction logic of topic-based publish/subscribe middleware, and describe the setup and maintenance of topology information as well as event routing in detail, considering the characteristics of SDN. Finally, we exemplify its practicability with a deployed District Heating Control and Information Service System(DHCISS) and validity the effectiveness with some experiments.展开更多
Background Keratinoyte serum-free medium （K-SFM） is a defined medium used to support the growth of primary keratinocytes and embryonic stem cell. The aim of this research was to optimize enrichment of breast cancer ...Background Keratinoyte serum-free medium （K-SFM） is a defined medium used to support the growth of primary keratinocytes and embryonic stem cell. The aim of this research was to optimize enrichment of breast cancer stem cells （CSCs） using K-SFM. Methods＇ A K-SFM was used to enrich CSCs from two breast cancer cell lines and a primary culture of breast cancer. RPMI-1640 supplemented with 10% fetal calf serum （FCS） was used as a control. CSCs were identified with flow cytometry using CD44＋/CD24-as molecular markers. The expression of a variety of CSC markers （Oct-4, ABCG2, Nanog, N-cadherin, and E-cadherin） was analyzed with real-time PCR. Results Much higher percentage of CSCs was achieved with K-SFM： 17.3% for MCF-7 cells, 17.4% for SKBR-3, and 20.0% for primary breast cancer culture. Less than 1% CSC was achieved using RPMI-1640 supplemented with 10% FCS. In comparison to the CSCs obtained with RPMI-1640, CSCs in the K-SFM expressed higher levels of Oct-4, ABCG2, Nanog and N-cadherin, and lower level of E-cadherin. Conclusion K-SFM is an optimal culture medium to maintain and to enrich breast CSCs.展开更多
针对典型蜂窝网络LTE-A网络的切换认证问题,本文通过引入SDN(Software Defined Network,软件定义网络),提出了软件定义LTE-A异构网络架构,在中心控制器中共享UE(User Equipment,用户设备)的安全上下文信息,以实现简化切换认证过程,提高...针对典型蜂窝网络LTE-A网络的切换认证问题,本文通过引入SDN(Software Defined Network,软件定义网络),提出了软件定义LTE-A异构网络架构,在中心控制器中共享UE(User Equipment,用户设备)的安全上下文信息,以实现简化切换认证过程,提高认证效率的目标.中心控制器的加入,使蜂窝与核心网通信时需要增加一次信令开销,而LTE-A网络的标准切换认证方法过于复杂,应用在软件定义LTE-A异构网络中,会产生较多的信令开销.基于代理签名的切换认证方法,使UE在验证身份时不用经过核心网,减少了信令开销.在安全性相同的情况下,基于椭圆曲线的加密体系比基于RSA的加密体系计算量更小,有利于减少中心控制器的计算压力.本文采用椭圆曲线代理签名方法,提出了一种新型的切换认证协议,并运用着色Petri网进行建模和仿真分析.仿真结果表明,该协议是有效的,且安全性更高.展开更多
An improved and efficient DEM-CFD approach is developed for spouted beds. A nonlinear Discrete Element Method （DEM）, with a concept of spring, dash-pot and friction slider, is used for tracing the movement of each i...An improved and efficient DEM-CFD approach is developed for spouted beds. A nonlinear Discrete Element Method （DEM）, with a concept of spring, dash-pot and friction slider, is used for tracing the movement of each individual particle. The gas flow is described by a set of reorganized governing equations. Two phases are coupled through contributions due to effects of porosity, viscosity and drag. All equations are solved with the commercial package Fluent with an implementation of User Defined Functions （UDF）. To validate the improved model, a two-dimensional conical-base spouted bed is chosen as a case study. An unstructured mesh system is adopted instead of regular grid system. The simulation also takes the Saffman force and Magnus effect into account. The calculation results show good agreement with the experimental observations which are taken from the literature.展开更多
With the continuous expansion of the data center network scale, changing network requirements, and increasing pressure on network bandwidth, the traditional network architecture can no longer meet people’s needs. The...With the continuous expansion of the data center network scale, changing network requirements, and increasing pressure on network bandwidth, the traditional network architecture can no longer meet people’s needs. The development of software defined networks has brought new opportunities and challenges to future networks. The data and control separation characteristics of SDN improve the performance of the entire network. Researchers have integrated SDN architecture into data centers to improve network resource utilization and performance. This paper first introduces the basic concepts of SDN and data center networks. Then it discusses SDN-based load balancing mechanisms for data centers from different perspectives. Finally, it summarizes and looks forward to the study on SDN-based load balancing mechanisms and its development trend.展开更多
Traditional traffic management techniques appear to be incompetent in complex data center networks, so proposes a load balancing strategy based on Long Short-Term Memory (LSTM) and quantum annealing by Software Define...Traditional traffic management techniques appear to be incompetent in complex data center networks, so proposes a load balancing strategy based on Long Short-Term Memory (LSTM) and quantum annealing by Software Defined Network (SDN) to dynamically predict the traffic and comprehensively consider the current and predicted load of the network in order to select the optimal forwarding path and balance the network load. Experiments have demonstrated that the algorithm achieves significant improvement in both system throughput and average packet loss rate for the purpose of improving network quality of service.展开更多
Software Defined Networking(SDN) provides flexible network management by decoupling control plane and data plane. However, such separation introduces the issues regarding the reliability of the control plane and contr...Software Defined Networking(SDN) provides flexible network management by decoupling control plane and data plane. However, such separation introduces the issues regarding the reliability of the control plane and controller load imbalance in the distributed SDN network, which will cause the low network stability and the poor controller performance. This paper proposes Reliable and Load balance-aware Multi-controller Deployment(RLMD) strategy to address the above problems. Firstly, we establish a multiple-controller network model and define the relevant parameters for RLMD. Then, we design the corresponding algorithms to implement this strategy. By weighing node efficiency and path quality, Controller Placement Selection(CPS) algorithm is introduced to explore the reliable deployments of the controllers. On this basis, we design Multiple Domain Partition(MDP) algorithm to allocate switches for controllers according to node attractability and controller load balancing rate, which could realize the reasonable domain planning. Finally, the simulations show that, compared with the typical strategies, RLMD has the better performance in improving the reliability of the control plane and balancing the distribution of the controller loads.展开更多
基金supported in part by National Natural Science Foundation of China (No.61401331,No.61401328)111 Project in Xidian University of China(B08038)+2 种基金Hong Kong,Macao and Taiwan Science and Technology Cooperation Special Project (2014DFT10320,2015DFT10160)The National Science and Technology Major Project of the Ministry of Science and Technology of China(2015zx03002006-003)FundamentalResearch Funds for the Central Universities (20101155739)
文摘The Internet of Vehicles(IoV)has been widely researched in recent years,and cloud computing has been one of the key technologies in the IoV.Although cloud computing provides high performance compute,storage and networking services,the IoV still suffers with high processing latency,less mobility support and location awareness.In this paper,we integrate fog computing and software defined networking(SDN) to address those problems.Fog computing extends computing and storing to the edge of the network,which could decrease latency remarkably in addition to enable mobility support and location awareness.Meanwhile,SDN provides flexible centralized control and global knowledge to the network.In order to apply the software defined cloud/fog networking(SDCFN) architecture in the IoV effectively,we propose a novel SDN-based modified constrained optimization particle swarm optimization(MPSO-CO) algorithm which uses the reverse of the flight of mutation particles and linear decrease inertia weight to enhance the performance of constrained optimization particle swarm optimization(PSO-CO).The simulation results indicate that the SDN-based MPSO-CO algorithm could effectively decrease the latency and improve the quality of service(QoS) in the SDCFN architecture.
基金supported in part by the National Natural Science Foundation of China (No. 61571104)the Sichuan Science and Technology Program (No. 2018JY0539)+2 种基金the Key projects of the Sichuan Provincial Education Department (No. 18ZA0219)the Fundamental Research Funds for the Central Universities (No. ZYGX2017KYQD170)the Innovation Funding (No. 2018510007000134)
文摘The integrated information network is a large capacity information network that integrates various communication platforms on the ground, at sea, in the air and in the deep air through the inter-satellite and satellite-ground links to acquire information accurately, process it quickly, and transmit it efficiently. The satellite communication, as an important part of integrated information networks, is one of main approaches to acquire, process and distribute communication information and resources. In this paper, based on current researches of the satellite communication network, we put forward a 3-layer satellite communication network model based on the Software Defined Network (SDN). Meanwhile, to improve current routing policies of the Low Earth Orbit (LEO) satellite communication network, we put forward an Adaptive Routing Algorithm (ARA) to sustain the shortest satellite communication link. Experiment results show that the proposed method can effectively reduce link distance and communication delay, and realize adaptive path planning.
文摘Aim:To establish a method for cynomolgus monkey sperm cryopreservation in a chemically defined extender. Methods:Semen samples were collected by electro-ejaculation from four sexually mature male cynomolgus monkeys. The spermatozoa were frozen in straws by liquid nitrogen vapor using egg-yolk-free Tes-Tris (mTTE) synthetic extender and glycerol as cryoprotectant.The effects of glycerol concentration (1%,3 %,5 %,10 % and 15 % [v/v]) and its equilibration time (10 min,30 min,60 min and 90 min) on post-thaw spermatozoa were examined by sperm motility and sperm head membrane integrity.Results:The post-thaw motility and head membrane integrity of spermatozoa were significantly higher (P<0.05) for 5 % glycerol (42.95±2.55 and 50.39±2.42,respectively) than those of the other groups (1%:19.19±3.22 and 24.84±3.64;3 %:34.23±3.43 and 41.37±3.42;10 %: 15.68±2.36 and 21.39±3.14;15 %:7.47±1.44 and 12.90±2.18).The parameters for 30 min equilibration (42.95±2.55 and 50.39±2.42) were better (P<0.05) than those of the other groups (10 min:31.33±3.06 and 38. 98±3.31;60 min:32.49±3.86 and 40.01±4.18;90 min:31.16±3.66 and 38.30±3.78).Five percent glycerol and 30 min equilibration yielded the highest post-thaw sperm motility and head membrane integrity.Conclusion: Cynomolgus monkey spermatozoa can be successfully cryopreserved in a chemically defined extender,which is related to the concentration and the equilibration time of glycerol.
基金This work was supported in part by NationalNatural Science Foundation of China(No.39470767and No.396101300419)and by a special grantfrom Liaoning Provincial Committee for Science andTechnology,China(No.963010)
文摘The co-existence of multiple cell components in tissue samples is the main obstacle for precise molecular evaluation on defined cell types. Based on morphological examination, we developed an efficient approach for paralleled RNA and protein isolations from an identical histological region in frozen tissue section.The RNA and protein samples prepared were sufficient for RT-PCR and Western blot analyses, and the results obtained were well coincident each other as well as with the corresponding parameters revealed from immunohistochemical examinations. By this way, the sampling problem caused by cell-cross contamination can be largely avoided, committing the experimental data more specific to a defined cell type. These novel methods thus allow us to use single tissue block for a comprehensive study by integration of conventional cytological evaluations with nucleic acid and protein analyses.
基金supported by the National Key Research and Development Program of China(No.2020YFB1807700).
文摘As an indispensable component of the emerging 6G networks,Space-Air-Ground Inte-grated Networks(SAGINs)are envisioned to provide ubiquitous network connectivity and services by integrating satellite networks,aerial networks,and terrestrial networks.In 6G SAGINs,a wide variety of network services with the features of diverse requirements,complex mobility,and multi-dimensional resources will pose great challenges to service provisioning,which urges the develop-ment of service-oriented SAGINs.In this paper,we conduct a comprehensive review of 6G SAGINs from a new perspective of service-oriented network.First,we present the requirements of service-oriented networks,and then propose a service-oriented SAGINs management architec-ture.Two categories of critical technologies are presented and discussed,i.e.,heterogeneous resource orchestration technologies and the cloud-edge synergy technologies,which facilitate the interoperability of different network segments and cooperatively orchestrate heterogeneous resources across different domains,according to the service features and requirements.In addition,the potential future research directions are also presented and discussed.
基金the National High-tech R&D Program ("863" Program) of China，the National Science Foundation of China，National Science & Technology Pillar Program of China，the National Science Foundation of China，the Post-Doctoral Funding of China，Tsinghua-Huawei joint research project
文摘In order to improve the scalability and reliability of Software Defined Networking(SDN),many studies use multiple controllers to constitute logically centralized control plane to provide load balancing and fail over.In this paper,we develop a flexible dormant multi-controller model based on the centralized multi-controller architecture.The dormant multi-controller model allows part of controllers to enter the dormant state under light traffic condition for saving system cost.Meanwhile,through queueing analysis,various performance measures of the system can be obtained.Moreover,we analyze the real traffic of China Education Network and use the results as the parameters of computer simulation and verify the effects of parameters on the system characteristics.Finally,a total expected cost function is established,and genetic algorithm is employed to find the optimal values of various parameters to minimize system cost for the deployment decision making.
基金supported by the National key Research and Development Program of China(No.2016YFB0800100,2016YFB0800101)the National Natural Science Fund for Creative Research Groups Project(No.61521003)the National Natural Science Fund for Youth Found Project(No.61602509)
文摘Software Defined Networking(SDN) is a revolutionary networking paradigm towards the future network,experiencing rapid development nowadays.However,its main characteristic,the separation of control plane and data plane,also brings about new security challenges,i.e.,Denial-of-Service(DoS) attacks specific to Open Flow SDN networks to exhaust the control plane bandwidth and overload the buffer memory of Open Flow switch.To mitigate the DoS attacks in the Open Flow networks,we design and implement SGuard,a security application on top of the NOX controller that mainly contains two modules:Access control module and Classification module.We employ novel six-tuple as feature vector to classify traffic flows,meanwhile optimizing classification by feature ranking and selecting algorithms.All the modules will cooperate with each other to complete a series of tasks such as authorization,classification and so on.At the end of this paper,we experimentally use Mininet to evaluate SGuard in a software environment.The results show that SGuard works efficiently and accurately without adding more overhead to the SDN networks.
基金supported by the National Natural Science Foundation of China(61571336)the Science and Technology Project of Henan Province in China(172102210081)the Independent Innovation Research Foundation of Wuhan University of Technology(2016-JL-036)
文摘As communication technology and smart manufacturing have developed, the industrial internet of things(IIo T)has gained considerable attention from academia and industry.Wireless sensor networks(WSNs) have many advantages with broad applications in many areas including environmental monitoring, which makes it a very important part of IIo T. However,energy depletion and hardware malfunctions can lead to node failures in WSNs. The industrial environment can also impact the wireless channel transmission, leading to network reliability problems, even with tightly coupled control and data planes in traditional networks, which obviously also enhances network management cost and complexity. In this paper, we introduce a new software defined network(SDN), and modify this network to propose a framework called the improved software defined wireless sensor network(improved SD-WSN). This proposed framework can address the following issues. 1) For a large scale heterogeneous network, it solves the problem of network management and smooth merging of a WSN into IIo T. 2) The network coverage problem is solved which improves the network reliability. 3) The framework addresses node failure due to various problems, particularly related to energy consumption.Therefore, it is necessary to improve the reliability of wireless sensor networks, by developing certain schemes to reduce energy consumption and the delay time of network nodes under IIo T conditions. Experiments have shown that the improved approach significantly reduces the energy consumption of nodes and the delay time, thus improving the reliability of WSN.
基金Supported by Japan Society for the Promotion of Science(Grant Nos.14J04115,16K17990)
文摘Tailored surface textures at the micro- or nanoscale dimensions are widely used to get required functional performances. Rotary ultrasonic texturing （RUT） technique has been proved to be capable of fabricating periodic micro- and nanostructures. In the present study, diamond tools with geometrically defined cutting edges were designed for fabricating different types of tailored surface textures using the RUT method. Surface generation mechanisms and machinable structures of the RUT process are analyzed and simulated with a 3D-CAD program. Textured surfaces generated by using a triangular pyramid cutting tip are constructed. Different textural patterns from several micrometers to several tens of micrometers with few burrs were successfully fabricated, which proved that tools with a proper two-rake-face design are capable of removing cutting chips efficiently along a sinusoidal cutting locus in the RUT process. Technical applications of the textured surfaces are also discussed. Wetting properties of textured aluminum surfaces were evaluated by combining the test of surface roughness features. The results show that the real surface area of the textured aluminum surfaces almost doubled by comparing with that of a flat surface, and anisotropic wetting properties were obtained due to the obvious directional textural features.
基金Supported by National Natural Science Foundation of China(20776058)New Century Training Programme Foundation for the Talents by the State Education Commission (NCET-06-0646)~~
文摘[Objective] The aim was to isolate and identify a taxol-producing endophytic fungus from Taxus media. [Method] 32 strains of endophytic fungi were identified form the inner bark of T. media,and their fermentation products were detected by high performance liquid chromatography (HPLC). [Result] Through the screening,a strain of taxol-producing endophytic fungi M57 was obtained,which could produce 45-50 μg/L of taxol,and M57 was defined as Rhizopus sp. through morphological observation and 18S rDNA sequence analysis. [Conclusion] The finding of Rhizopus sp. M57 provided a promising strain for producing taxol with taxol-producing fungi fermentation process.
基金the National Natural Science Foundation of China under Grant Nos.11201335,11301376,and 71573110
文摘This paper aims to derive the time-consistent investment strategy for the defined contribution(DC) pension plan under the mean-variance criterion.The financial market consists of a risk-free asset and a risky asset of which price process satisfies the constant elasticity of variance(CEV) model.Compared with the geometric Brownian motion model,the CEV model has the ability of capturing the implied volatility skew and explaining the volatility smile.The authors assume that the contribution to the pension fund is a constant proportion of the pension member's salary.Meanwhile,the salary is stochastic and its volatility arises from the price process of the risky asset,which makes the proposed model different from most of existing researches and more realistic.In the proposed model,the optimization problem can be decomposed into two sub-problems:Before and after retirement cases.By applying a game theoretic framework and solving extended Hamilton-Jacobi-Bellman(HJB) systems,the authors derive the time-consistent strategies and the corresponding value functions explicitly.Finally,numerical simulations are presented to illustrate the effects of model parameters on the time-consistent strategies.
基金supported by National Hightech R&D Program of China (863 Program) under Grant (No. 2013AA102301)Natural Science Foundation of China under Grant (No. U1536112)
文摘Publish/subscribe paradigm paves a way to integrate and serve many scalable, inter-operable Internet of Things(IoT) applications. The increasing IoT applications require new properties of publish/subscribe communication model, for example, strict quality of service(Qo S) guarantees, supporting a large number of widely distributed devices, etc. Software Defined Networking(SDN) enables personalized programming and individualized QoS supports for different applications. The combination of the two will have a good prospect. In this paper, we present an IoT-oriented communication platform which combines the publish/subscribe paradigm with SDN, aiming at establishing an IoT ecosystem to facilitate IoT services/applications accessing internet. We design the interaction logic of topic-based publish/subscribe middleware, and describe the setup and maintenance of topology information as well as event routing in detail, considering the characteristics of SDN. Finally, we exemplify its practicability with a deployed District Heating Control and Information Service System(DHCISS) and validity the effectiveness with some experiments.
基金This work was supported by a grant from the National Natural Science Foundation of China （No. 81001102）.
文摘Background Keratinoyte serum-free medium （K-SFM） is a defined medium used to support the growth of primary keratinocytes and embryonic stem cell. The aim of this research was to optimize enrichment of breast cancer stem cells （CSCs） using K-SFM. Methods＇ A K-SFM was used to enrich CSCs from two breast cancer cell lines and a primary culture of breast cancer. RPMI-1640 supplemented with 10% fetal calf serum （FCS） was used as a control. CSCs were identified with flow cytometry using CD44＋/CD24-as molecular markers. The expression of a variety of CSC markers （Oct-4, ABCG2, Nanog, N-cadherin, and E-cadherin） was analyzed with real-time PCR. Results Much higher percentage of CSCs was achieved with K-SFM： 17.3% for MCF-7 cells, 17.4% for SKBR-3, and 20.0% for primary breast cancer culture. Less than 1% CSC was achieved using RPMI-1640 supplemented with 10% FCS. In comparison to the CSCs obtained with RPMI-1640, CSCs in the K-SFM expressed higher levels of Oct-4, ABCG2, Nanog and N-cadherin, and lower level of E-cadherin. Conclusion K-SFM is an optimal culture medium to maintain and to enrich breast CSCs.
文摘针对典型蜂窝网络LTE-A网络的切换认证问题,本文通过引入SDN(Software Defined Network,软件定义网络),提出了软件定义LTE-A异构网络架构,在中心控制器中共享UE(User Equipment,用户设备)的安全上下文信息,以实现简化切换认证过程,提高认证效率的目标.中心控制器的加入,使蜂窝与核心网通信时需要增加一次信令开销,而LTE-A网络的标准切换认证方法过于复杂,应用在软件定义LTE-A异构网络中,会产生较多的信令开销.基于代理签名的切换认证方法,使UE在验证身份时不用经过核心网,减少了信令开销.在安全性相同的情况下,基于椭圆曲线的加密体系比基于RSA的加密体系计算量更小,有利于减少中心控制器的计算压力.本文采用椭圆曲线代理签名方法,提出了一种新型的切换认证协议,并运用着色Petri网进行建模和仿真分析.仿真结果表明,该协议是有效的,且安全性更高.
文摘An improved and efficient DEM-CFD approach is developed for spouted beds. A nonlinear Discrete Element Method （DEM）, with a concept of spring, dash-pot and friction slider, is used for tracing the movement of each individual particle. The gas flow is described by a set of reorganized governing equations. Two phases are coupled through contributions due to effects of porosity, viscosity and drag. All equations are solved with the commercial package Fluent with an implementation of User Defined Functions （UDF）. To validate the improved model, a two-dimensional conical-base spouted bed is chosen as a case study. An unstructured mesh system is adopted instead of regular grid system. The simulation also takes the Saffman force and Magnus effect into account. The calculation results show good agreement with the experimental observations which are taken from the literature.
文摘With the continuous expansion of the data center network scale, changing network requirements, and increasing pressure on network bandwidth, the traditional network architecture can no longer meet people’s needs. The development of software defined networks has brought new opportunities and challenges to future networks. The data and control separation characteristics of SDN improve the performance of the entire network. Researchers have integrated SDN architecture into data centers to improve network resource utilization and performance. This paper first introduces the basic concepts of SDN and data center networks. Then it discusses SDN-based load balancing mechanisms for data centers from different perspectives. Finally, it summarizes and looks forward to the study on SDN-based load balancing mechanisms and its development trend.
文摘Traditional traffic management techniques appear to be incompetent in complex data center networks, so proposes a load balancing strategy based on Long Short-Term Memory (LSTM) and quantum annealing by Software Defined Network (SDN) to dynamically predict the traffic and comprehensively consider the current and predicted load of the network in order to select the optimal forwarding path and balance the network load. Experiments have demonstrated that the algorithm achieves significant improvement in both system throughput and average packet loss rate for the purpose of improving network quality of service.
基金supported in part by the Project of National Network Cyberspace Security (Grant No.2017YFB0803204)the National High-Tech Research and Development Program of China (863 Program) (Grant No. 2015AA016102)+1 种基金Foundation for Innovative Research Group of the National Natural Science Foundation of China (Grant No.61521003)Foundation for the National Natural Science Foundation of China (Grant No. 61502530)
文摘Software Defined Networking(SDN) provides flexible network management by decoupling control plane and data plane. However, such separation introduces the issues regarding the reliability of the control plane and controller load imbalance in the distributed SDN network, which will cause the low network stability and the poor controller performance. This paper proposes Reliable and Load balance-aware Multi-controller Deployment(RLMD) strategy to address the above problems. Firstly, we establish a multiple-controller network model and define the relevant parameters for RLMD. Then, we design the corresponding algorithms to implement this strategy. By weighing node efficiency and path quality, Controller Placement Selection(CPS) algorithm is introduced to explore the reliable deployments of the controllers. On this basis, we design Multiple Domain Partition(MDP) algorithm to allocate switches for controllers according to node attractability and controller load balancing rate, which could realize the reasonable domain planning. Finally, the simulations show that, compared with the typical strategies, RLMD has the better performance in improving the reliability of the control plane and balancing the distribution of the controller loads.
