The polysaccharide,adenosine and mannitol components of Cordyceps taii collected from the wild were determined,and the effects of aqueous C.taii extracts on immune functions in mice were investigated using carbon clea...The polysaccharide,adenosine and mannitol components of Cordyceps taii collected from the wild were determined,and the effects of aqueous C.taii extracts on immune functions in mice were investigated using carbon clearance and delayed-type hypersensitivity testing(DTH),and by determining thymic and splenic indices.Polysaccharide,adenosine and mannitol levels in C.taii were 36.20 mg/g,0.27 mg/g and 80.20 mg/g,respectively.Aqueous C.taii extracts partially alleviated the suppressive effects on the thymic and splenic indices caused by cyclophosphamide,and increased nonspecific immunity and cellular immune functions.Toxicity tests revealed that the LD50 for aqueous C.taii extract on oral administration was >69.42 g/kg.展开更多
本文报道了戴氏虫草(Cordyceps taii Liang et Liu)的无性型,戴氏绿僵菌(Metarhizium taii Liang et Liu)88-601菌株水溶性胞外多糖(CD-1)的免疫调节作用和多糖的组成及液体培养的条件。结果表明,CD-1经提取、分离、纯化表明它是均一性...本文报道了戴氏虫草(Cordyceps taii Liang et Liu)的无性型,戴氏绿僵菌(Metarhizium taii Liang et Liu)88-601菌株水溶性胞外多糖(CD-1)的免疫调节作用和多糖的组成及液体培养的条件。结果表明,CD-1经提取、分离、纯化表明它是均一性的葡聚糖,分子量约200,000,产量为13.5 g/l(纯多糖)。有免疫调节作用。菌丝生长的适宜温度范围为25～29℃。37℃时分生胞子不萌发,菌丝产量和粗多糖产量最高的培养基为黄豆粉葡萄糖培养液(SGM)(分别为1.24g/100ml,16.75g/l)。粗多糖纯度可达80％。展开更多
基金the Foundation of Guangdong Province(No.2005B33701016 and No.2006B20201038)
文摘The polysaccharide,adenosine and mannitol components of Cordyceps taii collected from the wild were determined,and the effects of aqueous C.taii extracts on immune functions in mice were investigated using carbon clearance and delayed-type hypersensitivity testing(DTH),and by determining thymic and splenic indices.Polysaccharide,adenosine and mannitol levels in C.taii were 36.20 mg/g,0.27 mg/g and 80.20 mg/g,respectively.Aqueous C.taii extracts partially alleviated the suppressive effects on the thymic and splenic indices caused by cyclophosphamide,and increased nonspecific immunity and cellular immune functions.Toxicity tests revealed that the LD50 for aqueous C.taii extract on oral administration was >69.42 g/kg.
文摘本文报道了戴氏虫草(Cordyceps taii Liang et Liu)的无性型,戴氏绿僵菌(Metarhizium taii Liang et Liu)88-601菌株水溶性胞外多糖(CD-1)的免疫调节作用和多糖的组成及液体培养的条件。结果表明,CD-1经提取、分离、纯化表明它是均一性的葡聚糖,分子量约200,000,产量为13.5 g/l(纯多糖)。有免疫调节作用。菌丝生长的适宜温度范围为25～29℃。37℃时分生胞子不萌发,菌丝产量和粗多糖产量最高的培养基为黄豆粉葡萄糖培养液(SGM)(分别为1.24g/100ml,16.75g/l)。粗多糖纯度可达80％。
