目的:测定评价Mapi Research Trust授权的便秘患者生存质量自评量表PAC-QOL中文版的信度、效度和反应度.方法:通过测定283例罗马Ⅲ标准诊断的功能性便秘患者的生存质量对PAC-QOL中文版进行评价.结果:通过探索性因子分析,量表可分为生理...目的:测定评价Mapi Research Trust授权的便秘患者生存质量自评量表PAC-QOL中文版的信度、效度和反应度.方法:通过测定283例罗马Ⅲ标准诊断的功能性便秘患者的生存质量对PAC-QOL中文版进行评价.结果:通过探索性因子分析,量表可分为生理、社会心理、担忧和满意度4个公因子,与原版量表基本一致;各条目与其所属领域的相关性有显著统计学意义(P<0.01);各领域及总分的内在信度Cronbachα系数除生理维度为0.69外,其余均在0.70以上;治疗1mo后与治疗前相比,各维度得分和总分有显著统计学差异(P<0.01);便秘患者治疗前与健康人群相比,各维度得分和总分有显著统计学差异(P<0.01).结论:PAC-QOL中文版具有较好的信度、效度和反应度,可用于中国便秘患者生存质量的测定.展开更多
AIM: To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls.METHODS: Constipation was diagnosed by Rome Ⅱ criteria.Coping ability and anxiety/depre...AIM: To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls.METHODS: Constipation was diagnosed by Rome Ⅱ criteria.Coping ability and anxiety/depression were assessed by validated questionnaires. Transit time and balloon distension test were performed.RESULTS: 34.5% patients were classified as slow transit type of constipation. The total colonic transit time (56 h vs 10 h, P＜0.0001) and rectal sensation including urge sensation (79 mL vs 63 mL, P = 0.019) and maximum tolerable volume (110 mL vs95 mL, P = 0.03) differed in patients and controls. Constipated subjects had significantly higher anxiety and depression scores and lower SF-36 scores in all categories. They also demonstrated higher scores of'monitoring' coping strategy (14+6 vs9+3, P = 0.001),which correlated with the rectal distension sensation (P = 0.005), urge sensation (P=0.002), and maximum tolerable volume (P = 0.035). The less use of blunting strategy predicted slow transit constipation in both univariate (P = 0.01) and multivariate analysis (P = 0.03).CONCLUSION: Defective or ineffective use of coping strategies may be an important etiology in functional constipation and subsequently reflected in abnormal anorectal physiology.展开更多
文摘目的:测定评价Mapi Research Trust授权的便秘患者生存质量自评量表PAC-QOL中文版的信度、效度和反应度.方法:通过测定283例罗马Ⅲ标准诊断的功能性便秘患者的生存质量对PAC-QOL中文版进行评价.结果:通过探索性因子分析,量表可分为生理、社会心理、担忧和满意度4个公因子,与原版量表基本一致;各条目与其所属领域的相关性有显著统计学意义(P<0.01);各领域及总分的内在信度Cronbachα系数除生理维度为0.69外,其余均在0.70以上;治疗1mo后与治疗前相比,各维度得分和总分有显著统计学差异(P<0.01);便秘患者治疗前与健康人群相比,各维度得分和总分有显著统计学差异(P<0.01).结论:PAC-QOL中文版具有较好的信度、效度和反应度,可用于中国便秘患者生存质量的测定.
文摘AIM: To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls.METHODS: Constipation was diagnosed by Rome Ⅱ criteria.Coping ability and anxiety/depression were assessed by validated questionnaires. Transit time and balloon distension test were performed.RESULTS: 34.5% patients were classified as slow transit type of constipation. The total colonic transit time (56 h vs 10 h, P＜0.0001) and rectal sensation including urge sensation (79 mL vs 63 mL, P = 0.019) and maximum tolerable volume (110 mL vs95 mL, P = 0.03) differed in patients and controls. Constipated subjects had significantly higher anxiety and depression scores and lower SF-36 scores in all categories. They also demonstrated higher scores of'monitoring' coping strategy (14+6 vs9+3, P = 0.001),which correlated with the rectal distension sensation (P = 0.005), urge sensation (P=0.002), and maximum tolerable volume (P = 0.035). The less use of blunting strategy predicted slow transit constipation in both univariate (P = 0.01) and multivariate analysis (P = 0.03).CONCLUSION: Defective or ineffective use of coping strategies may be an important etiology in functional constipation and subsequently reflected in abnormal anorectal physiology.
