When variations occur in the water content or dry bulk density of soil,the contact angle hysteresis will affect the soil-water characteristic curve(SWCC).The occurrence of the contact angle hysteresis can be divided i...When variations occur in the water content or dry bulk density of soil,the contact angle hysteresis will affect the soil-water characteristic curve(SWCC).The occurrence of the contact angle hysteresis can be divided into slipping and pinning.It is difficult to determine the effect of pinning existence on SWCC by tests.In this study,the effect of contact angle hysteresis on SWCC was analyzed either in the case of no variations in soil dry bulk density with changes in soil water content or no variations in soil water content with changes in soil dry bulk density.In both cases,soil particles were simplified to the spherical particle model.Based on the geometrically mechanic relationship between the particles and connecting liquid bridges,a physical model for predicting the SWCC was derived from the spherical particle model.Adjusting parameters made the model applicable to various soils,that is,the cohesive soil was considered as micron-sized spherical particles.Through the simulations on SWCC test data of sand,silt,clay,and swelling soil,it was confirmed that the physical model possessed good reliability and practicability.Finally,the analysis of rationality of contact angle was performed based on the basic assumptions of the model.展开更多
Interaction of the T cell receptor(TCR)with an MHC-antigenic peptide complex results in changes at the molecular and cellular levels in T cells.The outside environmental cues are translated into various signal transdu...Interaction of the T cell receptor(TCR)with an MHC-antigenic peptide complex results in changes at the molecular and cellular levels in T cells.The outside environmental cues are translated into various signal transduction pathways within the cell,which mediate the activation of various genes with the help of specific transcription factors.These signaling networks propagate with the help of various effector enzymes,such as kinases,phosphatases,and phospholipases.Integration of these disparate signal transduction pathways is done with the help of adaptor proteins that are non-enzymatic in function and that serve as a scaffold for various protein-protein interactions.This process aids in connecting the proximal to distal signaling pathways,thereby contributing to the full activation of T cells.This review provides a comprehensive snapshot of the various molecules involved in regulating T cell receptor signaling,covering both enzymes and adaptors,and will discuss their role in human disease.展开更多
Semi-solid squeeze casting（SSSC） and liquid squeeze casting（LSC） processes were used to fabricate a ZL104 connecting rod, and the influences of the process parameters on the microstructures and mechanical properti...Semi-solid squeeze casting（SSSC） and liquid squeeze casting（LSC） processes were used to fabricate a ZL104 connecting rod, and the influences of the process parameters on the microstructures and mechanical properties were investigated. Results showed that the tensile strength and elongation of the SSSC-fabricated rod were improved by 22% and 17%, respectively, compared with those of the LSC-fabricated rod. For SSSC, the average particle size（APS） and the shape factor（SF） increased with the increase of re-melting temperature（Tr）, whereas the tensile strength and elongation increased first and then decreased. The APS increased with increasing the mold temperature（Tm）, whereas the SF increased initially and then decreased, which caused the tensile strength and elongation to increase initially and then decrease. The APS decreased and the SF increased as squeezing pressure（ps） increased, and the mechanical properties were enhanced. Moreover, the optimal Tr, ps and Tm are 848 K, 100 MPa and 523 K, respectively.展开更多
Semantic refinement of stakeholders＇ requirements is a fundamental issue in requirements engineering. Facing with the on-demand collaboration problem among the heterogeneous, autonomous, and dynamic service resources...Semantic refinement of stakeholders＇ requirements is a fundamental issue in requirements engineering. Facing with the on-demand collaboration problem among the heterogeneous, autonomous, and dynamic service resources in the Web, service requirements refinement becomes extremely important, and the key issue in service requirements refinement is semantic interoperability aggregation. A method for creating connecting ontologies driven by requirement sign ontology is proposed. Based on connecting ontologies, a method for semantic interoperability aggregation in requirements refinement is proposed. In addition, we discover that the necessary condition for semantic interoperability is semantic similarity, and the sufficient condition is the coverability of the agreed mediation ontology. Based on this viewpoint, a metric framework for calculating semantic interoperability capability is proposed. This methodology can provide a semantic representation mechanism for refining users＇ requirements; meanwhile, since users＇ requirements in the Web usually originate from different domains, it can also provide semantic interoperability guidance for networked service discovery, and is an effective approach for the realization of on-demand service integration. The methodology will be beneficial in service-oriented software engineering and cloud computing.展开更多
The influences of power spinning process parameters on the mechanical properties of spinning parts were analyzed with an SXD100/3-CNC numerical control power spinning machine.The unidirectional tensile tests were carr...The influences of power spinning process parameters on the mechanical properties of spinning parts were analyzed with an SXD100/3-CNC numerical control power spinning machine.The unidirectional tensile tests were carried out.Based on the experimental data,a ternary quadratic regression equation was established by orthogonal experiment.The Ramberg-Osgood constitutive model of tin-bronze connecting rod bushing was obtained.Referred to the constitutive relation of macroscopic incremental,the incremental elastoplastic constitutive relation of spinning parts was deduced based on the Mises yield criterion and kinematic hardening model.The results can be applied to the elastoplastic analysis in finite element numerical simulation.展开更多
基金Supported by the National Natural Science Foundation of China (No. 50979028)the Program of the Chinese Ministry of Water Resources (No. 200801065)
文摘When variations occur in the water content or dry bulk density of soil,the contact angle hysteresis will affect the soil-water characteristic curve(SWCC).The occurrence of the contact angle hysteresis can be divided into slipping and pinning.It is difficult to determine the effect of pinning existence on SWCC by tests.In this study,the effect of contact angle hysteresis on SWCC was analyzed either in the case of no variations in soil dry bulk density with changes in soil water content or no variations in soil water content with changes in soil dry bulk density.In both cases,soil particles were simplified to the spherical particle model.Based on the geometrically mechanic relationship between the particles and connecting liquid bridges,a physical model for predicting the SWCC was derived from the spherical particle model.Adjusting parameters made the model applicable to various soils,that is,the cohesive soil was considered as micron-sized spherical particles.Through the simulations on SWCC test data of sand,silt,clay,and swelling soil,it was confirmed that the physical model possessed good reliability and practicability.Finally,the analysis of rationality of contact angle was performed based on the basic assumptions of the model.
基金This research was supported by the Crafoord Foundationthe Swedish Cancer Societythe Swedish Childhood Cancer Foundation.
文摘Interaction of the T cell receptor(TCR)with an MHC-antigenic peptide complex results in changes at the molecular and cellular levels in T cells.The outside environmental cues are translated into various signal transduction pathways within the cell,which mediate the activation of various genes with the help of specific transcription factors.These signaling networks propagate with the help of various effector enzymes,such as kinases,phosphatases,and phospholipases.Integration of these disparate signal transduction pathways is done with the help of adaptor proteins that are non-enzymatic in function and that serve as a scaffold for various protein-protein interactions.This process aids in connecting the proximal to distal signaling pathways,thereby contributing to the full activation of T cells.This review provides a comprehensive snapshot of the various molecules involved in regulating T cell receptor signaling,covering both enzymes and adaptors,and will discuss their role in human disease.
基金Project(51335009)supported by the National Natural Science Foundation of ChinaProject(2014JQ7273)supported by the Natural Science Foundation of Shaanxi Province of ChinaProject(CXY1514(1))supported by the Xi’an Science and Technology Plan Projects,China
文摘Semi-solid squeeze casting（SSSC） and liquid squeeze casting（LSC） processes were used to fabricate a ZL104 connecting rod, and the influences of the process parameters on the microstructures and mechanical properties were investigated. Results showed that the tensile strength and elongation of the SSSC-fabricated rod were improved by 22% and 17%, respectively, compared with those of the LSC-fabricated rod. For SSSC, the average particle size（APS） and the shape factor（SF） increased with the increase of re-melting temperature（Tr）, whereas the tensile strength and elongation increased first and then decreased. The APS increased with increasing the mold temperature（Tm）, whereas the SF increased initially and then decreased, which caused the tensile strength and elongation to increase initially and then decrease. The APS decreased and the SF increased as squeezing pressure（ps） increased, and the mechanical properties were enhanced. Moreover, the optimal Tr, ps and Tm are 848 K, 100 MPa and 523 K, respectively.
基金supported by the National Basic Research 973 Program of China under Grant No.2007CB310801the National Natural Science Foundation of China under Grant Nos.60970017 and 60903034
文摘Semantic refinement of stakeholders＇ requirements is a fundamental issue in requirements engineering. Facing with the on-demand collaboration problem among the heterogeneous, autonomous, and dynamic service resources in the Web, service requirements refinement becomes extremely important, and the key issue in service requirements refinement is semantic interoperability aggregation. A method for creating connecting ontologies driven by requirement sign ontology is proposed. Based on connecting ontologies, a method for semantic interoperability aggregation in requirements refinement is proposed. In addition, we discover that the necessary condition for semantic interoperability is semantic similarity, and the sufficient condition is the coverability of the agreed mediation ontology. Based on this viewpoint, a metric framework for calculating semantic interoperability capability is proposed. This methodology can provide a semantic representation mechanism for refining users＇ requirements; meanwhile, since users＇ requirements in the Web usually originate from different domains, it can also provide semantic interoperability guidance for networked service discovery, and is an effective approach for the realization of on-demand service integration. The methodology will be beneficial in service-oriented software engineering and cloud computing.
基金Project(2012011023-2)supported by the Natural Science Foundation of Shanxi Province,China
文摘The influences of power spinning process parameters on the mechanical properties of spinning parts were analyzed with an SXD100/3-CNC numerical control power spinning machine.The unidirectional tensile tests were carried out.Based on the experimental data,a ternary quadratic regression equation was established by orthogonal experiment.The Ramberg-Osgood constitutive model of tin-bronze connecting rod bushing was obtained.Referred to the constitutive relation of macroscopic incremental,the incremental elastoplastic constitutive relation of spinning parts was deduced based on the Mises yield criterion and kinematic hardening model.The results can be applied to the elastoplastic analysis in finite element numerical simulation.
