目的系统评价认知行为疗法对改善HIV感染者和AIDS患者抑郁,提高服药依从性和生活质量的效果。方法计算机检索h e Cochrane Library(2013年第4期)、Ovid-JBI、PubMed、EMbase、PsycARTICLES、CBM和CNKI数据库,收集关于认知行为疗法对改善...目的系统评价认知行为疗法对改善HIV感染者和AIDS患者抑郁,提高服药依从性和生活质量的效果。方法计算机检索h e Cochrane Library(2013年第4期)、Ovid-JBI、PubMed、EMbase、PsycARTICLES、CBM和CNKI数据库,收集关于认知行为疗法对改善HIV感染者和AIDS患者抑郁,提高服药依从性和生活质量的随机对照试验,检索时限均为建库至2013年4月30日。由2名研究者按照纳入与排除标准筛选文献、提取资料并评价质量后,采用RevMan 5.2软件进行Meta分析。结果共纳入17个研究,2 163例患者。Meta分析结果显示,认知行为疗法在6个月内能够改善HIV感染者和AIDS患者的抑郁[SMD=–0.26,95%CI(–0.41,–0.10),P=0.001]和提高患者生活质量[SMD=–0.57,95%CI(–1.04,–0.11),P=0.02],也能提高患者长期服药依从性[WMD=3.98,95%CI(1.67,6.30),P=0.000 8]。结论认知行为疗法对改善HIV感染者和AIDS患者的抑郁和提高生活质量具有较好的短期效果,对提高服药依从性具有长期效果。展开更多
AIM To review available evidence on the use of cognitive behavioural therapy(CBT) for treating obsessive compulsive disorder co-occurring with psychosis.METHODS In this paper we present a detailed and comprehensive re...AIM To review available evidence on the use of cognitive behavioural therapy(CBT) for treating obsessive compulsive disorder co-occurring with psychosis.METHODS In this paper we present a detailed and comprehensive review of the current literature focusing on CBT treatment of obsessive compulsive disorder(OCD) co-occurring with schizophrenia or schizoaffective disorder. We identified relevant literature published between 2001 and May 2016 through MEDLINE/PubM ed search using as search string("obsessive compulsive disorders" or "obsessive compulsive symptoms") and("schizophrenia" or "schizoaffective disorder" or "psychosis") and("cognitive behavioural therapy"). Other citations of interest were further identified from references reported in the accessed articles. The search was limited to studies written in English and carried out in adult patients. A total of 9 studies, 8 case reports and 1 case series, were found.RESULTS The reviewed evidence indicates that CBT is:(1) safe, i.e., does not worsen psychotic symptoms;(2) well accepted, with a discontinuation rate quite similar to that reported for patients with OCD without psychosis comorbidity;(3) effective, with a symptom reduction quite similar to that reported for patients with OCD without psychosis and for SRIs treatment of OCD cooccurring with psychosis; and(4) effective in patients with OCD induced by second-generation antipsychotic as well as in patients with OCD not induced by secondgeneration antipsychotic. Alcohol/substance use disorder comorbidity and OCD onset preceding that of SCH/SA was predictors of poor outcome. These results are derived only by additional studies with adequate sample size.CONCLUSION Our results support the use of CBT for OCD in patients with psychosis.展开更多
Objectives: In the present study, we set out to establish whether executive function in everyday life is impaired in obsessive-compulsive disorder patients, and if it is more impaired (or not) in patients who relapsed...Objectives: In the present study, we set out to establish whether executive function in everyday life is impaired in obsessive-compulsive disorder patients, and if it is more impaired (or not) in patients who relapsed after cognitive behavioural therapy than in treatment-na?ve obsessive-compulsive disorder patients. Method: The Behavior Rating Inventory of Executive Function— Adult Version (BRIEF-A) was used to measure executive function in everyday life in three groups of 19 participants: treatment-na?ve obsessive-compulsive disorderpatients, obsessive-compulsive disorder patients having relapsed after CBT, and healthy controls. Results: The BRIEF-A results revealed an impairment in executive function in the treatment-na?ve and relapsed obsessive-compulsive disorder groups, relative to the healthy control group. There was no significant difference in executive function between the two groups of patients. Conclusions: These results show that impaired executive function is not associated with relapse in patients with obsessive-compulsive disorder having undergone cognitive behavioural therapy.展开更多
基金Supported by "Fondazione dell’Istituto di Psicopatologia Onlus",Rome,Italy
文摘AIM To review available evidence on the use of cognitive behavioural therapy(CBT) for treating obsessive compulsive disorder co-occurring with psychosis.METHODS In this paper we present a detailed and comprehensive review of the current literature focusing on CBT treatment of obsessive compulsive disorder(OCD) co-occurring with schizophrenia or schizoaffective disorder. We identified relevant literature published between 2001 and May 2016 through MEDLINE/PubM ed search using as search string("obsessive compulsive disorders" or "obsessive compulsive symptoms") and("schizophrenia" or "schizoaffective disorder" or "psychosis") and("cognitive behavioural therapy"). Other citations of interest were further identified from references reported in the accessed articles. The search was limited to studies written in English and carried out in adult patients. A total of 9 studies, 8 case reports and 1 case series, were found.RESULTS The reviewed evidence indicates that CBT is:(1) safe, i.e., does not worsen psychotic symptoms;(2) well accepted, with a discontinuation rate quite similar to that reported for patients with OCD without psychosis comorbidity;(3) effective, with a symptom reduction quite similar to that reported for patients with OCD without psychosis and for SRIs treatment of OCD cooccurring with psychosis; and(4) effective in patients with OCD induced by second-generation antipsychotic as well as in patients with OCD not induced by secondgeneration antipsychotic. Alcohol/substance use disorder comorbidity and OCD onset preceding that of SCH/SA was predictors of poor outcome. These results are derived only by additional studies with adequate sample size.CONCLUSION Our results support the use of CBT for OCD in patients with psychosis.
文摘Objectives: In the present study, we set out to establish whether executive function in everyday life is impaired in obsessive-compulsive disorder patients, and if it is more impaired (or not) in patients who relapsed after cognitive behavioural therapy than in treatment-na?ve obsessive-compulsive disorder patients. Method: The Behavior Rating Inventory of Executive Function— Adult Version (BRIEF-A) was used to measure executive function in everyday life in three groups of 19 participants: treatment-na?ve obsessive-compulsive disorderpatients, obsessive-compulsive disorder patients having relapsed after CBT, and healthy controls. Results: The BRIEF-A results revealed an impairment in executive function in the treatment-na?ve and relapsed obsessive-compulsive disorder groups, relative to the healthy control group. There was no significant difference in executive function between the two groups of patients. Conclusions: These results show that impaired executive function is not associated with relapse in patients with obsessive-compulsive disorder having undergone cognitive behavioural therapy.
