The current epidemic of non-alcoholic fatty liver disease(NAFLD) is reshaping the field of hepatology all around the world.The widespread diffusion of metabolic risk factors such as obesity,type2-diabetes mellitus,and...The current epidemic of non-alcoholic fatty liver disease(NAFLD) is reshaping the field of hepatology all around the world.The widespread diffusion of metabolic risk factors such as obesity,type2-diabetes mellitus,and dyslipidemia has led to a worldwide diffusion of NAFLD.In parallel to the increased availability of effective anti-viral agents,NAFLD is rapidly becoming the most common cause of chronic liver disease in Western Countries,and a similar trend is expected in Eastern Countries in the next years.This epidemic and its consequences have prompted experts from all over the word in identifying effective strategies for the diagnosis,management,and treatment of NAFLD.Different scientific societies from Europe,America,and Asia-Pacific regions have proposed guidelines based on the most recent evidence about NAFLD.These guidelines are consistent with the key elements in the management of NAFLD,but still,show significant difference about some critical points.We reviewed the current literature in English language to identify the most recent scientific guidelines about NAFLD with the aim to find and critically analyse the main differences.We distinguished guidelines from 5 different scientific societies whose reputation is worldwide recognised and who are representative of the clinical practice in different geographical regions.Differences were noted in: the definition of NAFLD,the opportunity of NAFLD screening in high-risk patients,the noninvasive test proposed for the diagnosis of NAFLD and the identification of NAFLD patients with advanced fibrosis,in the follow-up protocols and,finally,in the treatment strategy(especially in the proposed pharmacological management).These difference have been discussed in the light of the possible evolution of the scenario ofNAFLD in the next years.展开更多
美国眼科临床指南(Preferred Practice Pattern,PPP)是美国眼科学会定期组织专家在广泛审阅发表文献的基础上所编制的眼科诊疗指南,是目前国际公认的权威眼科诊疗指南。白内障手术的最新PPP《成人白内障手术》于2016年发布,内容涵盖了...美国眼科临床指南(Preferred Practice Pattern,PPP)是美国眼科学会定期组织专家在广泛审阅发表文献的基础上所编制的眼科诊疗指南,是目前国际公认的权威眼科诊疗指南。白内障手术的最新PPP《成人白内障手术》于2016年发布,内容涵盖了成人白内障手术相关各个方面的诊疗常规和最新进展。我们组织了我院从事白内障和晶状体疾病经验丰富的专家组成员,立足国内实际,对这一新版PPP进行深入解读,帮助国内医师充分理解和切实应用。我们的PPP解读已获人民卫生出版社的立项支持,初稿现已完成。本文介绍了我们进行PPP解读的出发点、解读的具体内容,并与读者提前分享若干PPP重要更新的解读要点。展开更多
文摘The current epidemic of non-alcoholic fatty liver disease(NAFLD) is reshaping the field of hepatology all around the world.The widespread diffusion of metabolic risk factors such as obesity,type2-diabetes mellitus,and dyslipidemia has led to a worldwide diffusion of NAFLD.In parallel to the increased availability of effective anti-viral agents,NAFLD is rapidly becoming the most common cause of chronic liver disease in Western Countries,and a similar trend is expected in Eastern Countries in the next years.This epidemic and its consequences have prompted experts from all over the word in identifying effective strategies for the diagnosis,management,and treatment of NAFLD.Different scientific societies from Europe,America,and Asia-Pacific regions have proposed guidelines based on the most recent evidence about NAFLD.These guidelines are consistent with the key elements in the management of NAFLD,but still,show significant difference about some critical points.We reviewed the current literature in English language to identify the most recent scientific guidelines about NAFLD with the aim to find and critically analyse the main differences.We distinguished guidelines from 5 different scientific societies whose reputation is worldwide recognised and who are representative of the clinical practice in different geographical regions.Differences were noted in: the definition of NAFLD,the opportunity of NAFLD screening in high-risk patients,the noninvasive test proposed for the diagnosis of NAFLD and the identification of NAFLD patients with advanced fibrosis,in the follow-up protocols and,finally,in the treatment strategy(especially in the proposed pharmacological management).These difference have been discussed in the light of the possible evolution of the scenario ofNAFLD in the next years.
文摘美国眼科临床指南(Preferred Practice Pattern,PPP)是美国眼科学会定期组织专家在广泛审阅发表文献的基础上所编制的眼科诊疗指南,是目前国际公认的权威眼科诊疗指南。白内障手术的最新PPP《成人白内障手术》于2016年发布,内容涵盖了成人白内障手术相关各个方面的诊疗常规和最新进展。我们组织了我院从事白内障和晶状体疾病经验丰富的专家组成员,立足国内实际,对这一新版PPP进行深入解读,帮助国内医师充分理解和切实应用。我们的PPP解读已获人民卫生出版社的立项支持,初稿现已完成。本文介绍了我们进行PPP解读的出发点、解读的具体内容,并与读者提前分享若干PPP重要更新的解读要点。
