基金Canadian Institute of Health Research CCI-92216:MOP 62823国家自然科学基金资助国际合作交流项目(30811120439) Acknowledgements The research on frailty has been supported by the Canadian Institutes of Health Research and by the Fountain Innovation Fund of the Queen Elizabeth Ⅱ Health Sciences Foundation. Professor Kenneth Rockwood receives career support through Foundation as the Dalhousie the Kathryn Medical Research Allen Weldon Professor of Alzheimer Research. The CanadaChina Collaboration is funded jointly by the Canadian Institutes for Health Research and the National Natural Science Foundation of China ( CIHR CCI-92216 : MOP62823 and NSFC30811120439). This paper is written as part of that collaboration. References