In this paper, we propose a schistosomiasis model in which two human groups share the water contaminated by schistosomiasis and migrate each other. The dynamical behavior of the model is studied. By calculation, the t...In this paper, we propose a schistosomiasis model in which two human groups share the water contaminated by schistosomiasis and migrate each other. The dynamical behavior of the model is studied. By calculation, the threshold value is given, which determines whether the disease will be extinct or not. The existence and global stability of the parasite-free equilibrium and the locally stability of the endemic equilibrium are discussed. Numerical simulations indicate that the diffusion from the mild endemic village to severe endemic village is benefit to control schistosomiasis transmission;otherwise it is bad for the disease control.展开更多
In this paper,an HIV dynamics model with the proliferation of CD4 T cells is proposed.The authors consider nonnegativity,boundedness,global asymptotic stability of the solutions and bifurcation properties of the stead...In this paper,an HIV dynamics model with the proliferation of CD4 T cells is proposed.The authors consider nonnegativity,boundedness,global asymptotic stability of the solutions and bifurcation properties of the steady states.It is proved that the virus is cleared from the host under some conditions if the basic reproduction number R0 is less than unity.Meanwhile,the model exhibits the phenomenon of backward bifurcation.We also obtain one equilibrium is semi-stable by using center manifold theory.It is proved that the endemic equilibrium is globally asymptotically stable under some conditions if R0 is greater than unity.It also is proved that the model undergoes Hopf bifurcation from the endemic equilibrium under some conditions.It is novelty that the model exhibits two famous bifurcations,backward bifurcation and Hopf bifurcation.The model is extended to incorporate the specific Cytotoxic T Lymphocytes(CTLs)immune response.Stabilities of equilibria and Hopf bifurcation are considered accordingly.In addition,some numerical simulations for justifying the theoretical analysis results are also given in paper.展开更多
文摘In this paper, we propose a schistosomiasis model in which two human groups share the water contaminated by schistosomiasis and migrate each other. The dynamical behavior of the model is studied. By calculation, the threshold value is given, which determines whether the disease will be extinct or not. The existence and global stability of the parasite-free equilibrium and the locally stability of the endemic equilibrium are discussed. Numerical simulations indicate that the diffusion from the mild endemic village to severe endemic village is benefit to control schistosomiasis transmission;otherwise it is bad for the disease control.
基金The Teacher Research Capacity Promotion Program of Beijing Normal University Zhuhaithe NSF(11871108)of China
文摘In this paper,an HIV dynamics model with the proliferation of CD4 T cells is proposed.The authors consider nonnegativity,boundedness,global asymptotic stability of the solutions and bifurcation properties of the steady states.It is proved that the virus is cleared from the host under some conditions if the basic reproduction number R0 is less than unity.Meanwhile,the model exhibits the phenomenon of backward bifurcation.We also obtain one equilibrium is semi-stable by using center manifold theory.It is proved that the endemic equilibrium is globally asymptotically stable under some conditions if R0 is greater than unity.It also is proved that the model undergoes Hopf bifurcation from the endemic equilibrium under some conditions.It is novelty that the model exhibits two famous bifurcations,backward bifurcation and Hopf bifurcation.The model is extended to incorporate the specific Cytotoxic T Lymphocytes(CTLs)immune response.Stabilities of equilibria and Hopf bifurcation are considered accordingly.In addition,some numerical simulations for justifying the theoretical analysis results are also given in paper.
