目的:分析儿童爆发性心肌炎(fulminant myocarditis,FM)的3.0T心脏磁共振(cardiac magnetic resonance,CMR)表现,探讨其在FM早期诊断及短期预后中的价值。方法:以2016年1月~2018年1月在我院收治的20例FM患儿为研究对象,所有FM患者在入...目的:分析儿童爆发性心肌炎(fulminant myocarditis,FM)的3.0T心脏磁共振(cardiac magnetic resonance,CMR)表现,探讨其在FM早期诊断及短期预后中的价值。方法:以2016年1月~2018年1月在我院收治的20例FM患儿为研究对象,所有FM患者在入院时及治疗后各进行1次CMR检查,观察入院时及治疗后患者的临床表现、CMR表现(心脏结构及功能、心肌组织特性)及短期预后情况。结果:入院及治疗后CMR检查时患儿的cTNT及BNP水平、IVST、LVEF、LVM、ESV、LVEDD、T2比值及LGE范围比较差异有统计学意义(P<0.05)。入院CMR检查时,20例患儿为EGE,17例患儿为LGE及T2信号增加,15例患心肌增厚,10例患儿LVEF增高;治疗后CMR检查时,5例患儿为LGE,1例患儿为T2信号增加,1例患儿LVEF增高。短期预后完全恢复患儿的Ⅲ度房室传导阻滞发生率未完全恢复患儿(P<0.05)、LGE面积小于未完全恢复患儿(P<0.05)。结论:CMR对儿童FM早期诊断的敏感性高,特征性强,用于儿童FM的早期诊断及短期预后评估的价值高。展开更多
Amyloidosis, an infiltrative disease characterized by deposition of high molecular weight insoluble protein has a low detection rate and poor prognosis with congestive heart failure being the most common cause of deat...Amyloidosis, an infiltrative disease characterized by deposition of high molecular weight insoluble protein has a low detection rate and poor prognosis with congestive heart failure being the most common cause of death. Although definitive diagnosis is based on endomyocardial biopsy, this is rarely performed due to procedural risk and sampling error. Traditional non-invasive imaging, such as transthoracic echocardiography (TTE) and electrocardiogram (ECG) lacks sensitivity detecting the disease in its early stages. This case report demonstrates the utility of cardiac Magnetic Resonance Imaging in addition to traditional imaging modalities in this often clinically challenging problem.展开更多
文摘目的:分析儿童爆发性心肌炎(fulminant myocarditis,FM)的3.0T心脏磁共振(cardiac magnetic resonance,CMR)表现,探讨其在FM早期诊断及短期预后中的价值。方法:以2016年1月~2018年1月在我院收治的20例FM患儿为研究对象,所有FM患者在入院时及治疗后各进行1次CMR检查,观察入院时及治疗后患者的临床表现、CMR表现(心脏结构及功能、心肌组织特性)及短期预后情况。结果:入院及治疗后CMR检查时患儿的cTNT及BNP水平、IVST、LVEF、LVM、ESV、LVEDD、T2比值及LGE范围比较差异有统计学意义(P<0.05)。入院CMR检查时,20例患儿为EGE,17例患儿为LGE及T2信号增加,15例患心肌增厚,10例患儿LVEF增高;治疗后CMR检查时,5例患儿为LGE,1例患儿为T2信号增加,1例患儿LVEF增高。短期预后完全恢复患儿的Ⅲ度房室传导阻滞发生率未完全恢复患儿(P<0.05)、LGE面积小于未完全恢复患儿(P<0.05)。结论:CMR对儿童FM早期诊断的敏感性高,特征性强,用于儿童FM的早期诊断及短期预后评估的价值高。
文摘Amyloidosis, an infiltrative disease characterized by deposition of high molecular weight insoluble protein has a low detection rate and poor prognosis with congestive heart failure being the most common cause of death. Although definitive diagnosis is based on endomyocardial biopsy, this is rarely performed due to procedural risk and sampling error. Traditional non-invasive imaging, such as transthoracic echocardiography (TTE) and electrocardiogram (ECG) lacks sensitivity detecting the disease in its early stages. This case report demonstrates the utility of cardiac Magnetic Resonance Imaging in addition to traditional imaging modalities in this often clinically challenging problem.
