AIM: To assess the prognostic significance of immunological and nutritional-based indices, including the prognostic nutritional index(PNI), neutrophillymphocyte ratio(NLR), and platelet-lymphocyte ratio in gastric can...AIM: To assess the prognostic significance of immunological and nutritional-based indices, including the prognostic nutritional index(PNI), neutrophillymphocyte ratio(NLR), and platelet-lymphocyte ratio in gastric cancer.METHODS: We retrospectively reviewed 632 gastric cancer patients who underwent gastrectomy between1998 and 2008. Areas under the receiver operating characteristic curve were calculated to compare the predictive ability of the indices, together with estimating the sensitivity, specificity and agreement rate.Univariate and multivariate analyses were performed to identify risk factors for overall survival(OS). Propensity score analysis was performed to adjust variables to control for selection bias.RESULTS: Each index could predict OS in gastric cancer patients in univariate analysis, but only PNI had independent prognostic significance in multivariate analysis before and after adjustment with propensity scoring(hazard ratio, 1.668; 95% confidence interval:1.368-2.035). In subgroup analysis, a low PNI predicted a significantly shorter OS in patients with stage Ⅱ-Ⅲ disease(P = 0.019, P < 0.001), T3-T4 tumors(P <0.001), or lymph node metastasis(P < 0.001). Canton score, a combination of PNI, NLR, and platelet, was a better indicator for OS than PNI, with the largest area under the curve for 12-, 36-, 60-mo OS and overall OS(P = 0.022, P = 0.030, P < 0.001, and P = 0.024,respectively). The maximum sensitivity, specificity, and agreement rate of Canton score for predicting prognosis were 84.6%, 34.9%, and 70.1%, respectively.CONCLUSION: PNI is an independent prognostic factor for OS in gastric cancer. Canton score can be a novel preoperative prognostic index in gastric cancer.展开更多
An English-Chinese Dictionary （ 咭唎国译语, Ying Ji Li Guo Yi Yii） and A Portuguese-Chinese Dictionary （播时都噶礼雅话, Bo Lti Duo Ga Li Ya Hua） are reckoned as the coUative dictionaries compiled by the Office of ...An English-Chinese Dictionary （ 咭唎国译语, Ying Ji Li Guo Yi Yii） and A Portuguese-Chinese Dictionary （播时都噶礼雅话, Bo Lti Duo Ga Li Ya Hua） are reckoned as the coUative dictionaries compiled by the Office of Interpreters and Translators （会同四译馆, Hui Tong Si Yi Guan） in Qianlong time （1748）, Qing dynasty. There is only one original manuscript of these books gathered and preserved by the Palace Museum. In the present paper, we intent to introduce the significant value and detailed information of these two official collative dictionaries from social background, process of compilation, and stylistic basis of the book. Meanwhile, we will primarily work out the phonetic principles between Canton dialect and foreign languages also indicate the dialect characteristics after clarifying the faults and errors. The present paper may supply with a rudimentary knowing and resource to the realm of ＂Canton English＂ and ＂Canton Portuguese＂, even to the social status and Chinese dialect in Canton area for certain period. Detailed and specific research, especially for A Portuguese-Chinese Dictionary, still lies for future discovery.展开更多
This paper presents an effective approach for updating finite element dynamic model from incomplete modal data identified from ambient vibration measurements.The proposed method is based on the relationship between th...This paper presents an effective approach for updating finite element dynamic model from incomplete modal data identified from ambient vibration measurements.The proposed method is based on the relationship between the perturbation of structural parameters such as stiffness and mass changes and the modal data measurements of the tested structure such as measured mode shape readings.Structural updating parameters including both stiffness and mass parameters are employed to represent the differences in structural parameters between the finite element model and the associated tested structure.These updating parameters are then evaluated by an iterative solution procedure,giving optimised solutions in the least squares sense without requiring an optimisation technique.In order to reduce the influence of modal measurement uncertainty,the truncated singular value decomposition regularization method incorporating the quasi-optimality criterion is employed to produce reliable solutions for the structural updating parameters.Finally,the numerical investigations of a space frame structure and the practical applications to the Canton Tower benchmark problem demonstrate that the proposed method can correctly update the given finite element model using the incomplete modal data identified from the recorded ambient vibration measurements.展开更多
“Get up!We’re going to have morning tea.”I guess you must be familiar with this saying if you’re Cantonese.The culture of tea has been deeply integrated(融入)into the daily life of Cantonese.
基金Supported by National Natural Science Foundation of China,Nos.81101865 and 81272637Doctoral Fund of the Ministry of Education of China,No.20110171120064+1 种基金Natural Science Foundation of Guangdong Province,No.S2013020012724Clinical Medicine Research Project 5010 of Sun Yat-sen University,No.2010006
文摘AIM: To assess the prognostic significance of immunological and nutritional-based indices, including the prognostic nutritional index(PNI), neutrophillymphocyte ratio(NLR), and platelet-lymphocyte ratio in gastric cancer.METHODS: We retrospectively reviewed 632 gastric cancer patients who underwent gastrectomy between1998 and 2008. Areas under the receiver operating characteristic curve were calculated to compare the predictive ability of the indices, together with estimating the sensitivity, specificity and agreement rate.Univariate and multivariate analyses were performed to identify risk factors for overall survival(OS). Propensity score analysis was performed to adjust variables to control for selection bias.RESULTS: Each index could predict OS in gastric cancer patients in univariate analysis, but only PNI had independent prognostic significance in multivariate analysis before and after adjustment with propensity scoring(hazard ratio, 1.668; 95% confidence interval:1.368-2.035). In subgroup analysis, a low PNI predicted a significantly shorter OS in patients with stage Ⅱ-Ⅲ disease(P = 0.019, P < 0.001), T3-T4 tumors(P <0.001), or lymph node metastasis(P < 0.001). Canton score, a combination of PNI, NLR, and platelet, was a better indicator for OS than PNI, with the largest area under the curve for 12-, 36-, 60-mo OS and overall OS(P = 0.022, P = 0.030, P < 0.001, and P = 0.024,respectively). The maximum sensitivity, specificity, and agreement rate of Canton score for predicting prognosis were 84.6%, 34.9%, and 70.1%, respectively.CONCLUSION: PNI is an independent prognostic factor for OS in gastric cancer. Canton score can be a novel preoperative prognostic index in gastric cancer.
文摘An English-Chinese Dictionary （ 咭唎国译语, Ying Ji Li Guo Yi Yii） and A Portuguese-Chinese Dictionary （播时都噶礼雅话, Bo Lti Duo Ga Li Ya Hua） are reckoned as the coUative dictionaries compiled by the Office of Interpreters and Translators （会同四译馆, Hui Tong Si Yi Guan） in Qianlong time （1748）, Qing dynasty. There is only one original manuscript of these books gathered and preserved by the Palace Museum. In the present paper, we intent to introduce the significant value and detailed information of these two official collative dictionaries from social background, process of compilation, and stylistic basis of the book. Meanwhile, we will primarily work out the phonetic principles between Canton dialect and foreign languages also indicate the dialect characteristics after clarifying the faults and errors. The present paper may supply with a rudimentary knowing and resource to the realm of ＂Canton English＂ and ＂Canton Portuguese＂, even to the social status and Chinese dialect in Canton area for certain period. Detailed and specific research, especially for A Portuguese-Chinese Dictionary, still lies for future discovery.
文摘This paper presents an effective approach for updating finite element dynamic model from incomplete modal data identified from ambient vibration measurements.The proposed method is based on the relationship between the perturbation of structural parameters such as stiffness and mass changes and the modal data measurements of the tested structure such as measured mode shape readings.Structural updating parameters including both stiffness and mass parameters are employed to represent the differences in structural parameters between the finite element model and the associated tested structure.These updating parameters are then evaluated by an iterative solution procedure,giving optimised solutions in the least squares sense without requiring an optimisation technique.In order to reduce the influence of modal measurement uncertainty,the truncated singular value decomposition regularization method incorporating the quasi-optimality criterion is employed to produce reliable solutions for the structural updating parameters.Finally,the numerical investigations of a space frame structure and the practical applications to the Canton Tower benchmark problem demonstrate that the proposed method can correctly update the given finite element model using the incomplete modal data identified from the recorded ambient vibration measurements.
文摘“Get up!We’re going to have morning tea.”I guess you must be familiar with this saying if you’re Cantonese.The culture of tea has been deeply integrated(融入)into the daily life of Cantonese.
