AIM: To investigate two distinct clinical phenotypes of reflux esophagitis and intra-hernial ulcer (Cameron lesions) in patients with large hiatal hernias. METHODS: A case series study was performed with 16 831 patien...AIM: To investigate two distinct clinical phenotypes of reflux esophagitis and intra-hernial ulcer (Cameron lesions) in patients with large hiatal hernias. METHODS: A case series study was performed with 16 831 patients who underwent diagnostic esophagogastroduodenoscopy for 2 years at an academic referral center. A hiatus diameter ≥ 4 cm was defined as a large hernia. A sharp fold that surrounded the cardia was designated as an intact gastroesophageal flap valve (GEFV), and a loose fold or disappearance of the fold was classified as an impaired GEFV. We studied the associations between large hiatal hernias and the distinct clinical phenotypes (reflux esophagitis and Cameron lesions), and analyzed factors that distinguished the clinical phenotypes. RESULTS: Large hiatal hernias were found in 49 (0.3%) of 16 831 patients. Cameron lesions and reflux esopha-gitis were observed in 10% and 47% of these patients, and 0% and 8% of the patients without large hiatal hernias, which indicated significant associations between large hiatal hernias and these diseases. However, there was no coincidence of the two distinct disorders. Univariate analysis demonstrated significant associations between Cameron lesions and the clinico-endoscopic factors such as nonsteroidal anti-inflammatory drug (NSAID) intake (80% in Cameron lesion cases vs 18% in non-Cameron lesion cases, P=0.015) and intact GEFV (100% in Cameron lesion cases vs 18% in non-Cameron lesion cases, P=0.0007). In contrast, reflux esophagitis was linked with impaired GEFV (44% in reflux esophagitis cases vs 8% in non-reflux esophagitis cases, P = 0.01). Multivariate regression analysis confirmed these significant associations. CONCLUSION: GEFV status and NSAID intake distinguish clinical phenotypes of large hiatal hernias. Cameron lesions are associated with intact GEFV and NSAID intake.展开更多
In this paper,a detection method combining Cameron decomposition based on polarization scattering characteristics in sea clutter background is proposed.Firstly,the Cameron decomposition is exploited to fuse the radar ...In this paper,a detection method combining Cameron decomposition based on polarization scattering characteristics in sea clutter background is proposed.Firstly,the Cameron decomposition is exploited to fuse the radar echoes of full polarization channels at the data level.Due to the artificial material structure on the surface of the target,it can be shown that the non-reciprocity of the target cell is stronger than that of the clutter cell.Then,based on the analysis of the decomposition results,a new feature with scattering geometry characteristics in polarization domain,denoted as Cameron polarization decomposition scattering weight(CPD-SW),is extracted as the test statistic,which can achieve more detailed descriptions of the clutter scattering characteristics utilizing the difference between their scattering types.Finally,the superiority of the proposed CPD-SW detector over traditional detectors in improving detection performance is verified by the IPIX measured dataset,which has strong stability under short-time observation in threshold detection and can also improve the separability of feature space zin anomaly detection.展开更多
There are many factors influencing landslide occurrence.The key for landslide control is to confirm the regional landslide hazard factors.The Cameron Highlands of Malaysia was selected as the study area.By bivariate s...There are many factors influencing landslide occurrence.The key for landslide control is to confirm the regional landslide hazard factors.The Cameron Highlands of Malaysia was selected as the study area.By bivariate statistical analysis method with GIS software the authors analyzed the relationships among landslides and environmental factors such as lithology,geomorphy,elevation,road and land use.Distance Evaluation Model was developed with Landslide Density(LD).And the assessment of landslide hazard of Cameron Highlands was performed.The result shows that the model has higher prediction precision.展开更多
Cameron Mounger and I have been friendssince we were teenagers.Both of us liked music,and several years after we left high school,Cambecame *a disc jockey.Recently he told me the story about the day hewas down to his ...Cameron Mounger and I have been friendssince we were teenagers.Both of us liked music,and several years after we left high school,Cambecame *a disc jockey.Recently he told me the story about the day hewas down to his last dollar.It was the day his luck—and his life—changed.展开更多
The policy of encouraging agriculture and development for mass tourism has led to environmental problems in Cameron Highlands,Malaysia.Rampant development and land clearing have significantly altered the land cover of...The policy of encouraging agriculture and development for mass tourism has led to environmental problems in Cameron Highlands,Malaysia.Rampant development and land clearing have significantly altered the land cover of Cameron Highlands for the past 30 years.Sensitive highlands areas are prone to landslides and soil erosion which then contributed to the main water pollution issues in the network of river system,sedimentation and siltation.The continuous trend of river water quality deterioration in Cameron Highlands has raised the issues for discussion in this review article.The purpose of this review is to briefly summarize the land use change,agriculture practices,agro-tourism,and agriculture policy and management toward water quality of the river system network in Cameron Highlands specifically in the downtown where most of the development and agriculture activities are concentrated.A rigorous review has been done on the existing literature to determine the relationship between land use change and agriculture practices toward river water quality in Cameron Highlands from 2001 to 2017.The total number of reviewed papers was 68.The outcomes established from previous researchers have highlighted factors such as soil erosion,landslides,agriculture activities,urbanization,and unplanned development associated with land use change have significantly influenced the river water quality in the highland areas.Continuous land use changes without proper development plan and law enforcement may critically threaten the sustainability of river network in the highlands area.展开更多
There is ample clinical evidence suggesting that the presence of large axial or paraesophageal hernias may lead to iron deficiency anemia.So-called Cameron lesions,as well as other small mucosa erosions,in the sliding...There is ample clinical evidence suggesting that the presence of large axial or paraesophageal hernias may lead to iron deficiency anemia.So-called Cameron lesions,as well as other small mucosa erosions,in the sliding area of these diaphragmatic hernias lead to invisible chronic blood loss and consequently to iron depletion.While the spectrum of symptoms in these patients is large,anemia is often not the only indication and typically not the primary indication for surgical correction of diaphragmatic hernias.Drug treatment with proton pump inhibitors and iron substitution can alleviate anemia,but this is not always successful.To exclude other possible bleeding sources in the gastrointestinal tract,a comprehensive diagnostic program is necessary and reviewed in this manuscript.Additionally,we discuss controversies in the surgical management of paraesophageal hernias.展开更多
Cameron lesions represent linear gastric erosions and ulcers on the crests of mucosal folds in the distal neck of a hiatal hernia(HH).Such lesions may be found in upto 50% of endoscopies performed for another indicati...Cameron lesions represent linear gastric erosions and ulcers on the crests of mucosal folds in the distal neck of a hiatal hernia(HH).Such lesions may be found in upto 50% of endoscopies performed for another indication.Though typically asymptomatic,these may rarely present as acute,severe upper gastrointestinal bleed(GIB).The aim is to report a case of a non-anemic 87-year-old female with history of HH and atrial fibrillation who presented with hematemesis and melena resulting in hypovolemic shock.Repeat esophagogastroduodenoscopy was required to identify multiple Cameron ulcers as the source.Endoscopy in a patient with HH should involve meticulous visualization of hernia neck and surrounding mucosa.Cameron ulcers should be considered in all patients with severe,acute GIB and especially in those with known HH with or without chronic anemia.展开更多
詹姆斯·卡梅隆James Cameron对许多观众来说,这是一个如雷贯耳的导演名字;对更多的观众来说,听到这个名字的时候很难马上反应过来。但假如罗列出他的作品,那么除非是不爱看电影的人,否则哪怕没有看过,至少也是听说过。詹姆斯·...詹姆斯·卡梅隆James Cameron对许多观众来说,这是一个如雷贯耳的导演名字;对更多的观众来说,听到这个名字的时候很难马上反应过来。但假如罗列出他的作品,那么除非是不爱看电影的人,否则哪怕没有看过,至少也是听说过。詹姆斯·卡梅隆,是一位真正可以用"地球人都知道"这句话来形容的电影导演,冠在他身上的名字大多不那么好听:"暴君"、"烧钱机器"、"技术狂人"……但也正因为有了他这样的人,电影才得以一直充满创新与激情,激发人们观影的渴望。而尽管他难以合作的名声远播,但他的作品却屡屡创造辉煌,在当今四位能多次制造数亿票房的顶级导演(乔治·卢卡斯、史提芬·斯皮尔伯格、彼得·杰克逊及詹姆斯·卡梅隆)中,他是单片产出最高的一位。在全球票房榜上排名第二的《指环王3》(The Lordof Ring:Return of The King )和《变形金刚》(TheTransformers)两者的票房相加,才能比得上其缔造影史纪录的《泰坦尼克号》(Titanic)所攫取的票房。而从现在开始,卡梅隆又为世人带来了一部重量级的电影《阿凡达》(Avatar)!展开更多
Dealing with water resources issues requires understanding of the community perception. It is important to create a communicative partnership between community and government towards sustainable water resources manage...Dealing with water resources issues requires understanding of the community perception. It is important to create a communicative partnership between community and government towards sustainable water resources management. Opinion survey is an essential step to gather the point of view from local community. However, it always generates a large and complex dataset that are difficult to be interpreted by decision maker. In order to overcome this difficulty, statistical methods are applied to develop an interpretability model for decision maker. This study demonstrated the application of Descriptive Analysis and Principle Factor Analysis （PFA） to reduce the complexity of opinion survey dataset by revealing underlying information. A total of 106 respondents were interviewed; consisting of 68 male and 38 female respondents respectively. This study first applied descriptive analysis to identify the basic score for each variable, and these variables are soil erosion （68.9%）, degradation of water quality （65.1%）, degradation of freshwater ecosystem （61.0%）, water shortage （50%）, agricultural solid waste problem （46.2%）, water borne diseases （23.6%）, illegal land clearing （21.7%）, legal land clearing （15.1%）, uncontrolled river water abstraction in upstream （54.7%））, poor solid waste management （34.0%）, low awareness of local community （61.3%）, haphazard planning and development （74.5%） and administration mistake （37.0%）. Based on the PFA result, a total of four rotated factors were extracted, representing different aspects of water related issues in Cameron Highlands. Factor 1, 2, 3 and 4 were summarised to four topics namely： （1） water environment degradation caused by illegal solid waste disposal and low awareness of community, （2） agricultural development leading to negative impacts on water resources such as water shortage and ecosystem deterioration, （3） land clearing activity leading to serious land erosion （4） human health problem due to e展开更多
文摘AIM: To investigate two distinct clinical phenotypes of reflux esophagitis and intra-hernial ulcer (Cameron lesions) in patients with large hiatal hernias. METHODS: A case series study was performed with 16 831 patients who underwent diagnostic esophagogastroduodenoscopy for 2 years at an academic referral center. A hiatus diameter ≥ 4 cm was defined as a large hernia. A sharp fold that surrounded the cardia was designated as an intact gastroesophageal flap valve (GEFV), and a loose fold or disappearance of the fold was classified as an impaired GEFV. We studied the associations between large hiatal hernias and the distinct clinical phenotypes (reflux esophagitis and Cameron lesions), and analyzed factors that distinguished the clinical phenotypes. RESULTS: Large hiatal hernias were found in 49 (0.3%) of 16 831 patients. Cameron lesions and reflux esopha-gitis were observed in 10% and 47% of these patients, and 0% and 8% of the patients without large hiatal hernias, which indicated significant associations between large hiatal hernias and these diseases. However, there was no coincidence of the two distinct disorders. Univariate analysis demonstrated significant associations between Cameron lesions and the clinico-endoscopic factors such as nonsteroidal anti-inflammatory drug (NSAID) intake (80% in Cameron lesion cases vs 18% in non-Cameron lesion cases, P=0.015) and intact GEFV (100% in Cameron lesion cases vs 18% in non-Cameron lesion cases, P=0.0007). In contrast, reflux esophagitis was linked with impaired GEFV (44% in reflux esophagitis cases vs 8% in non-reflux esophagitis cases, P = 0.01). Multivariate regression analysis confirmed these significant associations. CONCLUSION: GEFV status and NSAID intake distinguish clinical phenotypes of large hiatal hernias. Cameron lesions are associated with intact GEFV and NSAID intake.
基金supported by the National Natural Science Foundation of China(62201251)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(22KJB510024)the Open Fund for the Hangzhou Institute of Technology Academician Workstation at Xidian University(XH-KY-202306-0291)。
文摘In this paper,a detection method combining Cameron decomposition based on polarization scattering characteristics in sea clutter background is proposed.Firstly,the Cameron decomposition is exploited to fuse the radar echoes of full polarization channels at the data level.Due to the artificial material structure on the surface of the target,it can be shown that the non-reciprocity of the target cell is stronger than that of the clutter cell.Then,based on the analysis of the decomposition results,a new feature with scattering geometry characteristics in polarization domain,denoted as Cameron polarization decomposition scattering weight(CPD-SW),is extracted as the test statistic,which can achieve more detailed descriptions of the clutter scattering characteristics utilizing the difference between their scattering types.Finally,the superiority of the proposed CPD-SW detector over traditional detectors in improving detection performance is verified by the IPIX measured dataset,which has strong stability under short-time observation in threshold detection and can also improve the separability of feature space zin anomaly detection.
基金Supported by Project of the National High Technology Research and Development Program of China(No.2002AA130020)
文摘There are many factors influencing landslide occurrence.The key for landslide control is to confirm the regional landslide hazard factors.The Cameron Highlands of Malaysia was selected as the study area.By bivariate statistical analysis method with GIS software the authors analyzed the relationships among landslides and environmental factors such as lithology,geomorphy,elevation,road and land use.Distance Evaluation Model was developed with Landslide Density(LD).And the assessment of landslide hazard of Cameron Highlands was performed.The result shows that the model has higher prediction precision.
文摘Cameron Mounger and I have been friendssince we were teenagers.Both of us liked music,and several years after we left high school,Cambecame *a disc jockey.Recently he told me the story about the day hewas down to his last dollar.It was the day his luck—and his life—changed.
基金Financial support for this study was provided by the National Hydraulic Research Institute of Malaysia(NAHRIM)Sumitomo Foundation Research Grant(Reg.No.168401-41).
文摘The policy of encouraging agriculture and development for mass tourism has led to environmental problems in Cameron Highlands,Malaysia.Rampant development and land clearing have significantly altered the land cover of Cameron Highlands for the past 30 years.Sensitive highlands areas are prone to landslides and soil erosion which then contributed to the main water pollution issues in the network of river system,sedimentation and siltation.The continuous trend of river water quality deterioration in Cameron Highlands has raised the issues for discussion in this review article.The purpose of this review is to briefly summarize the land use change,agriculture practices,agro-tourism,and agriculture policy and management toward water quality of the river system network in Cameron Highlands specifically in the downtown where most of the development and agriculture activities are concentrated.A rigorous review has been done on the existing literature to determine the relationship between land use change and agriculture practices toward river water quality in Cameron Highlands from 2001 to 2017.The total number of reviewed papers was 68.The outcomes established from previous researchers have highlighted factors such as soil erosion,landslides,agriculture activities,urbanization,and unplanned development associated with land use change have significantly influenced the river water quality in the highland areas.Continuous land use changes without proper development plan and law enforcement may critically threaten the sustainability of river network in the highlands area.
文摘There is ample clinical evidence suggesting that the presence of large axial or paraesophageal hernias may lead to iron deficiency anemia.So-called Cameron lesions,as well as other small mucosa erosions,in the sliding area of these diaphragmatic hernias lead to invisible chronic blood loss and consequently to iron depletion.While the spectrum of symptoms in these patients is large,anemia is often not the only indication and typically not the primary indication for surgical correction of diaphragmatic hernias.Drug treatment with proton pump inhibitors and iron substitution can alleviate anemia,but this is not always successful.To exclude other possible bleeding sources in the gastrointestinal tract,a comprehensive diagnostic program is necessary and reviewed in this manuscript.Additionally,we discuss controversies in the surgical management of paraesophageal hernias.
文摘Cameron lesions represent linear gastric erosions and ulcers on the crests of mucosal folds in the distal neck of a hiatal hernia(HH).Such lesions may be found in upto 50% of endoscopies performed for another indication.Though typically asymptomatic,these may rarely present as acute,severe upper gastrointestinal bleed(GIB).The aim is to report a case of a non-anemic 87-year-old female with history of HH and atrial fibrillation who presented with hematemesis and melena resulting in hypovolemic shock.Repeat esophagogastroduodenoscopy was required to identify multiple Cameron ulcers as the source.Endoscopy in a patient with HH should involve meticulous visualization of hernia neck and surrounding mucosa.Cameron ulcers should be considered in all patients with severe,acute GIB and especially in those with known HH with or without chronic anemia.
文摘詹姆斯·卡梅隆James Cameron对许多观众来说,这是一个如雷贯耳的导演名字;对更多的观众来说,听到这个名字的时候很难马上反应过来。但假如罗列出他的作品,那么除非是不爱看电影的人,否则哪怕没有看过,至少也是听说过。詹姆斯·卡梅隆,是一位真正可以用"地球人都知道"这句话来形容的电影导演,冠在他身上的名字大多不那么好听:"暴君"、"烧钱机器"、"技术狂人"……但也正因为有了他这样的人,电影才得以一直充满创新与激情,激发人们观影的渴望。而尽管他难以合作的名声远播,但他的作品却屡屡创造辉煌,在当今四位能多次制造数亿票房的顶级导演(乔治·卢卡斯、史提芬·斯皮尔伯格、彼得·杰克逊及詹姆斯·卡梅隆)中,他是单片产出最高的一位。在全球票房榜上排名第二的《指环王3》(The Lordof Ring:Return of The King )和《变形金刚》(TheTransformers)两者的票房相加,才能比得上其缔造影史纪录的《泰坦尼克号》(Titanic)所攫取的票房。而从现在开始,卡梅隆又为世人带来了一部重量级的电影《阿凡达》(Avatar)!
文摘Dealing with water resources issues requires understanding of the community perception. It is important to create a communicative partnership between community and government towards sustainable water resources management. Opinion survey is an essential step to gather the point of view from local community. However, it always generates a large and complex dataset that are difficult to be interpreted by decision maker. In order to overcome this difficulty, statistical methods are applied to develop an interpretability model for decision maker. This study demonstrated the application of Descriptive Analysis and Principle Factor Analysis （PFA） to reduce the complexity of opinion survey dataset by revealing underlying information. A total of 106 respondents were interviewed; consisting of 68 male and 38 female respondents respectively. This study first applied descriptive analysis to identify the basic score for each variable, and these variables are soil erosion （68.9%）, degradation of water quality （65.1%）, degradation of freshwater ecosystem （61.0%）, water shortage （50%）, agricultural solid waste problem （46.2%）, water borne diseases （23.6%）, illegal land clearing （21.7%）, legal land clearing （15.1%）, uncontrolled river water abstraction in upstream （54.7%））, poor solid waste management （34.0%）, low awareness of local community （61.3%）, haphazard planning and development （74.5%） and administration mistake （37.0%）. Based on the PFA result, a total of four rotated factors were extracted, representing different aspects of water related issues in Cameron Highlands. Factor 1, 2, 3 and 4 were summarised to four topics namely： （1） water environment degradation caused by illegal solid waste disposal and low awareness of community, （2） agricultural development leading to negative impacts on water resources such as water shortage and ecosystem deterioration, （3） land clearing activity leading to serious land erosion （4） human health problem due to e
